

Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast
Tania Dempsey, MD with Jill Brook, MA
Each episode is a deep dive on Mast Cell Activation Syndrome (MCAS) with a top physician, researcher or other expert who specializes in treating patients with MCAS. Hosted by Johns-Hopkins-trained world renowned specialist Tania Dempsey, MD, we take a practical approach to helping doctors and patients better manage MCAS. We cover the symptoms, testing, diagnosis, treatment, challenges, practical strategies, common comorbidities (e.g., POTS, hypermobility spectrum disorders, ME/CFS, autoimmunity, GI dysmotility), latest research findings and clinical pearls.
These episodes are a monthly feature of The POTScast, presented by Standing Up to POTS, a non-profit dedicated to improving life for those with POTS and related chronic illness. Check out our full podcast — with other types of great episodes — at ThePOTScast.com.
These episodes are a monthly feature of The POTScast, presented by Standing Up to POTS, a non-profit dedicated to improving life for those with POTS and related chronic illness. Check out our full podcast — with other types of great episodes — at ThePOTScast.com.
Episodes
Mentioned books

Nov 8, 2023 • 55min
Dr. Lawrence Afrin on MCAS Diagnostic Criteria “Consensus-2”
Dr. Afrin, a world expert in all things mast cell, talks in depth about issues with the first MCAS "consensus" statement and the need for a second MCAS consensus statement so that patients can be treated even if their lab tests don't show an elevation of tryptase levels. This opens the diagnostic door to many additional patients so that they can get the treatment that they need.
You can read the transcript for this episode here: https://tinyurl.com/potscast129
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Medical Disclaimer: The information provided here is not intended to serve as professional medical advice, diagnosis, or treatment. If you have health related issues, please contact a qualified health professional to get the personalized assessment, advice, and treatment that you need. Standing Up to POTS will not be liable for any direct, indirect, or other damages arising from the use of this podcast.

5 snips
Nov 8, 2023 • 38min
Diagnosis & Treatment of MCAS with Dr. Tania Dempsey
Dr. Dempsey dives into the complexities of diagnosing Mast Cell Activation Syndrome (MCAS), emphasizing its multi-system effects. She discusses the importance of addressing comorbidities like POTS. The podcast highlights various treatment options, including Montelukast and Zolair, while stressing the significance of personalized care. Real-life challenges such as long wait times and the intricacies of symptom management are explored, empowering patients with knowledge about their journeys in managing MCAS.

4 snips
Nov 8, 2023 • 43min
Introduction to mast cells and mast cell activation syndrome (MCAS) with Dr. Tania Dempsey
Delve into the fascinating world of mast cells and their role in the immune system. Learn how surgical materials can trigger mast cell activation syndrome and amplify reactions to the environment. The conversation highlights the symptoms of MCAS, particularly in women during hormonal shifts. Discover the link between dysfunctional mast cells and conditions like POTS, emphasizing the need for patient education. Explore the journey of understanding this often-misunderstood syndrome and the importance of advocacy in advancing treatment options.