This Week in Virology

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guests: Ethan Jackson and Jonathan Carlson Project Premonition, a Microsoft Research project that uses drones to capture mosquitoes and analyze them for pathogens, preprint servers, and three mouse models for Zika virus induced birth defects are the topics of this episode hosted by the TWiumvirate and theirs guests Ethan and Jonathan. Links for this episode Project Premonition Premonition feasibility study in Grenada Zika virus causes microcephaly in mice (Cell Stem Cell) Brazilian Zika virus causes defects in experimental models (Nature) Zika virus causes placental damage and fetal demise in mice (Cell) Letters read on TWiV 390 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Also brought to you by ASV 2016 Weekly Science Picks Dickson - Germany nearly reached 100% renewable power Alan - Vertical City documentary and Lumino City gameRich - Errol Morris: 'Demon in the Freezer' Kathy - Entropic Time YouTube by A Capella Science (watch "the making of")Vincent - Agar Art contest finalists Listener Picks Jennie - SciFi reading (scroll down) Send your virology questions and comments to twiv@microbe.tv

Host: Vincent Racaniello Guest: Stan Lemon Vincent speaks with Stan Lemon about his career in virology, from early work on Epstein Barr virus, through making essential discoveries about hepatitis A virus, hepatitis C virus, and rhinoviruses. Links for this episode Live in Edmonton, Eh? (TWiV 235) Replication of EBV in epithelial cells (Nature) Returning to Carolina after 14 years Evolutionary origins of hepatitis A virus (TWiV 265) cre in rhinovirus genome (RNA) Naked viruses that aren't always naked (Ann Rev Virol) miR-122 and hepatitis C virus RNA (Cell Host Micr) This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Preprint servers, the structure of an antibody bound to Zika virus, blocking Zika virus replication in mosquitoes with Wolbachia, and killing carp in Australia with a herpesvirus are topics of this episode hosted by Vincent, Dickson, Alan, and Kathy. Links for this episode biorXiv preprint server Please review Vaccines and Your Child Structure of antibody bound to Zika virus E protein (Cell Host Microbe) Wolbachia blocks Zika virus in mosquitoes (Cell Host Microbe) Zimmer on Wolbachia and Zika virus (NY Times) Fauci on Zika virus vaccine (Science) Carpageddon (The Conversation) Letters read on TWiV 388 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Also brought to you by ASV 2016 Weekly Science Picks Dickson - EarthEnv Alan - Research funding by lottery Kathy - Eugenia Cheng Math and BakingVincent - Zika Diaries Listener Picks Stephen - Virus trading cards William - Virus trading cards Norma+Maurice - Virus trading cards Tom - Virus trading cards Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Nina Martin Nina Martin joins the TWiV team to talk about the movie Vaxxed, her bout with dengue fever, and the latest research on Zika virus. Links for this episode Public Health United Fifty Shades of Science (TEDx) Parents convicted in death of toddler (Science Based Medicine) CDC: Zika virus causes microcephaly (NEJM) Dengue virus antibodies enhance Zika virus infection (biorXiv) Zika virus in Brazilian nonhuman primates (biorXiv) Zika virus IgM in CSF of microcephalic babies (Lancet) Brain organoids for modeling Zika virus infection (Cell) Letters read on TWiV 387 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Also brought to you by ASV 2016 Weekly Science Picks Nina - Vaccines and Your Child by Paul Offit and Charlotte MoserDickson - The animals of Chernobyl Alan - Five rules of lab safety Kathy - 20 best science images of the year?Vincent - Massive undersea crab swarm Listener Picks JP - Global map of wind Todd - Doc Martin Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Ted Diehl and Welkin Johnson Ted and Welkin inform the TWiV team how the evolution of ancient retroviruses can be inferred by studying their sequences in the genomes of modern mammals, and join in a discussion of virus dispersal during different methods for drying hands. Links for this episode More fun than a monkey full of viruses (TWiV 122) Tracking ancient retrovirus evolution in mammals (eLife) Virus dispersal during hand drying (J Appl Micro) More than you wanted to know about hand drying (one, two, three, four, five, six) This episode is sponsored by ASM Agar Art Contest, ASM Grant Writing Course, and ASV 2016 Weekly Science Picks 1:30:20 Welkin - Lab Girl by Hope Jahren (essay)Ted - Accidental brilliance in scienceRich - Perpetual motion?Kathy - R0 graphic and explanationVincent - NWS ditches all caps forecasts Listener Picks Basel - Gimli Glider and Mars Climate OrbiterKen - Vaccination comic book Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello and Dickson Despommier Guest: Stuart Firestein Stuart joins Vincent and Dickson to talk about his sequel to Ignorance, a book called Failure, which seeks to make science more appealing by revealing its faults. Links for this episode Stuart Firestein's site Ignorance with Stuart Firestein (TWiV Special) The pursuit of ignorance (TED) Ignorance by Stuart Firestein Failure by Stuart Firestein This episode is sponsored by ASM Agar Art Contest and ASV 2016 Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Rich Condit Guests: Nischay Mishra and Ian Lipkin Nischay and Ian join the TWiVions to discuss mass die-offs of tilapia by a novel orthomyxo-like virus, Ian's editorial on the movie Vaxxed, and new vaccines to prevent dengue virus infections, including a human challenge model. Links for this episode Novel orthomyxo-like virus in Tilapia die-offs (mBio) Fish flu (TWiV 41) Anti-vaccination lunacy won't stop (WSJ) Single-dose dengue vaccine effective (J Inf Dis) Dengue vaccine needs (J Inf Dis) Composition of TV003 (J Inf Dis) Dengue vaccine mutagenesis (Curr Top Micr Imm) Dengue human challenge model (Sci Transl Med) Yellow fever alarm (STAT) Experiment: Zika virus UC Berkeley Microbiology Student Symposium Image credit Letters read on TWiV 384 This episode is sponsored by ASM Agar Art Contest, ASM Grant Writing Course, and ASV 2016 Weekly Science Picks Rich - Dune by Frank HerbertAlan - Adult vaccination video contestDickson - Ski town greenhouseVincent - Preprint servers: Force awakens or revenge of undead? Listener Picks Ken - Golden Mole Awards for Accidental Brilliance (list, video)Jim - Linear algebra course Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Kathy Spindler Guest: Esper Kallas Esper and the Merry TWiXters analyze the latest data on Zika virus and microcephaly in Brazil, and discuss publications on a mouse model for disease, infection of a fetus, mosquito vector competence, and the cryo-EM structure of the virus particle. Links for this episode Zika virus in the Americas (Science) Co-circulation of dengue, Zika, chik in Brazil (Medicine) Murine model for Zika virus infection (Am J Trop Med Hyg) Zika virus susceptibility of A. aegypti and A. albopictus (PLoS NTD) Infectious Zika virus from saliva (EuroSurveill) Zika virus spread through saliva? (Braz Oral Res) Five Zika virus reviews (one, two, three, four, five) Zika virus and microcephaly, Brazil (MMWR) Zika virus in urine (EuroSurveill) Zika virus infection of fetus (NEJM) Real-time sharing of Zika virus data (JAMA) Image credit: Richard Kuhn Letters read on TWiV 383 This episode is sponsored by ASM Agar Art Contest and ASV 2016 Weekly Science Picks Esper - The Chaos by Gérard Nolst Trenité and HIV pathogenesis courseAlan - Science KombatDickson - Four steps to wiping out a mosquitoVincent - Public lacks information on Zika virusKathy - Zika virus cryo-EM structure video Listener Picks Justin - Culture-independent discovery of Archaeal virusMelinda - Zika virus open research portal and Your body battles series Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Kathy Spindler Guests: Nels Elde and Edward Chuong Nels and Ed join the TWiV team to talk about their observation that regulation of the human interferon response depends on regulatory sequences that were co-opted millions of years ago from endogenous retroviruses. Links for this episode Endogenous retroviruses and regulation of innate immunity (Science) Placenta is viral (Nature) An ERV that maintains pluripotency of human embryonic stem cells (TWiV 279) Letters read on TWiV 382 This episode is sponsored by ASM Agar Art Contest and ASV 2016 Weekly Science Picks Nels - Don't Get Me Started - Matt GiorgianniAlan - Sun's magnetic field (paper)Dickson - Most realistic dinosaur terrifiesVincent - Top secret!Kathy - Zika virus risk for US 50 cities (paper)Ed - Watching comb jellies poop Listener Picks Asal - Lost paper of Gregor MendelDennis - PhysicsGirlJacob - Second (XKCD) and ACI blogger interview Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guest: Carl Zimmer Carl Zimmer joins the TWiV team to talk about his career in science writing, the real meaning of copy-paste, science publishing, the value of Twitter, preprint servers, his thoughts on science outreach, and much more. Links for this episode Carlzimmer.com All Carl's articles at NYTimes Carl at Stat The Loom Staying afloat in the rising tide of science (Cell) Parasite Rex Planet of Viruses Handful of biologists went rogue (NYTimes) This episode is sponsored by ASV 2016 and ASM Agar Art Contest Weekly Science Picks Carl - Surprising benefit of viral DNAAlan - Global ship trafficDickson - Music with 2000 marblesVincent - The whiteboard revolutionKathy - How to interpret UK and American advisorsRich - Carina Storrs, science writer Send your virology questions and comments to twiv@microbe.tv