MDS Podcast

Dr. Michele Matarazzo interviews Dr. Olivier Rascol on the results of the clinical trial recently published in the New England Journal of Medicine. Tune in to learn about the mechanisms of action and potential of lixisenatide and other GLP-1 receptor agonists in impacting the progression of Parkinson's disease. Read the article »

Dr. Müller-Vahl joins the podcast to discuss her retrospective study examining the key features in differentiating Tourette syndrome and Functional tic-like behaviors and that comorbidity is far more common than originally thought. Read the article »

In this Hot Topic episode, Dr. Sarah Lidstone moderates a discussion with Dr. Mark Hallett and Prof. Mark Edwards on the limitations of phenomenology in movement disorders. Drawn from a recent viewpoint by Prof. Edwards and using functional movement disorder as an example, they discuss the benefits and drawbacks of a phenotype equaling disease paradigm, the voluntary vs. involuntary movement disorder, and what we can learn from functional movement disorders.

Dr. Michele Matarazzo interviews Dr. Jacy Parmera about her recently published article on the clinical and neuroimaging characteristics of patients with corticobasal syndrome, with a focus on the potential correlation with the underlying neuropathological causes. Read the article »

Profs. Elena Moro and Ruth Walker discuss the management of chorea, including when this is appropriate. They focus on Huntington’s disease and the role of deep brain stimulation and other surgical interventions, in addition to medical management.

Dr. Sara Schaefer speaks with Doctors Xiaojun Huang and Jingying Wu about the phenotypic and genotypic spectrum of CSF1R-related disorder in a Chinese population, including unique clinical and radiographic characteristics. Journal CME is available until May 21, 2025 Read the article.

Dr. Ruth Walker and Dr. Molly Cincotta discuss causes of acquired chorea and approach to the work-up of a patient with an acquired chorea.

In this Hot Topic episode, Dr. Michele Matarazzo interviews Dr. Raul Martinez on the recent evidence and future applications of focused ultrasound-based ablations in movement disorders, such as Parkinson's disease and essential tremors. Discover how this innovative approach is improving patient care and what it could mean for the future of medical treatment.

In the latest installment of the Chorea Special Series, Dr. Ruth Walker interviews Prof. Sarah Tabrizi about the current state of therapies for Huntington’s disease, and what is coming down the pipeline.

Dr. Sarah Camargos interviews Dr. Zhonghbo Chen and Prof. Henry Houlden, first and senior author of a MDJ paper exploring a GGC repeat expansion in the ZFHX3 gene associated with spinocerebellar ataxia type 4. They describe a criative methodology to find a gene in a family with a Swedish ancestry. Journal CME is available until April 04, 2025 Read the article.