Master One Thing - Rapamycin Longevity Series

Brian Kennedy on Rapamycin Master Series | Aging is the biggest risk factor for age-related diseases

Oct 17, 2023

Leading researcher Brian Kennedy discusses his extensive longevity research experience, his involvement in longevity companies, and his current longevity research project in Singapore. Topics include early discoveries in longevity research, the significance of the TORE pathway in nutrient signaling and longevity, the efficacy of NAD precursors, plans for the Rapa Mysen trial, exploring rapamycin derivatives, and the debate surrounding high protein vs low protein intake.

01:11:04

Episode guests

Brian Kennedy

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Episode notes

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Quick takeaways

Promising longevity interventions include rapamycin, AKG, and rejuvenation studies with senescent cell clearance showing great potential.

Personalized approaches to longevity interventions are crucial for better outcomes based on individual characteristics and genetic profiles.

Engaging in research, increasing academic funding, and prioritizing stress management are key to advancing longevity and healthy aging.

Deep dives

Promising Longevity Interventions

Promising longevity interventions for humans include rapamycin, AKG, and rejuvenation studies. Rapamycin is considered a gold standard with proven efficacy. AKG supplementation has shown positive effects on health span and longevity in animal and human studies. Rejuvenation therapies, particularly for senescent cell clearance, show great potential for improving overall health and aging outcomes.

Introduction

2min

Early Days and Discoveries in Longevity Research

5min

Exploring the TORE pathway and its role in nutrient signaling and longevity

27min

Exploring NAD Precursors and their Efficacy

15min

Plans for the Rapa Mysen trial and considerations for the study population

2min

Exploring Rapamycin Derivatives and Other Ways to Inhibit mtorc

3min

High Protein vs Low Protein

16min

Professor Brian Kennedy from the National University of Singapore is one of the world's leading researchers in the longevity field and has done longevity research for more than two decades. He is active in many different longevity companies and has been the President and CEO at Buck Institute for Research on Aging. Throughout the years he has made many different important and revolutionary longevity discoveries. Currently he is also one of the persons who is trying to move the longevity forward in a much efficient and faster way. This work he is doing in Singapore where he is leading a huge longevity research project. This unique project is something we are going to talk about in the podcast. We will also talk about his research on Rapamycin and other interesting longevity topics.

Links

The centre for Healthy Longevity at the National University of Singapore

Healthy Longevity webinars on Youtube

Brian's research publications

Brian's Twitter

Brian's LinkedIn

Rapamycin resources

Rapamycin.news

Rapamycin Facebook group

Rapamycin Reddit group

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Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.

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