Mayo Clinic Talks

Mayo Clinic
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Aug 21, 2020 • 15min

COVID-19 Miniseries Episode 48: Answers from the Lab - Neutralizing Antibody Assay, Explained

This episode is shared from Answers from the Lab and was originally published June 30, 2020.  Guest: John R. Mills, Ph.D.  Host: Bobbi S. Pritt, M.D. (@ParasiteGal)  John Mills, Ph.D., is the co-director of the Neuroimmunology Laboratory at Mayo Clinic and the scientist who oversaw the development and validation of the new neutralizing antibody assay. Today he joins us to explain what the neutralizing antibody assay is, why it is different than other COVID-19 tests, and the science and innovation behind these efforts.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
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Aug 19, 2020 • 13min

Answers from the Lab: Future of COVID-19 Laboratory Testing

This episode is shared from Answers from the Lab and was originally published June 25, 2020.  Guest: William G. Morice, II M.D., Ph.D. (@moricemdphd)  Host: Bobbi S. Pritt, M.D. (@ParasiteGal)  William Morice, II, M.D., Ph.D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. In this episode, Dr. Morice discusses the future of testing for COVID-19, predicting who would be at the highest risk for severe disease, and challenges with existing diagnostics.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd 
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Aug 18, 2020 • 26min

Sorting Out Knee Pain and Treatment Opportunities

Guest: Daniel B. Saris, M.D., Ph.D. (@sarisnl)  Host: Darryl S. Chutka, M.D. (@ChutkaMD)  With over 12 million outpatient visits annually in association with knee pain, it’s a common presentation in primary care. Dr. Daniel Saris discusses what questions we should be asking our patients, when to order imaging studies, and the common causes of pain broken down by age demographic. He’ll also discuss stem cell therapy, who is a good candidate, and who isn’t.  Episode transcript: https://mcdn.podbean.com/mf/web/cjj292/Ep_183-Sorting_Out_Knee_Pain_and_Treatment_Opportunities.pdf Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
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Aug 17, 2020 • 13min

COVID-19 Miniseries Episode 47: Answers from the Lab - Serology Testing for COVID-19

This episode is shared from Answers from the Lab and was originally published June 16, 2020.  Guest: Elitza Theel, Ph.D. (@ElliTheelPhD)  Host: Bobbi S. Pritt, M.D. (@ParasiteGal)  Elitza Theel, Ph.D., Laboratory Director of the Infectious Diseases Serology Laboratory at Mayo Clinic, led the efforts to evaluate and implement the serologic antibody test for COVID-19. She gives an overview of Mayo Clinic’s COVID-19 antibody test, as well as the role of antibody testing during the pandemic, and how sensitivity, specificity, and prevalence play a large role in the positive predictive value of a test.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd 
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Aug 11, 2020 • 29min

COVID-19 Miniseries Episode 46: Physician Leaders and the Science of Health Care Delivery

This episode was recorded August 6, 2020.  To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest: Lisa A. McGee, M.D.  Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  What are population centered care and health? How do we best use rationed resources within our health care system to most effectively meet these needs? Dr. Lisa McGee discusses the Science of Health Care Delivery,  the impact mass media messages have had on the current COVID-19 pandemic, and how we can use the information we have about population centered health to address key influential components of SARS-CoV-2’s continual spread.  Suggested Readings:  The effect of public health measures on the 1918 influenza pandemic in U.S. cities  https://doi.org/10.1073/pnas.0611071104  Public health interventions and epidemic intensity during the 1918 influenza pandemic  https://doi.org/10.1073/pnas.0610941104  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
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Aug 4, 2020 • 30min

COVID-19 Miniseries Episode 45: There Is No Win-Win

This episode was recorded on June 26, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Pritish K. Tosh, M.D. (@DrPritishTosh)  Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  Novel viruses causing outbreaks tend to do one of three things: disappear completely, become endemic in certain areas, or roll through populations with ongoing transmission until herd immunity is achieved or an effective vaccine is developed. Dr. Pritish Tosh states, “If natural infection doesn’t cause long-lasting protective immunity or the vaccines don’t do the same, this thing could be with us for a long time.” Take a walk through the past 100 years of pandemics as Dr. Tosh draws comparisons and lessons learned.  The Economist - The Grim Calculus  https://www.economist.com/leaders/2020/04/02/covid-19-presents-stark-choices-between-life-death-and-the-economy  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
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Jul 28, 2020 • 40min

COVID-19 Miniseries Episode 44: Supply Chain Vulnerability - Why Don’t We Have Enough PPE?

This episode was recorded on June 26, 2020.  To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Pritish K. Tosh, M.D. (@DrPritishTosh)  Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  “Everybody has a plan until they get punched in the mouth.” - Mike Tyson  Thin margins and economies of scale help lower costs but can create significant vulnerabilities. Often calculations of lives lost in the event of a shortage or costs to stockpile may not be factored in when sourcing supplies. Healthcare supply chain practices over decades have lead to significant weak points in our supply chains for some vital materials and we often have no view of this until it’s too late.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
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Jul 21, 2020 • 24min

COVID-19 Miniseries Episode 43: Healthcare Disparities and Systemic Racism

This episode was recorded June 25, 2020.  To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Kenneth G. Poole, Jr. M.D., M.B.A. (@KPooleMD)  Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  Black, Latino, and Native American populations have been disproportionately affected by COVID-19. Underlying health inequities have been a major contributor. Dr. Kenneth Poole discusses social determinants of health and how these combined with systemic racism, predating COVID-19, laid the groundwork for the suffering we’re seeing unfold. What can we do to address it effectively?  COVID-19 and African Americans - Clyde Yancy  https://jamanetwork.com/journals/jama/fullarticle/2764789  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
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Jul 14, 2020 • 29min

COVID-19 Miniseries Episode 42: The Impact of Care Disruption for Patients with Non-Emergent Needs

This episode was recorded May 19, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Sidna M. Tulledge-Scheitel, M.D., M.P.H. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  The COVID-19 pandemic has caused waves of care disruption for people around the world. What patient populations have faced unique risks? What signs of impact from the temporary restriction of medical outpatients services are we seeing? Dr. Tulledge-Scheitel shares what’s being seen at Mayo Clinic, what she anticipates we’ll be seeing in the coming months, and what she’d do should this need arise again in the future. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
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Jul 9, 2020 • 43min

COVID-19 Miniseries Episode 41: Breaking Down the Impact of Smoking in COVID-19 Part 2

This episode was recorded June 17, 2020.  To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:   J. Taylor Hays, M.D. (@jtaylorhays), Robert Vassallo, M.D. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)  Is the act of smoking a risk factor for transmission? Does nicotine protect against severe COVID-19? Dr. Hays and Dr. Vassallo discuss what is currently known about the risks of smoking in regard to COVID-19 and treatment of patients who smoke, during the pandemic. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

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