We’ve talked a huge amount the past 18 months, for obvious reasons, about the way that white blood cells protect us from infection. But red blood cells – it’s probably among the earliest things I learned in human biology that they’re simple bags for carrying oxygen around the body. But over recent years, immunologist Nilam Mangalmurti, University of Pennsylvania, has been finding several clues to challenge that dogma – including molecules on the surface of red blood cells known from other parts of the immune system. The Last Ice Area, home to the oldest and thickest ice in the Arctic, is expected to act as the last refuge for ice-dependent wildlife as the rest of the Arctic melts. Kent Moore, University of Toronto-Mississauga, tells us that the formation of a 3,000 square kilometre rift in the area means the ice is not as resilient as we once thought.Also on the programme, an obituary for the renowned Dutch climate scientist and physicist Geert Jan van Oldenborgh (October 22, 1961 – October 12, 2021), and, Dominique Gonçalves, Gorongosa National Park, explains how ivory poaching during the Mozambican civil war led to the rapid evolution of tusklessness in African elephants.Image: Confocal microscopy of CpG-treated human RBCs stained for Band 3. Credit: Mangalmurti Lab / Nilam Mangalmurti, MD)Presenter: Roland Pease Producer: Samara Linton

Since its introduction four decades ago, Spartina alterniflora, a salt-water cordgrass from the USA, has been spreading along China’s coasts. Today, it covers nearly half of the country’s salt marshes. As the UN Biodiversity Conference COP 15 kicks off in China, we look at how this invasive plant species threatens native species in protected coastal wetlands. Featuring Yuan Lin, East China Normal University, and Qiang He, Fudan University. In January 2020, Barney Graham and Jason McLellan teamed up to engineer a coronavirus spike protein that now powers the COVID-19 vaccines for Moderna, Pfizer, Johnson & Johnson and Novavax. They discuss their work, a next-generation vaccine using chicken eggs, and the future of pandemic preparedness. Also, a recent Nature survey reveals the extent of abuse against scientists who speak about COVID-19 publicly. Deepti Gurdasani, Queen Mary University of London, shares her experiences of trolling and online abuse and discusses the implications for academia and scientific discourse going forward.And Tom Scott explains how his team uses novel robots and sensors to go into and create 3D digital radiation maps of the Chornobyl Nuclear Power Plant and surrounding areas.(Credit: Getty Images)Presenter: Roland Pease Producer: Samara Linton

In December 2020, China's Chang'e-5 mission returned to earth carrying rock samples collected from the moon – the first lunar samples to be collected since the American Apollo and Luna missions to the moon in the 1970s. Laboratory analysis has revealed that these are the youngest samples of rocks to be collected from the moon. Lunar geologist Katherine Joy explains what this tells us about the moon’s volcanic past.Also on the programme, a recent study reveals that the hepatitis B virus has been infecting humans for at least 10,000 years. Denise Kühnert from the Max Planck Institute for the Science of Human History shares what the evolution of the virus tells us about human evolution, as well as the rise and fall of civilisations. In the wake of Cyclone Shaheen, we also speak to Princeton University’s Ning Lin about how climate modelling can help us predict tropical storms in the Arabian Sea, and Fredi Otto joins us to discuss the 2021 Nobel Prizes for Science. (Image: Getty Images) Presenter: Roland Pease Producer: Samara Linton

Since their discovery in the 1970s, artemisinin-based drugs have become the mainstay of treatment for malaria caused by the Plasmodium falciparum parasite. Researchers have identified artemisinin-resistant malaria parasites in Southeast Asia since the early 2000s, but now, there is evidence of resistance in Rwanda and Uganda. Dr Betty Balikagala of Juntendo University tells us how this resistance developed and what it means for managing malaria in Africa, which carries the greatest burden of malaria cases and deaths worldwide.We hear from some of the scientists from COVID Moonshot, a non-profit, open-science consortium which has just received key funding to develop affordable antivirals to stop SARS-CoV-2 in its tracks. Also on the programme, Dr Rakesh Ghosh from the University of California, San Francisco tells us how air pollution is contributing to 6 million preterm births globally each year, and Dr Catherine Nakalembe of the University of Maryland and Africa Lead for NASA Harvest returns to the programme as NASA/USGS launches Landsat 9.Presenter: Roland Pease Producer: Samara LintonImage: Mosquito net demonstration in a community outreach centre in Kenya Credit: Wendy Stone/Corbis via Getty Images

Researchers studying bats in Northern Laos have found evidence that brings us closer than ever to understanding the origin of Covid-19. Since the beginning of the coronavirus pandemic scientists have tried to pin-point the exact origin of Sars-CoV-2. But recent evidence from the Institut Pasteur has identified several novel coronaviruses with similarities to the current coronavirus in bats. Professor Marc Eliot spoke to Roland Pease about how this research could give us a better idea where Covid-19 came from. Could an oral Covid-19 treatment be available soon? Daria Hazuda, responsible for infectious disease and bacteria research at MSD tells us about their clinical trials for an oral antiviral drug that could combat Covid-19: Molnupiravir. Early Diagnosis of Alzheimer's Roland Pease travels to Bath to meet scientists who may have developed a way to diagnose Alzheimer's in the earlier stages of the disease. Dr George Stothart, has led the team from Bath university in the development of this simple 2 minute test. Inducing Earthquakes Scientists are experimenting with artificially managing earthquakes by injecting fluid into fault lines. Professor Derek Elsworth at Pennsylvania State University explains his research into how these induced earthquakes can be more tightly controlled. Presenter: Roland Pease Producer: Ania Lichtarowicz(Photo: Bats hanging in a cave. Credit: Getty Images)

An international team of researchers has discovered that an outbreak of Ebola in Guinea in February this year was the result of re-activated Ebola virus in someone who’d been infected at least five years ago during the earlier large Ebola epidemic that swept through Guinea, Sierra Leone and Liberia. This means the virus can remain dormant in some Ebola survivors for five years or more. Virologists Alpha Kabinet Keita and Robert Garry talk to Roland Pease about the research and its implications.Also in the programme: The eruption of lavas from Iceland’s newest volcano Fagradalsfjall continues six months on. Geochemist Ed Marshall tells us how he gets up close to sample the molten rock with a long scoop and a bucket of water, and what he’s learning about this remarkable eruption.NASA’s Katie Stack Morgan updates Science in Action on the Perseverance rover’s successful sampling of rocks from Jezero crater on the planet Mars. When the specimens are eventually returned to Earth, she says they may turn out to contain tiny samples of Mars’ water and atmosphere from early in the Red Planet’s history.(Image credit: Getty Images)Presenter: Roland Pease Producer: Andrew Luck-Baker

For the world to have a decent chance of limiting global temperature rise to 1.5 degrees, 90% of remaining coal reserves and 60% of unexploited oil and gas have to stay in the ground. These are the stark findings of carbon budget research by scientists at University College London. Dan Welsby spells out the details to Roland Pease.Virologist Ravi Gupta of the University of Cambridge describes his latest research that explains why the Delta variant of SARS-CoV-2 is much more infectious and more able to evade our immune systems and covid vaccines than other variants.When dense fog rises from the Pacific ocean into the foothills of the Andes, oases of floral colour bloom for a few weeks or months. When the fog goes, the plants die and disappear for another year or maybe another decade. The true extent of these unique ecosystems (known as fog oases or Lomas) has now been revealed by researchers at the Royal Botanic Gardens at Kew in the UK and their colleagues in Peru and Chile. They have discovered that the Lomas are much more extensive than suspected. Ecologist Carolina Tovar explains why the fog oases are threatened and need to be protected. A species of duck can now be added to the list of birds such as parrots and starlings that mimic human speech and other sounds in their environment. Listen to Ripper, the Australian musk duck who was hand-reared on a nature reserve where he learnt to imitate his keeper say ‘You bloody fool’ and imitate the sound of an aviary door closing. Animal behaviour researcher Carel ten Cate of Leiden University says that Ripper is not the only mimicking musk duck, but why this duck species has evolved this trick remains a mystery.Presenter: Roland Pease Producer: Andrew Luck-Baker(Image credit: Getty Images)

When hurricane Ida struck the coast of Louisiana last weekend, almost to the day that Katrina did 16 years ago, comparisons between the two events were soon to follow. As the latest storm continues to wreak havoc and death further north in the US, Suzana Camargo of Columbia university talks to Roland Pease about the similarities and differences, the better forecasting available now, and the grim reality that climate change suggests for this and future hurricane seasons.A couple of weeks ago, Science in Action looked at the carbon accounting of Blue Hydrogen (hydrogen manufactured from fossil fuels). Listener Nick Arndt got in touch to say we were wrong when we stated that hydrogen can’t be piped out of the ground from natural sources. His company, Sisprobe, plans to use its passive seismic prospecting technology to work with an international consortium that aims to unlock a new “hydrogen Rush” – commercialising what they suspect to be a near-ubiquitous source of genuinely carbon-free fuel - to supply the world economy of the near future. Viacheslav Zgonnik - CEO of start-up Natural Hydrogen Energy LLC - has been working on hydrogen for 10 years, has written a recent review of the science, and tells Roland about current and future studies into finding the best way to tap this simplest of molecules before it escapes into space.In Chile, the recent megadrought has led to fears that hydroelectric damns may become so drained that power-outs may occur in the coming months. This will not help Chile to achieve its target of carbon-neutrality by 2050. Apt, then, that a new Concentrated Solar Power plant (CSP) is now up and running in the north of the country. Reporter Jane Chambers has been to visit Cerro Dominador – the spectacular new array of 10,600 mirrors that focus sunshine onto a molten salt target, heating it up to 560C, and generating up to 210 MW electricity. Meanwhile archaeologists have been doing a molecular analysis of a protein found to survive in the bones of unfortunate victims of the mount Vesuvius eruption that destroyed Pompeii. Despite the searing heat that killed inhabitants of nearby Herculaneum, Oliver Criag of York University has been able to examine the different isotopes in amino acids still recoverable from their bones to help identify what sorts of things these people ate during their tragically foreshortened lifetimes. A whole lot of cereals generally, but more interestingly, the men tended to eat more fish while the women seem to have consumed more meat and dairy.(Image credit: Scott Olson/Getty Images)Presenter: Roland Pease Producer: Alex Mansfield

Indian authorities have approved the world’s first DNA-based Covid vaccine for emergency use. Not all the data that has led to the opening of the phase 3 trials is yet publicly available, but as public health policy expert Chandrakant Lahariya explains to Roland, it could be a real help in India’s, and the world’s, fight to get things under control. The origins of the Covid virus were investigated last winter by a WHO team sent to Wuhan – where the first cases were discovered – earlier this year. Their work has since become the subject of intense political scrutiny and some criticism. This week, members of the team including Marian Koopmans have written a rebuttal, setting out the original terms of the investigation and urging the continuation of the process, as she explains to Victoria Gill.Most of the science written by people from or about the African continent is written in English. Many local African languages do not currently have a meaningful vocabulary for many of the scientific terms and concepts researchers use. This week a team of scientists, journalists, and translators are completing the launch of a project called Decolonise Science, which will take 180 nominated papers posted on the website AfricaArxiv, translate them into 6 African languages including isiZulu, Sothu, and Hausa, and then use Machine Learning methods to build resources for science communication and education in people’s home languages. Project partner Sibusiso Byela explains the thinking.This week the UK’s Royal Society announced its annual awards. Kenya’s George Warimwe has taken the Africa Award for his work creating vaccines for a virus that creates disease in livestock and humans – Rift Valley Fever. His promising approach stems from years of working with adenovirus technology akin to the AstraZeneca covid virus. But as he explains, his One Health approach is to learn from the immune response in humans and apply it to animals, and vice-versa. The grant associated with the award should also help him and his team pick- up on research left-off before the coronavirus pandemic. Presenter: Roland Pease Producer: Alex Mansfield(Image: Getty Images)

The epicentre of the tragic earthquake in Haiti last week was just 100km from that of the even more deadly 2010 one. Unlike then, a network of small cheap seismic detectors run by volunteers is currently monitoring the aftershocks. As Eric Calais says, the suspicion is that this could be the latest in a sequence of quakes, echoing previous clusters over the last few hundred years. Hydrogen is being much touted as an alternative to natural gas as a source of fuel for homes in a low-carbon world. In particular, “blue” hydrogen – hydrogen made from fossil fuels but with the carbon dioxide being captured at the point of production – is said to be some sort of transitional fuel that could be introduced into current infrastructure with little stress. But Robert Howarth is less optimistic. He is co-author on a paper published last week analysing the net carbon impact of blue hydrogen production. He argues that not only are there hidden greenhouse gas emissions in production, but that in fact burning blue Hydrogen at home could have a worse impact than burning the natural gas from which it is made. Meanwhile, physicists at the US National Ignition Facility are rumoured to have made a huge stride in the quest for controlled, sustained nuclear fusion. Using a barrage of powerful lasers to heat indirectly a tiny hydrogen isotope target, on the 8th of august, they briefly got 70% of the energy back from one of their runs. It is a huge leap in returns, and tantalisingly suggests some sort of runaway fusion reaction occurred. Around the world, hopes of laser-driven fusion energy generation are soaring, but as an ecstatic Kate Lancaster of the University of York cautions, even if it does represent ignition, we are still a long way from “plug socket efficiency” or net energy gain.Meanwhile, scientists of the Leibniz Institute evolution and Biodiversity have been eavesdropping on bats in Panama. Human babies babble when they are learning how to talk. It’s been shown before that songbirds do something similar, but according to Ahana Fernandez, it now it seems another mammal joins the babbling ranks – the younglings of the Greater Sac-Winged bat of South America. Ahana tells Roland about her analysis. (Photo by Reginald Loiussaint/JR/AFP via Getty Images)Presenter: Roland Pease Producer: Alex Mansfield