

Osterholm Update
CIDRAP
A weekly report on the COVID-19 pandemic from infectious disease expert Michael Osterholm, PhD, MPH. Dr. Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota and has spent a career investigating outbreaks. Since 2005, he has emphasized supply chain and other vulnerabilities and a critical need for pandemic preparedness. In this podcast, Dr. Osterholm dissects the latest COVID-19 news, data, and guidance.
CIDRAP’s Chris Dall, MA, is the cohost of the Osterholm Update and a reporter for CIDRAP News. http://www.cidrap.umn.edu
CIDRAP’s Chris Dall, MA, is the cohost of the Osterholm Update and a reporter for CIDRAP News. http://www.cidrap.umn.edu
Episodes
Mentioned books

Dec 8, 2025 • 0sec
Special Episode: ACIP's Hepatitis B Vaccine Decisions
A recent decision by the ACIP to end universal hepatitis B birth dose recommendations raises alarms about public health. Dr. Osterholm expresses concerns over the implications for trust in federal vaccine guidance. He reviews the effectiveness of historical strategies against hepatitis B and highlights critical gaps in prenatal screening. Without new safety data, he predicts a rise in infant infections. The discussion also touches on the ideological motivations behind the decision, suggesting future threats to other vaccine recommendations.

Dec 4, 2025 • 0sec
Episode 197: Fork in the Road
The discussion reveals shocking changes to the CDC's stance on vaccines and autism, eroding public trust. Dr. Osterholm highlights an alarming infant botulism outbreak linked to formula and criticizes potential bureaucratic changes affecting vaccine recommendations. He expresses concerns over the recent appointment of an anti-vaccine advocate to the CDC. Additionally, perspectives on the implications of stricter standards for vaccine approvals raise ethical questions. The latest updates on respiratory viruses and C. difficile vaccine candidates provide crucial insights.

Nov 20, 2025 • 0sec
Episode 196: Flu Shifts: Why Vaccines Still Matter
Explore the latest trends in flu, including a potential vaccine mismatch with emerging H3N2 subclade. Discover the unfortunate loss of measles elimination status in Canada and the implications for the U.S. Learn about the H5N1 outbreak affecting mammals in Antarctica and why its severity varies by species. Delve into the serious issue of infant botulism linked to formula recalls. The discussion emphasizes the critical importance of vaccination and public health efforts against respiratory illnesses.

Oct 30, 2025 • 0sec
Episode 195: We Can Make a Difference
Dr. Osterholm and Chris Dall dive into the latest on measles outbreaks in the U.S., highlighting low vaccination rates and the urgency of public health efforts. They discuss the Vaccine Integrity Project's recent findings on COVID-19, RSV, and influenza vaccines, along with upcoming public health alerts. Concerns around avian flu surveillance and the impact of a government shutdown on public health data are raised. The episode emphasizes the importance of effective vaccine messaging and community engagement in health advocacy.

5 snips
Oct 16, 2025 • 0sec
Episode 194: Bending Not Breaking
The discussion delves into recent layoffs and reinstatements at the CDC, highlighting the implications for public health. Experts examine vaccine guidance for COVID, especially concerning pregnancy. Rising pertussis cases spark conversations on vaccine schedules and booster importance. The hosts analyze low flu and RSV activity, recommending timely vaccinations. Insights into H5N1 outbreaks in poultry are shared, alongside a comprehensive look at herd immunity and its significance in communities.

Oct 2, 2025 • 0sec
Episode 193: Fevers, Furloughs, and Falsehoods
<p>In "Fevers, Furloughs, and Falsehoods," Dr. Osterholm and Chris Dall break down the CDC’s recent ACIP meeting and the ongoing uncertainty around updated vaccine recommendations. Dr. Osterhom discusses state-level differences in vaccine access, possible changes to the National Vaccine Injury Compensation Program, and reviews the latest data on COVID-19, Ebola, and STIs. Dr. Osterholm also answers an ID Query on the studies associating acetaminophen (e.g., Tylenol) use during pregnancy and autism, and share the latest installment of This Week in Public Health History on the 2001 anthrax attacks.</p>
<p><a href="https://www.kff.org/covid-19/tracking-state-actions-on-vaccine-policy-and-access/">Tracking State Actions on Vaccine Policy and Access (KFF)</a></p>
<p><a href="https://www.cidrap.umn.edu/vaccine-integrity-project/viewpoint-four-tips-understanding-week-s-acip-meeting">Vaccine Integrity Project Viewpoint: Four tips for understanding this week’s ACIP meeting</a></p>
<p><a href="https://www.cidrap.umn.edu/vaccine-integrity-project/immunization-info">Vaccine Integrity Project - Fall Immunization Information</a></p>
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<p><strong>Resources for vaccine and public health advocacy:</strong></p>
<p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p>
<p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p>
<p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p>
<p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p>
<p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p>
<p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p>
<p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a> </p>
<p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>

Sep 22, 2025 • 0sec
Special Update: Dysfunction at ACIP
In a recent update, hosts dive into the chaos at the ACIP meeting, highlighting disarray in COVID-19 vaccine guidelines. They discuss the contentious debates surrounding childhood vaccinations, particularly the MMRV febrile seizure risks. The confusion over hepatitis B newborn vaccinations adds to the drama of the meeting. Tune in for insightful commentary on these critical vaccine discussions and what they mean for public health.

11 snips
Sep 18, 2025 • 0sec
Episode 192: Ice Cream and Shark Attacks
Dr. Osterholm and Chris Dall dive into the FDA's recent authorization of updated COVID vaccines for select groups, alongside confusion regarding vaccine access for those under 65. They discuss turmoil at the CDC, providing current COVID statistics and addressing the resurgence of measles in the U.S. The conversation also highlights the significance of Chagas disease, explaining its transmission and prevention. Listeners can look forward to historical public health insights and advocacy tips, all while navigating these pressing health issues.

Sep 3, 2025 • 0sec
Episode 191: 'The Big One' with Mark Olshaker, Ann Hennigan Grace, & Dr. Sydney Redepenning
<p>In this week's special episode, Chris Dall interviews Dr. Osterholm and his coauthor Mark Olshaker on their new book <em>The Big One: How We Must Prepare for Future Deadly Pandemics</em>. They are also joined by Ann Hennigan Grace and CIDRAP's Dr. Sydney Redepenning who both conducted research and fact-checking for the book.</p>
<p>The Big One is available for purchase <a href="https://www.hachettebookgroup.com/titles/michael-t-osterholm-phd-mph/the-big-one/9780316258340/?lens=little-brown-spark">online</a> and at your local bookseller!</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a> </p>
<p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>

Aug 21, 2025 • 0sec
Episode 190: Courage Over Fear
A tragic shooting at the CDC headquarters underscores the rising threats to public health officials. Discussion shifts to the courage these individuals show despite increasing hostility. The episode delves into the importance of mRNA vaccines and the implications of funding cuts for pandemic preparedness. Emerging threats from H5N1 avian flu and its alarming presence on dairy farms are highlighted. Misconceptions about vaccine adjuvants are addressed, emphasizing informed understanding in the vaccination debate. Resilience and empowerment in public health amid challenges complete the conversation.


