Mayo Clinic Talks

Guest: Matthew J. Ferber, Ph.D. Host: Darryl S. Chutka, M.D. [@chutkaMD] Over the past decade or so, we’ve learned a great deal about the human genome, and this has allowed us to determine which medical conditions our patients are at an increased risk of developing and which medications may be best suited for their medical problems. In addition to the clinical genetic tests we use in our practice, direct to consumer home genetic testing has become extremely popular. This podcast will review home genetic testing and what information patients can expect with these tests, whether the information they receive is accurate and how home genetic testing differs from the genetic tests we order. Our guest is Matthew J. Ferber, Ph.D., a clinical molecular geneticist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Host: Darryl S. Chutka, M.D. (@chutkaMD) https://twitter.com/ChutkaMD Guest: Kurt A. Kennel, M.D. Hip fractures have had a major impact on our healthcare system with an economic burden estimated to be over $20 billion per year. Due to the increasing age of our population, they’ll have an even greater impact in the future. In addition to the economic burden, hip fractures often result in major changes to one’s lifestyle. As a result, the detection, prevention and management of osteoporosis becomes an important health strategy. The topic for this podcast is osteoporosis and our guest is Kurt A. Kennel, MD., a Mayo Clinic Endocrinologist, and specialist in bone metabolism. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Guest: Pritish K. Tosh, M.D. (@DrPritishTosh) Host: Darryl S. Chutka, M.D. (@chutkaMD) The COVID-19 pandemic exposed the vulnerability of the medical product supply chain and its impact on providing optimal healthcare. The spread of the disease was accompanied by not only shortages of personal protective equipment but also medications and many other products we depend on every day in our clinical practice. We’ve learned that we cannot provide adequate or timely health care when there are shortages of important products. As a result, the health of our patients and healthcare providers has been endangered. It’s also resulted in a rationing of care and an increased risk of error as we’re forced to use sub-standard or replacement products. It’s caused us to look for new solutions to reduce our medical supply chain vulnerabilities. Our guest for this podcast is Pritish K. Tosh, M.D., an infectious disease specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  Twitter Handles: (@chutkaMD); https://twitter.com/ChutkaMD  (@DrPritishTosh); https://twitter.com/drpritishtosh

Guest: John B. Kisiel, M.D. (@DrJohnKisiel) Host: Darryl S. Chutka, M.D. (@chutkaMD) Colon polyps are relatively common in our population and, in most cases, are relatively easily found and removed, thereby reducing one's risk of developing colorectal cancer. What are the various types of colon polyps and which polyps have a greater tendency to become malignant? How long does it take a polyp to develop into colon cancer and how often does colonoscopy miss polyps?  These are just some of the topics we’ll discuss in today’s podcast. Our guest is John B. Kisiel, M.D., a gastroenterologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Host: Denise M. Dupras, M.D., Ph.D. Guest: Andres J. Acosta, M.D., Ph.D. (@dr_aac) The obesity epidemic continues to escalate in the United States and obesity rates are increasing around the world. It is estimated that by 2030, 50% of adults and 25% of children worldwide will be obese. Patients are the interaction of their genetics and environment; this episode explores the importance of understanding the mechanisms behind food intake regulation and weight to develop individualized therapies to treat obesity. Our guest for this episode is Andres J. Acosta, M.D., Ph.D., a physician-scientist at Mayo Clinic in Rochester, Minnesota. He is also an assistant professor of medicine at Mayo Clinic College of Medicine and Science, and principal investigator of the Precision Medicine for Obesity Laboratory.

Guest: Elizabeth (Ebbie) A. Stewart, M.D. Host: Darryl S. Chutka, M.D. Uterine fibroids are the most common tumor of the female reproductive tract and women who are approaching menopause are at greatest risk for having them. In most cases, they don’t produce symptoms and only a minority of women require treatment. The topic for this podcast is uterine fibroids and we’ll discuss how fibroids can be diagnosed, their most common symptoms, who requires treatment and some of the latest treatment options with our guest, Elizabeth A. Stewart, M.D., from the Department of Obstetrics and Gynecology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Guest:   Alexandre Gaspar Maia, Ph.D. (@gasparma1a) Host: Denise M. Dupras, M.D., Ph.D. Epigenomics is a fascinating field in which researchers chart the locations and understand the functions of all chemical tags that mark the genome. The epigenome is the first boundary from the exterior world to our DNA sequence, and it can change dramatically. This episode discusses the state of the art of epigenomics analysis and the epigenome in the context of specific cells. Additionally, it explores the future of epigenomics for individualized medicine and in better understanding genetics of treatment resistance. The guest for this episode is Alexandre Gaspar Maia, Ph.D., an assistant professor in the Functional Genomics Laboratory at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Host: Edward R. Laskowski, M.D Guest: Anthony A. Stans, M.D. The evaluation and treatment of scoliosis is an area that has created some controversy over the years.  Should we be screening kids in school?  When do we brace kids with scoliosis?  And what are the indications for surgery? To help us answer these questions and more, I am delighted to welcome Anthony A. Stans, M.D., a consultant in the Division of Pediatric Orthopedic Surgery with special interest in the treatment of spinal deformity.  He is past Chair of the Mayo Clinic Division of Pediatric Orthopedic Surgery and past Surgeon in Chief for the Mayo Clinic Children’s Center. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Guest: Bradley F. Boeve, M.D. Host: Denise M. Dupras, M.D., Ph.D. Family history is so important in deciphering genetic causes for neurodegenerative disorders. As we study polygenetic situations, we are learning that often it is not just one gene, but the contribution of multiple genes that lead to the presentation of a patient with cognitive or brain function deterioration that occurs at a variable rate. In this episode, we discuss genes and neurodegenerative brain disease, and our guest is Bradley F. Boeve, M.D., a consultant in the Department of Neurology and the Center for Sleep Medicine, as well as a professor of neurology at the Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Host: Darryl S. Chutka, M.D. @chutkaMD Guest: Jason C. Sluzevich, M.D. Psoriasis is a somewhat atypical dermatologic condition which can come and go over time. In many, there may be seasonal effects and in some, psoriasis can have an associated arthritis. It has a characteristic distribution and while it has no cure, there are a variety of established and new treatment options. In this podcast, we’ll review how to diagnose psoriasis, its characteristic appearance, its associated arthritis, and management strategies with Jason C. Sluzevich, M.D., a dermatologist from the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.