Conan chats with an escape room Game Master about various escape room themes and player dynamics, creativity in show business-related projects, Dungeons and Dragons adventures, and the humorous tale of Filonius Stumpleton. They also touch on time management, therapy benefits, and online therapy services.

Zach Woods discusses why being smart is overrated, his new animated series, getting hooked on jazz, and unintentional oversharing with Conan. Plus, a hilarious arm-wrestling contest and banter between the two friends.

Businesswoman Melinda French Gates talks about her journey into computer science, philanthropy, and importance of education. The podcast also includes discussions on Gates Foundation letters, planning a Carnival Cruise Line vacation, prioritizing well-being, and empowering children in wealthy environments.

Conan O'Brien and Chelsea Peretti discuss comedy influences, surviving a bear attack, and the evolution of podcasting. They share funny stories from a comedy festival, talk about missed opportunities with celebrities, and give humorous tips for dealing with bear encounters.

Conan chats with a children's librarian about dark themes in kids' books and fairy tale roles. They discuss humorous riddles, offer to buy a drink, and explore the importance of play for kids.

Adam Sandler joins Conan O'Brien to discuss meeting celebrities, winning the Mark Twain Prize, warm comedians, and his new film. Conan shares a mistaken identity airport story. The conversation is light-hearted, funny, and full of friendship banter.

Discover how a woman behind Benedict Arnold's betrayal influenced history, explore Arnold's determination to betray America, and witness Peggy's loyalty amidst growing suspicions of treason in this intriguing podcast episode

Conan chats with Steven about astrology-inspired jewelry, the power of objects, and intentional living. They discuss designing unique pieces, T-Mobile SONA, and the conflicting desires of material possessions.

Actress Tracee Ellis Ross chats with Conan O’Brien about her childhood characters, turning criticism into fuel, and more. Conan also deals with a hairstyling-related scheduling dispute with his team.

Conan helps a team member with dating app profiles, discusses favorite dating apps and superpowers, and gives advice on creating a fun bio. They also joke about a persistent Conan memorabilia request, celibacy, and yoga for finding a partner.