The Incubator

Send us a textPlacental Pathology Contributes to Impaired Volumetric Brain Development in Neonates With Congenital Heart Disease.Nijman M, van der Meeren LE, Nikkels PGJ, Stegeman R, Breur JMPJ, Jansen NJG, Ter Heide H, Steenhuis TJ, de Heus R, Bekker MN, Claessens NHP, Benders MJNL; CHD LifeSpan Study Group ‡.J Am Heart Assoc. 2024 Mar 5;13(5):e033189. doi: 10.1161/JAHA.123.033189. Epub 2024 Feb 29.PMID: 38420785 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textResponse categorization and outcomes in extremely premature infants born at 22-26 weeks gestation that received inhaled nitric oxide for hypoxic respiratory failure.Boly TJ, Dagle JM, Klein JM, Rios DR, McNamara PJ, Giesinger RE.J Perinatol. 2023 Mar;43(3):324-331. doi: 10.1038/s41372-022-01582-4. Epub 2022 Dec 12.PMID: 36509816 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textPatent Ductus Arteriosus and Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Bayesian Meta-Analysis.Villamor E, van Westering-Kroon E, Gonzalez-Luis GE, Bartoš F, Abman SH, Huizing MJ.JAMA Netw Open. 2023 Nov 1;6(11):e2345299. doi: 10.1001/jamanetworkopen.2023.45299.PMID: 38015504 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textVasopressin in newborns with refractory acute pulmonary hypertension.Ouellet S, Drolet C, Morissette G, Pellerin A, Hébert A.Pediatr Res. 2024 May;95(6):1572-1577. doi: 10.1038/s41390-023-02995-3. Epub 2024 Jan 11.PMID: 38212386Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textImpact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in "22-23" week and "24-26" infants.Giesinger RE, Hobson AA, Bischoff AR, Klein JM, McNamara PJ.Semin Perinatol. 2023 Mar;47(2):151721. doi: 10.1016/j.semperi.2023.151721. Epub 2023 Mar 5.PMID: 36882362Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textPerioperative Brain Injury in Relation to Early Neurodevelopment Among Children with Severe Congenital Heart Disease: Results from a European Collaboration.Neukomm A, Claessens NHP, Bonthrone AF, Stegeman R, Feldmann M, Nijman M, Jansen NJG, Nijman J, Groenendaal F, de Vries LS, Benders MJNL, Breur JMPJ, Haas F, Bekker MN, Logeswaran T, Reich B, Kottke R, Dave H, Simpson J, Pushparajah K, Kelly CJ, Arulkumaran S, Rutherford MA, Counsell SJ, Chew A, Knirsch W, Sprong MCA, van Schooneveld MM, Hagmann C, Latal B; European Association Brain in Congenital Heart Disease (EU-ABC) consortium.J Pediatr. 2024 Mar;266:113838. doi: 10.1016/j.jpeds.2023.113838. Epub 2023 Nov 22.PMID: 37995930 Free article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of the Incubator: At the Bench, we talk with Dr. Erin Plosa who is a neonatologist and physician scientist at Vanderbilt University Medical Center. We learn what inspired Dr. Plosa to pursue neonatology and learn about her background and career as a lung biologist. Dr. Plosa talks about the importance of collaboration in scientific research and highlights her work studying the role of integrins and the extracellular matrix during lung development. She discusses the role of the extracellular matrix in alveologenesis, fusion of the alveolar capillary barrier, and in directing communication between epithelial and endothelial cells. We also discuss Erin's experience with mentorship and career development, including her transition into becoming a mentor and winning mentoring awards. Erin shares her approach to mentoring and the importance of fostering intellectual curiosity. Join us as we learn more about what it takes to build a career as a neonatology physician-scientist and how the extracellular matrix directs lung development and response to injury. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this engaging episode of The Incubator podcast, Dr. Terrie Inder, a pioneer in neonatal neurology, shares her journey and insights into newborn brain development. Dr. Inder discusses the complexities of neonatal brain injury, emphasizing that it's not just about visible hemorrhages, but also about the brain's overall maturation process. She highlights the importance of understanding "brain dysmanturation" and how the NICU environment significantly impacts neurodevelopment.Dr. Inder challenges the neonatal community to rethink their approach to brain care, advocating for more family involvement, enriched environments, and tailored interventions for babies with brain injuries. She stresses the need for better hemodynamic management and a sociocultural shift in NICU care delivery.The conversation also touches on the controversial topic of routine MRI scans, with Dr. Inder arguing for their value in risk profiling and guiding care. She encourages neonatologists to embrace learning about brain imaging and improve their communication skills with families.Throughout the episode, Dr. Inder's passion for improving outcomes for NICU babies shines through, offering listeners valuable insights and a call to action for enhancing neonatal brain care. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode, Dr. Stephen Swanson shares his journey of establishing a neonatal intensive care unit (NICU) in Arusha, Tanzania. He emphasizes the importance of addressing medical culture and involving nurses, doctors, and families in the care of critically ill and premature babies. Dr. Swanson highlights the success of a low-tech approach, including the use of blended, warmed, and humidified CPAP, and the importance of attention to detail, thermal regulation, respiratory support, nutrition, and infection prevention. He also discusses the challenges of relying on donated equipment and the need for innovative biomedical engineering solutions.  Dr. Swanson also highlights the need for appropriate training and skill development for healthcare providers, as well as the importance of collaboration and sharing of best practices. He shares his experience in organizing the Tiny Feet Big Steps African Neonatology Conference, which aims to provide practical skills and knowledge to healthcare professionals in Africa. Dr. Swanson also discusses his vision for the Institute for Child Healthcare Africa, which aims to promote quality pediatric care and build a mother and child hospital in Tanzania. Resources mentioned in episode: Tiny Feet Big Steps conference: https://tinyfeetbigsteps.com/Institute for Child Healthcare (ICHA): https://www.tanzanianchildren.com/Every Breath Counts: Lessons Learned in developing a training NICU in Northern Tanzania: https://www.frontiersin.org/articles/10.3389/fped.2022.958628/full Contact: swan0027@umn.edu Episode Webpage Link: https://www.the-incubator.org/post/225-low-tech-high-impact-caring-for-neonates-in-arusha-tanzania-ft-dr-stephen-swanson Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this packed episode of Journal Club, Ben and Daphna review eleven recent papers covering a range of neonatology topics. They discuss a study on CRP use in early-onset sepsis evaluations, finding that high CRP use was associated with increased antibiotic administration. Another paper examined iron supplementation in healthy breastfed infants, showing no significant developmental benefits at 12-36 months.They review a JAMA Network Open study on the long term outcomes of infants enrolled in the umbilical cord milking study MINVI. They also cover a paper on cannabis use in pregnancy, noting a significantly increased risk of fetal death associated with maternal cannabis use.Other topics include antibiotic exposure and BPD risk in very preterm infants, comparisons of different BPD definitions, and the effects of phototherapy on plasma metabolites in preterm infants with hyperbilirubinemia.The episode features a special segment with Dr. James Sotiropoulos discussing his recent paper on initial oxygen concentrations for resuscitating extremely preterm infants. The study found a potential mortality benefit with higher initial FiO2, though more research is needed.Ben and Daphna also review papers on improving NICU communication and antenatal consultation practices. They close by welcoming new trainees starting in July and reminding listeners about The Incubator's board review resources for neonatology fellows.Overall, this comprehensive episode provides an excellent overview of recent impactful research across multiple areas of neonatology and perinatal medicine. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!