This Week in Virology

The TWiVologists consider whether to receive an influenza vaccine in August (in the northern hemisphere), and mice implanted with human lung fragments for studying microbial pathogens. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Waning of influenza vaccine protection (Clin Inf Dis) Precision mouse models for microbial pathogenesis (Nat Biotech) Letters read on TWiV 563 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - Why we need to increase diversity in the immunology research community Alan - Stock photos of vaccination that don't suck Kathy- Sample size calculator Vincent- How Economics Shapes Science by Paula Stephan Listener Picks Melinda - Zome Tools Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

TWiV travels to Rutgers University to speak with Brad, Kay, Siobain, and Kim about their careers and their work on viruses of plants, fungi, bacteria, diatoms, and coccolithophores. Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker Guests: Brad Hillman, Kay Bidle, Siobain Duffy, and Kim Thamatrakoln Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Viruses of plant-interacting fungi (Adv Virus Res) Why are RNA virus mutation rates so damn high? (PLoS Biol) CRESS viruses (Adv Virus Res) Coccolithovirus facilitation of carbon export in North Atlantic (Nat Micro) Silicon limitation facilitates virus infection of marine diatoms (Nat Micro) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The Autonomous CollecTWiVe reveal two effective treatments for Ebolavirus infection, how a virus in a fungus confers heat tolerance to a plant, and dampened inflammation as a mechanism for bat tolerance to viral infection. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Two new and effective Ebolavirus treatments (NIH, Nature) A virus in a fungus in a plant (Science) Dampened NLRP3-mediated inflammation in bats (Nat Micro) Bat tolerance to virus infection (Nat Micro) Image credit Letters read on TWiV 561 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - Deaf student makes sign language terms to communicate science Alan - Show Your Stripes Vincent- Sixty Years of Discovery Listener Picks Eric - This drug could end HIV - why hasn't it? Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

From the meeting of the Centers of Excellence for Influenza Research and Surveillance, Vincent speaks with Alan, Florian and Jennifer about their careers, the purpose of CEIRS, universal influenza vaccines, and cellular responses to infection in pediatric populations. Host: Vincent Racaniello Guests: Alan Embry, Florian Krammer, and Jennifer Nayak Become a patron of TWiV! Links for this episode NIAID CEIRS 12th CEIRS meeting summary (pdf) Antibody response to influenza virus (Nat Rev Micro) Influenza virus CD4 T cells in children and young adults (Sci Rep) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The complete TWiV team give a report on the Ebola virus outbreak in DRC, and reveal that cell surface nectin proteins cause the transfer of cytoplasmic cargo, including measles virus, between cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Fire Alarm at ASV Ebola outbreak sitrep(WHO) Ebola outbreak dashboard(WHO) Ebola outbreakDRC (MSF) Ebola articles at CIDRAP Ebola virus vaccine could run out(STAT news) Nectin mediated cytoplasmic transfer(J Cell Sci) Letters readon TWiV 559 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - DukeMed Distinguished Award: Bill Joklik Alan - Audubon photography awards for 2019 Rich - Joklik paper on vaccinia virus mRNA; Joklik MEM Dickson- Ghost orchid pollination revealed Kathy- Crocheted petri plates Vincent- Documents relating to history of ASV Listener Picks Neva - What happens if we engineer a superbug? Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

From ASV 2019 at the University of Minnesota, TWiV explores the origins of the American Society for Virology with Sid Grossberg and Pat Spear. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guests: Sid Grossberg and Pat Spear Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode American Society for Virology Bill Joklik, 92 How ASV was founded (Virology) Signatures at the Chicago meeting (page one, page two) Timeline history of ASV (jpg) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

From the European Congress of Virology in Rotterdam, Vincent and local co-host Ben Berkhout speak with Ron Fouchier, Rosina Girones, and Marie-Paule Kieny about their careers and their work on influenza virus, environmental virology, and developing an Ebola virus vaccine during an epidemic. Hosts: Vincent Racanielloand Ben Berkhout Guests: Ron Fouchier, Rosina Girones, and Marie-Paule Kieny Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ECV2019 Drift of human H2N2 viruses (J Viral) Viruses in urban sewage (Sci Tot Environ) Ebola virus vaccine efficacy (Lancet) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

TWiV minus one reveals delayed neurological deficits in children without microcephaly born to Zika virus infected mothers, and N-glycolyl-neuraminic acid as a receptor for influenza A viruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Deficits in children born to Zika virus infected mothers (Nat Med) Zika virus is still a threat (NY Times) N-glycolyl-neuraminic acid as influenza virus receptor (Cell Rep) Letters read on TWiV 556 Timestamps by Jolene. Thanks! Weekly Science Picks Brianne - Foldable viral capsid models and Foldable models demonstrate T numbers Alan - Laws Guide to Nature Drawing and Journaling Dickson- NASA 50th Events Kathy- Alta Obscura's 17,069 strange and wonderful places Vincent- TWiEVO 44: The enemy of my enemy is my phage Listener Picks Anthony - Global Water Pathogen Project Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

From ASM Microbe 2019, Vincent, Brianne and Calvin meet up with Craig Cameron to discuss his career and his work exploring RNA-dependent RNA synthesis and single cell virology. Hosts: Vincent Racaniello, Brianne Barker, and Calvin Yeager Guest: Craig Cameron Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Cameron laboratory Curioscity podcast Ribavirin is an RNA virus mutagen (Nat Med) RNA virus error catastrophe: test using ribavirin (PNAS) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

A trio TWiVers reports on influenza in Australia, how a host protein impacts bird to human movement of influenza virus, and marine DNA viral diversity in the oceans from pole to pole. Hosts: Vincent Racaniello, Kathy Spindler, and Alan Dove Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Australian Influenza Surveillance Real-time tracking of influenza H3N2 ANP32B, or not to be (eLife) ANP32B on TWiV 377 Species specific differences in ANP32B for influenza virus replication (eLife) Marine viral DNA diversity pole to pole (Cell) Letters read on TWiV 554 Timestamps by Jolene. Thanks! Weekly Science Picks Alan - Stephanie Langel's Discovery Talk Kathy- Map of languages in the USA Vincent- Grad student mental health with Susanna Harris video and on TWiM 199 Listener Picks Fernando - Pushing back on hyped-up science Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv