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Master One Thing - Rapamycin Longevity Series

Latest episodes

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Jan 17, 2024 • 1h 22min

Joan Mannick on Rapamycin Longevity Series | Turning down mTOR to young levels may be good for aging

Dr Joan Mannick is one of the world’s leading rapamycin and mTOR researchers in the longevity field. Joan has a background in academic medicine and is currently CEO at her own company Tornado Therapeutics where they focus on developing the next generation of mTOR inhibitors. One of the company goals is to create a mTOR inhibitor which is better than Rapamycin. Throughout the years Joan has made important discoveries in humans when it comes to finding a connection between mTOR inhibition and improvement of the aging immune system. In this podcast we are going to talk about her research, drug development, mTOR, rapamycin, rapalogs and other interesting longevity topics.Linkshttps://www.tornado-tx.comJoan's LinkedInJoan’s research publicationsBig thanks to TimePie for the research help for this episodeRapamycin resourcesRapamycin.newsRapamycin Facebook groupRapamycin Reddit groupConnect with Krister on:TwitterLinkedInInstagramDisclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
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Oct 17, 2023 • 1h 11min

Brian Kennedy on Rapamycin Master Series | Aging is the biggest risk factor for age-related diseases

Leading researcher Brian Kennedy discusses his extensive longevity research experience, his involvement in longevity companies, and his current longevity research project in Singapore. Topics include early discoveries in longevity research, the significance of the TORE pathway in nutrient signaling and longevity, the efficacy of NAD precursors, plans for the Rapa Mysen trial, exploring rapamycin derivatives, and the debate surrounding high protein vs low protein intake.
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Aug 22, 2023 • 1h 42min

Mikhail Blagosklonny on Rapamycin Longevity Series | mTOR drives age-related diseases

The world's leading Rapamycin researcher Mikhail Blagosklonny has a long background in cancer research and one important discovery he made around 2000 was that Rapamycin slowed down senescent cancer cells in different ways. After that step by step his interest in the longevity field increased and he developed the very interesting hyperfunction theory of aging. He has made a huge contribution in moving the Rapamycin longevity field forward and his research papers have impacted many people. For example, the Rapamycin physician Alan Green who thanks to these papers took the decision in 2017 to start prescribing Rapamycin off label. Today Alan Green has the biggest clinical experience in the area with more than 1200 patients. A lot of other physicians have after that also taken these steps and one of those are for example physician Peter Attia.LinksMikhail's research publicationsMikhail's twitterHomepageRapamycin resourcesRapamycin.newsRapamycin Facebook groupRapamycin Reddit groupConnect with Krister on:TwitterLinkedInInstagramDisclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
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Jul 11, 2023 • 1h 16min

Brad Stanfield on Rapamycin Longevity Series | Rapamycin, mTOR and the importance of muscle in life

Dr Brad Stanfield works as a medical doctor in New Zealand and beside his work in primary-care he has his own Youtube channel, in which he goes through the latest research and clinical guidelines on preventative medicine and longevity. In today’s podcast we are going to talk about Brad’s upcoming Rapamycin trial, the importance of muscle when we get older, sarcopenia and lots of other interesting longevity topics.LinksBrad Stanfield's YoutubeDonate to Brad's Rapamycin clinical trialBrad's MicroVitamin supplementBrad's twitterRapamycin resourcesRapamycin.newsRapamycin Facebook groupRapamycin Reddit groupConnect with Krister onTwitterLinkedInInstagramDisclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
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Jun 14, 2023 • 1h 8min

Pankaj Kapahi on Rapamycin Longevity Series | There is no one size longevity intervention that fits all

Professor Pankaj Kapahi has his own lab at the Buck Institute for Research on Aging. His research for two decades has been focusing on things such as dietary restriction, fasting, rapamycin, nutrition and longevity. Pankaj was one of the pioneer researchers who discovered in the beginning of 2000 that genetic inhibition of mTOR led to life extension in flies. In this podcast we are going to talk about that discovery, Rapamycin, calorie restriction and other interesting longevity topics.LinksKapahi's Lab at Buck InstituteJuvify and GLYLOPankaj's twitterRapamycin resourcesRapamycin.newsRapamycin Facebook groupRapamycin Reddit groupConnect with Krister on:TwitterLinkedInInstagramDisclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
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May 15, 2023 • 2h 29min

Matt Kaeberlein on Rapamycin Longevity Series | Lessons learned from two decades of Rapamycin research

Matt Kaeberlein, a leading Rapamycin researcher, discusses insights on mTOR, longevity, immune modulation, Dog Aging Project, effects on aging hallmarks, side effects of interventions, biomarkers for health assessment, personal experimentation, and future of longevity research.
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Apr 11, 2023 • 1h 23min

Alan Green on Rapamycin Longevity Series | Lessons learned from over 1200 patients

Dr Alan Green has his own medical practice in New York which focuses on longevity. He is a Rapamycin pioneer and one of the important longevity leaders who has made a big contribution to the longevity field and especially regarding the compound Rapamycin. Today he has clinical experience of more than 1200 patients who take Rapamycin and in this podcast he will share the knowledge he has acquired in the field.Contact information for Dr Alan Green's medical practice can be found herehttps://rapamycintherapy.comRapamycin resourcesRapamycin.newsRapamycin Facebook groupRapamycin Reddit groupConnect with Krister onTwitterLinkedInInstagramDisclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
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23 snips
Mar 15, 2023 • 50min

Ross Pelton on Rapamycin Longevity Series | How it all began

Ross Pelton, a knowledgeable pharmacist and author of 12 health books, shares intriguing insights on the longevity effects of Rapamycin. He delves into its remarkable transformation from an antifungal agent to a game-changer for organ transplant patients. The discussion unveils groundbreaking human trials showcasing Rapamycin's potential in enhancing immune function, especially in the elderly. Pelton also emphasizes the synergy between Rapamycin, fasting, and gut health, advocating for holistic lifestyle practices to promote well-being and longevity.

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