80k After Hours

Dwarkesh Patel, a young podcast host, shares insights on landing top guests and discusses ideological labels. Topics range from the impact of Microsoft vs. Gates Foundation, motivating people in government, boosting agency, and navigating career decisions. The conversation dives into balancing technical skills with big ideas, exploring power, ambition, and altruism, and embracing unconventional paths in entrepreneurship. It culminates in reflections on growth, adaptation, brand perception, and handling controversies.

Rob Wright and Rob Wiblin discuss topics like Sam Bankman-Fried, virtue ethics, longtermism, EA's role in OpenAI drama, fears about rogue AI, and societal impacts of AI advancements in an engaging discussion.

Spencer Greenberg discusses causation without correlation, money and happiness, hype vs value, and more. Topics include balancing hype and value for success, recognizing acclimated problems, exploring values in decision-making, and supporting individuals with false perceptions or delusions.

Bob Fischer, a specialist in comparing animal welfare, discusses topics like alternative assessments for animal welfare beyond neuron counts, intense pain experiences in smaller-brained creatures, moral considerations in resource allocation between humans and bees, the concept of multiple minds in species like birds and octopuses, the impact of beliefs on welfare assessments, evaluating welfare beyond happiness with enduring physical pain, and exploring moral implications of suffering in humans and animals.

Discussing the new nuclear age dynamics involving the US, Russia, and China, the role of AI in military systems, and philanthropists focusing on post-catastrophe interventions. Emphasizing the importance of policy considerations to reduce devastating effects of global catastrophic risks.

In this podcast, Laura Deming discusses challenging conventional beliefs on aging and healthspan, exploring implications of longer lives and agency over lifespan. The conversation delves into advancing medical research, strategies to extend lifespan in mice, and the potential impact on human health. A fascinating look at the science that could keep us healthy in our 80s and beyond.

Topics in the podcast include moving to America, British vs American politics, struggles with mental health, cultural differences, living in filth vs simplicity, applying for CEO position, spectrum of phantasia, and effective altruism reflections

Exploring evolution of skepticism and communication dynamics, AI's impact on information quality, psychology of belief and vaccination hesitancy, open vigilance, and belief dynamics. Delving into why gullibility and misinformation are overrated.

Explore the evolutionary origins of emotions like anxiety and sadness. Understand how evolution has left humans vulnerable to depression. Delve into the relationship between low mood, unreachable goals, and mental health. Discover the misconceptions and realities of anxiety and depression rates. Learn about the evolution of emotions and morality in human behavior.

Join the podcast team and guest Chana Messinger as they discuss effective altruism, family perspectives on intellectual pursuits, navigating perceptions of importance, truth-seeking in adversarial systems, interactions and pub trivia banter, insights on weddings and personal growth, nuances of apologies and reflections on drinking behavior, redefining work and career satisfaction, striking a balance in human interactions, and unraveling the origins of the term 'steelman'