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American Journal of Psychiatry Audio

Latest episodes

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Jul 1, 2025 • 25min

July 2025: National Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States

Dr. Tanner Bommersbach (University of Wisconsin School of Medicine and Public Health) and Dr. Greg Rhee (University of Connecticut and Yale University School of Medicine) join AJP Audio to discuss estimating national trends in suicidal ideation and attempts in high school students with and without accompanying high-risk behaviors.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the July issue of the Journal. 00:07   Bommersbach and Rhee interview 00:36   Trends in suicide among high school students in the US 02:49   Variation in rates based on gender, racial identity, and sexuality 03:50   Did the rates increase during the COVID-19 pandemic? 04:14   Lessons to be learned from COVID? 05:23   Behavior risk factors 06:33   Clinical implications 08:19   Inflections in risk factors due to the pandemic? 08:52   Limitations 09:32   Future research 10:16   Kalin interview 10:31   Bommersbach et al. 14:20   Müller et al. 18:54   Ahn et al. 21:47   McCabe et al. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Jun 1, 2025 • 33min

June 2025: Stratifying Risk for Postpartum Depression at Time of Hospital Discharge

Dr. Roy Perlis (Mass General Bringham, Boston) joins AJP Audio to discuss a machine learning model to examine electronic health records in individuals who had recently given birth designed to detect those who might develop postpartum depression.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the June issue into context. 00:31     Perlis interview 02:56     Lack of validation in screening methods 04:03     Stumbling blocks on the road to validation 05:10     Synergy between screening scores and machine learning models 06:36     Issues with clinician adoption? 08:44     Administrative burden for running these models 10:38     Current clinical application 12:37     Screening without those with a history of depression 13:48     Limitations 15:30     Future research 17:26     Kalin interview 17:41     Clapp et al. 21:41     Kępińska et al. 25:19     Savitz et al. 25:25     Miller 28:38     Wall et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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May 1, 2025 • 36min

May 2025: Randomized Controlled Trial of “Bounce Back Now,” a Mobile App to Reduce Post-Disaster Symptoms of Posttraumatic Stress, Depressed Mood, and Sleep Disturbance

Dr. Kenneth Ruggiero (Medical University of South Carolina, Charleston) joins AJP Audio to discuss the the effectiveness of an app-based intervention at reducing the symptoms of sleeplessness and posttraumatic stress in a broad cohort in the wake of a natural disaster.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the May issue into context. 00:38     Ruggiero interview 03:13     Bounce Back Now app 05:03     Natural disasters and other sources of trauma 07:31     Low cost and broad-based intervention 08:49     Limitations 10:19     Changes in how the intervention was designed 11:17     Uptake and interactions with the app 13:15     Future directions 14:36     Kalin interview 14:50     Ruggiero et al. 19:26     Norman et al. 23:29     Conrod et al. 27:53     Olfson et al. 31:44     Olfson et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Apr 1, 2025 • 23min

April 2025: Anticholinergic Burden and Cognitive Function in Psychosis: A Systematic Review and Meta-Analysis

Dr. Valentina Mancini (Oxford University) joins AJP Audio to discuss the impact of anticholinergic burden on cognition in patients with schizophrenia.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context. 00:32     Mancini interview 02:26     Anticholinergic burden method of action 02:58     Balancing the impact of side effects in schizophrenia treatment 04:52     Limitations 05:34     The need for further studies 05:59     Clinical implications 06:32     Further research 07:01     Trials needed 07:54     Kalin interview 08:03     Mancini et al. 11:23     Tiihonen et al. 13:43     Zhou et al. 16:28     Omlor et al. 18:51     Orhan et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Mar 1, 2025 • 32min

March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials

Dr. William Horan (Bristol Myers Squibb) joins AJP Audio to discuss a newly approved, novel treatment for schizophrenia spectrum disorder, which has potential impacts for cognition in patients.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context. 00:45     Horan interview 03:15     Novel mechanism of action in the treatment of schizophrenia 05:39     Side effect profiles 07:20     Clinical impacts 08:31     The need for further investigation 09:58     Limitations 11:05     Further research 13:08     Kalin interview 13:21     Horan et al. 17:34     Levenstein et al. 19:00     Fountoulakis et al. 20:57     Couture et al. 23:18     Stern et al. 27:35     McGirr et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Feb 1, 2025 • 45min

February 2025: Real-Time Assessment of Alcohol Reward, Stimulation, and Negative Affect in Individuals With and Without Alcohol Use Disorder and Depressive Disorders

Dr. Andrea King (University of Chicago Medicine) joins AJP Audio to discuss a novel, real time assessment of the reward, stimulation, and negative affect of alcohol use in people with alcohol use disorder with and without depressive disorders.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the February issue, which focuses closely on issues surrounding addiction. 00:35     King interview 00:45     Allostatic model of addiction 02:12     Gathering data and the groups studied 07:37     The ethics of studying alcohol use in patients with AUD 10:38     Findings 13:29     The impacts of alcohol’s pleasurable effects on people with AUD and those without 14:32     Limitations of natural environment research versus laboratory research 18:18     Clinical implications 20:09     Further research 22:56     Kalin interview 23:03     King et al. 26:21     Brand et al. 28:12     Conway et al. 32:17     Kypriotakis et al. 35:42     Kuhn et al. 39:37     Grilo et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Jan 1, 2025 • 19min

January 2025: Special Issue on Psychedelics

Dr. Charles Nemeroff (University of Texas at Austin) joins AJP Editor-in-Chief Dr. Ned Kalin to discuss the January issue of the American Journal of Psychiatry. Dr. Nemeroff is a guest editor of the special issue, which takes a close look at the potential, pitfalls, and clinicial implications of psychedelics in mental health treatment. 00:38     Nemeroff interview 02:27     McIntyre et al. 04:06     Ramaekers et al. 05:44     Ghaznavi et al. 08:01     Fonzo et al. 09:17     Wolfgang et al. 10:45     Psychedelics and psychotherapies 12:31     Aaronson et al. 14:17     Pagni et al. 15:31     Kirlić et al. 17:06     Olson Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Dec 1, 2024 • 30min

December 2024: Discrimination Exposure, Neural Reactivity to Stress, and Psychological Distress

Devon Grey and David Knight (University of Alabama, Birmingham) join AJP Audio to discuss how exposure to discrimination impacts neural reactivity to stress and psychological distress in adolescents.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins us to discuss the rest of the December issue of AJP. 00:36     Grey and Knight interview 02:41     Demographics of the cohort 03:46     Neurobiological mechanisms of discrimination impacts 06:14     Racial discrimination and mental health impacts 09:34     Discrimination as a chronic stressor and prolonged activation of the stress response system 10:45     Limitations 13:52     Further research 14:38     Kalin interview 14:52     Grey et al. 17:35     Sippel et al. 18:06     Fox and Shackman 19:42     Kliemann et al. 22:16     Kamboj et al. 27:07     Pathak et al. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Nov 1, 2024 • 28min

November 2024: Disparities in Treatment for Alcohol Use Disorder Among All of Us Participants

Dr. Phuc Le (Cleveland Clinic, Case Western Reserve University, Cleveland) joins AJP Audio to discuss racial, ethnic, and sociodemographic disparities in treatment in alcohol use disorder among participants of the All of Us cohort.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins to discuss the rest of the November issue, which takes a close look at issues surrounding substance use disorders. 00:41     Le interview 01:52     Disparities in treatment of AUDs in the US 03:43     What is the VA system doing right? 05:25     All of Us 06:39     Immediate clinical implications 08:15     Limitations 09:38     Further research 10:55     Kalin interview 11:07     Le et al. 13:44     Imperio et al. 14:43     McClure et al. 17:23     Perlman et al. 20:57     Savage et al. 24:17     Compton et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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Oct 1, 2024 • 36min

October 2024: Real-World Effectiveness of Menopausal Hormone Therapy in Preventing Relapse in Women With Schizophrenia or Schizoaffective Disorder

Dr. Bodyl Brand (Oxford University, UK) joins AJP Audio to discuss the effectiveness of menopausal hormone therapy in preventing psychosis relapse in women with schizophrenia and schizoaffective disorder.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin takes us through the rest of the October issue of the American Journal of Psychiatry, which focuses on other issues touching psychosis and schizophrenia spectrum disorders. 01:05     Brand interview 03:08     MHT and potential side effects in schizophrenia treatment 06:16     Estrogen and psychosis prophylaxis 07:44     MHT effectiveness 10:15     Clinical implications 11:27     Strengths and limitations 13:47     The need for further study 15:54     Further research 17:24     Kalin interview 17:47     Brand et al. 20:17     Partanen et al. 23:54     Moran et al. 26:48     Gallucci et al. 30:38     Arion et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

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