The Incubator

Send us a textIn this episode of Journal Club, Ben and Daphna discuss several recent neonatal studies. They begin with a paper from Pediatrics examining variability in care practices for extremely early deliveries (22-24 weeks gestation), highlighting changes over time and persistent differences between centers. They also review a commentary on important questions raised by these variations in care.The hosts then analyze a study on the use of inhaled nitric oxide in preterm infants, discussing its effectiveness, costs, and potential overuse. They cover a paper on monocyte count trends as a potential diagnostic tool for necrotizing enterocolitis.A special segment features Dr. Jane Stremming discussing a New England Journal of Medicine study on nutritional support for moderate to late preterm infants. The hosts also touch on new treatments for hemolytic disease of the fetus and newborn, and surfactant use in infants who develop bronchopulmonary dysplasia.The episode concludes with an ethical case study about a father's unexpected request to withdraw care for his preterm infant, emphasizing the importance of understanding families' perspectives in complex medical decisions. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textEffects of a live versus heat-inactivated probiotic Bifidobacterium spp in preterm infants: a randomised clinical trial.Athalye-Jape G, Esvaran M, Patole S, Nathan EA, Doherty DA, Sim E, Chandrasekaran L, Kok C, Schuster S, Conway P.Arch Dis Child Fetal Neonatal Ed. 2024 Aug 17:fetalneonatal-2023-326667. doi: 10.1136/archdischild-2023-326667. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textVariability of Care Practices for Extremely Early Deliveries.LoRe D, Groden CM, Schuh AR, Holmes C, Ostilla L, Vogel MM, Murray PD, Yamasato K, Tonismae T, Anani UE, Henner N, Famuyide M, Leuthner SR, Laventhal N, Andrews BL, Tucker Edmonds BM, Brennan KG, Feltman DM; INVESTIGATING NEONATAL DECISIONS FOR EXTREMELY EARLY DELIVERIES (INDEED) STUDY GROUP.Pediatrics. 2024 Aug 12:e2023065521. doi: 10.1542/peds.2023-065521. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textThe Value of Parental Judgment in the Ethical Gray Zone of Periviability: Words Matter.Drago MJ, Mercurio MR.Pediatrics. 2024 Aug 7:e2024065986. doi: 10.1542/peds.2024-065986. Online ahead of print.PMID: 39108223 No abstract available.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textFour Important Questions About Between-Hospital Differences in Care at <25 Weeks' Gestation.Rysavy MA, Battarbee AN, Gibson KS.Pediatrics. 2024 Aug 12:e2024066182. doi: 10.1542/peds.2024-066182. Online ahead of print.PMID: 39129508 No abstract available.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textRetrospective study of preterm infants exposed to inhaled nitric oxide in Kaiser Permanente Southern California: morbidity, mortality and follow-up.Bhatt DR, Braun D, Dizon RA, Shi JM, Weerasinghe S, Sabio A, Reddy S, Lee HC, Ramanathan R, Lakshminrusimha S.J Perinatol. 2024 Jul 18. doi: 10.1038/s41372-024-02051-w. Online ahead of print.PMID: 39025953As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textSurfactant treatment at birth in a contemporary cohort of preterm infants with bronchopulmonary dysplasia.Mueller C, Shepherd EG, Kielt MJ, Conroy S, Jensen EA, Bamat NA, Panitch H, Levin J, Guaman Cuevas M, Truog W, Abman SH, Nelin LD; BPD Collaborative.J Perinatol. 2024 Jul 17. doi: 10.1038/s41372-024-02061-8. Online ahead of print.PMID: 39020028As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textBeyond the Question: Reexamining a Parent's Unusual Request.Callahan KP, Narva A, Stoller JZ, Fiester A.Pediatrics. 2024 Aug 1;154(2):e2023064954. doi: 10.1542/peds.2023-064954.PMID: 39040023 As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textDr. Steve McElroy, a neonatologist and physician scientist, discusses his research on injury and repair mechanisms in the immature intestine, specifically focusing on necrotizing enterocolitis (NEC) and spontaneous intestinal perforation in premature infants. He shares his journey from initially not wanting to pursue science to becoming a physician scientist, and how mentorship played a crucial role in his career. Dr. McElroy also talks about his pioneering work on Paneth cells and the Paneth cell ablation NEC model. He highlights the importance of listening, asking questions, and being open to new research directions. Finally, he discusses the impact of his leadership role as a division chief on his research and mentorship activities. He emphasizes the importance of mentorship, celebrating small victories, and persisting through challenges. Dr. McElroy also shares insights into his current research on chorioamnionitis and its impact on neonatal health. He highlights the need for creative think time and the value of understanding mechanisms in basic science. The conversation concludes with a discussion on building a supportive and fun lab environment. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textGear up for a groundbreaking event in neonatal care! The Delphi Neonatal Innovation Conference is set to take Fort Lauderdale by storm from September 23-25. Hosted by Ben Courchia and Daphna Yasova Barbeau from the Incubator podcast, this conference promises a unique blend of cutting-edge content and networking opportunities.Highlights include three free workshops: Point-of-Care Ultrasound with state-of-the-art equipment, Artificial Intelligence in Neonatology, and Narrative Medicine. The event features exciting pitch presentations showcasing innovative neonatal technologies, from synchronized high-flow nasal cannula to wearable phototherapy devices.Don't miss the fellowship trivia competition, offering a chance to win an educational grant. The conference also includes a special TEDx event with prestigious speakers discussing topics ranging from environmental impacts on perinatal outcomes to creativity within limitations.An evening of powerful storytelling by NICU professionals promises to be a moving experience. For those unable to attend in person, high-quality live streaming is available.With its focus on practical innovation and networking, the Delphi Neonatal Innovation Conference is set to be an unmissable event for anyone passionate about advancing neonatal care. Register now to be part of this transformative experience! As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!