Dr. Shau-Ming Wei (National Institute of Mental Health, Bethesda, MD) joins AJP Audio to discuss a replication study looking at impact of hormone addback to a hormone suppression regimen for the treatment of premenstrual dysphoric disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the October issue of the Journal.

00:34 Wei interview
02:59 PMDD
04:22 Up and downsides of hormone suppression
05:52 Hormone addback
07:15 Limitations of the current study
08:38 Further research
10:42 Kalin interview
10:58 Wei et al.
15:25 Sanacora et al.
20:07 Whittle et al.
23:06 Cooper et al.

Transcript

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October 2025: Differential Effects of Ovarian Steroids in Women With and Without Premenstrual Dysphoric Disorder: A Replication and Extension of Findings