MDS Podcast

Dr. Sara Schaefer discusses with Prof. Marc Vérin and Prof. Mahmoud Hassan their recent paper in Movement Disorders Journal on the use of Resting-State High-Density EEG to neurophysiologically stratify Parkinson's patients into subtypes in an effort to predict cognitive and motor progression, properly evaluate for invasive therapies, and inform future clinical research. Read the article

For this Hot Topics episode, Dr. Eduardo Fernandez sits down with Dr. Thomas Beach to discuss the advances and challenges ahead in tissue biomarkers for Parkinson's disease, including colon, salivary gland and skin biopsies.

Dr. Esther Cubo joins Dr. Sarah Lidstone and the MDS Podcast to discuss her recent work on the Spanish validation of the MDS Non-Motor Rating Scale. Together to go over the reasoning for this study, the extensive process of validating this scale and what benefits it will provide to Spanish speaking populations. Read the article MDS Non-motor Rating Scale

The Global Parkinson's Genetics Program (GP2) is a project designed to understand the architecture of Parkinson's disease (PD). Dr. Sarah Camargos sits down with Dr. Andrew Singleton to discuss GP2 and its initiative to increase our global understanding of PD and in doing so, better understand the genetic landscape of underrepresented populations.

Laryngeal dystonia (LD) is a rare disorder affecting the vocal cords. Dr. Sarah Camargos sits down with Prof. Kristina Simonyan while she breaks down the methodology and findings of her comprehensive study investigating the temporal-spatial signature of LD. Read the article

Dr. Sara Schaefer speaks with Dr. Beatrice Heim, author of the MDCP Review Article of the Year 2023, about alpha-synuclein seed amplification assays of the CSF and their use in the diagnosis of synucleinopathies. Read the article

Dr. Poewe and Dr. Mahlknecht discuss the details of their Review Article of the Year on what we know about how DBS in Parkinson's disease alters symptoms, disability, survival, and more in this special episode. Read the article

Dr. Eduardo Fernandez interviews Professor Günther Deuschl and Dr. Robin Wolke on their recent MDCP article on the challenges levodopa poses when predicting the outcome of subthalamic deep brain stimulation. Read the article

What gene therapies are the most promising the field of movement disorders? Dr. Sarah Camargos met with Prof. Deniz Kirk at the 2023 MDS Congress to get his perspective on how the field of gene therapy has evolved over the years and where it has yet to go.

The role of alpha-synuclein in various proteinopathies is still unknown. Prof. Poul Henning Jensen discusses this hot topic with Prof. Tiago Outeiro.