

Mastering Nutrition
Chris Masterjohn, PhD
Welcome to the Mastering Nutrition podcast.
Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks.
He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University of Illinois at Urbana-Champaign's College of Veterinary Medicine from 2012-2014, served as Assistant Professor of Health and Nutrition Sciences at Brooklyn College from 2014-2017, and now works independently in science research and education.
Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks.
He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University of Illinois at Urbana-Champaign's College of Veterinary Medicine from 2012-2014, served as Assistant Professor of Health and Nutrition Sciences at Brooklyn College from 2014-2017, and now works independently in science research and education.
Episodes
Mentioned books

6 snips
Apr 30, 2022 • 16min
Reversing Fatty Liver: How Long Does It Take? | Masterjohn Q&A Files #296
Short answer: You should be able to see changes on imaging within a few weeks if your approach is working well, but ultimately this is entirely dependent on how negative your "delta fatty liver = (fat in) - ((fat out) + (fat burned))" equation is. This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access five other free samples using this link: https://chrismasterjohnphd.substack.com/p/questions-on-vitamin-d-fatty-liver In that batch of free episodes you will also find the answers to these questions: What's the difference between 25(OH)D and 1,25(OH)2D when it comes to the VDR? What if my A1C says I'm diabetic but my CGM says I'm fine? Will reishi, turmeric, or curcumin tank my testosterone? The 3 Phases of Fasting: And How to Get Kicked Out of Each One If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up: https://chrismasterjohnphd.substack.com/qanda Learn more about the Masterpass here: https://chrismasterjohnphd.substack.com/about This snippet is from the April 13, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what's included: How to balance vitamins E and K What prenatal vitamin do I recommend? Why does my smoothie make my hands cold? What type of choline to use? Is there an interaction between glycine and aspirin? What supplements can be used in the fasting state? How to manage protein intake within a small eating window on an intermittent fasting regimen? Looking at a study on calcium alpha-ketoglutarate supplementation. Should I take vitamin D for COVID if I easily get hypercalcemia from it? What to do about nausea in pregnancy? Brief questions on restless legs, exercise during fasting, puffy eyes, and health effects of spicy foods. Here's a link to the full AMA: https://chrismasterjohnphd.substack.com/p/ask-me-anything-april-13-2022 Access the show notes, transcript, and comments here. Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Apr 29, 2022 • 7min
What's the difference between 25(OH)D and 1,25(OH)2D when it comes to the VDR? | Masterjohn Q&A Files #295
Short answer: 25(OH)D is 1000 times weaker at activating the VDR than 1,25(OH)D, but 1000 times more abundant. This is why I advocate measuring both, and ultimately believe we need to create a calculated index of "biological vitamin D activity" from them. This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access five other free samples using this link: https://chrismasterjohnphd.substack.com/p/questions-on-vitamin-d-fatty-liver In that batch of free episodes you will also find the answers to these questions: What's the difference between 25(OH)D and 1,25(OH)2D when it comes to the VDR? Reversing Fatty Liver: How Long Does It Take? What if my A1C says I'm diabetic but my CGM says I'm fine? Will reishi, turmeric, or curcumin tank my testosterone? The 3 Phases of Fasting: And How to Get Kicked Out of Each One If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up: https://chrismasterjohnphd.substack.com/qanda Learn more about the Masterpass here: https://chrismasterjohnphd.substack.com/about This snippet is from the April 13, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what's included: How to balance vitamins E and K What prenatal vitamin do I recommend? Why does my smoothie make my hands cold? What type of choline to use? Is there an interaction between glycine and aspirin? What supplements can be used in the fasting state? How to manage protein intake within a small eating window on an intermittent fasting regimen? Looking at a study on calcium alpha-ketoglutarate supplementation. Should I take vitamin D for COVID if I easily get hypercalcemia from it? What to do about nausea in pregnancy? Brief questions on restless legs, exercise during fasting, puffy eyes, and health effects of spicy foods. Here's a link to the full AMA: https://chrismasterjohnphd.substack.com/p/ask-me-anything-april-13-2022 Access the show notes, transcript, and comments here. Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Apr 18, 2022 • 1h 33min
Can Regenerative Agriculture Solve the Food Crisis?
Rising Food Prices Part 4: Can Regenerative Agriculture Solve the Food Crisis? This is the 4th in a series of interviews I am conducting to try to better understand why food prices have been rising, where they are going as we move toward a potential food crisis, how this will impact the evolving landscape of food availability, and what we should do about it. Allen Williams joins me to talk about conventional, organic, and regenerative agriculture, and how fuel and fertilizer inputs differ between them, and why regenerative agriculture offers the best resilience in the face of what looks like an emerging food crisis. Allen Williams is a 6th generation family farmer and founding partner of Grass Fed Insights, LLC, Understanding Ag, LLC and the Soil Health Academy. He has consulted with more than 4000 farmers and ranchers in the U.S., Canada, Mexico, South America, and other countries, on operations ranging from a few acres to over 1 million acres. Allen pioneered many of the early regenerative grazing protocols and forage finishing techniques and now teaches those practices and principles to farmers globally. He is a "recovering academic", having served 15 years on the faculty at Louisiana Tech University and Mississippi State University. He holds a B.S. and M.S. in Animal Science from Clemson University and a Ph.D. in Livestock Genetics from LSU. He has authored more than 400 scientific and popular press articles, and is an invited speaker at regional, national, and international conferences and symposia. Allen and his colleagues specialize in whole farm & ranch planning based on the concept of regenerative agriculture. Their approach creates significant "value add" and prepares the landowner for multiple enterprise/revenue stream opportunities that stack enterprises and acres. This approach allows for enhanced profitability and/or investment value. They routinely conduct workshops and seminars across the U.S., Canada, and Mexico. Find regenerative agriculture at https://regenified.com/ This is a work in progress. Until it is completed, use https://localharvest.org, https://eatwild.com, and https://soilhealthacademy.org/shop-regen-foods/ Follow Allen's work at https://understandingag.com/ Learn about soil at https://soilhealthacademy.org/ Find more research on the topic at https://www.ecdysis.bio/ If you are interested in investment opportunities in regenerative agriculture, inquire with Allen using the Understanding Ag contact form: https://understandingag.com/connect-with-us/ This series started from a Substack post I wrote, The Emerging Food Crisis: https://chrismasterjohnphd.substack.com/p/the-emerging-food-crisis Over the next month, as part of this series, I will conduct interviews and panel discussions on my podcast in an effort to better understand the issue and what to do about it. Relying primarily on interviews will allow me to better understand the issue while staying focused on finishing my vaccine research so I can ultimately return to finishing my book. I will eventually be concluding my work on the vaccines with a COVID Vaccine Guide, which I will distribute for free to paid Substack subscribers, those who have pre-ordered my Vitamins and Minerals 101 book, and members of the CMJ Masterpass. Articles in this series that lay out actionable foundations of my future protocol for vaccine side effects will be for paid Substack subscribers and Masterpass members. However, most of them will available for free for the first 48 hours, and all of them will be readable with a free trial. Paid Substack subscribers get immediate access to my COVID Guide, and are entitled to 50% off a membership to the Masterpass as well. You can subscribe or upgrade your subscription here: https://chrismasterjohnphd.substack.com/subscribe You can pre-order the book here: https://chrismasterjohnphd.com/book And you can join the Masterpass here: https://themasterpass.chrismasterjohnphd.com/sales-page Masterpass members get to watch these interviews live, and also have monthly access to a live Q&A with me. The next Q&A session is Wednesday, May 18, 12:00 PM Eastern. Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Apr 8, 2022 • 47min
Rising Food Prices Part 3: The Commodity Trade
Tony Greer joins me to talk about how lockdowns, politics, and the commodity trade contribute to rising food prices. Tony Greer is partly responsible for my awareness of the emerging food crisis as I had initially learned of Doomberg from him last year. He has been a macro trader for over thirty years, is a regular on the Real Vision Daily Briefing, and is editor of the Morning Navigator. Tony brings us unique insights as a trader who saw the rise in commodity prices early. Will the rotation out of tech stocks into commodities continue? What role does this trade have in amplifying food prices itself? Can we use technical signals from the market to gauge the likelihood this problem will get much worse, and to be able to spot light at the end of the tunnel when it finally emerges? Tony surprised me by suggesting the most important signal to look for as "light at the end of the tunnel" ushering in a reprieve from rising food prices is not so much a technical indicator from the charts or from economic data but rather a sustainable 180-degree reversal in the political hostility to the energy markets. He suggests food prices would take another 7 or more years to calm down once this reversal is sustained. None of this is financial advice and you must make your own decisions at your own risk. However, we conclude with some thoughts Tony has on how to keep savings safe in an environment like this. You can join his newsletter at https://tgmacro.com/ and follow him on Twitter at https://twitter.com/TgMacro This series started from a Substack post I wrote, The Emerging Food Crisis: https://chrismasterjohnphd.substack.com/p/the-emerging-food-crisis Over the next month, as part of this series, I will conduct interviews and panel discussions on my podcast in an effort to better understand the issue and what to do about it. Relying primarily on interviews will allow me to better understand the issue while staying focused on finishing my vaccine research so I can ultimately return to finishing my book. I will eventually be concluding my work on the vaccines with a COVID Vaccine Guide, which I will distribute for free to paid Substack subscribers, those who have pre-ordered my Vitamins and Minerals 101 book, and members of the CMJ Masterpass. Articles in this series that lay out actionable foundations of my future protocol for vaccine side effects will be for paid Substack subscribers and Masterpass members. However, most of them will available for free for the first 48 hours, and all of them will be readable with a free trial. Paid Substack subscribers get immediate access to my COVID Guide, and are entitled to 50% off a membership to the Masterpass as well. You can subscribe or upgrade your subscription here: https://chrismasterjohnphd.substack.com/subscribe You can pre-order the book here: https://chrismasterjohnphd.com/book And you can join the Masterpass here: https://themasterpass.chrismasterjohnphd.com/sales-page Masterpass members get to watch these interviews live, and also have monthly access to a live Q&A with me. The next Q&A session is Wednesday, April 13, 6:00 PM Eastern. Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Apr 6, 2022 • 1h 7min
Rising Food Prices Part 2: "Money Printing"
With Dr. Michael Howell, PhD. This is the second in a series of interviews I am conducting to try to better understand why food prices have been rising, where they are going as we move toward a potential food crisis, how this will impact the evolving landscape of food availability, and what we should do about it. Michael Howell, PhD joins me to discuss whether "money printing" and the liquidity cycle might be playing a role in rising food prices. Howell has a PhD in Economics and specializes in analyzing global central bank activities, liquidity trends, and capital flow data across 80 economies. He is CEO of CrossBorder Capital, which he founded in 1996. He developed the quantitative liquidity research methodology while he was Research Director at Salomon Bros. from 1986. He was subsequently appointed Head of Research at Baring Securities in 1992, and was top-ranked "Emerging Market Strategist" by institutional investors for the three years prior to setting up CrossBorder Capital. Michael has worked in financial markets since 1981 and is a regular international conference speaker. He is a qualified US Supervisory Analyst. You can buy his book, Capital Wars: The Rise of Global Liquidity, here. You can follow his company, Cross Border Capital, on Twitter here. This series started from a Substack post I wrote, The Emerging Food Crisis: https://chrismasterjohnphd.substack.com/p/the-emerging-food-crisis Over the next month, as part of this series, I will conduct interviews and panel discussions on my podcast in an effort to better understand the issue and what to do about it. Relying primarily on interviews will allow me to better understand the issue while staying focused on finishing my vaccine research so I can ultimately return to finishing my book. I will eventually be concluding my work on the vaccines with a COVID Vaccine Guide, which I will distribute for free to paid Substack subscribers, those who have pre-ordered my Vitamins and Minerals 101 book, and members of the CMJ Masterpass. Articles in this series that lay out actionable foundations of my future protocol for vaccine side effects will be for paid Substack subscribers and Masterpass members. However, most of them will available for free for the first 48 hours, and all of them will be readable with a free trial. Paid Substack subscribers get immediate access to my COVID Guide, and are entitled to 50% off a membership to the Masterpass as well. You can subscribe or upgrade your subscription here: https://chrismasterjohnphd.substack.com/subscribe You can pre-order the book here: https://chrismasterjohnphd.com/book And you can join the Masterpass here: https://themasterpass.chrismasterjohnphd.com/sales-page Masterpass members get to watch these interviews live, and also have monthly access to a live Q&A with me. The next Q&A session is Wednesday, April 13, 6:00 PM Eastern. Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Apr 2, 2022 • 1h 29min
Rising Food Prices Part 1: Oil and Fertilizer
This is the first in a series of interviews I am conducting to try to better understand why food prices have been rising, where they are going as we move toward a potential food crisis, how this will impact the evolving landscape of food availability, and what we should do about it. Josh Young and Tracy Schuchart are here to talk about why oil and fertilizer are in short supply and why their prices have been steadily rising. Josh Young is Chief Investment Officer and Founder of Bison Interests, which invests in the publicly traded oil and gas markets. Follow him on Twitter at https://twitter.com/Josh_Young_1 Tracy Shuchart is Partner and Global Macro Energy and Materials Strategist at Intelligence Quarterly. Follow her on Twitter at https://twitter.com/chigrl This series started from a Substack post I wrote, The Emerging Food Crisis: https://chrismasterjohnphd.substack.com/p/the-emerging-food-crisis Over the next month, as part of this series, I will conduct interviews and panel discussions on my podcast in an effort to better understand the issue and what to do about it. Relying primarily on interviews will allow me to better understand the issue while staying focused on finishing my vaccine research so I can ultimately return to finishing my book. I will eventually be concluding my work on the vaccines with a COVID Vaccine Guide, which I will distribute for free to paid Substack subscribers, those who have pre-ordered my Vitamins and Minerals 101 book, and members of the CMJ Masterpass. Articles in this series that lay out actionable foundations of my future protocol for vaccine side effects will be for paid Substack subscribers and Masterpass members. However, most of them will available for free for the first 48 hours, and all of them will be readable with a free trial. Paid Substack subscribers get immediate access to my COVID Guide, and are entitled to 50% off a membership to the Masterpass as well. You can subscribe or upgrade your subscription here: https://chrismasterjohnphd.substack.com/subscribe Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Mar 30, 2022 • 55min
The Spike Protein As a Pore-Forming Toxin
The spike protein pokes holes in cell membranes at concentrations much lower than those achieved with vaccination, contributing to COVID-like illness and mitochondrial damage. But is the J&J immune? This is not medical advice. This podcast was originally published in written form as a Substack article, fully referenced, found here: https://chrismasterjohnphd.substack.com/p/the-spike-protein-as-a-pore-forming This is the first in a series of posts in which I will outline the potential mechanisms of spike protein toxicity and vaccine side effects and brainstorm actionable steps vaccinees can take to protect against these effects or heal from them. I will eventually be concluding my work on the vaccines with a COVID Vaccine Guide, which I will distribute for free to paid Substack subscribers, those who have pre-ordered my Vitamins and Minerals 101 book, and members of the CMJ Masterpass. Articles in this series that lay out actionable foundations of my future protocol for vaccine side effects will be for paid Substack subscribers and Masterpass members. However, most of them will available for free for the first 48 hours, and all of them will be readable with a free trial. Paid Substack subscribers get immediate access to my COVID Guide, and are entitled to 50% off a membership to the Masterpass as well. You can subscribe or upgrade your subscription here: https://chrismasterjohnphd.substack.com/subscribe Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Mar 29, 2022 • 34min
The Emerging Food Crisis
My tentative view on what is causing it and what to do about it. This is NOT caused primarily by the conflict in Ukraine and a sudden peaceful solution to the conflict will not avert it. The written version with links to sources can be found here: https://chrismasterjohnphd.substack.com/p/the-emerging-food-crisis Please Show The Substack Post Some Love Please hit up the Substack post and let me know what you think in the comments! And please like the post if you found it valuable, and share the post with others if you believe they too would find it valuable. Subscribe or Upgrade I will eventually be concluding my work on the vaccines with a COVID Vaccine Guide, which I will distribute for free to paid Substack subscribers, those who have pre-ordered my Vitamins and Minerals 101 book, and members of the CMJ Masterpass. Articles in this series that lay out actionable foundations of my future protocol for vaccine side effects will be for paid Substack subscribers and Masterpass members. However, most of them will available for free for the first 48 hours, and all of them will be readable with a free trial. Paid Substack subscribers get immediate access to my COVID Guide, and are entitled to 50% off a membership to the Masterpass as well. You can subscribe or upgrade your subscription here: https://chrismasterjohnphd.substack.com/subscribe Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Mar 4, 2022 • 1h 18min
Explaining the "Hospitalization Paradox"
https://chrismasterjohnphd.com/paradox Please subscribe to my Substack at https://chrismasterjohnphd.substack.com Subscription is completely free but if you take the option to pay $5 a month or $30 per year, you will get access to exclusive content, as well as my COVID guide for free and 50% off my Masterpass membership program. Please like, comment on, and share the Substack version of this post. This will help spread it far and wide, as subscriber engagement drives the Substack algorithm. Engagements from paid subscribers count the most, but engagements from free subscribers come in the highest numbers and are the foundation for spreading the content. This episode covers how a negative PCR test can serve as a marker for systemic inflammation and spike protein toxicity, creating a widely exploited statistical anomaly to make misleading claims about hospitalization. I consider this the absolute most important topic of our decade: the core anomaly in COVID data that is exploited worldwide to claim the vaccines are protecting against hospitalization among those who get COVID, yet which is at complete odds with the CDC data showing the majority of people hospitalized for COVID-like illness are vaccinated and that the vast majority of them test negative. "COVID-like illness" refers to the signs and symptoms of COVID, regardless of the results of a PCR test. While the clinical fate of PCR-negative COVID-like illness is completely unclear, we cannot just ignore it. In fact, recent evidence suggests that as much as 69% of PCR-negative COVID-like illness might be genuine COVID. Zooming out to capture the total COVID-like illlness, the "Hospitalization Paradox" refers to the fact that the vaccines do not protect against it at all. When the vaccines have high efficacy against a negative test, all they do is make ill people test negative. In contexts where they have sub-par efficacy against a negative test — the Johnson and Johnson trial, after 3 months of being vaccinated with no booster, and in the face of increasingly vaccine-resistant variants like delta and omicron — suddenly they appear to have efficacy against hospitalization, but only among vaccinated people who test positive. The vaccinated people who test negative, by contrast, wind up in the hospital with PCR-negative COVID-like illness. In this very extensively documented article, I argue that this can be explained by the negative test, during the waning phase, becoming a marker of vaccine-induced systemic inflammation and the persistence of spike protein in the body, contributing to acute and cumulative spike protein toxicity and possibly spike-induced autoimmunity. Read the article here: https://chrismasterjohnphd.com/paradox Please subscribe to my Substack at https://chrismasterjohnphd.substack.com Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.

Jan 30, 2022 • 20min
I'm About to Get Deplatformed
I'm recording from "Youtube Jail," where I'll be until Monday morning. Two more strikes and I'm out. Please help our community stay connected by joining my email list at https://chrismasterjohnphd.com/uncensored Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


