The Incubator

Send us a textIn this episode of The Incubator podcast, hosts Ben Courchia and Daphna Barbeau welcome Dr. David Askenazi and Dr. Tara Beck to discuss neonatal nephrology. The conversation explores the challenges of defining and diagnosing acute kidney injury (AKI) in newborns, highlighting the variability in nephron numbers at birth and the complexities of interpreting creatinine levels in the first days of life.The guests discuss the long-term effects of neonatal AKI, the importance of follow-up care, and strategies for supporting kidney health in the NICU and beyond. They emphasize the need for a partnership between neonatology and nephrology to improve outcomes.Dr. Askenazi introduces the Neonatal Kidney Collaborative (NKC), explaining its mission to advance research, education, and advocacy in neonatal nephrology. Dr. Beck shares her experience as a trainee involved with the NKC, highlighting the mentorship opportunities available.The episode concludes with a look towards the future of neonatal nephrology research, including potential therapies and the evolving approach to renal replacement therapy in newborns. This informative discussion provides valuable insights for both neonatologists and nephrologists caring for vulnerable newborns. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of Journal Club, hosts Ben and Daphna dive into several impactful studies in neonatology. They begin with a series of papers on patent ductus arteriosus (PDA) management, discussing pharmacological treatments, transcatheter closure techniques, and new clinical practice guidelines. The conversation highlights the evolving landscape of PDA treatment and the need for more robust research.The hosts also explore a study on diazoxide for neonatal hypoglycemia, examining its effects on glycemic stability and feeding outcomes. They discuss recent findings on infant mortality rates in Texas following abortion restrictions, emphasizing the impact of policy changes on neonatal health outcomes.Additionally, the episode covers a systematic review of quality improvement interventions to prevent intraventricular hemorrhage in preterm infants, highlighting the complexity of implementing effective "neurobundles".The hosts conclude with a study on vasopressin as an adjunctive therapy for pulmonary hypertension in term newborns, noting its potential benefits in improving oxygenation and hemodynamic status.Throughout the episode, Ben and Daphna provide insightful commentary on the clinical implications of these studies, making complex research accessible to listeners while emphasizing the need for continued investigation in key areas of neonatal care. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textAcetaminophen for Patent Ductus Arteriosus and Risk of Mortality and Pulmonary Morbidity.Jensen EA, DeMauro SB, Rysavy MA, Patel RM, Laughon MM, Eichenwald EC, Do BT, Das A, Wright CJ; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.Pediatrics. 2024 Jul 16:e2023065056. doi: 10.1542/peds.2023-065056. Online ahead of print.PMID: 39011550As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textTranscatheter and Surgical Ductus Arteriosus Closure in Very Low Birth Weight Infants: 2018-2022.Leahy BF, Edwards EM, Ehret DEY, Soll RF, Yeager SB, Flyer JN.Pediatrics. 2024 Jul 15:e2024065905. doi: 10.1542/peds.2024-065905. Online ahead of print.PMID: 39005106As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textLong term follow-up of patients with patent ductus arteriosus after transcatheter closure.Peng Y, Cheng Z, Zhang Y, Yi Q.Pediatr Res. 2024 Jun 14. doi: 10.1038/s41390-024-03317-x. Online ahead of print.PMID: 38877281As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textInfant Deaths After Texas' 2021 Ban on Abortion in Early Pregnancy.Gemmill A, Margerison CE, Stuart EA, Bell SO.JAMA Pediatr. 2024 Jun 24:e240885. doi: 10.1001/jamapediatrics.2024.0885. Online ahead of print.PMID: 38913344As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textQuality Improvement Interventions to Prevent Intraventricular Hemorrhage: A Systematic Review.Edwards EM, Ehret DEY, Cohen H, Zayack D, Soll RF, Horbar JD.Pediatrics. 2024 Jul 10:e2023064431. doi: 10.1542/peds.2023-064431. Online ahead of print.PMID: 38982935 As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textWhere Are All the Pediatricians?Jordan KA, Rao P, Byerley JS.JAMA. 2024 Jul 3. doi: 10.1001/jama.2024.8485. Online ahead of print.PMID: 38958947As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textProcedural closure of the patent ductus arteriosus in preterm infants: a clinical practice guideline.Mitra S, Bischoff AR, Sathanandam S, Lakshminrusimha S, McNamara PJ.J Perinatol. 2024 Jul 12. doi: 10.1038/s41372-024-02052-9. Online ahead of print.PMID: 38997403 Review.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textVasopressin as adjunctive therapy in pulmonary hypertension associated with refractory systemic hypotension in term newborns.Santelices F, Masoli D, Kattan J, Toso A, Luco M.J Perinatol. 2024 Jul 4. doi: 10.1038/s41372-024-02015-0. Online ahead of print.PMID: 38965377As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!