Critical Care Reviews Podcast

Glenn Eastwood presents the results of the TAME cardiac arrest trial, investigating mild hypercapnoea post cardiac arrest. He is joined by senior investigators Alistair Nichol (Dublin) and Stephen Bernard (Melbourne). An independent editorial is delivered by Lars Andersen (Aarhus). Darren Taichman (Philadelphia) chairs a panel discussion consisting of Flavia Machado (Sao paulo), Joyce Yeung (Birmingham, UK) and Andrew Althouse (Pittsburgh), as well as the other speakers.

Profs Matthew Prekker (Minneapolis) and Matthew Semler (Nashville) present the results of the DEVICE trial, comparing direct with video laryngoscopy for emergency intubation in the critically ill. Prof Ellen O'Sullivan (Dublin) delivers an editorial, followed by a panel discussion including Prof David Harrison (London), Dr Caroline Leech (Coventry), Dr Fiona Kelly (Bath) and Prof Alistair Nichol (Dublin). The session was chaired by Dr Catriona Kelly (Dublin). These results were presented at the Critical Care Reviews Meeting 2023, held in Titanic Belfast on June 16th. The DEVICE trial was simultaneously published in the New England Journal of Medicine.

Profs Giovanni Landoni and Giacomo Monti present the results of the MERCY trial, comparing bolus administration with continuous infusion of meropenem in critically ill patients with sepsis and septic shock. The results were presented at the Critical Care Reviews Meeting 2023, in Titanic Belfast. Prof Flavia Machado (Sao Paulo) delivers an editorial. The panel discussion incldues Profs Kathy Rowan (London), Victoria Cornelius (London), Ivor Douglas (Denver) and Ewan Goligher (Toronto). The session was chaired by Chris Nutt (Belfast).

John Myburgh and Ian Seppelt  (Sydney) present the results of the SuDDICU trial at the Critical Care Reviews Meeting 2022, in Titanic Belfast. SuDDICU investigates selective digestive decontamination in critically ill mechanically ventilated patients. Naomi Hammond (Sydney) follows with a presentation of a systematic review and meta analysis also on SDD. John Marshall (Toronto) delivers an editorial. Danny McAuley (Belfast), Bodil Steen Rasmussen (Aalborg) and Victoria Cornelius (London) join the presenters for a panel discussion. The session is chaired by Chris Seymour (Pittsburgh).

Matthew Semler presents the results of the PILOT trial, comparing low, intermediate and high oxygenation targets in critically ill mechanically ventilated patients. Paul Young delivers an editorial and Chris Nutt asks questions from the viewers. The expert panel discussion includes Victoria Cornelius, Angelique de Man, Bodil Steen Rasmussen and Gilles Capellier. The paper was simultaneously published in the New England Journal of Medicine.

Prof Jan Belohlavek (Prague, Czech Republic) presents the Prague Out-of-Hospital Cardiac Arrest Study at the Critical care Reviews Meeting 2022. This study investigates the efficacy of an eCPR programme in patients with refractory out-of-hospital cardiac arrest. Dr Liz Wilcox (Toronto, Canada) follows with an editorial on the trial.

Lars Andersen (Aarhus, Denmark) presents the VAM-IHCA trial on June 15th at the Critical Care Reviews Meeting 2022, in Titanic Belfast. The VAM-IHCA trial investigates the combination of vasopressin and methylprednisolone in in-hospital cardiac arrest. Chris Seymour (Pittsburgh, USA) delivers an editorial after the trial presentation. The session is chaired by Catriona Kelly (Dublin, Ireland).

Nick Crombie (Birmingham, England) presents the RePHILL trial, comparing pre-hospital administration of saline with blood products in patients with trauma-related haemorrhagic shock.  Liz Wilcox (Toronto, Canada) delivers an editorial. The session is chaired by Catriona Kelly (Dublin, Ireland).

Derek Russell (Birmingham, USA) and Jon Casey (Nashville, USA) presents the results of the PREPARE II trial, investigating fluid bolus therapy for the prevention of cardiovascular collapse during emergency intubation. Anthony Gordon (London, England) delivers an editorial, which is followed by a panel discussion including Lennie Derde (Utrecht, the Netherlands), Andrew Althouse (Pittsburgh, USA), Elizabeth Wilcox (Toronto, Canada) and Lars Andersen (Aarhous, Denmark). The session is chaired by Chris Seymour from the USA. PREPARE II was simultaneously published in JAMA.