This episode was recorded on May 27, 2020.

Guest: Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)

Patients under 21 who present with fever, lab evidence of inflammation, multisystem involvement, and recent or current SARS-CoV-2 infection fall under the case definition for multisystem inflammatory syndrome. They commonly present with persistent fever and gastrointestinal symptoms and concerningly, shock. Why are we seeing disproportionate rates in children of racial and ethnic minorities? Dr. Nipunie Rajapaske concisely covers what’s known about this syndrome and the data supporting its emergence as a post-infection complication.

CDC Health Advisory on Multisystem Inflammatory Syndrome in Children (MIS-C)
https://emergency.cdc.gov/han/2020/han00432.asp

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study
https://doi.org/10.1016/S0140-6736(20)31103-X

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

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COVID-19 Miniseries Episode 34: Multi-System Inflammatory Syndrome (MIS-C) in Pediatric Patients