
Osterholm Update Episode 197: Fork in the Road
Dec 4, 2025
The discussion reveals shocking changes to the CDC's stance on vaccines and autism, eroding public trust. Dr. Osterholm highlights an alarming infant botulism outbreak linked to formula and criticizes potential bureaucratic changes affecting vaccine recommendations. He expresses concerns over the recent appointment of an anti-vaccine advocate to the CDC. Additionally, perspectives on the implications of stricter standards for vaccine approvals raise ethical questions. The latest updates on respiratory viruses and C. difficile vaccine candidates provide crucial insights.
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CDC Website Shift Undermines Trust
- The CDC changed its autism-vaccine page to suggest vaccines might not be ruled out as a cause of autism, undermining trust.
- Michael Osterholm warns this shift signals politicization and erosion of CDC credibility.
Burden Of Proof Belongs To Claimants
- Osterholm argues the burden of proof should rest on those making vaccine claims, not on scientists to disprove every possibility.
- He notes rigorous studies found no evidence linking vaccines to autism, even when signals prompted investigation.
New CDC Deputy's Troubling Record
- Osterholm outlines Ralph Abraham's record spreading vaccine misinformation and ending mass vaccination campaigns in Louisiana.
- He warns Abraham's quiet appointment as CDC deputy director threatens vaccine access and public health.


