Osterholm Update Episode 199: Flu Takes Charge
Jan 2, 2026
Dr. Osterholm dives into the pressing issues of the emerging flu season and its regional impacts. The discussion highlights concerns over vaccine effectiveness, especially regarding the MMR vaccine's declining public confidence. Urgency for vaccination is emphasized alongside the effectiveness of antiviral treatments. There’s a notable update on COVID activity and RSV trends, as well as a close look at the Vaccine Integrity Project’s recent video. The podcast wraps up with a reflection on public health history and the importance of community resilience.
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40 Years Reading The Polar Express
- Michael Osterholm read The Polar Express to his kids and grandkids for the 40th consecutive year.
- He presents the episode as dedicated to those who carry hope into the new year for public health.
Act Fast On Flu Vaccination And Care
- Get your flu shot now, especially if you're high risk, because the season is already widespread.
- Stay home if you have influenza symptoms and seek antivirals promptly if you are vulnerable.
New H3N2 Subclade Driving Surge
- A large portion of the current H3N2 surge is due to a newly emerged subclade K that differs from the vaccine strain.
- Early international data still showed moderate vaccine protection against severe outcomes despite the mismatch.