This Week in Virology

The TWiV hosts present two potentially seminal papers, on long-distance chemoattraction of a host by a chlorovirus, and replication of a nanovirus across multiple cells in a plant. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Paul Has Measles now in German (virology blog) Chloroviruses lure hosts (J Virol) Multicellular replication in plants (eLife) Image credit Letters read on TWiV 539 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - Why Do So Many Scientists Want to be Filmmakers Alan- Better boarding method airlines won't use Dickson- Mass timber building Kathy- What organisms to study flow chart Vincent - World Pulls Andon Cord on 737 MAX Listener Pick Richard- The Real Cost of Knowledge Islam- 200 icosahedral viruses poster Mike- Post-Doc Me Now Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

TWiV travels to the University of Iowa to speak with Wendy Maury and Stanley Perlman about their research on Ebolavirus entry and coronavirus pathogenesis. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Wendy Mauryand Stanley Perlman Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TIM-1 is receptorfor Ebolaviruses (Proc Natl Acad Sci) TIM-1 is receptor for Lassa virus (J Virol) SARS coronavirus causes neuronal death (J Virol) T cells and IL-10 in viral demyelination (J Neuroimmunol) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The Scholars of the Podcast reveal ribosomal proteins encoded in viral genomes, and a protein cell receptor for bat influenza viruses. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed Roald Dahl endorses measles vaccine Viruses encode ribosomal proteins (Nat Commun) Bat influenza virus receptor (Nature) Going to bat for flu research (TWiV 173) Letters read on TWiV 537 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - Yes, I'm a Scientist on Twitter. Stop Judging Me. Alan- Impact of vaccines, graphed in heat maps Dickson- Treehoppers Kathy- World watershed maps Rich- Gene Machine by Venki Ramakrishnan Vincent - House hearing on measles outbreak (ASM comment) Listener Pick Jordan- Facebook may remove anti-vaccine recommendations Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Vincent and Alan travel to Tufts Veterinary School where they meet up with members of the Runstadler lab to talk about their work on influenza virus circulation in water birds and seals. Hosts: Vincent Racaniello and Alan Dove Guests: Jonathan Runstadler, Nichola Hill, Wendy Puryear, and Kate Sawatzki Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Cummings School of Veterinary Medicine Influenza virus in North Atlantic grey seals (Emerg Microbes infect) Influenza viruses in Alaskan wild birds (Emerg Inf Dis) Wild bird influenza virus replication in human cells (Infect Genet Evol) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiV team discuss the use of quantum dots to study uncoating of influenza virus in real time, and induction of endothelial dysfunction by flavivirus NS1 proteins in a tissue-specific manner. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed Quantum dots to visualize influenza entry (PNAS) Quantum dots (Wikipedia) Flavivirus NS1 triggers endothelial dysfunction (Cell Rep) Image credit Letters read on TWiV 535 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - Hotel Influenza Alan- Your town's climate in 60 years Dickson- BMC Research in Progress Photo Competition Rich- NASA's Opportunity Rover Mission on Mars Ends (landing animation) Vincent - Watch a single cell become a complex organism in six minutes Listener Pick Anne- Pathogenesis II Kickstarter Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA. Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed Calicivirus portal visualized (Nature) Calicivirus portal - long version (biorXiv) m6A modification and innate response (Nat Immunol) Brianne Barker's immunology course m6A modification and innate response (Genes Dev) Letters read on TWiV 534 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - The Red Queen's Race Card Game Alan- Pentax Papilio II Dickson- Felice Frankel on improving visual side of science Kathy- History of the alphabet chart (free download) usefulcharts.com (see blog, such as Latin Greek Cyrillic Venn Diagram) Vincent - Virology Lectures 2019 Listener Pick Peter- Microbehunter (YouTube, blog, forum) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiVosophers review the Chinese plasma virome revealed by non-invasive prenatal testing, and a new filovirus genome from bats in China. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV 2019 European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed Jerard Hurwitz age 90 RIP Paul has Measles now in French (virology blog) Chinese plasma virome (Cell) Blood virome of 8000 humans (TWiV 435) Měnglà filovirus from bats in China (Nat Microbiol) How to write a virus name (ICTV) Ortervirales (J Virol) Virologists oppose new definition of virus species (Arch Virol) Ebola sitrep (WHO) Letters read on TWiV 533 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - Trying Polar Vortex Experiments at Home Rich- Three Identical Strangers Kathy- Science wear, especially for Valentine's Day (discount) Vincent - State of anti-vaccine movement in US and Top 10 Health Threats for 2019 Listener Pick Amy- If government can't deliver safe vaccines, is it fit to rule? Ted- Understanding Economics of Microbial Threats (pdf) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiVers discuss the spread of African swine fever virus and its threat to pig farming, and the zoonotic potential of peste des petits ruminants virus. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Please take the TWiV listener survey ASV 2019 European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed ASV in Poland does not let go (Ag Buiten ) Alarming ASF outbreak (Science) African swine fever (Euro Comm) African swine fever review (Vet J) ASF in wild boar (EFSA J) ASF in Belgian wild boar (Dept Env Food Rural Aff) Handbook on ASF in wild boar (Stand Grp Experts) Feral hogs (VA DGIF) Nonhuman morbillivirus with zoonotic potential (J Virol) Letters read on TWiV 532 Timestamps by Jolene. Thanks! Weekly Science Picks Alan - Retraction Watch database Rich- "The Mayo Clinic: Faith Hope Science" by Ken Burns Kathy- U-M EEB Photographer at Large contest Vincent - Vaccines: An achievement of civilization Listener Pick David- Useless Knowledge Begets New Horizons Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Patrick Moore returns to TWiV to discuss the discovery from the Chang-Moore laboratory of circular RNAs in cells infected with herpesviruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Patrick Moore Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Please take the TWiV listener survey ASV 2019 European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed Cancer virology at Pitt Alice Huang's DI particles (PubMed) Circular DNA tumor viruses make circular RNAs (PNAS) Backsplice Image credit Timestamps by Jolene. Thanks! Weekly Science Picks Brianne – The herd to the rescue Alan – Magic Wings Butterfly Conservatory Dickson – 100,000 Genomes Project Kathy – Your Age on Other Worlds Vincent – Vitamin D and Prevention of Cancer and Cardiovascular Disease Pat – North Korea and Bioweapons Listener Pick Eric – The Molecular Basis of Life Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Steve Goff returns to TWiV to discuss the work of his laboratory on how retroviral genomes are silenced in infected cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Steve Goff Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! 🎼 They'll histone you when you start to transcribe, And they'll histone you just for tryin' to get by, So be careful when you uncoat your genome, 'Cause everybody must histone. Links for this episode Please take the TWiV listener survey ASV 2019 European Congress of Virology 2019 Histones loaded onto incoming retroviral DNA (Cell Host Micr) NP220 and silencing of incoming retroviral DNA (Nature) HIV-1 and HUSH (TWiV 516) TWiV World Tour 2018 t-shirt Timestamps by Jolene. Thanks! Weekly Science Picks Alan - The Tangled Tree by David Quammen Dickson- Ammonia could power the globe Kathy- Portmanteaux and A.Word.A.Day Vincent - Curioscity Steve- Alice and Bob Meet the Wall of Fire Listener Pick Chaim- Tony Fauci on getting your flu vaccine (mp3) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv