Guest: Fouad T. Chebib, M.D. Host: Denise M. Dupras, M.D., Ph.D. What is polycystic kidney disease? Is it all genetic? As providers, what should we be considering and what patients should we think about screening with genetic testing? Join this episode of our Genes & Your Health edition from the Center for Individualized Medicine to learn more about the role of genes in polycystic kidney disease. This episode features Fouad T. Chebib, M.D., a Mayo Clinic nephrologist from Jacksonville, Florida, whose specialty is in polycystic kidney disease. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Konstantinos N. Lazaridis, M.D. Host: Denise M. Dupras, M.D., Ph.D. What does the exposome mean? In this episode, we will define the exposome and explore how assessing exposures in an organized fashion will help us better understand the gene environment interaction. The guest for this episode of our Genes & Your Health edition from the Center for Individualized Medicine is Konstantinos N. Lazaridis, M.D., a Mayo Clinic physician in the Division of Gastroenterology and Hematology, as well as the Bernard and Edith Waterman Director, Microbiome Program, Center for Individualized Medicine and Carlson and Nelson Endowed Director, Center for Individualized Medicine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Host: Darryl S. Chutka, M.D. (@ChutkaMD) Guest: Wilson I. Gonsalves, M.D. Monoclonal gammopathies represent abnormal proteins produced by plasma cells. The most common monoclonal gammopathy is monoclonal gammopathy of undetermined significance or MGUS. While MGUS itself is not a malignancy and doesn’t require treatment, patients with MGUS have an increased risk of developing a variety of hematologic malignancies and therefore do require surveillance. The topic for today’s podcast is monoclonal gammopathy of undetermined significance and our guest is Wilson I. Gonsalves, M.D., a hematologist and oncologist from the Division of Hematology at the Mayo Clinic. We’ll discuss how to diagnose MGUS, who is more likely to develop this condition and how patients with it should be followed.  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

This episode is shared from Mayo Clinic Q&A and was recorded on August 31, 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The first significant change to COVID-19 vaccines since their rollout came this week as the Food and Drug Administration granted emergency use authorization for updated Moderna and Pfizer COVID-19 boosters aimed at the omicron variants. The Centers for Disease Control and Prevention (CDC) also signed off on the recommendation, clearing the way for the new COVID-19 booster to be administered. The new boosters are bivalent vaccines, meaning they target more than one strain of the virus. The new formulation targets the BA.4 and BA.5 omicron variants, in addition to the original coronavirus strain. BA.5 is responsible for nearly 90% of all new COVID-19 cases in the U.S., according to the CDC. The Pfizer bivalent booster is approved for people 12 and up if they have already received their primary COVID-19 vaccine series and it has been at least two months since their last vaccine dose. The Moderna bivalent booster is available on the same timeline to people 18 and up. "This booster recommendation is in anticipation that there will be yet another surge as college students, grade school and high school students are gathering back together," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "We're also preparing for cooler weather, meaning more indoor activities, family gatherings and the holidays — often without masks, unfortunately. We still need to take COVID seriously." Another big concern for vaccine experts is the upcoming flu season. The Southern Hemisphere is often an indicator of what's to come for the U.S. Australia's flu season exceeded its five-year average, particularly affecting children under age 5, according to a recent report. Experts worry that the relaxing of masking and social distancing recommendations that were in place for COVID-19 purposes the past two winters will be a factor. These measures also protected people from the flu. "When cold weather moves us indoors, a high viral circulation occurs in schools and other indoor settings. I think we are very likely to see a bad flu year," says Dr. Poland. "Now I know we've been predicting that for two years, but for the most part, people wore masks and it didn't happen. I don't think that'll be the case this year. People are not wearing masks, and we are very likely to get hit hard by influenza." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news and touches on other news, including monkeypox, polio and the upcoming flu season.  

Host: Joshua D. Luciew, P.A.-C. Guest: Arthur J. De Luigi, D.O., M.H.A. (@DrDeLuigi, https://twitter.com/drdeluigi) Heel and foot pain can be a burdensome symptom for our patients, as discomfort can be experienced with each step they take, hindering locomotion. Many different patient populations are required to be on their feet for their job or for various wellness goals, which can exacerbate their painful heel and foot or deter them from exercise. In this episode, we will explore the most common cause of heel and foot pain: plantar fasciitis. Listeners will learn from a Mayo Clinic specialist in Physical Medicine and Rehabilitation how plantar fasciitis develops, how it is properly diagnosed, and learn the best approaches for treatments of this condition to help patients resume their previous physical activities, pain-free. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Host: Darryl S. Chutka, M.D. (@ChutkaMD) Guest: Julie A. Khoury, M.D. Peripheral neuropathy is a relatively common neurologic condition we frequently see in primary care. Some patients may describe the symptoms as paresthesias and they represent a minor nuisance, however others may have very painful dysesthesias. Since some peripheral neuropathies are reversible, we need to know when to suspect a peripheral neuropathy, how to evaluate patients who have them and the possible treatment options. We’ll discuss peripheral neuropathies in this podcast with Julie A. Khoury, M.D., a neurologist at the Mayo Clinic in Phoenix, Arizona. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Host: Darryl S. Chutka, M.D. (@ChutkaMD) Guest: Ivan E. Porter, II M.D. Kidney stones are quite common and represent one of the most common disorders of the urinary system. When symptomatic, stones are relatively easy to diagnose as they tend to cause a very characteristic clinical presentation. While most stones will pass through the urinary system, others will require a variety of treatment options. The topic for today’s podcast is kidney stones and we’ll discuss the diagnosis, management, and prevention of stones with Ivan E. Porter, II M.D., a nephrologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Sandra J. Taler, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) It’s estimated that over 70% of those 65 and older have hypertension and there’s good evidence to show that less than half of these elderly individuals are adequately controlled. While there are many similarities between hypertension in the elderly and the general population, there are also some important differences. The elderly are more likely to have systolic hypertension, take multiple medications and they’re more likely to experience more frequent and serious adverse drug reactions. In this podcast, we’ll learn more about hypertension in the elderly from Sandra J. Taler, M.D., a nephrologist and hypertension specialist at the Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Host: Sanjeev (Sanj) Kakar, M.D. (sanjkakar) Guest: William W. Cross, III, M.D. (@WilliamCross3MD) Did you know the lifetime prevalence of generalized low back pain is estimated at 60% to 70% in industrialized countries? Often overlooked, the sacroiliac or SI joint can cause approximately one third of these cases. How do you determine the difference between the two? In this week’s podcast, we discuss the diagnosis of SI joint dysfunction and the different modalities for treatment, including non-operative and surgical management with William W. Cross, M.D., an Associate Professor in the Department of Orthopedic Surgery at Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  Resource:   Sacroiliac Joint Clinic in Minnesota - Overview - Mayo Clinic

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Mark A. Whealy, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Headache disorders are extremely common, and patients frequently seek our help in the outpatient setting regarding management of their headaches. On occasion, they may present to the emergency department for more severe or prolonged headaches. With this podcast, we will continue our series on headaches as we discuss intractable migraine, also known as status migrainosus. We’ll also discuss other headaches commonly seen in the emergency department. How serious is status migrainosus? How should patients with these headaches be evaluated and what are the most effective management strategies? We’ll discuss these questions with Mark A. Whealy, M.D., a neurologist and headache specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.