American Journal of Psychiatry Audio

Dr. Charles Nemeroff (University of Texas at Austin) joins AJP Editor-in-Chief Dr. Ned Kalin to discuss the January issue of the American Journal of Psychiatry. Dr. Nemeroff is a guest editor of the special issue, which takes a close look at the potential, pitfalls, and clinicial implications of psychedelics in mental health treatment. 00:38 Nemeroff interview 02:27 McIntyre et al. 04:06 Ramaekers et al. 05:44 Ghaznavi et al. 08:01 Fonzo et al. 09:17 Wolfgang et al. 10:45 Psychedelics and psychotherapies 12:31 Aaronson et al. 14:17 Pagni et al. 15:31 Kirlić et al. 17:06 Olson Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

Devon Grey and David Knight (University of Alabama, Birmingham) join AJP Audio to discuss how exposure to discrimination impacts neural reactivity to stress and psychological distress in adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins us to discuss the rest of the December issue of AJP. 00:36 Grey and Knight interview 02:41 Demographics of the cohort 03:46 Neurobiological mechanisms of discrimination impacts 06:14 Racial discrimination and mental health impacts 09:34 Discrimination as a chronic stressor and prolonged activation of the stress response system 10:45 Limitations 13:52 Further research 14:38 Kalin interview 14:52 Grey et al. 17:35 Sippel et al. 18:06 Fox and Shackman 19:42 Kliemann et al. 22:16 Kamboj et al. 27:07 Pathak et al. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

Dr. Phuc Le (Cleveland Clinic, Case Western Reserve University, Cleveland) joins AJP Audio to discuss racial, ethnic, and sociodemographic disparities in treatment in alcohol use disorder among participants of the All of Us cohort. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins to discuss the rest of the November issue, which takes a close look at issues surrounding substance use disorders. 00:41 Le interview 01:52 Disparities in treatment of AUDs in the US 03:43 What is the VA system doing right? 05:25 All of Us 06:39 Immediate clinical implications 08:15 Limitations 09:38 Further research 10:55 Kalin interview 11:07 Le et al. 13:44 Imperio et al. 14:43 McClure et al. 17:23 Perlman et al. 20:57 Savage et al. 24:17 Compton et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

Dr. Bodyl Brand (Oxford University, UK) joins AJP Audio to discuss the effectiveness of menopausal hormone therapy in preventing psychosis relapse in women with schizophrenia and schizoaffective disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin takes us through the rest of the October issue of the American Journal of Psychiatry, which focuses on other issues touching psychosis and schizophrenia spectrum disorders. 01:05 Brand interview 03:08 MHT and potential side effects in schizophrenia treatment 06:16 Estrogen and psychosis prophylaxis 07:44 MHT effectiveness 10:15 Clinical implications 11:27 Strengths and limitations 13:47 The need for further study 15:54 Further research 17:24 Kalin interview 17:47 Brand et al. 20:17 Partanen et al. 23:54 Moran et al. 26:48 Gallucci et al. 30:38 Arion et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

Dr. Jessica Salvatore, a researcher from Rutgers Robert Wood Johnson Medical School, dives into the fascinating world of peer social genetic effects on mental health. She discusses how the genetic makeup of peers can significantly influence adolescent risks for substance use, anxiety, and major depression. This insight challenges traditional genetic perspectives and emphasizes the role of social environments. Additionally, the conversation touches on the need for further research to explore these dynamics, paving the way for targeted interventions.

Dr. Evan Krueger, a researcher at Tulane University School of Social Work, explores how changes in sexual identity influence mental health and substance use in sexual minority adults. He discusses findings from the Generations study, revealing significant behavioral health disparities compared to cisgender heterosexuals. Krueger highlights generational differences in identity stability and emphasizes the need for more research on evolving identities, especially for younger individuals navigating their sexual orientation.

Dr. Lina Jonsson from Sweden discusses polygenic profiles and occupational dysfunction in bipolar disorder. Topics include genetic liabilities, personalized interventions, and antidepressant treatment. Other chapters explore GABA levels in depression, mental health impacts on cardiovascular health, and stress response in young adults.

Sara Tramazzo, a specialist from Stony Brook University, discusses the long-term outcomes for patients with psychotic disorders, revealing lower recovery rates compared to other studies. She highlights challenges in tracking patients over 25 years and the importance of differentiating between recovery and remission. Dr. Ned Kalin joins later to explore innovative treatment approaches and the potential use of neuromelanin as a biomarker in first-episode schizophrenia. Together, they shed light on the complex landscape of long-term psychiatric care.

Dr. ReJoyce Green, a substance use specialist from the Medical University of South Carolina, discusses key predictors of substance use initiation in early adolescents, highlighting the protective role of religious participation and sociodemographic factors. Dr. Ned Kalin and Dr. Kathleen Brady delve into the latest developments in understanding and treating substance use disorders, emphasizing the need for personalized interventions and the importance of demographic influences in effective prevention strategies.

Neuroscientist Dr. Soonjo Hwang discusses intranasal oxytocin in youths with severe irritability. They explore oxytocin effects, delivery methods, imaging, and clinical implications. The podcast highlights preliminary investigations, limitations, and the need for further research.