
CXOTalk
In-depth conversations on AI and business with senior leaders from top global companies and innovative startups. Hosted by industry analyst Michael Krigsman.
Latest episodes

14 snips
Jun 25, 2025 • 53min
Prompt Engineering Advice | CXOtalk 883
AI expert Nate B. Jones, popular on TikTok for his innovative insights, dives into the art of AI prompting. He discusses how effective prompting can enhance the performance of large language models and improve AI productivity. The conversation touches on the balance leaders must find between AI insights and their expertise. Jones also emphasizes the craft of creating specific prompts for better AI responses and explores the impact of AI on data analysis. His tips are invaluable for anyone looking to leverage AI effectively.

Jun 9, 2025 • 56min
AI Inequality EXPOSED: When Algorithms Fail | CXOTalk #882
In this engaging conversation, Kevin De Liban, founder of TechTonic Justice and former legal aid attorney, unveils the disturbing effects of AI on 92 million low-income Americans. He shares his pivotal legal victory challenging an algorithm that harmed disabled Medicaid recipients. De Liban explains why these technologies often reflect biases rather than neutrality, and how self-regulation typically falls short. He stresses the urgent need for robust regulation to protect vulnerable communities and offers actionable advice for technology leaders to ensure ethical practices in AI.

7 snips
May 26, 2025 • 53min
Are You Making These COMMON AI Organization Mistakes? | CXOTalk #881
Jeetu Patel, President and Chief Product Officer at Cisco, shares insights on transforming businesses into AI-native organizations. He discusses the cultural shift needed to embrace AI, emphasizing training and curiosity-driven growth. Patel warns that AI won't replace jobs, but users who excel with AI will thrive. He highlights ethical AI implementation, the importance of integrating diverse perspectives, and the future of agentic AI. The conversation offers actionable strategies for leaders navigating the AI landscape and stresses the need for proactive regulation.

May 21, 2025 • 54min
What Big Changes Are Coming to AI in 2025? | CXOTalk #880
Nate B. Jones, an AI strategist and TikTok commentator, joins to dissect the evolving AI landscape amidst a fierce arms race among tech giants like OpenAI and Google. He delves into token economics and the nuances of model specialization, emphasizing the skills executives must develop for effective AI usage. The discussion highlights how AI could revolutionize workplace tools and the psychological dynamics between humans and AI. Jones also addresses the importance of adaptability in navigating AI's economic challenges and the critical role of tailored AI interactions for business success.

May 8, 2025 • 23min
Will AI Change Customer Service Forever in 2025? | CXOTalk #879
Join GoTo and CXOTalk for a deep dive into the world of AI and the virtual workforce. Learn about AI receptionists, agentic AI, and how AI agents dramatically improve customer service for small and mid-sized companies.Our guest is Damon Covey, General Manager of UCC at GoTo.Learn more at: www.goto.com🔔 Don’t forget to like, subscribe, and share for more thought-provoking conversations with top industry leaders.🔷 Newsletter: www.cxotalk.com/subscribe🔷 Read the summary and key points: https://www.cxotalk.com/episode/ai-receptionists-transforming-customer-service🔷 LinkedIn: www.linkedin.com/company/cxotalk🔷 Twitter: twitter.com/cxotalk00:00 AI's Role in Customer Communication01:19 Examples and Benefits of AI in Small Business05:49 AI Receptionist and the Future of Virtual Workforce08:33 Benefits of AI Receptionists and Virtual Workforce11:27 Deployment and Integration of AI Systems17:11 Collaboration Between AI and Human Workforce20:00 Ensuring Privacy and Security in AI Systems21:16 The Future of AI: Personalization and Actionability22:28 Closing Thoughts and Mission Statement

May 6, 2025 • 23min
AI Agents for Small Business: What You Need to Know | CXOTalk #878
Join Andrew Wesbecher (Powered_By) and Michael Krigsman on CXOTalk episode 878 to discuss how AI agents can help small businesses succeed in 2025. Learn from industry experts and discover the benefits of using AI technology for your SMB to stay ahead of the competition!Learn more from www.poweredby.agency===================🔔 Don’t forget to like, subscribe, and share for more thought-provoking conversations with top industry leaders.🔷 Newsletter: www.cxotalk.com/subscribe🔷 Read the summary and key points: https://www.cxotalk.com/episode/ai-agents-for-small-business-winning-in-2025🔷 LinkedIn: www.linkedin.com/company/cxotalk🔷 Twitter: twitter.com/cxotalk00:00 Democratizing AI for Small to Medium-Sized Businesses02:38 Technical Architecture and AI Agent Implementation07:59 Use Cases and Ethical Considerations11:14 The Evolution and Capabilities of AI Agents13:27 Practical Use Cases and Optimization of AI Agents18:43 ROI and Democratization of AI Agents for SMBs#aiagents #smb #smallbusiness #cxotalk

May 1, 2025 • 54min
What If AI Could SPEED UP Clinical Trials by 90%? | CXOTalk #877
Learn about the impact of AI in healthcare in CXOTalk episode 877 on AI in clinical trials. Discover how artificial intelligence is revolutionizing clinical trials and the potential benefits for the healthcare industry.AI promises faster, safer clinical trials and better patient experiences. Clario's EVP & Chief Information Technology & Product Officer, Jay Ferro, joins CXOTalk host Michael Krigsman to explain how his team unifies IT, product, data, security, and marketing under one roof, giving sponsors, sites, and patients a single, seamless platform. He outlines responsible AI governance with legal, medical, privacy, and security leaders. He shows how predictive tools speed recruitment, sharpen protocol design, cut dropout risk, and support image interpretation while physicians keep the final judgment.Watch to learn• How a unified tech-product structure cuts cost and removes friction• Steps for enterprise-wide AI oversight in a regulated environment• Real use cases for AI in recruitment, imaging, and trial optimization🔔 Don’t forget to like, subscribe, and share for more thought-provoking conversations with top industry leaders.🔷 Newsletter: www.cxotalk.com/subscribe🔷 Read the summary and key points: https://www.cxotalk.com/episode/ai-in-clinical-trials-what-you-need-to-know🔷 LinkedIn: www.linkedin.com/company/cxotalk🔷 Twitter: twitter.com/cxotalk00:00 🧬 The Role of AI in Clinical Trials01:18 🔗 Unified Roles and Seamless Experiences10:45 📉 Customer Concerns and Future Challenges11:54 🔬 Navigating Uncertainty in Clinical Research13:13 ⚖️ Balancing Priorities and Saying 'No' Strategically18:02 🤖 AI's Role in Healthcare and Clinical Trials24:07 🤖 Ensuring Responsible AI Development27:19 🧪 AI's Role in Clinical Trials32:23 📜 Navigating Regulatory Challenges and Organizational Readiness36:24 🤝 Proactive Collaboration and Regulatory Compliance in AI Development38:57 🌐 Transparency and Cross-Industry Collaboration in AI42:12 🔗 Industry Similarities and the Role of Technology44:40 💡 Purpose-Driven Technology and AI in Healthcare50:15 🚀 Scaling AI Projects and Overcoming Adoption Challenges#AI #ClinicalTrials #DigitalHealth #CIO #cxotalk

Apr 17, 2025 • 52min
Will AI Agents Replace Your Entire Workforce in 2025? | CXOTalk #876
Phil Fersht, CEO of HFS Research, dives into the evolving landscape of AI in the workplace. He discusses the transformative power of agentic AI, which mimics human behavior and enhances productivity. Topics include the shift from basic AI tools to collaborative agents, the balance of risks like misinformation, and the urgent need for upskilling in an AI-driven market. Fersht highlights the ongoing challenges enterprises face with regulations and the skepticism among executives regarding AI's role in replacing traditional jobs.

Apr 7, 2025 • 57min
AI Regulation & Innovation: Insights from the UK House of Lords | CXOTalk #875
Join Lord Chris Holmes, a technology policy advocate in the UK House of Lords, and Lord Tim Clement-Jones, an expert in AI regulation, as they tackle pressing issues at the intersection of innovation and oversight. They discuss the need for balanced AI regulations that promote innovation while ensuring public trust. Key topics include protecting intellectual property, the importance of international cooperation, and the impact of legal clarity on digital assets. Their insights shed light on the future of technology policy and governance.

Apr 3, 2025 • 54min
AI in Healthcare: Reality, ROI, and Patient Outcomes | CXOTalk #874
Dr. David Bray leads the Accelerator at the Stimson Center, specializing in AI and healthcare. Teresa Carlson is the President of the General Catalyst Institute, focusing on healthcare investments, while Dr. David Reich oversees clinical operations at Mount Sinai Health System. They discuss practical AI applications in healthcare, highlighting integration into workflows and calculating ROI. The conversation touches on data interoperability challenges, the importance of policy collaboration, and the move toward value-based care for improved patient outcomes.