
Mayo Clinic Talks
Timely consultations relevant for family medicine, primary care, and general internal medicine topics for physicians, nurse practitioners, physician assistants, and residents. Offering CME credit for most episodes at https://ce.mayo.edu/podcast. Produced by @MayoMedEd.
Latest episodes

Sep 29, 2022 • 32min
Genes & Your Health Edition: Breast Cancer & SNPs- What Are They & What Do We Know?
Guests: Sandhya Pruthi, M.D. (@DrSandhyaPruthi)
Host: Denise M. Dupras, M.D., Ph.D.
What is precision prevention? As providers, what can we do to best determine who is at high risk for breast cancer, and when to make appropriate decisions about interventions to reduce an individual’s risk for getting breast cancer? In this episode of our Genes & Your Health edition from the Center for Individualized Medicine, we will learn more about breast cancer, breast cancer genes and the role of single nucleotide polymorphisms (SNPs) in breast cancer risk assessment. Our guest is Sandhya Pruthi, M.D., a Mayo Clinic physician in breast disease and a consultant and Professor of Medicine in the Department of General Internal Medicine in Rochester, Minnesota.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Sep 27, 2022 • 21min
Helping Your Patients Live Younger Longer
Host: Darryl S. Chutka, M.D. @ChutkaMD
Guest: Stephen Kopecky, M.D.
Most of us want to live longer, but we want to live a healthy life and avoid the many health problems associated with growing older. Many of the health issues associated with aging have significant morbidity and have the potential to significantly affect our quality of life. Do we know how to avoid these health problems and stay healthy into our older ages? What should we be advising our patients to help them live younger longer? We’ll discuss these questions with our guest today, Stephen Kopecky, M.D., a preventive cardiologist at the Mayo Clinic.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Sep 22, 2022 • 34min
Genes & Your Health Edition: Polycystic Kidney Disease & Genetic Testing - Aiming for Accurate Diagnosis
Guest: Fouad T. Chebib, M.D.
Host: Denise M. Dupras, M.D., Ph.D.
What is polycystic kidney disease? Is it all genetic? As providers, what should we be considering and what patients should we think about screening with genetic testing? Join this episode of our Genes & Your Health edition from the Center for Individualized Medicine to learn more about the role of genes in polycystic kidney disease. This episode features Fouad T. Chebib, M.D., a Mayo Clinic nephrologist from Jacksonville, Florida, whose specialty is in polycystic kidney disease.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Sep 20, 2022 • 22min
Genes & Your Health Edition: Exposomics - The Next Frontier
Guest: Konstantinos N. Lazaridis, M.D.
Host: Denise M. Dupras, M.D., Ph.D.
What does the exposome mean? In this episode, we will define the exposome and explore how assessing exposures in an organized fashion will help us better understand the gene environment interaction. The guest for this episode of our Genes & Your Health edition from the Center for Individualized Medicine is Konstantinos N. Lazaridis, M.D., a Mayo Clinic physician in the Division of Gastroenterology and Hematology, as well as the Bernard and Edith Waterman Director, Microbiome Program, Center for Individualized Medicine and Carlson and Nelson Endowed Director, Center for Individualized Medicine.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Sep 13, 2022 • 29min
Monoclonal Gammopathy of Undetermined Significance (MGUS)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Guest: Wilson I. Gonsalves, M.D.
Monoclonal gammopathies represent abnormal proteins produced by plasma cells. The most common monoclonal gammopathy is monoclonal gammopathy of undetermined significance or MGUS. While MGUS itself is not a malignancy and doesn’t require treatment, patients with MGUS have an increased risk of developing a variety of hematologic malignancies and therefore do require surveillance. The topic for today’s podcast is monoclonal gammopathy of undetermined significance and our guest is Wilson I. Gonsalves, M.D., a hematologist and oncologist from the Division of Hematology at the Mayo Clinic. We’ll discuss how to diagnose MGUS, who is more likely to develop this condition and how patients with it should be followed.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Sep 6, 2022 • 22min
Mayo Clinic Q&A: Updated COVID-19 boosters target omicron variants
This episode is shared from Mayo Clinic Q&A and was recorded on August 31, 2022
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
The first significant change to COVID-19 vaccines since their rollout came this week as the Food and Drug Administration granted emergency use authorization for updated Moderna and Pfizer COVID-19 boosters aimed at the omicron variants. The Centers for Disease Control and Prevention (CDC) also signed off on the recommendation, clearing the way for the new COVID-19 booster to be administered.
The new boosters are bivalent vaccines, meaning they target more than one strain of the virus. The new formulation targets the BA.4 and BA.5 omicron variants, in addition to the original coronavirus strain. BA.5 is responsible for nearly 90% of all new COVID-19 cases in the U.S., according to the CDC.
The Pfizer bivalent booster is approved for people 12 and up if they have already received their primary COVID-19 vaccine series and it has been at least two months since their last vaccine dose. The Moderna bivalent booster is available on the same timeline to people 18 and up.
"This booster recommendation is in anticipation that there will be yet another surge as college students, grade school and high school students are gathering back together," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "We're also preparing for cooler weather, meaning more indoor activities, family gatherings and the holidays — often without masks, unfortunately. We still need to take COVID seriously."
Another big concern for vaccine experts is the upcoming flu season. The Southern Hemisphere is often an indicator of what's to come for the U.S. Australia's flu season exceeded its five-year average, particularly affecting children under age 5, according to a recent report.
Experts worry that the relaxing of masking and social distancing recommendations that were in place for COVID-19 purposes the past two winters will be a factor. These measures also protected people from the flu.
"When cold weather moves us indoors, a high viral circulation occurs in schools and other indoor settings. I think we are very likely to see a bad flu year," says Dr. Poland. "Now I know we've been predicting that for two years, but for the most part, people wore masks and it didn't happen. I don't think that'll be the case this year. People are not wearing masks, and we are very likely to get hit hard by influenza."
On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news and touches on other news, including monkeypox, polio and the upcoming flu season.

4 snips
Sep 6, 2022 • 22min
Plantar Fasciitis: Best Step Forward
Host: Joshua D. Luciew, P.A.-C.
Guest: Arthur J. De Luigi, D.O., M.H.A. (@DrDeLuigi, https://twitter.com/drdeluigi)
Heel and foot pain can be a burdensome symptom for our patients, as discomfort can be experienced with each step they take, hindering locomotion.
Many different patient populations are required to be on their feet for their job or for various wellness goals, which can exacerbate their painful heel and foot or deter them from exercise.
In this episode, we will explore the most common cause of heel and foot pain: plantar fasciitis. Listeners will learn from a Mayo Clinic specialist in Physical Medicine and Rehabilitation how plantar fasciitis develops, how it is properly diagnosed, and learn the best approaches for treatments of this condition to help patients resume their previous physical activities, pain-free.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Aug 30, 2022 • 21min
Peripheral Neuropathies: On Pins and Needles
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Guest: Julie A. Khoury, M.D.
Peripheral neuropathy is a relatively common neurologic condition we frequently see in primary care. Some patients may describe the symptoms as paresthesias and they represent a minor nuisance, however others may have very painful dysesthesias. Since some peripheral neuropathies are reversible, we need to know when to suspect a peripheral neuropathy, how to evaluate patients who have them and the possible treatment options. We’ll discuss peripheral neuropathies in this podcast with Julie A. Khoury, M.D., a neurologist at the Mayo Clinic in Phoenix, Arizona.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Aug 23, 2022 • 20min
Kidney Stones: This Too Shall Pass
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Guest: Ivan E. Porter, II M.D.
Kidney stones are quite common and represent one of the most common disorders of the urinary system. When symptomatic, stones are relatively easy to diagnose as they tend to cause a very characteristic clinical presentation. While most stones will pass through the urinary system, others will require a variety of treatment options. The topic for today’s podcast is kidney stones and we’ll discuss the diagnosis, management, and prevention of stones with Ivan E. Porter, II M.D., a nephrologist at the Mayo Clinic.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Aug 16, 2022 • 22min
Managing Hypertension in the Elderly
Guest: Sandra J. Taler, M.D.
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
It’s estimated that over 70% of those 65 and older have hypertension and there’s good evidence to show that less than half of these elderly individuals are adequately controlled. While there are many similarities between hypertension in the elderly and the general population, there are also some important differences. The elderly are more likely to have systolic hypertension, take multiple medications and they’re more likely to experience more frequent and serious adverse drug reactions. In this podcast, we’ll learn more about hypertension in the elderly from Sandra J. Taler, M.D., a nephrologist and hypertension specialist at the Mayo Clinic in Rochester, Minnesota.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
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