

Lifers with Christina Farr
Christina Farr
Veteran journalist, investor, and Second Opinion Media founder Chrissy Farr talks with the CEOs and founders who've been in the trenches long enough to know that healthcare doesn't move at startup speed. These aren't the entrepreneurs chasing quick exits—they're the "lifers" who understand that building in healthcare requires endless pivots, regulatory navigation, and decade-long timelines.No hype, just honest conversations about what it really takes.Each episode explores healthcare innovation, startup strategy, medical technology and AI, health system transformation, and investment insights from operators who've navigated regulatory challenges, clinical trials, reimbursement complexities, and the unique dynamics of the healthcare industry.
Episodes
Mentioned books

Oct 9, 2024 • 48min
What digital health needs most: Evidence
In this episode of Second Opinion, Christina Farr, Ash Zenooz, and Luba Greenwood discuss the integration and evaluation of digital tools in healthcare with guest Caroline Pearson from the Peterson Health Technology Institute. They explore the challenges in demonstrating clinical effectiveness and affordability of digital health solutions, using diabetes management tools as a case example. They address the role of evidence in the healthcare system, potential biases in standard evaluation practices, and the need for improved data sharing between digital health companies and traditional healthcare providers.—SPONSOR: 👩⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit https://www.joinmidi.com/ to book your virtual visit today.—LINKS: Peterson Health Technology Institute: https://phti.org/Peterson Center on Healthcare: https://petersonhealthcare.org/ Nonlinear dynamics of multi-omics profiles during human aging: https://www.nature.com/articles/s43587-024-00692-2 New Report Finds That Digital Diabetes Management Tools Fail to Deliver Meaningful Health Benefits to Patients While Increasing Spending: https://phti.org/announcement/new-report-finds-that-digital-diabetes-management-tools-fail-to-deliver-meaningful-health-benefits-to-patients-while-increasing-spending/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/ —FOLLOW:https://www.linkedin.com/in/pearsoncaroline/ https://www.linkedin.com/in/christinafarr/https://www.linkedin.com/in/lubagreenwood/https://www.linkedin.com/in/ashzenooz/—TIMESTAMPS:(00:00) Intro(01:39) Discussion about super aging(02:54) Introducing Caroline Pearson(04:16) Challenges in digital health solutions(05:58) The role of evidence in digital health(16:41) Employer-sponsored health insurance concerns(20:05) Collaboration and data sharing in health tech(32:05) The future of health tech and patient outcomes(33:30) Conclusion and final thoughts(34:37) The debrief

Oct 2, 2024 • 46min
Where the jobs are and aren’t in digital health
In this engaging conversation, digital health expert Christina Farr, healthcare leader Ash Zenooz, and evolving trends professional Luba Greenwood join Oxeon CEO Sonia Millsom. They dive into what defines a successful CEO in healthcare, emphasizing relationship-building and candidate evaluation. The group analyzes current job market trends in health tech, shedding light on promising sectors like health AI. They also discuss the strategic role of executive chairs and share insights on mastering leadership interviews in an evolving industry.

Sep 25, 2024 • 52min
AI's role in diagnosing disease -- with Dr. Isaac Kohane of Harvard Medical School
In this episode of the Second Opinion Podcast, Christina Farr, Ash Zenooz, and Luba Greenwood engage in a candid conversation with Dr. Isaac (Zak) Kohane, a renowned AI expert and chair at Harvard Medical School's Department of Biomedical Informatics. Zak expresses his optimism about AI in healthcare, sharing personal anecdotes to illustrate how tools like ChatGPT can enhance patient care by providing detailed and understandable information, and highlights AI's potential to address healthcare system gaps by complementing human doctors. They explored regulatory issues, data privacy concerns, and the importance of patient control over their health data, while emphasizing the need for a balanced approach that prioritizes patient care and ethical guidelines.—SPONSORS: 👩⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit https://www.joinmidi.com/ to book your virtual visit today.🩺 AWELL: Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp.—LINKS: Department of Biomedical Informatics at Harvard Medical School: https://dbmi.hms.harvard.edu/ NEJM AI, a journal from the publishers of the New England Journal of Medicine: https://www.nejm.org/ The AI Revolution in Medicine: GPT-4 and Beyond: https://www.amazon.com/AI-Revolution-Medicine-GPT-4-Beyond-ebook/dp/B0BXNVM6FCAMIE: A research AI system for diagnostic medical reasoning and conversations: https://research.google/blog/amie-a-research-ai-system-for-diagnostic-medical-reasoning-and-conversations/ Medical Artificial Intelligence and Human Values: https://www.nejm.org/doi/full/10.1056/NEJMra2214183 Transformer: A Novel Neural Network Architecture for Language Understanding: https://research.google/blog/transformer-a-novel-neural-network-architecture-for-language-understanding/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/ —FOLLOW:https://www.linkedin.com/in/isaac-kohane-729b03 https://www.linkedin.com/in/christinafarr/https://www.linkedin.com/in/lubagreenwood/https://www.linkedin.com/in/ashzenooz/—TIMESTAMPS:(00:00) Intro(02:24) Skepticism in advanced technology(04:56) AI in Medicine: Personal Anecdotes(07:29) Challenges in healthcare access(08:26) The role of ai in patient empowerment(11:26) Human clinicians vs. AI(19:45) Sponsor: Awell(20:57) Privacy concerns with AI(25:13) HIPAA compliance and medical data(26:19) Bias and alignment in AI models(29:00) The role of AI in medical decision making(33:13) Challenges in AI regulation(38:21) The future of AI in healthcare(43:56) Wrap(45:05) The Debrief

Sep 18, 2024 • 31min
Scaling a taboo-breaking business with Origin's CEO Carine Carmy
In this episode of Second Opinion, Christina Farr is joined by Carine Carmy, CEO of Origin to discuss the overlooked aspects of women's healthcare, a case for a physical clinic, and funding stigmatized fields within the complex healthcare landscape. Carine shares valuable insights on scaling the business, the importance of evidence-based care, and the future of pelvic health, including the potential impact of AI and digital health.—RECOMMENDED PODCAST:🎙️This Won't LastEavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics.Apple Podcasts: https://podcasts.apple.com/us/podcast/this-wont-last-with-keith-rabois-kevin-ryan-logan/id1765665937Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSzYouTube: https://www.youtube.com/@ThisWontLastpodcast —SPONSORS: 👩⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit https://www.joinmidi.com/ to book your virtual visit today.🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp.—LINKS:Subscribe to Second Opinion Newsletter: https://secondopinion.media/ Origin: https://www.theoriginway.com/ —FOLLOW:https://www.linkedin.com/in/carinecarmy/ https://www.linkedin.com/in/christinafarr/https://www.linkedin.com/in/lubagreenwood/https://www.linkedin.com/in/ashzenooz/—TIMESTAMPS:(00:00) Intro(01:43) The origin story of Origin(03:31) Challenges in women's health(04:02) Understanding pelvic floor therapy(05:10) Pain and gaslighting in healthcare(07:39) Building a business in women's health(10:16) Navigating health plan coverage(13:51) Sponsor: Awell(15:02) Scaling and fundraising challenges(17:42) Clinic setup and expansion(25:36) The importance of evidence-based care(29:05) Wrap

Sep 11, 2024 • 42min
The problem with bad therapy — with Alex Katz, Two Chairs CEO
In this episode of Second Opinion, hosts Christina Farr, Ash Zenooz, and Luba Greenwood dive into the intricacies of the behavioral health industry with Alex Katz, CEO of Two Chairs. They discuss the misconceptions and challenges within the mental health system, the importance of finding the right therapeutic fit, and the impact of venture capital in driving both quality and accessibility in mental health services. Alex highlights the need for personalized care, the evolving perception of therapy thanks to platforms like TikTok, and the potential and limitations of AI in therapy, emphasizing the irreplaceable value of human therapists.—RECOMMENDED PODCASTS:🎙️This Won't LastEavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics.Apple Podcasts: https://podcasts.apple.com/id1765665937Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSzYouTube: https://www.youtube.com/@ThisWontLastpodcast 🎙️Turpentine VCInvestor Erik Torenberg interviews partners at the top VCs in the world to learn their approach to the art and science of building a successful venture firm.Apple: https://podcasts.apple.com/us/podcast/id1701006772Spotify: https://open.spotify.com/show/3Yb8ErLRnyoAqn4Y6NegTx—SPONSORS: 👩⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit https://www.joinmidi.com/ to book your virtual visit today.🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp.—LINKS:Subscribe to Second Opinion Newsletter: https://secondopinion.media/ Two Chairs: http://www.twochairs.com/ —FOLLOW:https://www.linkedin.com/in/alexjkatz/ https://www.linkedin.com/in/christinafarr/https://www.linkedin.com/in/lubagreenwood/https://www.linkedin.com/in/ashzenooz/—TIMESTAMPS:00:00 Intro01:14 Behavioral health industry insights02:04 Alex Katz's journey with Two Chairs05:02 Navigating the mental health landscape08:22 Business models in mental health14:04 Barriers to mental health access16:08 Sponsor: Awell19:56 Behavioral health companies and cost reduction22:00 The crisis in therapy retention23:41 Youth mental health challenges25:40 Gen Z and therapy culture29:14 The importance of hybrid care models31:31 Skepticism around ai therapists36:00 The Debrief

Sep 4, 2024 • 50min
All the things we don’t tell women with author Leslie Schrock
In this episode of Second Opinion, Leslie Schrock, author of Bumpin' and Fertility Rules, joins Christina Farr, Ash Zenooz, and Luba Greenwood to discuss women's health, men's health, and fertility. They dive into why men need to be more involved in fertility and pregnancy conversations (it's not just a women's issue!). They address the gaps in women's health research, including the lack of understanding about how drugs and diets (like intermittent fasting) affect women differently than men. Leslie emphasizes the need for more honest, comprehensive information about pregnancy and women's health. They also discuss the potential future of women's health companies and the need for a more holistic approach to addressing health concerns beyond reproductive issues.—RECOMMENDED PODCAST:🎙️ This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics.Apple Podcasts: https://podcasts.apple.com/us/podcast/id1765665937Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSzYouTube: https://www.youtube.com/@ThisWontLastpodcast—SPONSORS: 👩⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit https://www.joinmidi.com/ to book your virtual visit today.🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp.—LINKS:Subscribe to Second Opinion Newsletter: https://secondopinion.media/ Bumpin: https://www.amazon.com/Bumpin-Pregnancy-Navigating-Wonderful-Conception/dp/198213044X Fertility Rules: https://www.amazon.com/Fertility-Rules-Definitive-Female-Reproductive-ebook/dp/B0BHTLCWZ7 —FOLLOW:Leslie: https://www.linkedin.com/in/leslieschrock/ Christina: https://www.linkedin.com/in/christinafarr/Luba: https://www.linkedin.com/in/lubagreenwood/Ash: https://www.linkedin.com/in/ashzenooz/—TIMESTAMPS:(00:00) Intro(01:37) Leslie Schrock's personal journey(02:57) The reality of pregnancy(06:55) Understanding fertility and ovulation(08:47) Challenges in women's health education(13:50) Sponsor: Awell(15:00) Investing in women's health(25:54) Understanding drug metabolism in women(26:09) Men's role in women's health(26:38) The importance of inclusive pregnancy literature(28:45) Heart health: gender differences and misconceptions(30:50) Birth control and stroke risks(31:46) Challenges in women's health research(37:11) The impact of nutrition and fasting on women's health(39:19) Future of women's health companies(41:09) Suggestions on future books and research in women's health(43:55) Wrap(46:07) The debrief

Aug 28, 2024 • 44min
Selling into the employer is harder than it's ever been with Included Health's Owen Tripp
Owen Tripp, CEO of Included Health, dives into the evolving landscape of digital health and the challenges of selling directly to employers. He highlights the importance of understanding patient needs to drive innovation in healthcare models. The discussion also touches on the significance of personalized primary care, opportunities within oncology, and the complexities of marketing digital health services. Tripp emphasizes the role of proactive outreach and trust in engaging employees with health programs, aiming to improve overall wellness.

Aug 21, 2024 • 36min
Raising from VC and PE in Health Tech with Meg FitzGerald of Grey Ghost Capital
Meg FitzGerald, a nurse turned private equity investor at Grey Ghost Capital, dives deep into the healthcare investment landscape. She discusses the slowdown in private equity deals driven by high interest rates and how venture capital is merging with private equity in health tech. FitzGerald emphasizes the importance of clinical expertise in making investment decisions and shares insights on navigating the digital health market. She also provides strategies for healthcare professionals looking to break into this competitive field.

Aug 14, 2024 • 41min
Big tech's healthcare hurdles with Sumit Nagpal, CEO of Cherish
In this eye-opening episode, Christina Farr and Luba Greenwood dive deep into the challenges big tech faces in healthcare with serial entrepreneur and Cherish CEO Sumit Nagpal. Drawing from his experience founding five companies over the past 25 years and his time working with Steve Jobs at NeXT, Nagpal offers unique insights into why tech giants struggle to gain traction in the medical world. They discuss: Apple's healthcare ambitions, the untapped potential of hardware in health tech, the importance of understanding healthcare business models, and how lessons from the diagnostics industry could shape the future of digital health innovation.—SPONSORS: 👩⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit https://www.joinmidi.com/ to book your virtual visit today.🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp.—LINKS: Cherish Health: https://www.cherishhealth.com/Subscribe to Second Opinion Newsletter: https://secondopinion.media/ —FOLLOW:Sumit: https://www.linkedin.com/in/sumitknagpal/Christina https://www.linkedin.com/in/christinafarr/Luba https://www.linkedin.com/in/lubagreenwood/Ash https://www.linkedin.com/in/ashzenooz/—RECOMMENDED PODCAST: TURPENTINE VC🎙️ This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics.Apple Podcasts: https://podcasts.apple.com/us/podcast/id1765665937Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSzYouTube: https://www.youtube.com/@ThisWontLastpodcast—TIMESTAMPS:(00:00) Intro(02:04) Why big tech fails in healthcare(05:00) Has Apple succeeded in becoming a healthcare company?(08:44) Finding adjacencies(10:11) Billionaires' health concerns driving tech investments(14:19) Sponsor: Awell(15:19) Revolving door of healthcare leaders in tech(17:14) Culture clash in tech-healthcare partnerships(19:26) NVIDIA's successful approach to healthcare(20:21) Waystar IPO(24:10) Limited options for health tech companies(26:19) Diagnostics industry parallels with digital health(28:22) Aligning Incentives(31:54) "Follow the Money" approach to healthcare solutions(34:41) The Debrief

Aug 7, 2024 • 36min
Breaking down biotech with Daphne Zohar: VC dynamics, drug development, and the Biosecure Act
Daphne Zohar, Founder and CEO of Seaport Therapeutics, shares her deep insights into the biotech landscape. She discusses the complex challenges of drug development, particularly in psychiatric treatments, while shedding light on high failure rates and funding obstacles. Daphne explores the intersection of tech and biotech investment, emphasizing the regulatory hurdles and the implications of the Biosecure Act on innovation. She advocates for greater transparency in the industry and the necessity of political support to drive progress in patient care.


