Bloody Minded

Explore the curious case of thrombocytosis, where having too many platelets can cause more problems than they solve. Delve into the biology of platelet production and how misleading lab results can complicate diagnoses. Discover the connection between iron deficiency and elevated platelet counts, alongside the role of cytokines and bone marrow issues. Learn about the implications of thrombocytosis and why identifying underlying causes matters. Join a lighthearted yet informative journey into a complex medical phenomenon!

Dive into the fascinating world of thrombocytopenia, where platelets take center stage. Discover the surprisingly historical connection between platelets and gold! Learn about the various causes of low platelet counts, from dilution to autoimmune disorders. The discussion covers crucial evaluation techniques, management strategies, and platelet transfusion guidelines. With a mix of humor and serious insights, this exploration sheds light on an often-overlooked medical condition, stressing the importance of accurate diagnosis and tailored patient care.

Dive into the world of erythrocytosis, where too many red blood cells can be as problematic as too few! Discover the difference between primary and secondary causes, and hear about unique symptoms like aquagenic pruritus. The discussion includes the role of crucial lab tests and genetic markers, including JAK2 and EPO levels. Real-life case studies illuminate diagnostic challenges. Plus, get insights into the management of conditions like Polycythemia Vera and Budd-Chiari Syndrome, stressing the importance of comprehensive history and testing in treatment!

Uncover the mysteries of anemia in a lively discussion! Explore the importance of blood cell counts, and learn about various types of anemia, including microcytic and macrocytic cases. Delve into thalassemia, iron deficiency, and even lead poisoning with a humorous twist. The hosts simplify complex concepts, making them accessible for medical novices. Plus, discover surprising links between anemia and lifestyle factors like diet and drug use. This enjoyable blend of education and entertainment is sure to make hematology engaging!

Mitchell Rawlings, a senior morphologist and hematology expert at Royal North Shore Hospital, dives into the fascinating world of blood counts. He demystifies the process of counting cells and explains automated analysers' magic. Listeners will learn about the journey of a full blood count from vein to screen, the significance of acronyms, and the importance of quality control in the lab. Mitch also sheds light on common errors in blood sampling and emphasizes that the lab isn't out to get you! It's an insightful exploration for anyone curious about hematology.

Dr. Alison Chandler, a seasoned haematologist, shares her expertise on handling common hematology consults. She offers practical tips to ease the stress of consultations, especially for thrombosis and coagulation challenges. With a blend of humor and real-life anecdotes, Alison emphasizes the importance of effective communication and detailed patient history. Listeners will appreciate insights into managing acute conditions like pulmonary embolism and understanding the dynamics of platelet counts post-surgery. Ready to step out of that toilet now?

Bashar was tasked with finding an expert to talk to about blood banking. He decided to cold-email the best transfusion-educator in the world who is probably responsible for hundreds if not thousands of haematology trainees understanding blood banking. Turns out he's an absolutely lovely guy who decided to spend an hour of his Monday morning chatting to us about podcasting, education, IgA deficiency and all the wonderful aspects of the blood bank. Join us for an hour with Dr Joe Chaffin MD, much more widely known as "The Blood Bank Guy".For more of Dr Chaffin's excellent work, check out www.bbguy.org & The Blood Bank Guy Essentials Podcast wherever you get your podcastsTimestamps1:00 - Containing our excitement3:38 - The Joe Chaffin story8:15 - Getting into education17:40 - Surprising moments in podcasting22:45 - How to improve transfusion teaching27:50 - The Blood Bank/Clinician interface38:31 - What scares the Blood Bank Guy?46:42 - The future of blood banking49:53 - What to unlearn57:19 - TA-GVH made easy1:01:24 - Final words of wisdomSupport the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Dive into the fascinating world of apheresis, where blood components are transformed for better medical use. Discover how ancient practices trace back to Hippocrates while modern machines perform plasma exchange. Engage with the complexities of patient consent and potential complications, including citrate toxicity. The hosts blend humor and insight as they explore the procedure’s significance in treating conditions like sickle cell disease. Uncover the magic of separating blood into its components and the clinical guidelines that make it all possible.

Join our visiting expert Dr Eoghan Molloy - Multitalented transfusion medicine specialist and consultant haematologist at Cork University Hospital to teach us how to cross the ABO Rubicon and provide transfusion support in ABO mismatched transplantation. Visit the lab and see what happens to the forward and reverse group when you're in the middle of changing groups. Brush up on your major, minor and bidirectional mismatches as the generally mismatched Bloody Minded Crew learn from a real expert again. PS Nick had his microphone set to ASMR so there are a few hiccups in the audio quality but the content was too good to missTimestamps:0:59 - Nick's real overseas friend2:52 - Intro to Dr Eoghan Molloy9:10 - ABO incompatibilities in transplant15:19 - Graft manipulation17:47 - Patient preparation in ABO mismatch20:44 - Provision of blood products in transplant32:51 - Red cell aplasia in transplant38:16 - Passenger lymphocyte syndrome40:37 - CMV in transplant46:06 - Irradiated products52:12 - Clinical case and wrap upSupport the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Dive into the world of complex hematology with a lighthearted twist! Explore the quirky MAIPA test that combines four antibodies in one test, alongside amusing food analogies. Uncover the intricacies of fetal and neonatal alloimmune thrombocytopenia (FNAIT) and the clinical strategies for managing it. Get insights on the essential collaboration between hematology and neonatal teams, plus the challenges of treating immune thrombocytopenic purpura during pregnancy and optimizing transfusion protocols. It's educational and entertaining!