Architect of Resilience

On this special episode of the Architect of Resilience Podcast, host Chris Duffin welcomes back Dr. Rahul Desai, a regenerative musculoskeletal radiologist and expert in innovative therapies for joint and spine health. Originally recorded during a private member community session, this conversation dives deep into the cutting-edge world of red and near-infrared light therapy—otherwise known as photobiomodulation. Dr. Desai shares his extensive experience using platelet-rich plasma (PRP), bone marrow, and fat-derived treatments to help patients heal without surgery, and he unpacks the science and safety of red light therapy for tissue regeneration, pain relief, and overall wellness. The discussion is packed with direct audience questions, revealing practical insights on treatment timing, optimal dosing, systemic versus local effects, and the latest research on using light therapy for everything from injury recovery to anti-aging and sleep.   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by  @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @bearfootshoes : The Original Barefoot Lifting Shoe 🐻🦶🏼 Use code RESILIENCE for 10% off your order at https://www.bearfoot.store   Rahul Desai is a seasoned regenerative musculoskeletal radiologist and physician, with nearly two decades of experience since beginning his career in 2008. Specializing in non-surgical approaches, Dr. Desai combines his diagnostic radiology expertise with innovative regenerative therapies, using patients’ own platelets, bone marrow, and fat to facilitate healing. Here are my top 3 takeaways: Red Light Therapy for Both Injury and Wellness: Dr. Desai broke down how photobiomodulation helps tissues heal by stimulating stem cell activation, improving mitochondrial function, reducing inflammation, and even supporting healthy aging—even if you aren’t currently injured. Microdosing Matters: Instead of large, infrequent treatments, consistent, shorter daily exposures seem to offer maximized benefits for both local healing and systemic wellness. Dr. Desai personally uses red light therapy twice a day for sustained joint health and energy. Individualized, Layered Regeneration: Combining targeted regenerative therapies (like PRP, stem cell injections) with tools like red light, movement, and lifestyle changes creates better—and often visible—healing outcomes. Dr. Desai emphasized the importance of precision diagnosis and treatment for truly resilient recovery. Whether you're an athlete, healthcare professional, or just striving for better daily function, this conversation is loaded with actionable science and practical pearls.   Contents: 00:00 Regenerative Musculoskeletal Radiologist Expertise 05:57 "Photobiomodulation Safety and Risks" 07:48 Optimal LED Therapy Duration 10:50 Stem Cell Activation Techniques 16:03 Therapy Localization Protocols Inquiry 17:12 Rotator Cuff Therapy Considerations 20:20 Irradiation's Role in Tissue Healing 26:09 Circadian Rhythm Enhances Mitochondrial Efficiency 27:29 Evening Optical Pathways Enhance Sleep 31:27 Energy Routines and Sleep Impact 36:30 Inadequate Treatment Dosing Concerns 40:23 Enhancing Healing with Stem Cells 41:08 Red Mite's Pain Reduction Mechanism   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Today, we take an unforgettable journey into the frozen grounds of resilience with our guest, Stephen Kesting. Stephen is not only a Brazilian jiu-jitsu black belt and renowned martial arts educator but also an intrepid adventurer whose life story combines the thrill of wilderness survival with profound insights into personal strength and perseverance. In this episode, Stephen recounts his gripping survival journey through the subarctic wilderness, a story captured in his book "Perseverance: Life and Death in the Subarctic." We explore themes of mental toughness, the dichotomy between happiness and satisfaction, and the parallels between wilderness survival and tackling life's adversities.  Join us as we delve into the lessons learned from striking out into the wild, embracing adversity, and finding strength through endurance.   Key Takeaways: Embrace Self-Doubt: Recognizing self doubt as a natural part of challenging situations allows you to acknowledge and overcome it. It's not about denying it, but about seeing it for what it really is – a temporary visitor. Preparation is Key: Whether tackling major projects or surviving the wild, preparation is paramount. This includes research, planning, and acknowledging potential pitfalls while having contingency plans ready. Satisfaction Over Happiness: Success isn’t always about immediate happiness. It’s about the satisfaction of achieving long-term goals and overcoming obstacles, which can be a greater guide in life's journey.   Steven Kesting: https://www.grapplearts.com Youtube: https://www.youtube.com/user/StephanKesting   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Contents: 00:00 "Martial Arts Mentor: Stephen Kesting" 06:57 Embracing the Pit: A Journey 13:02 Wilderness Grief Processing Journey 23:03 Optimizing Health with Merrick Health 30:49 Business Continuity Planning Exercise 39:13 Training Strategy and Cardio Benefits 44:36 Alarming Blood Test Results 54:27 Cold Water Thermogenesis and Rehab Benefits 01:07:31 Self-Doubt and Injury Reflections 01:09:50 "Balancing Recovery and Minor Setbacks" 01:19:42 Blogged Journey Became a Book   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!  

In today’s episode, we are diving deep into the fascinating world of biohacking mitochondrial health for peak performance. Chris Duffin is joined by guest Anthony Castor as they explore groundbreaking compounds that can enhance cellular energy and optimize your body's energy systems for better performance, longevity, and overall well-being. From understanding the vital roles of mitochondrial fission and fusion to discovering cutting-edge compounds like SLU, PP332, and BAM15, this conversation is packed with insights that can revolutionize how you view your mitochondrial health.  Learn more and find the best way to source: https://chrisduffin.myshopify.com/blogs/chris-duffin-blog/bam15-the-ultimate-mitochondrial-uncoupler-for-fat-loss-energy-and-longevity   Exciting insights on biohacking cellular energy for peak performance from the latest episode of the Architect of Resilience Podcast! Chris Duffin and Anthony Castor delve into mitochondrial health and how to optimize it for better performance, longevity, and wellbeing. 🎧 Here's what you'll discover: Mitochondrial Health Principles: Understand the roles of mitochondrial fission, fusion, and their impact on cellular health. These processes are key for maintaining mitochondrial quality, production, and efficient energy metabolism. Game-Changing Compounds: Explore cutting-edge compounds like BAM15 and Urolithin A. While BAM15 is a potent mitochondrial uncoupler that boosts fat burning and metabolic flexibility, Urolithin A focuses on mitophagy, ensuring efficient recycling of damaged mitochondria. Strategic Usage for Maximum Impact: Learn the importance of using these compounds strategically. Combinations like SLU PP332 on training days and BAM15 on off days can efficiently manage energy production and recovery. Are you ready to revolutionize your approach to health and performance? Check out the full episode to dive deeper into these insights! #MitochondrialHealth #Biohacking #PerformanceOptimization #PodcastTakeaways #HealthAndWellness   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!  

We explore the nuances of men's health with renowned fitness professional Ali Gilbert. Specializing in hormonal optimization and strength training, Ali shares insights from over two decades of experience in transforming men's lives. As she discusses her journey into the niche of men's health, Ali highlights the critical role of testosterone therapy and its often overlooked benefits beyond muscles and sexual health. The podcast delves into the challenges and misconceptions surrounding testosterone therapy, coupled with insights on how hormonal health significantly impacts mental clarity, energy, and resilience. Ali also discusses the importance of optimizing one's health for peak performance, especially for entrepreneurs and professionals aiming to excel. Additionally, we touch upon her groundbreaking Silverback Summit, an event uniting medical and fitness communities to address men's health holistically. Join us for a deep dive into men's health, resilience, and what it truly means to develop strength inside and outside the gym.   Check out Ali: Website: https://ali-gilbert.com IG: https://www.instagram.com/thealigilbert/?hl=en# Yoputube: https://www.youtube.com/playlist?list=PLkqQGGEN-8wdb-fFNUrlBrujl0w27nUNt   Here are my key takeaways: Holistic Health Approach: Ali Gilbert emphasized the importance of understanding testosterone beyond its stereotypes. It's not just about muscles and sexual health; it's pivotal for brain function, energy, and overall quality of life. Integration of Fitness and Medicine: Ali's creation of the Silverback Summit demonstrates the value of bridging the gap between the fitness and medical communities, promoting collaboration for comprehensive men's health. Mindful Resilience: The discussion highlighted how optimizing health, including mental clarity and resilience, can amplify one's presence and impact in personal and professional spheres. A true boardroom athlete is built through consistent dedication to health.   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!  

Today, we're diving deep into an important topic in the world of sports and beyond – concussions. Our host, Chris Duffin, welcomes guest Anthony Castor to explore the complexities of traumatic brain injuries, often caused by sudden jolts or blows to the head. The episode uncovers the neurological changes that these injuries entail, discussing both their short-term symptoms, like headaches and confusion, and long-term effects, including cognitive impairment and mood disorders. Moreover, Chris and Anthony delve into a variety of healing protocols, emphasizing the pivotal role of peptides in recovery. Whether you're an athlete or someone curious about brain health, this episode offers vital insights on tackling brain injuries and fostering resilience. Tune in and learn about strategies to not only manage but also prevent the implications of concussions.   🎧 Missed the episode? Here are 3 key takeaways: Neuroprotection with Peptides: Peptides like BPC157 and TB4 play a crucial role in tissue regeneration and inflammation reduction, providing a neuroprotective shield during recovery. Brain Health Supplements: Incorporating omega-3s and phosphatidylcholine can fortify cell membranes and support acetylcholine production, key for memory and cognitive stability. Synergistic Therapies: Techniques like red light therapy and hyperbaric oxygen therapy optimize mitochondrial function and enhance blood flow, offering profound impacts for long-term brain health. Catch the full episode for a richer understanding of these powerful strategies to safeguard your most valuable asset—your brain!   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!    

"Ketones Unlocked." In this episode, join host Chris Duffin as he delves into the fascinating world of ketones and their impact on metabolic health and performance optimization. Joined by guest experts Frank Llosa, founder and CEO of Ketone Aid, and Dr. Mike Debord, along with co-host Anthony Castor, they explore the biochemical magic of exogenous ketones in redefining energy, endurance, and mental clarity. Whether you're aiming for peak athletic performance, battling everyday brain fog, or seeking clarity in a chaotic world, this episode offers actionable insights into integrating these super fuels into your life. Get ready to redefine your relationship with energy and performance as the conversation unlocks the science and transformative potential of ketones.   Episode Highlights: Unlocking Energy and Clarity with Ketones: Join us as Chris Duffin and guests explore the biochemistry behind ketones, focusing on how these compounds redefine energy, endurance, and mental clarity. Frank Llosa, CEO of Ketone Aid, shares his expert insights on the power of exogenous ketones and their role in everyday life. Breaking Down the Science: Frank Llosa and Rahul Desai discuss what ketones are, how they function in the body, and the difference between endogenous and exogenous ketones. Learn how fasting and dietary adjustments can influence ketone production and the powerful benefits they bring. Beyond the Basics – Exploring Applications: Discover how ketones can be integrated into various lifestyle practices, from sports performance to cognitive enhancement and even aiding in overcoming substance dependency. Tips for Integrating Ketones into Your Life: Frank Llosa provides actionable strategies to effectively utilize ketones for diverse needs, whether that's preparing for a big race, enhancing recovery, or improving sleep. The Future of Ketones in Longevity and Health: The episode also touches upon the growing research surrounding ketones' role in longevity and maintaining cognitive function.   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by: @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

This is a 24 minute snippit from my incredible conversation with Dr. Mike on BFR training. Check out the full episode here, https://youtu.be/BY2PafMWwBA Dr. Mike is a leading expert in blood flow restriction (BFR) training, a method that's changing the game for athletes, rehab patients, and fitness enthusiasts alike. From understanding the origins of BFR and its scientific underpinnings to real-world applications and personalized training protocols.   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Chris Duffin welcomes Rahul Desai, a renowned expert in regenerative orthopedic medicine and founder of Restore PDX and Redvive. Join us as we explore Rahul's journey from radiology to regenerative medicine, where his innovative techniques in tissue regeneration have set new standards in the field. Delving into the world of red light therapy, or photobiomodulation, Rahul shares fascinating insights into its impact on enhancing tissue recovery, reducing inflammation, and accelerating healing. Discover how precision diagnosis and cutting-edge therapeutic approaches are helping people overcome musculoskeletal challenges and unlock their true strength. Rahul Desai always had a fascination with the human body and initially aspired to specialize in orthopedics and sports medicine. His journey through medical school led him to St. Jude's Children's Hospital, where he discovered a profound interest in radiology, specifically musculoskeletal interventional radiology. Captivated by the precision and technology involved, he became adept at using imaging techniques like MRIs, CAT scans, live X-rays, and ultrasounds to guide procedures such as steroid injections, biopsies, and device placements. Rahul’s career path, marked by serendipity and passion, showcases his dedication to advancing medical interventions through innovative imaging techniques.   Check out Restore PDX: https://www.restorepdx.com/energy-based-medicine/   Regenerative Medicine Techniques Explanation of PRP and its effects on tissue healing. Introduction to cell therapy using bone marrow and fat for stem cells. Presentation of case studies involving regenerative medicine, including recovery from tendon and ligament injuries. Photobiomodulation (Red Light Therapy) Introduction of photobiomodulation as a complementary therapy. Benefits observed in terms of sleep improvement, HRV (Heart Rate Variability), and stem cell activation. Discussion of studies highlighting photobiomodulation's impact on stem cell circulation and cellular health.   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by  @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!

Today we’re diving into revolutionary fitness and rehabilitation techniques with Dr. Mike Debord, a pioneer behind B3 Sciences. Dr. Mike is a leading expert in blood flow restriction (BFR) training, a method that's changing the game for athletes, rehab patients, and fitness enthusiasts alike. From understanding the origins of BFR and its scientific underpinnings to real-world applications and personalized training protocols, we cover it all. This episode is packed with insights on how BFR can amplify muscle growth, expedite recovery, and even improve cardiovascular health. Tune in to learn about the practicalities, safety considerations, and potential life-changing benefits of incorporating BFR into your fitness regimen. Whether you're an elite athlete or just starting out, you won't want to miss this detailed conversation on optimizing your health and performance.   🎧 Tune in to discover: Origins of BFR: ⏳ Learn how BFR evolved from Dr. Sato’s 1960s discovery in Japan to an essential tool many top athletes swear by today. Physiological Insights: 🏋️‍♂️ Uncover how BFR stimulates growth hormone, increases muscle fiber recruitment, and enhances neurological functions – leading to both strength and endurance benefits. Safety & Protocols: 🔒 Dr. Mike shares practical advice on the safe use of BFR, including how to adjust pressure and integrate BFR in various training protocols, ensuring maximum benefits while minimizing risks.   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by  @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Contents: 00:00 BFR Technique Gains Global Popularity 06:27 BFR Mechanisms and Benefits Overview 15:06 Pre-Training BFR Workout Strategy 16:50 Pre-Competition BFR Boosts Performance 21:55 Intuitive Recovery and Strength Gains 28:30 "Managing Hypoxia with BFR Bands" 32:50 BFR Bands Enhance Endurance Training 37:58 "Anabolic Healing vs. Stress Mode" 44:16 Innovative Tourniquet Design Risks 48:42 Mitochondria and Muscle Burn Mechanism 56:10 BFR Workout Frequency Guidelines 01:02:37 Balanced Fitness for Longevity 01:04:01 Live BFR Fitness Platform Launch   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!  

Chris Duffin sits down with expert guest Anthony Castor to delve deep into the fascinating world of insulin mimetics, glucose metabolism, and their implications for overall health and aging. The conversation kicks off with an examination of metformin's widespread use in diabetes management and its controversial potential benefits in cancer prevention, as highlighted in a recent study that casts doubt on its anti-cancer efficacy. Anthony and Chris explore the intricacies of balancing key cellular pathways—AMPK and mTOR—and their roles in muscle metabolism and aging. They discuss how the AMPK pathway acts as a guardian of energy preservation in the cell, especially under conditions of low nutrient availability, while mTOR is pivotal for muscle protein synthesis and energy expenditure. They also touch upon the impact of gut microbiome shifts on insulin sensitivity and how products like berberine and metformin can influence these pathways, sometimes to the detriment of muscle mass gain. Metformin and Gut Microbiome Positive impacts of metformin on gut microbiome GI disturbances related to insulin mimetics Role of AMPK signaling in energy preservation and muscle protein synthesis Benefits of products like berberine, banaba leaf extract, and alpha lipoic acid Hormonal support and muscle mass considerations   This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by  @marekhealth : Performance. Longevity. Optimization. 🔬 Use code RESILIENCE for 10% off your first bloodwork at https://marekhealth.com/chrisduffin @naboso_technology : The Foundation of Movement. 🦶🏼Use Code RESILIENCE for 20% off your first order at https://www.naboso.com   Learn & Connect at https://chrisduffin.com/ • SHOP: Explore my books and products in the store. • EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.  Plus, dive into a wealth of articles on supplements, peptides, and training. • CONNECT: Join my FREE community to engage with like-minded individuals. Don't miss out on these valuable resources—visit now and take your performance to the next evolution… the Endless Evolution!