Mayo Clinic Talks

This episode was recorded June 17, 2020.  To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  J. Taylor Hays, M.D. (@jtaylorhays), Robert Vassallo, M.D. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  Is smoking a risk factor for severe disease in COVID-19? How accurate is the documentation of smoking in COVID-19 cohorts currently published? What role should a smoking history play in the prognosis and management of COVID-19? Drs. Hays and Vassallo discuss the prevalence of smoking worldwide, the impact of documentation, and the role smoking may play in COVID-19. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode was recorded on May 13, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  David J. Rosenman, M.D. (@davidrosenman) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  “At a time when most of the world in one way or another is suffering, it seems relevant to talk about ways to relieve some of that suffering and to help.” Studies have shown that patients value empathy over sympathy, and compassion over empathy. While measures to protect ourselves and understand the spread of COVID-19 and the clinical presentation of the disease are underway, the inconsistency of information across sources brings greater uncertainty for our patients and at times ourselves.  Dr. Rosenman discusses what compassion is and the importance of compassion as a tool to help us and our patients, feel better mentally and physically. He recommends practicing self-compassion and will step through the practices of self-kindness, common humanity, and mindfulness.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode was recorded on May 28, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Edward R. Laskowski, M.D. (@DrEdSportsMed) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  The world was already facing an epidemic of inactivity prior to the emergence and spread of SARS-CoV-2. Some have been able to focus more on self-care and fitness while under stay-at-home measures but with the necessity of social distancing and the widespread closure of fitness centers others have encountered significant challenges. What is the real cost of inactivity? Whether it’s the “Quarantine 15” or the psychological effects of being isolated in a world constantly changing, Dr. Laskowski shares one of the most effective treatments you can recommend to your patients. Deeper Dive: Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging https://doi.org/10.4065/mcp.2011.0252 Strength training: How-to video collection https://www.mayoclinic.org/healthy-lifestyle/fitness/in-depth/strength-training/art-20046031 Physical Activity Guidelines for Americans https://www.hhs.gov/fitness/be-active/physical-activity-guidelines-for-americans/index.html AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode is shared from Mayo Clinic Q&A and was recorded in June, 2020. Guest:  Alexandra P. Wolanskyj-Spinner, M.D. (@apw01) Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) Across the world, one of the biggest changes forced by the COVID-19 pandemic is in the field of education. Programs from kindergarten through postsecondary have rapidly moved to a distance learning model. Online and remote instruction has its own unique challenges, and has required students and educators to be creative to stay connected. On the Mayo Clinic Q&A podcast, Dr. Alexandra Wolanskyj-Spinner, senior associate dean for student affairs at the Mayo Clinic Alix School of Medicine in Minnesota, discusses medical education during the COVID-19 pandemic. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode was recorded on June 5, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Raymund R. Razonable, M.D. (@RazonableMD) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  Up to about 50% of people infected with SARS-CoV-2 are asymptomatic spreaders. About 80% of those who are symptomatic, developing COVID-19, have mild disease displaying dry cough, fever, and fatigue. The resulting 20% of symptomatic patients accounts for those who develop progressive respiratory distress and sometimes multi-organ failure, among other complications. We’re learning more about anosmia, cardiac injury, and “COVID-toes.” What’s known about COVID-19 and SARS-CoV-2 continues to evolve. Dr. Raymund Razonable walks through a recently published update on the management of COVID-19.  Time Stamps: 1:18 - New signs and symptoms of COVID-19. 3:30 - Testing characteristics (sensitivity, specificity, and indications)  of the molecular and serologic testing for SARS-CoV-2 6:22 - Risk factors and the prediction of disease progression for patients hospitalized with COVID-19 9:28 - Hyper-inflammatory syndrome and progression to multi-system organ failure syndrome 10:45 - Multisystem inflammatory syndrome in children (MIS-C) 11:22 - Cardiac complications - 3 factors 12:50 - Diagnosis and treatment of co-infection in hospitalized patients (COVID-19 and flu, COVID-19 and pneumonia) 16:31 - Evidence-based treatment based on the 3 phases of COVID-19 viremic phase, pneumonic phase, hyperinflammation phase 18:06 - Remdesivir update 21:00 - Hydroxychloroquine update 23:25 - Favipiravir and lopinavir-ritonavir update 23:53 - Treatment of the hyperinflammatory phase (sarilumab, tocilizumab, lenzilumab, anakinra,) 27:13 - Convalescent plasma 28:04 - Discharge and social determinants of health 33:40 - Telehealth and remote monitoring 35:40 - Health disparities and telehealth 37:47 - What’s the next development Infectious Disease specialists are looking for in relation to the COVID-19 pandemic? See the article here: A Collaborative Multidisciplinary Approach to the Management of Coronavirus Disease-19 in the Hospital Setting https://doi.org/10.1016/j.mayocp.2020.05.010 AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode was recorded on May 12, 2020. Guest:  James E. Baker, R.R.T., L.R.T. &  Steven R. Holets, R.R.T., L.R.T. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  What are some alternative ventilation strategies we can use to treat patients with COVID-19? James Baker, R.R.T., L.R.T. and Steve Holets, R.R.T., L.R.T. discuss individualizing care, limitations based on device design, and supply chain concerns. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode was recorded on May 27, 2020. Guest:  Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  Patients under 21 who present with fever, lab evidence of inflammation, multisystem involvement, and recent or current SARS-CoV-2 infection fall under the case definition for multisystem inflammatory syndrome. They commonly present with persistent fever and gastrointestinal symptoms and concerningly, shock. Why are we seeing disproportionate rates in children of racial and ethnic minorities? Dr. Nipunie Rajapaske concisely covers what’s known about this syndrome and the data supporting its emergence as a post-infection complication. CDC Health Advisory on Multisystem Inflammatory Syndrome in Children (MIS-C) https://emergency.cdc.gov/han/2020/han00432.asp An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study https://doi.org/10.1016/S0140-6736(20)31103-X AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode is shared from Mayo Clinic Q&A and was recorded on May 26, 2020. Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) According to the Centers for Disease Control and Prevention, the most common mode of transmission for COVID-19 is through close contact from person to person. While it is possible that someone can get COVID-19 by touching a surface or object that has the virus on it and then touching their own mouth, nose or possibly their eyes, this isn’t thought to be the main way the virus spreads. On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, discusses virus transmission and steps to take to keep yourself safe. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode was recorded May 22, 2020 To claim credit visit: https://ce.mayo.edu/covid19podcast   Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  SARS-CoV-2, as an RNA virus, has marked capacity for mutation and recombination events. How do we build an efficacious and safe vaccine against it? How could we safely speed up development? Is a vaccine neutralizing the spike protein enough? Dr. Greg Poland returns to give you an update from the front lines of research on vaccine development and ongoing clinical trials. Dr. Poland’s Editorial: Tortoises, hares, and vaccines: A cautionary note for SARS-CoV-2 vaccine development https://doi.org/10.1016/j.vaccine.2020.04.073   'I Have A Dream' Speech, In Its Entirety https://www.npr.org/2010/01/18/122701268/i-have-a-dream-speech-in-its-entirety Our 'Fierce Urgency of Now' -  Secretary Kathleen Sebelius https://obamawhitehouse.archives.gov/blog/2013/08/26/our-fierce-urgency-now King Legacy: 'Fierce Urgency of Now' Exists Today - Terri Moon Cronk https://www.defense.gov/Explore/Features/Story/Article/2059480/king-legacy-fierce-urgency-of-now-exists-today/ AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode was recorded May 21, 2020 Visit the program site here:  https://www.uscovidplasma.org To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Michael J. Joyner, M.D. (@DrMJoyner) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  Convalescent plasma as a passive immunity strategy is not new. What nuances apply for it’s application to treating COVID-19? Is it safe? Is it efficacious? Dr. Michael Joyner, Principal Investigator for Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19, discusses what’s known about this treatment option, information that’s currently being gathered, and how you can get involved. AABB Coronavirus Resources: http://www.aabb.org/advocacy/regulatorygovernment/Pages/AABB-Coronavirus-Resources.aspx AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.