Join us as we review recent articles and news featured in The DIGEST #43 and #44, including bempedoic acid to lower cardiovascular risk, Alpha-Gal Syndrome, tick bites and meat allergy, orforglipron an oral GLP1 agonist for weight loss, zuranolone for postpartum depression, DOACs for VTE of malignancy, monoclonal antibodies (mAbs) for Dementia, cytisinicline for smoking cessation, and two kiwis a day for constipation. Fill your brain hole with a delicious stack of hotcakes! Featuring Drs. Paul Williams (@PaulNWilliamz), Nora Taranto (@norataranto), and Matt Watto (@doctorwatto). Claim free CME for this episode at curbsiders.vcuhealth.org! Episodes | Subscribe | Spotify | Swag! |Mailing List | Contact | Free CME! Credits Written and Hosted by: Nora Taranto MD; Paul Williams, MD, FACP, Matthew Watto MD, FACP Cover Art: Matthew Watto MD, FACP Reviewers: Nora Taranto MD; Paul Williams, MD, FACP, Matthew Watto MD, FACP Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Sponsor: Netsuite Download NetSuite’s popular KPI Checklist, designed to give you consistently excellent performance for free, at NetSuite.com/CURBSIDERS Sponsor: Locumstory  Get a comprehensive view of locums and decide if it’s right for you at locumstory.com. Sponsor: Grammarly  Go to grammarly.com/GO to download for FREE today. Sponsor: Pathway Download the Pathway app today by visiting pathway.md Show Segments Intro, disclaimer Bempedoic Acid for CV risk reduction DOACs to prevent recurrent VTE of malignancy Cytisinicline for smoking cessation Alpha-Gal Syndrome, tick bites, and meat allergy Zuranolone for postpartum depression Orforglipron, an oral GLP1 agonist, for weight management mAbs for Alzheimer’s dementia Kiwis to prevent constipation Outro

Dr. Elliot Tapper, liver expert, walks us through the best of liver tests. He discusses targeted labs for differentiating hepatocellular versus cholestatic injury, addresses isolated lab abnormalities, and reviews causes of severe acute liver disease and issues in pregnancy. Listen and learn what 'liver function tests' really mean!

We’re taking a short summer break, but we’ll be back in September with brand-new episodes. Can’t wait? Join our Kashlak family at patreon.com/curbsiders for access to twice-monthly bonus episodes… there are already 9 of them available to feed your brain hole! Yummy! Master common hypertension scenarios in the clinic! Our guest Dr. Jordy Cohen (@jordy_bc) will lead us through the FAQs of outpatient hypertension management, including making a diagnosis of hypertension, managing blood pressure in patients with chronic kidney disease, working up refractory hypertension, and more. Free CME for this episode at curbsiders.vcuhealth.org Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Credits Writer: Matthew Watto, MD, FACP Producers: Matthew Watto, MD, FACP and Malini Gandhi Show Notes, Infographic, and Cover Art: Malini Gandhi Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Emi Okamoto MD Executive Producer: Beth Garbitelli Showrunner: Matthew Watto MD, FACP Editor: Clair Morgan of nodderly.com Guest: Jordy Cohen MD CME Partner: VCU Health CE The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org and search for this episode to claim credit. See info sheet for further directions. Note: A free VCU Health CloudCME account is required in order to seek credit. Show Segments Intro, disclaimer, guest bio Guest one-liner, Picks of the Week* Case from Kashlak: New diagnosis of hypertension How to make a diagnosis of hypertension When to start anti-hypertensive medication Initial blood pressure regimen Case from Kashlak: White coat hypertension Case from Kashlak: Hypertension in chronic kidney disease ACEis and ARBs in chronic kidney disease Diuretics in chronic kidney disease Case from Kashlak: Refractory hypertension History and initial workup for refractory hypertension Treatment of primary hyperaldosteronism Outro Sponsor: Green Chef Go to GreenChef.com/60curb and use code 60curb to get 60% off plus free shipping.

Dr. Fatima Cody Stanford, an expert in obesity medicine, reframes our approach to obesity and discusses effective medications for treatment. They explore patient goals, treatment options, including surgery and behavioral support, and the underutilization of evidence-based treatments. The episode also includes an ad for Babble language learning app.

Your swell guide to the swollen leg We’re taking a short summer break, but we’ll be back in September with brand-new episodes. Can’t wait? Join our Kashlak family at patreon.com/curbsiders for access to twice-monthly bonus episodes… there are already 9 of them available to feed your brain hole! Yummy! We have seen our esteemed guests, and they are us!  Paul Williams (@PaulNWilliamz) leads the discussion with Matt Watto (@DoctorWatto) and Beth “Garbs” Garbitelli (@bethgarbitelli) on the evaluation and management of common causes of edema. Credits Written and produced by: Paul Williams, MD, FACP Infographic and Cover Art: Matthew Watto, MD, FACP Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP; Beth Garbitelli Reviewer: Emi Okamoto, MD Executive Producer: Beth Garbitelli Showrunner: Matthew Watto, MD, FACP    Editor: Clair Morgan of nodderly.com Show Segments Intro, disclaimer Picks of the Week* The case of Lynn Fedema Pathophysiology of edema Differential diagnosis of chronic edema Chronic edema work-up Management of chronic edema Calvin Fedema and acute edema Evaluation of acute edema Outro Sponsor: Pathway Pathway is an innovative tool to improve your clinical decision-making process and enhance patient care. Download the app at pathway.md

Dr. Sara Markley Webster from Emory University discusses inpatient management of can't miss endo emergencies including adrenal crisis, myxedema coma, and thyroid storm. The topics covered include dosage and tapering of hydrocortisone, diagnostic options for adrenal insufficiency, resolving electrolyte abnormalities, clinical aids for diagnosing myxedema coma, thyroid hormone replacement, and the use of steroids in endocrine emergencies.

Ready for more knee pain?  You’ve already memorized episode #98, so join us as Ted Parks to returns to teach us even more about common causes of knee pain (anterior knee pain, patellofemoral pain, knee bursitis, pain after knee replacement) and what to do about them! Claim free CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Credits Producer: Paul Williams, MD, FACP Writer: Paul Williams, MD, FACP  Show Notes: Paul Williams, MD, FACP Infographic and Cover Art: Paul Williams, MD, FACP Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Fatima Syed MD, MSc Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Edward (Ted) Parks, MD Sponsor: Pathway Download the free Pathway app today by visiting https://www.pathway.md/ Full transcript available HERE

Hone your obesity medicine skills in primary care! We discuss overcoming barriers, patient counseling, obesity pathophysiology, motivational interviewing, tools and tips from a weight loss program, and how to discuss medications for weight loss including phentermine/topiramate, bupropion/naltrexone, orlistat, oral superabsorbent hydrogel, and GLP1 agonists. We’re joined by obesity medicine expert, Dr. Kimberly Anne Gudzune of @HopkinsMedicine, recorded @SocietyGIM #SGIM23 in Denver, Colorado  Claim free CME for this episode at curbsiders.vcuhealth.org! Show Segments Intro Barriers to treating medicine in primary care Patient counseling and obesity pathophysiology  Motivational Interviewing  Telemedicine for obesity Tools and tips for a weight loss program Medications for Obesity GLP1 agonist prescribing tips Outro Credits Written and Produced by: Matthew Watto MD, FACP Show Notes: Matthew Watto MD, FACP Cover Art and Infographic: Matthew Watto MD, FACP Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Leah Witt MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP In-studio Technical Production: Chris Chiu MD, FACP, FAAP Technical Production: PodPaste Guest: Kimberly Anne Gudzune MD, MPH

When there’s blood in the water… Work-up hematuria with confidence.  Learn what you should be worrying about, what tests are worth considering, and how to figure out if this is a job for a urologist or nephrologist. Claim free CME for this episode at https://curbsiders.vcuhealth.org! Credits Producer and writer: Paul Williams, MD, FACP Show Notes, Infographic, and Cover Art: Paul Williams, MD, FACP  Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Emi Okamoto, MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Derek Fine, MD

Join us as we review recent practice-changing articles on ketamine vs ECT for refractory depression, nonhormone treatment (fezolinetant) for menopause, metformin for long COVID, new breast cancer screening draft recommendations, and a primer on kratom.  Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto). Go to https://thecurbsiders.com for more info Become a Kashlak Memorial Hospital member and support us by joining our Patreon Claim free CME for this episode at curbsiders.vcuhealth.org!