Master One Thing - Rapamycin Longevity Series cover image

Master One Thing - Rapamycin Longevity Series

Ross Pelton on Rapamycin Longevity Series | How it all began

Mar 15, 2023
Ross Pelton, a knowledgeable pharmacist and author of 12 health books, shares intriguing insights on the longevity effects of Rapamycin. He delves into its remarkable transformation from an antifungal agent to a game-changer for organ transplant patients. The discussion unveils groundbreaking human trials showcasing Rapamycin's potential in enhancing immune function, especially in the elderly. Pelton also emphasizes the synergy between Rapamycin, fasting, and gut health, advocating for holistic lifestyle practices to promote well-being and longevity.
50:18

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Rapamycin, originally studied for antibiotic use, is now recognized for its potential in promoting longevity through mTOR inhibition and enhanced autophagy.
  • The effectiveness of rapamycin in older adults' immune response emphasizes the importance of research on personalized dosing for longevity benefits.

Deep dives

Discovery and Function of Rapamycin

Rapamycin is a natural compound derived from soil bacteria found on Easter Island, initially studied for its antibiotic properties. After discovering its immune-suppressing qualities, it became FDA approved for kidney transplant patients to prevent organ rejection. This unique compound functions differently than traditional chemotherapy; instead of being cytotoxic, which damages healthy cells, it is cytostatic, stopping cancer growth without the collateral damage typically associated with chemotherapy. This has led researchers to explore its potential as a life extension drug, marking rapamycin as a significant breakthrough in anti-aging science.

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