Everyday Wellness: Midlife Hormones, Health, and Science for Women 35+

Today, I am delighted to reconnect with Dr. Sara Gottfried, a board-certified physician practicing evidence-based integrative precision and functional medicine. (She last joined me for Episode 211.)Dr. Gottfried graduated from Harvard and MIT. She is a Clinical Assistant Professor in the Department of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University and the Director of Precision Medicine at the Marcus Institute of Integrative Health. She is also the author of four New York Times best-selling books, including her recent publication, The Autoimmune Cure. In our discussion today, we discuss the interrelationship between trauma and autoimmunity, highlighting its prevalence, particularly among women. We dive into the impact of trauma, explaining its correlation with autoimmune conditions and demystifying the role of the PINE network (the Psycho Immune Neuro Endocrine system). We explore triggers for perimenopause and menopause, gender differences specific to the changes in immunity and vulnerability in women, the consequences of burnout in various professions, the shortcomings of conventional allopathic methods in addressing mental health and trauma, and immunomodulation, including vitamins, polyphenols, low-dose Naltrexone, and somatic-based therapies. With Dr. Gottfried’s invaluable insights into crucial health topics, this episode is a must-listen. Stay tuned for more!IN THIS EPISODE YOU WILL LEARN: How the traumas we experience as children could make us more susceptible to autoimmune conditions later in life How trauma impacts our immune, neurological, and endocrine systems Addressing trauma through gut health, heart rate variability, and hormone balance How the metabolic and immune system changes triggered during perimenopause and menopause can make women more susceptible to autoimmune issues  How men in combat and women with sexual assault show similar trauma responses  How childhood trauma can shape our direction in life The potential benefits of alternative therapies like LSD, MDMA, and Ayahuasca How measuring gut health can provide valuable insights for treatment options Using low-dose Naltrexone for sleep and immune system modulation The potential of somatic therapies and breathwork for stilling the autonomic nervous system and promoting body awareness Bio: Dr. Sara Gottfried:Sara Szal Gottfried, MD, is a physician, researcher, author, and educator. She graduated from Harvard Medical School and MIT and completed a residency at UCSF, but is more likely to prescribe a CGM and personalized nutrition plan than the latest pharmaceutical. Dr. Gottfried is a global keynote speaker and the author of four New York Times bestselling books about hormones, nutrition, and health. Her latest book is called THE AUTOIMMUNE CURE (March 2024). She is a Clinical Assistant Professor in the Dept. of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University and Director of Precision Medicine at the Marcus Institute of Integrative Health. She takes care of executives and professional athletes. Her focus is on the interface of mental and physical health, N-of-1 trial design, personalized molecular profiling, use of wearables, and how to leverage these tools to improve health outcomes. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Sara Gottfried On her website    On Instagram Dr. Gottfried’s new book, The Autoimmune Cure, is available from most bookstores, including Amazon and Barnes and Noble. Previous Episode MentionedEp. 211 – Addressing the Root Cause of Hormonal Imbalances with Dr. Sara Gottfried

I am delighted and honored today to interview Dr. Lisa Mosconi. She is an Associate Professor of Neuroscience in neurology and radiology at Cornell Medicine and Director of the Women's BRAIN Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine, New York Presbyterian Hospital. She is also a globally acclaimed neuroscientist with a Ph.D. in neuroscience and nuclear medicine and the author of the New York Times bestseller The XX Brain and, more recently, The Menopause Brain.In our conversation, we discuss how women’s brains change during perimenopause and menopause, looking at the significance of puberty, pregnancy, and perimenopause, as well as the lack of medical research on women and medical gaslighting. We explore the concept of bikini medicine and its misconceptions regarding women's health and hormones alongside the crucial roles of hormones like estradiol, progesterone, and testosterone in our neuroendocrine system. Dr. Mosconi also provides insights into evolving menopausal treatments, including lifestyle interventions. Dr. Mosconi is an esteemed figure in neuroscience and a prominent voice in women's health. I am confident you will gain valuable insights and perspectives from my discussion with her today.IN THIS EPISODE YOU WILL LEARN: How women's brains change during perimenopause and menopause How the lack of information for young girls can lead to medical gaslighting and confusion during perimenopause Dr. Mosconi explains how a simple sugar is used as a tracer to track glucose metabolism in the brain during perimenopause Why brain changes during menopause may lead to mental fatigue and brain fog How the lack of training and research on menopause in medical residency programs leads to a poor understanding among clinicians Why women need to consider their brain and metabolic health during perimenopause Why estrogen is essential after menopause The benefits of HRT for menopausal women How stress impacts hormone production Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Lisa Mosconi On her website On Instagram The Menopause Brain will be released March 12th, 2024.

Today's episode is a true gem! I am thrilled to introduce Craig Siegel, the Wall Street Journal and USA Today Best Selling Author of The Reinvention Formula. Craig is recognized globally as a keynote speaker, TEDx speaker, and host of the CLS Experience Podcast, where he has conversed with some of the most influential figures in the world. Having the privilege of being a guest on his show in 2023, I am delighted to have Craig joining me today to share his remarkable insights and discuss his inspiring journey. In our conversation today, Craig shares how the pandemic became a catalyst for his evolution, which he refers to as his global awakening. We explore the importance of setting audacious goals and the transformative power of vulnerability. We also look into neuro-linguistic programming and clarify how it can cultivate confidence and reframe your mindset. We also discuss the role of adversity, ego dynamics, and why service implies love, and creates a lasting legacy. This conversation will infuse your year with invaluable wisdom, and I look forward to additional collaborations with Craig going forward. Stay tuned for more!IN THIS EPISODE YOU WILL LEARN: How the pandemic restructured Craig’s life and helped him redefine himself Craig shares his journey of embracing vulnerability and authenticity The benefits of having bold, fearless, and audacious goals How being willing to look silly or make mistakes can lead to success How mindset influences growth, both personally and professionally How neuro-linguistics can reprogram belief systems The power of choice and imagination for creating positive change Why it is essential to align your decisions with your personal and professional goals rather than being driven by ego Why building a community based on mutual support and collaboration is even more important than building an audience How authentic conversations can lead to inspired action Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Connect with Craig Siegel On his website Instagram The CLS Experience Podcast Craig's BookThe Reinvention Formula is available on Amazon and most anywhere books are sold.For free inspirational messages throughout the week, text Craig at 917-634-3796 using the code CYNTHIA and share your favorite nugget from today’s conversation.

Learn about the safety and efficacy of creatine, its impact on muscle mass and cognition, and the benefits of combining it with protein. Explore the interplay between creatine and caffeine, hydration strategies, and the importance of exercise for bone health. Discover the unique benefits of creatine for post-menopausal women, cognitive function, and metabolic health.

Today, I have the privilege of engaging with Kashif Khan.Kashif is the author of The DNA Way. He is also a two-time TEDx speaker, a celebrity longevity coach, and Founder of The DNA Company, an innovative company at the forefront of personalized medicine that has leveraged unique insights into the human genome. In our conversation today, we dive into the impact of our current healthcare system and share daily practices to help men and women enhance their longevity. We discuss the genome, considerations for bio-individuality and genetics, and how mood and behavior impact our overall well-being. Kashif also addresses some issues women face in midlife, including sleep problems, weight loss resistance, and bone health. I am sure anyone seeking a deeper understanding of these matters will find our discussion significant and most valuable.IN THIS EPISODE YOU WILL LEARN: How the focus of our current healthcare system is on symptom management, not prevention The fundamental principles of the 2018 Harvard study on five practices that every male and female can do to live longer Kashif explains how his company created a tool to make genetic testing more accessible and personalized  Why personalization in healthcare is so important How dopamine pathways affect the perception of pleasure and reward The symptoms of serotonin dysregulation Sleep disruptions and circadian rhythm in perimenopause and menopause How circadian rhythm disruptions can lead to sleep problems How our emotional intelligence impacts our ability to connect and empathize with others How broken detox pathways can lead to inflammation and disease How hormone dominance affects menopause, weight loss, and overall health Bio:Kashif Khan is the author of The DNA Way, a two-time TedX Speaker, Celebrity longevity coach, and Founder of The DNA Company, where personalized medicine is being pioneered through unique insights into the human genome.Growing up in Vancouver, Canada in an immigrant household, Kashif developed an industrious entrepreneurial spirit from a young age. Before his tenure at the DNA Company, Kashif advised several high-growth start-ups in a variety of industries.As Kashif dove into the field of functional genomics as the Founder of The DNA Company, it was revealed that his neural wiring was genetically designed to be entrepreneurial. However, his genes also revealed a particular sensitivity to pollutants.Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Kashif Khan On Instagram On his website   Go to Kashif’s special landing page   The DNA Company

Today, I have the privilege of connecting with Dr. Nicole LePera, the Holistic Psychologist. Dr. LePera did her clinical psychology training at Cornell University. She has touched the lives of countless individuals seeking growth and transformation through her popular Instagram account and has written several self-help books, including How to Do the Work and How to Be the Love You Seek. In our discussion today, we dive into the current impact of our childhood experiences, exploring crises of faith, the dark night of the soul, inner child archetypes, and shame. Dr. LePera sheds light on the dynamics of dysfunctional patterns, triggers, and regression while also examining the role of generational and systemic beliefs, trauma, and the emerging science of heart-brain coherence and heart rate variability, sharing practical tips for cultivating presence in our bodies to assist us in processing our emotions.Dr. LePera's work has been profoundly instrumental in my personal development journey, and I know you will find our conversation enlightening and enriching. IN THIS EPISODE YOU WILL LEARN: How the subconscious mind determines our habits and relationships Dr LePera explains the concept of the dark night of the soul The importance of examining your conditioned behaviors and reconnecting with your true identity  How inner child archetypes impact behavior Why is self-development essential? How our past experiences shape the way we perceive and interpret current events The benefit of embodiment practices for developing emotional tolerance How childhood trauma impacts physical and mental health The impact of intergenerational trauma on mental health How to achieve heart coherence Dr. LePera shares mindfulness practices for stress management and self-awareness Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Nicole LePera On her website How to Be The Love You Seek  On Instagram, YouTube, TikTok, and X

Dr. Sue Varma, a psychiatrist, discusses the impact of shared experiences like 9/11 and the pandemic, practical optimism, self-care, and self-reliance. Topics include optimism inheritability, women's milestones, purpose, compassion, processing emotions, perfectionism, trauma, ACE scores, autoimmunity, mindfulness, and meditation.

Dr. Thomas Dayspring discusses fundamentals of lipids and cholesterol, including classifications, physiology, and transportation. He explains the role of various lipoproteins in assessing cardiovascular risk and shares insights on lab values. Detailed discussion on lipid biology and transport, triglycerides' impact on calculated LDL cholesterol, and the importance of monitoring triglyceride levels for metabolic health.

I am delighted to reconnect with Dr. Steven Gundry today. He last joined me for episode 236. Dr. Gundry is one of the world's leading cardiothoracic surgeons and a nutrition pioneer. He hosts the highly acclaimed Dr. Gundry Podcast, on which I was honored to be a featured guest. He is the Founder and Director of the International Heart and Lung Institute Center for Restorative Medicine and the author of several New York Times bestselling books, including his most recent, Gut Check. In our conversation, we dive into gut diversity, exploring the interrelationship between specific parasitic organisms like toxoplasmosis and behavior. We share information on mitochondrial DNA and polyphenols and uncover the synergistic relationships they share with our gut microbiome. We also get into Resveratrol and Urolithin A and discuss pre-, pro-, and post-biotics, the impact of leaky gut, glyphosate, statin therapy, and Dr. Gundry's new Gut Check program. I am honored to facilitate this insightful dialogue with Dr. Steven Gundry and feel confident you will find it as engaging as I did while recording.IN THIS EPISODE YOU WILL LEARN: Why should your spouse clean the cat litter tray if you are pregnant? The synergistic relationship that exists between the gut microbiome, mitochondrial DNA, and polyphenols How resveratrol in red wine activates mitochondrial DNA repair compounds Why a diverse microbiome is the key to longevity  How do fermented foods improve gut health? How a leaky gut impacts bone health What bacterial translocation can lead to in men and women How does glyphosate affect our health? How gut sealing can reverse a leaky gut and autoimmune diseases Dr. Gundry explains how statins affect the gut microbiome Bio: Steven R. Gundry, MD, is the founder and director of the International Heart and Lung Institute in Palm Springs, California, and the Center for Restorative Medicine in Palm Springs and Santa Barbara. After a distinguished surgical career as a professor and chairman of cardiothoracic surgery at Loma Linda University, Dr. Gundry changed his focus to curing modern diseases via dietary changes. He is the author of New York Times bestsellers The Plant Paradox, The Plant Paradox Cookbook, The Plant Paradox Quick & Easy, and The Longevity Paradox, along with national bestsellers The Plant Paradox Family Cookbook, The Energy Paradox, Dr. Gundry’s Diet Evolution, and Unlocking the Keto Code, and more than 300 articles published in peer-reviewed journals on using diet and supplements to eliminate heart disease, diabetes, autoimmune disease, and multiple other diseases. He is the host of the weekly Dr Gundry Podcast and founder of wellness brand, Gundry MD. Dr. Gundry lives with his wife, Penny, and their dogs in Palm Springs and Montecito, CaliforniaAbout GUT CHECK:Unleash the Power of Your Microbiome to Reverse Disease and Transform Your Mental, Physical, and Emotional HealthBy Steven R. Gundry, MDIn the latest addition to his New York Times bestselling Plant Paradox series, GUT CHECK: Unleash the Power of Your Microbiome to Reverse Disease and Transform Your Mental, Physical, and Emotional Health (Harper Wave, January 9, 2024; ISBN: 978-0062911773; $32.00; 352 pages), Dr. Steven Gundry offers a definitive guide to the gut biome and its control over its home – us! Revealing the unimaginably complex and intelligent ecosystem controlling our health, Gut Check teaches us how to heal our gut to prevent and reverse every type of disease.Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Steven Gundry On his website or Gundry MD Gundry Health.Com The Dr. Gundry Podcast on YouTube Ep. 236 Keto Code: Unlocking Mitochondrial Health with Dr. Steven Gundry

I am delighted to reconnect with Esther Blum today. She joined me once before for Episode 264, one of the most popular podcast episodes for 2023. Esther is the bestselling author of many books, including See You Later Ovulator. She is a registered dietitian with a thriving virtual practice specializing in helping women balance their hormones, shed stubborn body fat, and address the root causes of their health issues.Today, Esther and I discuss the state of hormones in 2024. Our conversation covers lazy medicine advocacy, meno-washing, and meno-care, and we explore uncommon symptoms associated with perimenopause and menopause and methods for obtaining testing. Esther also shares her recommended supplements. You will love this engaging and insightful conversation with Esther Blum!IN THIS EPISODE YOU WILL LEARN: How safe is hormone replacement therapy? Why hormone testing and monitoring is essential  The importance of prioritizing romance and connection in a marriage The benefits of pelvic floor therapy How working with compounding pharmacies can reduce the cost of hormone replacement therapy How to work with doctors to address hormone imbalances Some uncommon symptoms of perimenopause and menopause How dietary changes and probiotics can improve focus and brain clarity  Hormone testing and menopause management  Esther recommends supplements for adrenal support during menopause Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Esther Blum On her website Instagram Get Esther’s 14-Day Metabolic Menopausal Meal Plan  Esther’s BooksEsther’s book, See Ya Later, Ovulator!, by Esther BlumCavewomen Don’t Get Fat, by Esther BlumEat, Drink, and Be Happy, by Esther BlumPrevious Episode featuring Esther BlumEp. 264 Peri/Menopause are a Natural Function of Aging: See you later, Ovulator!