Duke Rohlen, Founder and CEO of Ajax Health, and Regina Herzlinger, a Harvard Business School professor, dive into healthcare innovation. They discuss Rohlen's 'Chassis and Growth Drivers' model designed to align incentives for innovation and financial success. The duo debates the $1 billion bid for Cordis and its potential impact. They explore the high stakes of funding models, the challenges of adapting technology, and the critical role of leadership in overcoming hurdles within the medical tech industry.

James K. Sebenius, a Harvard Business School professor and founder of the school's negotiations unit, dives into the fascinating world of high-stakes deals. He discusses John Branca's strategic negotiation for the Beatles' Northern Songs catalog, emphasizing the blend of cooperation and tough bargaining. Sebenius highlights ethical dilemmas and the emotional components at play, revealing how these dynamics influence outcomes. The conversation also touches on unexpected moments, like an intriguing call from Richard Branson, that shape negotiations in the music industry.

Yavor Bozhanov and Edward McFowland III, both Harvard Business School professors, delve into Pernod Ricard's digital transformation journey. They discuss how the company embraces AI to enhance data-driven decisions while overcoming internal resistance. The need for a strong data culture is emphasized, along with leadership's role in integrating AI. Additionally, they highlight the challenges of maintaining data integrity across global operations and the vital importance of a collaborative environment to successfully implement these technological advancements.

Rick Ruback, a Harvard Business School professor specializing in corporate finance, and Joe Higgins, an executive fellow and former president of Visual Comfort & Company, explore the powerful impact of Lucky Ones Coffee in Park City, Utah. They discuss how this coffee shop uniquely employs individuals with disabilities, emphasizing the for-profit model's effectiveness in addressing unemployment. The duo highlights the community's role in supporting inclusivity, innovative hiring strategies, and the transformative benefits of meaningful employment on both employees and workplace culture.

Jo Tango, a Senior lecturer at Harvard Business School with a rich background in venture capital, and Christina Wallace, an author and expert on tech ventures, dive into the evolution of Sequoia Capital. They discuss the balance of nurturing unicorns while navigating recent shifts in leadership and investment strategies. The conversation covers the impact of COVID on industry dynamics and the importance of sustainable growth strategies amidst a changing economic landscape, highlighting lessons for future leaders.

Brooke Boyarsky Pratt, the founder and CEO of KnownWell, and Jon Jachimowicz, an assistant professor at Harvard Business School, engage in a heartfelt discussion about addressing obesity care. They explore Brooke’s personal battle with weight stigma and her mission to create an inclusive healthcare option. The duo weighs the challenges of scaling her venture against personal passion and the intricacies of navigating career transitions. They also touch on the stigma surrounding obesity in healthcare and the emotional toll of starting a new chapter in one's career.

Fawn Weaver, an entrepreneur and founder of Uncle Nearest, shares her inspiring journey in the spirits industry, facing hurdles as a Black woman in a male-dominated market. She discusses innovative strategies and the power of storytelling in building her award-winning whiskey brand. With plans to expand into the cognac sector, she reveals her vision for disrupting a traditional industry. Throughout the conversation, leadership, community ties, and the importance of human connection are emphasized as keys to her entrepreneurial success.

Gina Raimondo, the U.S. Commerce Secretary, discusses her pivotal role in authorizing $39 billion for semiconductor manufacturing, emphasizing innovative funding strategies. She highlights the significance of the CHIPS Act in revitalizing the U.S. semiconductor industry post-COVID. The conversation dives into the challenges of risk management in government funding and the necessity of a transparent application process. Raimondo also shares insights on balancing technological leadership with responsible taxpayer funding.

Kara Nortman, a venture capitalist, Julie Uhrman, an entrepreneur, and Natalie Portman, an actor and activist, co-founded Angel City Football Club to revolutionize women's sports. They discuss their innovative business model that prioritizes gender equity and community engagement. The trio shares insights on balancing brand-building with player development and the club's rapid rise, achieving a market valuation of $250 million. Their commitment to pay equity and inclusivity in sports challenges traditional norms and inspires a new era of women's athletics.

Jeff Maggioncalda, the CEO of Coursera, shares insights on integrating generative AI into education. He reveals how four key projects are reshaping content delivery, enhancing personalized coaching, and automating course creation. The conversation dives into the competitive landscape, urging companies to continually innovate to stay ahead. Maggioncalda also discusses the balance between rapid tech adoption and ethical concerns, emphasizing the importance of providing accessible education in a fast-evolving digital world.