

Architect of Resilience
Chris Duffin
Understanding what makes this podcast different is understanding what makes Chris different.
For those who are unfamiliar, Chris' story has all the makings of a Hollywood movie: a chaotic and abusive childhood in the murderous mountains of the Pacific Northwest, graduating college while working full-time to secure custody of his siblings, achieving feats of strength no other human has ever accomplished before.
Chris' "secret formula" to overcoming those challenges? To find unstoppable strength through seemingly insurmountable struggle? It was his ability to harness his mind, body and soul. To become the architect of his own resiliency.
Throughout his journey as both athlete and academic, personally and professionally, Chris has had the pleasure of learning and sharing the intricacies of strength & resiliency with experts worldwide. These discussions with leading researchers, doctors, coaches, clinicians, and athletes have included how to;
• Achieve 'superhuman' results
• Fuel an endless evolution
• Gain internal strength and self-awareness
• Master and apply human & organizational behavior
• Utilize unparalleled injury prevention & recovery protocols
Chris would be grateful for your joining as a listener and participant in the Endless Evolution Community.
For those who are unfamiliar, Chris' story has all the makings of a Hollywood movie: a chaotic and abusive childhood in the murderous mountains of the Pacific Northwest, graduating college while working full-time to secure custody of his siblings, achieving feats of strength no other human has ever accomplished before.
Chris' "secret formula" to overcoming those challenges? To find unstoppable strength through seemingly insurmountable struggle? It was his ability to harness his mind, body and soul. To become the architect of his own resiliency.
Throughout his journey as both athlete and academic, personally and professionally, Chris has had the pleasure of learning and sharing the intricacies of strength & resiliency with experts worldwide. These discussions with leading researchers, doctors, coaches, clinicians, and athletes have included how to;
• Achieve 'superhuman' results
• Fuel an endless evolution
• Gain internal strength and self-awareness
• Master and apply human & organizational behavior
• Utilize unparalleled injury prevention & recovery protocols
Chris would be grateful for your joining as a listener and participant in the Endless Evolution Community.
Episodes
Mentioned books

Mar 26, 2025 • 58min
CM#8: Biohacking Mitochondria for Peak Performance w/ SLU-PP-332 & BAM15
In today's episode, we are diving deep into the fascinating world of biohacking mitochondrial health for peak performance. Chris Duffin is joined by guest Anthony Castor as they explore groundbreaking compounds that can enhance cellular energy and optimize your body's energy systems for better performance, longevity, and overall well-being. From understanding the vital roles of mitochondrial fission and fusion to discovering cutting-edge compounds like SLU, PP332, and BAM15, this conversation is packed with insights that can revolutionize how you view your mitochondrial health. Learn more and find the best way to source: https://chrisduffin.myshopify.com/blogs/chris-duffin-blog/bam15-the-ultimate-mitochondrial-uncoupler-for-fat-loss-energy-and-longevity Exciting insights on biohacking cellular energy for peak performance from the latest episode of the Architect of Resilience Podcast! Chris Duffin and Anthony Castor delve into mitochondrial health and how to optimize it for better performance, longevity, and wellbeing. 🎧 Here's what you'll discover: Mitochondrial Health Principles: Understand the roles of mitochondrial fission, fusion, and their impact on cellular health. These processes are key for maintaining mitochondrial quality, production, and efficient energy metabolism. Game-Changing Compounds: Explore cutting-edge compounds like BAM15 and Urolithin A. While BAM15 is a potent mitochondrial uncoupler that boosts fat burning and metabolic flexibility, Urolithin A focuses on mitophagy, ensuring efficient recycling of damaged mitochondria. Strategic Usage for Maximum Impact: Learn the importance of using these compounds strategically. Combinations like SLU PP332 on training days and BAM15 on off days can efficiently manage energy production and recovery. Are you ready to revolutionize your approach to health and performance? Check out the full episode to dive deeper into these insights! #MitochondrialHealth #Biohacking #PerformanceOptimization #PodcastTakeaways #HealthAndWellness This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Mar 4, 2025 • 59min
#27: Ali Gilbert - Leveling Up Men's Health: on Wellness, Hormones, and Overcoming Bias
We explore the nuances of men's health with renowned fitness professional Ali Gilbert. Specializing in hormonal optimization and strength training, Ali shares insights from over two decades of experience in transforming men's lives. As she discusses her journey into the niche of men's health, Ali highlights the critical role of testosterone therapy and its often overlooked benefits beyond muscles and sexual health. The podcast delves into the challenges and misconceptions surrounding testosterone therapy, coupled with insights on how hormonal health significantly impacts mental clarity, energy, and resilience. Ali also discusses the importance of optimizing one's health for peak performance, especially for entrepreneurs and professionals aiming to excel. Additionally, we touch upon her groundbreaking Silverback Summit, an event uniting medical and fitness communities to address men's health holistically. Join us for a deep dive into men's health, resilience, and what it truly means to develop strength inside and outside the gym. Check out Ali: Website: https://ali-gilbert.com IG: https://www.instagram.com/thealigilbert/?hl=en# Yoputube: https://www.youtube.com/playlist?list=PLkqQGGEN-8wdb-fFNUrlBrujl0w27nUNt Here are my key takeaways: Holistic Health Approach: Ali Gilbert emphasized the importance of understanding testosterone beyond its stereotypes. It's not just about muscles and sexual health; it's pivotal for brain function, energy, and overall quality of life. Integration of Fitness and Medicine: Ali's creation of the Silverback Summit demonstrates the value of bridging the gap between the fitness and medical communities, promoting collaboration for comprehensive men's health. Mindful Resilience: The discussion highlighted how optimizing health, including mental clarity and resilience, can amplify one's presence and impact in personal and professional spheres. A true boardroom athlete is built through consistent dedication to health. This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Feb 25, 2025 • 1h 5min
CM#7: Head Strong: The Science and Strategy Behind Concussion Recovery
Today, we're diving deep into an important topic in the world of sports and beyond – concussions. Our host, Chris Duffin, welcomes guest Anthony Castor to explore the complexities of traumatic brain injuries, often caused by sudden jolts or blows to the head. The episode uncovers the neurological changes that these injuries entail, discussing both their short-term symptoms, like headaches and confusion, and long-term effects, including cognitive impairment and mood disorders. Moreover, Chris and Anthony delve into a variety of healing protocols, emphasizing the pivotal role of peptides in recovery. Whether you're an athlete or someone curious about brain health, this episode offers vital insights on tackling brain injuries and fostering resilience. Tune in and learn about strategies to not only manage but also prevent the implications of concussions. 🎧 Missed the episode? Here are 3 key takeaways: Neuroprotection with Peptides: Peptides like BPC157 and TB4 play a crucial role in tissue regeneration and inflammation reduction, providing a neuroprotective shield during recovery. Brain Health Supplements: Incorporating omega-3s and phosphatidylcholine can fortify cell membranes and support acetylcholine production, key for memory and cognitive stability. Synergistic Therapies: Techniques like red light therapy and hyperbaric oxygen therapy optimize mitochondrial function and enhance blood flow, offering profound impacts for long-term brain health. Catch the full episode for a richer understanding of these powerful strategies to safeguard your most valuable asset—your brain! This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Feb 18, 2025 • 1h 14min
#26: Ketones Unlocked: The Science, Benefits, and Future of Nature's Superfuel with Frank Llosa
"Ketones Unlocked." In this episode, join host Chris Duffin as he delves into the fascinating world of ketones and their impact on metabolic health and performance optimization. Joined by guest experts Frank Llosa, founder and CEO of Ketone Aid, and Dr. Mike Debord, along with co-host Anthony Castor, they explore the biochemical magic of exogenous ketones in redefining energy, endurance, and mental clarity. Whether you're aiming for peak athletic performance, battling everyday brain fog, or seeking clarity in a chaotic world, this episode offers actionable insights into integrating these super fuels into your life. Get ready to redefine your relationship with energy and performance as the conversation unlocks the science and transformative potential of ketones. Episode Highlights: Unlocking Energy and Clarity with Ketones: Join us as Chris Duffin and guests explore the biochemistry behind ketones, focusing on how these compounds redefine energy, endurance, and mental clarity. Frank Llosa, CEO of Ketone Aid, shares his expert insights on the power of exogenous ketones and their role in everyday life. Breaking Down the Science: Frank Llosa and Rahul Desai discuss what ketones are, how they function in the body, and the difference between endogenous and exogenous ketones. Learn how fasting and dietary adjustments can influence ketone production and the powerful benefits they bring. Beyond the Basics – Exploring Applications: Discover how ketones can be integrated into various lifestyle practices, from sports performance to cognitive enhancement and even aiding in overcoming substance dependency. Tips for Integrating Ketones into Your Life: Frank Llosa provides actionable strategies to effectively utilize ketones for diverse needs, whether that's preparing for a big race, enhancing recovery, or improving sleep. The Future of Ketones in Longevity and Health: The episode also touches upon the growing research surrounding ketones' role in longevity and maintaining cognitive function. This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Feb 14, 2025 • 25min
BFR Discussion Highlights! What is it all about?
This is a 24 minute snippit from my incredible conversation with Dr. Mike on BFR training. Check out the full episode here, https://youtu.be/BY2PafMWwBA Dr. Mike is a leading expert in blood flow restriction (BFR) training, a method that's changing the game for athletes, rehab patients, and fitness enthusiasts alike. From understanding the origins of BFR and its scientific underpinnings to real-world applications and personalized training protocols. This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Feb 5, 2025 • 1h 21min
#25: Revolutionizing Recovery: Dr. Rahul Desai on the Power of Light and Regeneration
Chris Duffin welcomes Rahul Desai, a renowned expert in regenerative orthopedic medicine and founder of Restore PDX and Redvive. Join us as we explore Rahul's journey from radiology to regenerative medicine, where his innovative techniques in tissue regeneration have set new standards in the field. Delving into the world of red light therapy, or photobiomodulation, Rahul shares fascinating insights into its impact on enhancing tissue recovery, reducing inflammation, and accelerating healing. Discover how precision diagnosis and cutting-edge therapeutic approaches are helping people overcome musculoskeletal challenges and unlock their true strength. Rahul Desai always had a fascination with the human body and initially aspired to specialize in orthopedics and sports medicine. His journey through medical school led him to St. Jude's Children's Hospital, where he discovered a profound interest in radiology, specifically musculoskeletal interventional radiology. Captivated by the precision and technology involved, he became adept at using imaging techniques like MRIs, CAT scans, live X-rays, and ultrasounds to guide procedures such as steroid injections, biopsies, and device placements. Rahul's career path, marked by serendipity and passion, showcases his dedication to advancing medical interventions through innovative imaging techniques. Check out Restore PDX: https://www.restorepdx.com/energy-based-medicine/ Regenerative Medicine Techniques Explanation of PRP and its effects on tissue healing. Introduction to cell therapy using bone marrow and fat for stem cells. Presentation of case studies involving regenerative medicine, including recovery from tendon and ligament injuries. Photobiomodulation (Red Light Therapy) Introduction of photobiomodulation as a complementary therapy. Benefits observed in terms of sleep improvement, HRV (Heart Rate Variability), and stem cell activation. Discussion of studies highlighting photobiomodulation's impact on stem cell circulation and cellular health. This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Jan 28, 2025 • 1h 5min
#24: Beyond the Burn: The Science of Blood Flow Restriction with Dr. Mike DeBord
Today we're diving into revolutionary fitness and rehabilitation techniques with Dr. Mike Debord, a pioneer behind B3 Sciences. Dr. Mike is a leading expert in blood flow restriction (BFR) training, a method that's changing the game for athletes, rehab patients, and fitness enthusiasts alike. From understanding the origins of BFR and its scientific underpinnings to real-world applications and personalized training protocols, we cover it all. This episode is packed with insights on how BFR can amplify muscle growth, expedite recovery, and even improve cardiovascular health. Tune in to learn about the practicalities, safety considerations, and potential life-changing benefits of incorporating BFR into your fitness regimen. Whether you're an elite athlete or just starting out, you won't want to miss this detailed conversation on optimizing your health and performance. 🎧 Tune in to discover: Origins of BFR: ⏳ Learn how BFR evolved from Dr. Sato's 1960s discovery in Japan to an essential tool many top athletes swear by today. Physiological Insights: 🏋️♂️ Uncover how BFR stimulates growth hormone, increases muscle fiber recruitment, and enhances neurological functions – leading to both strength and endurance benefits. Safety & Protocols: 🔒 Dr. Mike shares practical advice on the safe use of BFR, including how to adjust pressure and integrate BFR in various training protocols, ensuring maximum benefits while minimizing risks. This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com Contents: 00:00 BFR Technique Gains Global Popularity 06:27 BFR Mechanisms and Benefits Overview 15:06 Pre-Training BFR Workout Strategy 16:50 Pre-Competition BFR Boosts Performance 21:55 Intuitive Recovery and Strength Gains 28:30 "Managing Hypoxia with BFR Bands" 32:50 BFR Bands Enhance Endurance Training 37:58 "Anabolic Healing vs. Stress Mode" 44:16 Innovative Tourniquet Design Risks 48:42 Mitochondria and Muscle Burn Mechanism 56:10 BFR Workout Frequency Guidelines 01:02:37 Balanced Fitness for Longevity 01:04:01 Live BFR Fitness Platform Launch Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Jan 17, 2025 • 23min
CM#6: Cancer, Metformin, and the mTOR Pathway: Separating Fact from Fiction in Insulin Mimetic Therapy
Chris Duffin sits down with expert guest Anthony Castor to delve deep into the fascinating world of insulin mimetics, glucose metabolism, and their implications for overall health and aging. The conversation kicks off with an examination of metformin's widespread use in diabetes management and its controversial potential benefits in cancer prevention, as highlighted in a recent study that casts doubt on its anti-cancer efficacy. Anthony and Chris explore the intricacies of balancing key cellular pathways—AMPK and mTOR—and their roles in muscle metabolism and aging. They discuss how the AMPK pathway acts as a guardian of energy preservation in the cell, especially under conditions of low nutrient availability, while mTOR is pivotal for muscle protein synthesis and energy expenditure. They also touch upon the impact of gut microbiome shifts on insulin sensitivity and how products like berberine and metformin can influence these pathways, sometimes to the detriment of muscle mass gain. Metformin and Gut Microbiome Positive impacts of metformin on gut microbiome GI disturbances related to insulin mimetics Role of AMPK signaling in energy preservation and muscle protein synthesis Benefits of products like berberine, banaba leaf extract, and alpha lipoic acid Hormonal support and muscle mass considerations This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation. Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Jan 3, 2025 • 37min
Atlas Power Shrugged - Old Time Lifts for Gains
Atlas Power Shrugged, a strength coach and author, combines classic lifting techniques with science to make strength training accessible. He emphasizes the importance of mental toughness and structured preparation in both fitness and business. Listeners will learn about unique lifts like the one-arm snatch and Arthur Saxon's bent press, as well as how to integrate old-time methods into modern routines for enhanced mobility. Atlas also shares insights on resilience and the balance of strength training, making it relevant for all fitness levels.

Dec 17, 2024 • 47min
NGT#3 LiftLab App - Harnesing Technology for Training
Chris Duffin is joined by Alex Miller, a dedicated innovator transforming the fitness tech landscape. They'll dive into the groundbreaking features of the Lift Lab app—a cutting-edge training tool designed to bring personalized coaching right to your phone. From sophisticated AI that analyzes your movement to a uniquely adaptable coaching system, the Lift Lab app is changing the game by focusing on simplicity and effectiveness. Alex Miller will share insights into the advanced pose estimation models, the importance of personalized stress management, and how the app leverages years of data to deliver hyper-personalized training. Chris and Alex will also discuss the thoughtful methodology behind data collection and the app's user-friendly approach, ensuring that complexity doesn't hinder your progress. Whether you're preparing for a competitive powerlifting meet or looking to enhance your everyday workouts, this episode explores how the Lift Lab app can help you achieve your fitness goals with precision and ease. Download the LiftLab app today and find the optimal balance between effort and recovery: https://www.liftlabapp.com This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin In this Episode, We Discuss: The Lift Lab App: Explore how the app leverages advanced AI, mobile technology, and data science to deliver a hyper-personalized training experience. Imagine having a "coach in your pocket" that tracks your movement and offers real-time feedback without the need for additional devices. Innovative Features: Understand the unique features of the Lift Lab app, such as AI pose estimation, joint position analysis, and velocity-based training (VBT), all designed to streamline your fitness journey and ensure you're always on the right track. Real-World Applications: Alex Miller shares how this technology can be applied across diverse activities like swimming, alpine skiing, ski hunting, and horseback riding. It's about making fitness adaptable to your lifestyle. Contents: 00:00 AI-driven, personalized coaching via Lift Lab app. 05:28 Systematizing coaching data with AI-enhanced tools. 08:36 Phone calculates weight, guides adjustments seamlessly. 12:41 App personalizes training program based on user data. 14:09 App estimates individual stress loading for deadlifts. 18:43 Using stress index maintains consistent training stress. 22:49 Analyzing training variance for abnormal stress levels. 24:29 Traditional deloads risk overtraining, potential injuries. 29:00 App helps diagnose and improve deadlift technique. 33:26 Developing app tracks recovery metrics and sensations. 34:21 App adjusts workouts based on elbow stress. 39:01 Oxygen delivery, critical power, sustainable output strategy. 40:48 Maintain power output, achieve 35 VO2 max. 43:56 Balancing simplicity and careful data collection. Join my FREE Education Platform & Community https://chrisduffin.com/start-here


