Mayo Clinic Talks

Host: Denise M. Dupras, M.D., Ph.D. Guest: Saad J. Kenderian, M.B., Ch.B. Dr. Saad Kenderian discusses the use of CAR-T cell therapy, a groundbreaking treatment that genetically modifies a patient's T-cells to target and destroy cancer cells, particularly in blood cancers like leukemia and lymphoma. He highlights the importance of identifying eligible patients, monitoring treatment response, and applying genomics to guide the future of personalized cancer immunotherapy. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

Host: Danielle O’Laughlin, PA-C, MS Guest: Jenna Wygant, APRN, CNP, DNP In this episode, Jenna Wygant, APRN, CNP, DNP, walks listeners through the most common types of vaginitis, helping providers to confidently differentiate between them. We’ll explore the definitions, causes, risk factors, signs and symptoms, as well as diagnostic methods and treatment options for each condition. Comparing the features of these common vaginitis conditions will be emphasized throughout the episode. By the end of this podcasts, listeners will be able to: Differentiate common vaginitis conditions. Understand the definition, causes/risk factors, signs and symptoms, diagnosis, and treatment for common vaginitis conditions. Identify features that help compare common vaginitis conditions. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP Guest: Jenna Johnson, APRN, CNP, DNP In this episode, we focus on understanding and differentiating common vulvar conditions with guest Jenna Johnson, APRN, CNP, DNP. We will cover how to recognize conditions such as risk factors, signs and symptoms, and gain insight into how these conditions are diagnosed and treated. We’ll also highlight helpful ways to compare these common vulvar health conditions. By the end of this podcast, listeners will be able to: Differentiate common vulvar conditions. Understand the definition, causes/risk factors, signs and symptoms, diagnosis, and treatment for common vulvar conditions. Identify features that help compare common vulvar conditions. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS Guest: Jenna Wygant, APRN, CNP, DNP Guest, Jenna Wygant, APRN, CNP, DNP, joins us to explore the full spectrum of contraception options - from natural family planning to non-hormonal and hormonal methods. For each type of contraception, an understanding of how each type works, their efficacy, and the potential risks and benefits will be covered. We also break down the different types of emergency contraception and considerations to review when consulting with patients. By the end of this podcast, listeners will be able to:  Define natural family planning, non-hormonal, and hormonal contraceptives. Understand the use, efficacy, mechanism of action, and risks and benefits for the different types of contraception. Explain the types and uses of emergency contraception. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP Guest: Jissy Cyriac, M.D. In this episode, guest Jissy Cyriac, M.D., will walk us through the complexities of menstrual health by comparing a normal menstrual cycle with the key causes of abnormal uterine bleeding and menopause. Recognizing the signs, symptoms, and treatment options for conditions like endometriosis, adenomyosis, and endometrial hyperplasia. Plus, we’ll highlight essential buzzwords, the gold-standards and helpful ways to help solidify understanding of key aspects of gynecologic health for menstrual cycles, abnormal uterine bleeding causes, and menopause. By the end of this podcasts, listeners will be able to: Differentiate the normal menstrual cycle versus causes of abnormal uterine bleeding and menopause. Recognize the signs and symptoms, diagnosis, and treatment options for a few of the abnormal uterine bleeding causes including endometriosis, adenomyosis, and endometrial hyperplasia. Identify BUZZ words, gold standards, and helpful ways to remember components of the normal menstrual cycle, abnormal uterine bleeding causes, and menopause. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP Guest: Danielle O’Laughlin, PA-C, MS In this episode, along with host/guest Danielle O’Laughlin, PA-C, MS, we will discuss benign, inflammatory breast conditions. We will cover how to differentiate between common issues such as mastitis, breast abscess, fat necrosis, galactorrhea, and gynecomastia. We’ll walk through the key signs and symptoms to watch for and explore how each condition is diagnosed and treated. This episode offers valuable insights into these non-cancerous yet very important conditions. By the end of this podcasts, listeners will be able to: Differentiate the benign, inflammatory breast conditions including mastitis, breast abscess, fat necrosis, galactorrhea, and gynecomastia. Recognize the signs and symptoms for benign, inflammatory breast conditions. Summarize the diagnosis and treatment options for benign, inflammatory breast conditions. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Darryl S. Chutka, M.D. Guests: Cadman L. Leggett, M.D., and Chamil C. Codipilly, M.D. Occasional heartburn from gastroesophageal reflux is usually nothing more than an occasional nuisance for most patients.  However, when the reflux becomes chronic, it can become more serious.  One complication is Barrett’s esophagus. On occasion, Barrett’s can develop into esophageal adenocarcinoma, an aggressive malignancy with a survival rate of only around 20% at 5 years.  Although usually seen in those with chronic acid reflux, Barrett’s can occasionally occur in those without any clinical evidence of acid reflux.  When should a patient with acid reflux receive an upper endoscopy?  What’s the significance of finding Barrett’s esophagus on an endoscopy?  How often does Barrett’s develop into esophageal cancer and does treatment prevent this from happening?  In this podcast, these are just some of the questions I’ll be asking our guests, Cadman L. Leggett, M.D., and Chamil C. Codipilly, M.D., both from the Division of Gastroenterology and Hepatology at the Mayo Clinic as we discuss Barrett’s Esophagus. Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Denise M. Dupras, M.D., Ph.D. Guest: Michael Zimmer, Ph.D., Director of Rare Diseases at Moderna Therapeutics This episode of Genes & Your Health welcomes Dr. Michael Zimmer from Moderna Therapeutics, who discusses how mRNA technology is being applied to treat rare genetic diseases, especially liver-based metabolic disorders. Dr. Zimmer explains how mRNA can help the body produce missing proteins, the challenges of delivering these therapies, and the promise they hold for previously untreatable conditions. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

Host: Darryl S. Chutka, M.D. Guest: John Haney, M.D., M.P.H. Lung transplantation remains a very viable option for patients with end-stage pulmonary disease who no longer respond to medical management. Over 5,000 lung transplants are performed annually around the world. However, its estimated that over 10 times this number are candidates and awaiting a transplant. A shortage of organs remains the major limiting factor. What are the common indications and who’s a candidate for a lung transplant? How are patients prioritized and chosen? What advances have been made in the field and what challenges remain? Finally, what role does the primary care clinician play in lung transplantation? I’ll be discussing these questions and more with my guest, Jack Haney, M.D., M.P.H., chair of cardiothoracic surgery at the Jacksonville campus of the Mayo Clinic. The topic for this podcast is “Lung Transplantation”. Learn more about this Transplant Series:  Mayo Clinic Talks: Donate Life: Transplantation Series | Mayo Clinic School of Continuous Professional Development Connect with Mayo Clinic’s Transplant Center online at https://mayoclinic.org/transplant or on X @MayoTransplant. To learn more and register to be an organ donor please visit https://careinfo.mayoclinic.org/organ-donation. Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Denise M. Dupras, M.D., Ph.D. Guest: Heidi Nelson, M.D., Emeritus Chair of the Department of Surgery and past Chair of the Division of Colon & Rectal Surgery at Mayo Clinic in Rochester Guest: Jaeyun Sung, Ph.D., Associate Professor of Biomedical Informatics and Senior Associate Consultant II in the Department of Quantitative Health Sciences, Mayo Clinic Rochester This episode of Genes & Your Health presents the results of the Gut Microbiome Wellness Index 2 study, which examines the differences between the gut microbiomes of healthy and disease-affected populations. Drs. Nelson and Sung discussed a potential future where a stool gut microbiome profile could be used as a barometer of general gut health and outlined how the microbiome can be altered and used to predict overall health.  They also covered factors that can contribute to returning the gut microbiome to healthy status after a disruption. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts