“We have, because of the nature of our information landscape now, essentially zero capacity to hold any accountability to sources of misinformation. So it's a really terrible time to be an evidence-based healthcare professional.” -Dr Alan Flanagan Dr Alan Flanagan is a major myth buster in the nutrition space, holding an MSc and PhD in nutrition from the University of Surrey. In this episode Alan and I debunk common nutrition advice you might be following, and explain the dangerous real life impact online influencers and “gurus” are having on your health. Stay tuned to find out: The dangers of following extreme diets like keto and carnivore Why you don’t need to be worried about glucose spikes The limitations of personalised nutrition and microbiome research Why sweeteners and seed oils have been wrongly demonised How to spot a charlatan online Chapters (2:12) Real life consequences of misinformation (8:00) Why people look to online “gurus” (13:17) Personalised nutrition con (20:36) Continuous glucose monitors (26:59) Seed oils are healthy! (32:50) Artificial sweeteners (39:49) Cancer misinformation (45:18) Does the time you eat matter? (49:22) Microbiome research (54:21) How to spot a charlatan online Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.

“The human body is made for pleasure. Every bit of your body can give you an intense amount of pleasure. It just depends on how you treat it” -Seema Anand Seema Anand is an expert in sexual health and pleasure and an authority on the ancient Indian text the Kama Sutra. In this episode Seema and I break the taboo around sex and she explains how people can find a deeper sense of pleasure and sexual satisfaction in their relationships. Stay tuned to find out: The real meaning of the Kama Sutra and what it teaches us about sexual pleasure How to start exploring your own pleasure senses Why you should listen to erotic podcasts instead of watching porn How to actually satisfy your partner in bed Chapters (2:03) Religion and sex (4:51) Truths about the Kama Sutra (12:09) The orgasm gap (16:19) Increase your pleasure diet (26:00) How men can pleasure their partners (33:55) How to increase libido (36:28) Tackling shame in relationships (38:36) Bedroom red flags (42:10) “No fap” and other myths (46:02) Why we’re having less sex Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.

“The vegans hate the carnivores. The carnivores hate the keto people. And a lot of these folks are in a battle for a non-existent entity, and that entity is the crowned king of ‘this is the best diet for everyone’.” -Dr Mike Israetel Dr Mike Israetel is an exercise scientist, bodybuilder, YouTuber and founder of Renaissance Periodization. He’s known for his no-nonsense, science backed approach to fitness and diet. In this episode, I ask Mike just how often and how hard you have to workout for health, and whether there really is one diet that is best for everyone. Stay tuned to find out: What diet tribes get wrong about good nutrition Why you can get away with training a lot less than you think The truth behind “calories in, calories out” Whether nutrient timing is important Why creatine might just be the best supplement around Chapters (2:00) How little can you workout? (10:19) Calories in, calories out (18:57) Which diet tribe is right about health? (26:25) Are artificial sweeteners bad for you? (34:46) Why diet is so individualised (40:35) The benefits of creatine (47:47) Nutrient timing and protein absorption (55:26) Dr Mike’s 4 tenants for success Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.

“If you enjoy coffee, just go and enjoy coffee, and the data in general suggests that actually caffeine or coffee consumption overall is very beneficial for a number of health outcomes.” -Dr Bryan Saunders Dr Bryan Saunders is a researcher at the University of São Paulo, who specialises in the study of caffeine, and in particular its effects on exercise performance. He’s co-authored multiple studies on the topic and sheds light on many of the myths that are perpetuated online. In this episode, I ask Bryan how caffeine is affecting our bodies, everything from the mechanisms behind its ergogenic effects to the truth behind habitual coffee consumption. Stay tuned to find out: Whether your morning coffee really is bad for your health How caffeine improves exercise performance Whether caffeine actually stops affecting you the more you consume it If genetic variations mean some people are immune to its effects When you need to stop drinking caffeine for a good night’s sleep Chapters (1:56) Morning coffee effects and your adenosine system (8:27) Does caffeine affect habitual coffee drinkers? (10:58) Placebo effect of morning cuppa (14:29) Non-caffeine benefits of coffee (15:40) Boosting exercise performance (21:57) The dose you need (24:10) Ideal time to consume caffeine (25:38) Negative effects of overconsumption (30:13) Feeling more TIRED after caffeine? (34:23) Do you need a caffeine fast? (37:45) Half-life of caffeine and sleep impacts (43:34) Long-term physiological effects of caffeine (45:33) Differences between coffee beans Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.

“A lot of women's health stuff - there's no easy diagnosis. So very, very often women's health things end up getting put into, you have fibromyalgia, you're a hypochondriac, or something like irritable bowel syndrome.” -Dr Karen Tang Dr Karen Tang is a gynaecologist who specialises in the treatment of pelvic pain, endometriosis and fibroids. She also does a great service educating the public on social media, raising awareness of women’s health issues. In this episode, I ask Karen how people can figure out what’s causing their pelvic pain, what surprising habits may be causing problems, how patients can better advocate for themselves, and how she’d reimagine sex ed. Stay tuned to find out: Why “stabbing butthole pain” has gone viral, and what it actually is Why endometriosis is so commonly misdiagnosed as IBS How female anatomy, especially the uterus, does NOT look like it does in the textbooks Why we should teach children the proper names for their reproductive organs Why you should get a pelvic floor PT! Chapters (1:24) Stabbing butthole pain (4:36) Endometriosis - more than a pelvic condition (6:43) Endo vs IBS (8:45) How much pain is too much? (10:38) The link between gynaecological conditions (13:20) Being proactive about your health (16:14) How to advocate for yourself at the doctor’s (21:56) Actionable tips for perimenopause/menopause (26:04) How to take care of your pelvic floor health (31:36) What the uterus actually looks like (34:49) Reimagining sex sed (36:53) Teaching children about sexual health (38:26) The plague of misinformation Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBookAn OG Podcasts production.

“Like most other herbal medicines, CBD is understudied, unregulated, and often wrongly vilified.” -Dr Jeff Chen Dr Jeff Chen is co-founder of Radicle Science and is doing tons of research advancing our understanding of CBD and other herbal remedies. In this episode, I ask Jeff about the new science of CBD - both its potential health benefits and challenges. We also explore the promising trials into another cannabis compound - CBN. Stay tuned to find out: How effective CBD is for sleep, anxiety, pain and more How stigma and regulatory hurdles have hampered scientific progress What you should be looking for when buying CBD products How Radicle’s crowd-sources clinical trials are shedding light on many herbal remedies Chapters (1:54) What is CBD? (3:27) Why herbal remedies are dismissed (8:59) Crowd-sorucing data on CBD and CBN (14:13) Avoiding bias and determining placebo (19:46) Science of the endocannabinoid system (25:11) Safety of OTC CBD supplements (29:30) Optimal delivery route of CBD (33:21) Best cases for CBD in clinical settings (36:46) Choosing the right product - an unregulated market (48:07) Benefits of lion’s mane mushrooms Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.

“Ozempic has changed the conversation around obesity. Unfortunately a lot of people are misusing the medication.” -Dr Andres Acosta Dr Andres Acosta is an obesity expert at the Mayo Clinic, and regularly helps patients achieve double digit weight loss thanks to semaglutide, often branded as Ozempic or Wegovy. But as healthy people look to it for a quick fix, he raises a red flag about the drug. In this episode I ask Andres how Ozempic works, what are its side-effects, and who should actually be taking it. Plus what else works for treating obesity. Stay tuned to find out: The risks and rewards of Ozempic What’s going on in the brains of people who struggle with their weight How his lab has identified 4 genetic phenotypes causing obesity Where Dr Acosta stands on “body positivity” How his work is destigmatising obesity How close we are to a cure Chapters (1:55) Misusing Ozempic (4:35) Ozempic for longevity and health (7:49) Diet and exercise vs Ozempic + risks (10:55) Do you need to take Ozempic forever? (14:24) Link between the gut and obesity (19:16) Why obesity is rising (25:43) Weight loss vs fat loss vs health (25:36) Cutting edge therapies for obesity (40:19) A cure for obesity? (43:12) The problem with BMI (47:21) Why “fat” doesn’t equal “lazy” (49:51) The body positivity movement Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr Learn more about Dr. Acosta's work: https://phenomixsciences.com/ For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.

Dr Jen Gunter, an OB/GYN busting myths about women’s health, discusses period taboos, cycle syncing, PMS, endometriosis, birth control myths, forever chemicals in tampons, and the vaginal microbiome. She reveals the lack of medical research in female reproductive health, advice for painful periods, and the demonization of birth control. Jen also addresses the benefits of exercise, challenges period myths, and the importance of evidence-based research in women's health products.

“The last 55 years of banning psychedelics is the worst censorship of research in the history of the world.” -Professor David Nutt Professor David Nutt is THE go-to expert on psychedelics. His charity Drug Science is on a mission to break the stigma around hallucinogenic drugs, and inform the public on the real science behind their effects. In this episode I ask David how drugs like magic mushrooms, MDMA, cannabis and Ketamine are able to treat brain disorders, like depression, so effectively - and why we’ve been led to fear these drugs. Stay tuned to find out: The truth about why psychedelics were banned in the first place How safe these drugs are in both a medical and recreational setting Whether human evolution was driven, in-part, by psilocybin mushrooms About the most recent science and trials Myths and misinformation surrounding their use How soon we might see the legalisation of psychedelics Highlights (1:41) 50 years of censorship (7:12) Emerging research (10:24) Safety of psychedelics (12:47) The stoned ape theory (19:12) How psychedelics treat depression (22:48) When will they be legal? (25:38) Physiological changes in the brain during use (29:54) Psychedelics versus conventional methods (32:47) Recreational use (35:47) Microdosing (39:06) Enduring benefits of psychedelics (42:26) Misinformation (44:05) Treating addiction (47:13) Future legalisation Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.

“It’s not that we’ve lost some microbes, it’s actually that we’ve gained others. And the ones that we’ve gained are causing us harm.” Professor James Kinross is a world-leading microbiome expert and bowel cancer surgeon at Imperial College London. He’s also the author of Dark Matter: The New Science of the Microbiome. In this episode I ask James about the impact of gut health on all aspects of our bodies, from growth to immune function to brain health and even personality. He also shares advice on the food you should be eating to get your gut health in check - science backed and BS-free. Stay tuned to find out: How the microbiome is modifiable - you’re not doomed to have poor gut health How to figure out whether you have a healthy gut, and what that actually looks like Whether probiotics are more hype than health The important role of fibre in gut health - and how to get more of it Why cooking your own food is so important How ultra-processed food changes the microbiome The environmental factors you can alter to improve gut health Highlights (1:35) What is the microbiome? (4:05) What impacts the development of the microbiome? (9:44) Combating “bad” gut health (15:17) Are probiotics any good? (22:39) De-Westernising your diet (26:46) Problem of ultra-processed food (32:48) Impact of the modern environment on gut health (42:43) Fibre’s role in gut health (49:39) Are artificial sweeteners ok? (51:56) Intermittent fasting Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook An OG Podcasts production.