Everyday Wellness: Midlife Hormones, Health, and Science for Women 35+

I am delighted to have Jessie Inchauspe, the Glucose Goddess, joining me on the podcast today!Metabolic health is my passion! It is a huge area of focus in my work, and Jessie is truly a gift in the space! She is a rising star author and biochemist with a clear and accessible way of explaining the science behind glucose metabolism. Jessie joins me today to discuss the impact of glucose metabolism and spikes. We dive into her background and how an accident created her pain-to-purpose story. We discuss the role of continuous glucose monitors and how glucose spikes impact our mitochondria, inflammation, and oxidative stress. We get into glycation and aging, how weight gain is a protective aspect of glucose spikes- or hyperglycemia, and the role of vinegar, movement, and fiber. We also talk about Jessie’s new book, her opinions on fasting, and so much more. I loved interviewing Jessie! Her enthusiasm is contagious, and it is easy to understand why she is such a beloved author in the health and wellness space!IN THIS EPISODE YOU WILL LEARN: Jessie shares how an accident led her to where she is today. How a continuous glucose monitor changed everything for Jessie. How Jessie came up with her simple principles to steady glucose levels. What is the purpose of glucose in the body? How do glucose spikes impact our mitochondria? Jessie shares a fascinating vinegar hack for reducing side effects and symptoms of glucose spikes. How being metabolically unhealthy impacts the aging process. The benefits of having savory breakfasts and eating vegetables first with every meal. Jessie talks about her new book, The Glucose Goddess Method. How gaining weight protects our bodies from the impact of glucose spikes. How walking or moving after meals balances blood sugar levels. Why is blood sugar so important? Connect with Cynthia ThurlowFollow on TwitterInstagramLinkedInCheck out Cynthia’s websiteConnect with Jessie InchauspeOn her website  On InstagramJessie’s booksThe Glucose Goddess MethodGlucose Revolution

I am thrilled to present the last class of our Lipid Masterclass series today with the esteemed Dr. Thomas Dayspring. Dr. Dayspring is board-certified in internal medicine and clinical lipidology and is a fellow of the American College of Physicians and the National Lipid Association. Today, we round things out by diving into medications for lipid abnormalities and discussing lipid physiology, with Dr. Dayspring shedding light on insulin resistance and statins and cautioning against statin use for those predisposed to diabetes or insulin resistance. He also explains why LDL particle size is not worth testing and discusses ways to identify specific laboratory abnormalities. Be sure to stay tuned for the AMA session to follow, where Dr. Dayspring will answer listeners’ questions. It has been a privilege engaging with Dr. Dayspring throughout this masterclass series. I know you will have learned a lot from it!IN THIS EPISODE YOU WILL LEARN:· The lack of research and consistency in addressing the needs of women in various stages of life· Dr. Dayspring discusses the use of bile acid sequestrants for lowering LDL cholesterol· Dr. Dayspring discusses the history of bile acid sequestrant use, explaining why their use is limited· How bempedoic acid and statins lower LDL cholesterol· Potential contraindications for bempedoic acid· The benefits and risks of using fibrates to reduce heart attacks· Dr. Dayspring explains why fibrates work best for genetic hypertriglyceridemia· Why reducing ApoB is essential for atherosclerosis patients, especially for high-risk patients· Dr. Dayspring explains why small LDL particles are dangerous· The ideal ApoB level for those who have no heart disease and are not diabetic Bio:Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia to serve as an educational director for a nonprofit cardiovascular foundation until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular/lipidology educator. Career-wise, he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women’s cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He received the 2011 National Lipid Association’s Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association, and he serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association.Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On Twitter (@DrLipid) On LinkedIn

I am delighted to reconnect with Dr. Anurag Singh today, the Chief Medical Officer at Timeline Nutrition. He joined me once before on Episode 268. I invited Dr. Singh back to discuss the latest research on GLP-1 agonists like Wegovy, Semaglutide, and Ozempic, which are gaining significant traction with projected sales exceeding $100 billion by 2030, potentially affecting 9% of the US population.In our conversation, we explore the contributors to our metabolic health crisis by looking at the research surrounding GLP-1 agonists, the physiology of GLP-1 peptides, and the influencing elements Dr. Singh refers to as the trifecta. We dive into the loss of muscle mass and strength, sarcopenia, and frailty associated with these drugs, and Dr. Singh shares his concerns about their impact on bone health, the gut microbiome, and their use in younger patients. We also get into lifestyle measures, mitochondrial health, hallmarks of aging, Akkermansia, and the importance of advocacy and patient empowerment. Today’s compelling and invaluable discussion with Dr. Anurag Singh highlights crucial insights into GLP-1 agonists and their broader health implications. I know it will provide significant value for our listeners.IN THIS EPISODE YOU WILL LEARN: Dr. Singh breaks down what GLP-1 agonist drugs are and how they work. How our modern-day lifestyles contribute to poor metabolic health The benefits and side-effects of using GLP-1 agonist treatments for improving metabolic health Why strength training is essential for preventing muscle loss and frailty in middle-aged women What are the potential long-term effects of SARMs on muscle mass and health? Why dietary counseling is essential for those taking GLP-1 agonist drugs The benefits of supplements for boosting mitochondrial health  Dr. Singh discusses a research study on combining lithium with GLP-1 agonists to improve the muscle quality of those with muscle-wasting conditions. Why akkermansia is essential for GLP production  Connect with Cynthia Thurlow   Follow on Twitter Instagram LinkedIn Check out Cynthia’s website  Submit your questions to support@cynthiathurlow.com Connect with Dr. Anurag Singh Timeline Mitopure Email Dr. Singh: asingh@amazentis.com  Previous Episode MentionedEp. 268: Understanding the Biology of Aging with Evolved Supplementation and Nutrition, featuring Dr. Anurag Singh

Today, I am delighted to reconnect with two previous guests, Dr. Darren Candow.Dr. Candow is a distinguished professor and an internationally renowned researcher on creatine monohydrate, nutrition, and physical activity who joined me before on Episode 301, where we spoke about creatine. We are doing an AMA session today, delving into various themes surrounding creatine, from debunking outdated RDA recommendations to exploring the synergies between strength training and creatine efficacy. We look into the cognitive benefits of creatine, exploring how it interacts with caffeine and its implications for bone health, hydration, anabolic resistance, and metabolic health. I trust you will find today's AMA session as enlightening and enriching as I did while recording it.IN THIS EPISODE YOU WILL LEARN: The safety and efficacy of creatine as a supplement How creatine increases muscle mass and reduces protein catabolism The benefits of combining creatine with protein  Is it better to take creatine before or after a workout? How creatine supplementation may improve brain performance and mental clarity Why exercise is essential for those who want to experience the benefits of creatine for maintaining their bone health The benefits of resistance-band workouts for post-menopausal women Are there any age-related limits for creatine supplementation? Bio: Dr. Darren CandowDr. Darren Candow, PhD, CSEP-CEP, is Professor and Director of the Aging Muscle and Bone Health Laboratory in the Faculty of Kinesiology and Health Studies at the University of Regina, Canada. The overall objectives of Dr. Candow’s research program are to develop effective lifestyle interventions involving nutrition (primarily creatine monohydrate) and physical activity (resistance training), which have practical and clinical relevance for improving musculoskeletal aging and reducing the risk of falls and fractures. Dr. Candow has published over 120 peer-refereed journal manuscripts, supervised over 20 MSc and PhD students, and received research funding from the Canadian Institutes of Health Research, Canada Foundation for Innovation, the Saskatchewan Health Research Foundation, the National Institute of Health, and the Nutricia Research Foundation. In addition, Dr. Candow serves on the editorial review boards for the Journal of the International Society of Sports Nutrition, Nutrients, and Frontiers.Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Darren CandowOn Instagram and Twitter (now X)Previous Episode Mentioned:Ep. 301 Creatine: The Best Supplement for Better Bones & Brain Health with Darren Candow, PhD, CSEP-CEP

I am honored to have Dr. Carolyn Dean joining me today.Dr. Dean is a medical doctor, naturopath, and best-selling author. She has dedicated more than 50 years to integrating the science of medicine with the gifts of nature to help her patients feel better, boost their energy, and take control of their health.Today, our conversation centers on The Flexner Report and its influence on modern medicine and the essential role of magnesium in over 80% of metabolic functions. We dive into why we are so magnesium-depleted and common disorders associated with low magnesium levels, and we explore the effects of magnesium on bone health and the microbiome and the synergistic properties of various forms of magnesium and other micronutrients. I am confident you will find today’s discussion with Dr. Carolyn Dean as enjoyable as it is enlightening.IN THIS EPISODE YOU WILL LEARN: How the Flexner Report has impacted allopathic, functional, and integrative approaches to health and wellness Why is magnesium so poorly understood? How to get your magnesium accurately tested How our modern-day lifestyles are contributing to the current magnesium deficiency epidemic  Dr. Dean shares her formula for hydration  The potential side effects of allopathic medications and how they impact our health Why magnesium is essential for aging women The relationship between magnesium and bone health The benefits of magnesium supplementation The complex relationship between magnesium and other minerals Dr. Dean talks about Magnesium Threonate and explains how all magnesium compounds can ultimately reach the brain. Bio:Carolyn Dean, MD, ND, is a medical doctor, naturopath, and best-selling author. She has spent 50+ years committed to applying the science of medicine and the gifts of nature to help people feel better, find more energy, and take control of their personal health. Dr. Dean follows the 2017 revision of 2004's best-selling book The Magnesium Miracle® with her newest revision Magnesium: The Missing Link to Total Health®.Connect with Cynthia Thurlow    Follow on Twitter Instagram LinkedIn   Check out Cynthia’s website  Submit your questions to support@cynthiathurlow.com Connect with Dr. Carolyn Dean On her website (For educational resources) RnA ReSet Store website Podcast  Magnesium: The Missing Link to Total Health by Dr. Carolyn Dean is available on Amazon Recommended PublicationMagnesium in the Central Nervous System

I am delighted to reconnect with Dr. Dave Rabin today. He last joined me for Episode 91 in April of 2020.Dr. Rabin is a board-certified psychiatrist and neuroscientist. He is the Co-founder and CMO at Apollo Neuroscience, the first scientifically validated wearable system to improve heart rate variability, focus, and relaxation, and helps attain meditative states. He is also Co-founder and Executive Director of the Board of Medicine and a psychedelic clinical researcher, currently evaluating the mechanism of psychedelic-assisted psychotherapy and treatment-resistant illness.Today, we examine the value of touch and sensory techniques, discussing the distinctions between sympathetic and parasympathetic vagal tone in the autonomic nervous system, changes in sex hormones during perimenopause and menopause, and how that impacts sympathetic dominance, the development of stress responses, and the concept of stress leading to personal growth. We explore the influence of the vagus nerve on systemic health, explaining what HRV is and how it can demonstrate bodily coherence, and we also dive into wearable technologies like Apollo, the disruption of psychedelic interventions, and the impact of trauma on physical and mental well-being. I am confident that you will find today’s engaging discussion with Dr. Dave Rabin eye-opening and enlightening.IN THIS EPISODE YOU WILL LEARN: How touch helps us connect, bond, and support our autonomic nervous system How finding balance between the parasympathetic and sympathetic nervous systems can help us manage stress and anxiety Techniques for quickly restoring balance to the nervous system Why women experience more anxiety, depression, and heart arrhythmias during perimenopause How breathing techniques can improve heart rate variability  The significance of HRV metrics for understanding physical and mental health How the Apollo device activates a healing response within the body The potential of MDMA and other psychedelics hold for trauma healing Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Dave Rabin On his website Apollo Instagram Twitter (X) The Psychedelic Report Podcast Your Brain Explained Podcast Previous Episode MentionedEp. 91 – How To Listen To Your Body and DE-STRESS During COVID-19 – with Dr. David Rabin

Dr. Tony Youn, a renowned plastic surgeon, delves into skin aging, nutrition, and lifestyle choices in a captivating podcast conversation. Topics include collagen supplements for skin health, hormonal changes post-menopause, sunscreen selection, non-invasive fat reduction, breast implant illness, and the impact of Botox. Stay tuned for valuable insights on healthy aging and skincare support!

Today, I am thrilled to be connecting with Jillian Turecki, a renowned relationship coach, educator, author, and host of the Jillian on Love podcast. Sought out for her empathetic approach, Jillian has guided 1000s of individuals over the past two decades, driven by an unquenchable curiosity about what makes a relationship thrive. Through her compassion, directness, and authenticity, she has helped them transform their relationships with themselves by focusing on self-growth. In our conversation, we explore the societal expectations for women and how improving our relationships with ourselves allows us to become more authentic in our other relationships. We address loneliness and trauma, unlearning parental conditioning, and dealing with situationships, and get into the difference between sexual chemistry and a real connection, narcissism, and warning signs in relationships. Jillian also shares her perspective on marriage and the importance of self-reflection. Join us for the invaluable insights Jillian has drawn from her extensive experience over the past twenty years. IN THIS EPISODE YOU WILL LEARN: How women internalize narratives of weakness due to societal expectations How self-esteem impacts relationship choices What people can do to empower themselves and avoid feeling alone The benefits of self-validation What we can do to heal past wounds and foster healthy relationships The challenge of distinguishing lust from love Why self-awareness is essential within relationships Red flags to look out for in relationships How to deal with communication breakdowns in relationships Tips for moving on from a broken heart BIO:Jillian Turecki is a certified relationship coach, teacher, author, and host of the Podcast, Jillian On Love. Fueled by an insatiable curiosity about what makes a relationship thrive, Jillian has helped thousands over the last 20 years through her teachings, courses, and writing to revolutionize their relationship with themselves so that they transform their romantic relationships. Jillian is sought out for her compassionate, direct, and very authentic style of coaching, teaching, and writing.Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Jillian Turecki On her website On Instagram or Jillian On Love on Instagram Jillian On Love Podcast

I am honored to connect with Dr. Dave Diamond today.Dr. Diamond is a professor at the University of South Florida in their Department of Psychology, Molecular Pharmacology, and Physiology. He has a Ph.D. in biology, specializing in behavioral neuroscience.In our discussion today, Dr. Diamond talks about his journey as a neuroscientist and his interest in heart disease, and we discuss how Ancel Keys, the nutritional department at Harvard, and governmental dietary guidelines have significantly hindered our state of health. We explore the diet-heart hypothesis, the effects of seed oils and low-fat diets, the misconceptions surrounding cholesterol, metabolic errors, and the role of insulin resistance in coronary artery disease and metabolic health. We also scrutinize the implications of scientific misconduct, the effects of statins, and the role of nutrition in shaping lipid panels. Join us for today’s valuable, insightful, and informative conversation with Dr. Dave Diamond. IN THIS EPISODE YOU WILL LEARN: How Dr. Diamond became a leading voice in heart disease research The negative impact of a low-fat, high-carb diet  How the American Heart Association ignored the effects of sugar on heart disease How seed oils have contributed to the obesity epidemic  Why a low-carb diet could increase the risk of heart disease How the demonization of cholesterol deflects from nutritional factors exacerbating poor metabolic health How the benefits of statins get overstated  How statins can lead to strokes and heart attacks and contribute to metabolic damage The perils of scientific misconduct and the profit-driven pharmaceutical industry The benefits of a low-carb diet Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. David Diamond On X (Twitter)   Email Dr. Diamond: ddiamond@usf.edu

I am happy to connect with Coach Bronson Dant today. He has spent over a decade guiding and training people in health and fitness. He discovered the benefits of a whole food animal-based ketogenic diet for optimizing metabolic health and performance and wrote The Ultimate Ketogenic Fitness Book.In our discussion today, we dive into the powerful story of Coach Bronson’s pain-to-purpose journey. We explore the value of mindset and look at how age-related changes affect muscle, inflammation, and metabolic flexibility. He shares his three pillars of muscle health related to nutrient density, bioavailability, and satiety, and we examine the importance of sleep, the impact of extremes in exercise, and the value of stress management. We also unravel the complexities of weight loss resistance, and Coach Bronson discusses his research from the Journal of Nutrition Metabolism and Health Science, sharing his perspective on macros and functional movement in menopausal women.IN THIS EPISODE YOU WILL LEARN: Coach Bronson shares his three pillars for nutrition The limitations of basing nutrition on calories alone How the hormone piece impacts effective weight management How to avoid physical deterioration through fitness and nutrition Why Coach Bronson advocates for living life to the fullest and dying quickly How does muscle mass impact metabolic health? The importance of taking a balanced approach to weight loss How sleep aids muscle recovery and growth  Stress management, nutrition, and fitness for overall well-being How alcohol affects our health and fitness The benefits of combining functional movement training and proper nutrition for older adults  Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Bronson Dant On his website  On YouTube and Instagram The Ultimate Ketogenic Fitness Bundle is available on Amazon