Pharmacy to Dose: The Critical Care Podcast

Literature Review SeriesNovember 2023Special Guests: Arjay Mendoza, PharmD, BCPS, AAHIVPBrock Townsend, PharmD @Townsend_PharmD 04:30 – Featured Articles35:25 – Cardiology48:05 – Precision-based medicine potpourri58:50 – Infectious Diseases69:10 – PharmD Reference List: https://pharmacytodose.files.wordpress.com/2024/04/november-lrs-2023-references.pdf PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: SOAP IISpecial Guest: Jessica Casey, PharmD, BCPS, BCCP @jmc_cardspharmd Jessica Casey joins to discuss the April Trial of the Week “Comparison of Dopamine and Norepinephrine in the Treatment of Shock,” the SOAP II study, published in NEJM in 2010. We set the scene by reviewing catecholamine vasopressor receptor physiology, guideline recommendations, and pre-SOAP II research. Then we do a deep dive into the SOAP II trial of the week. Did including all forms of shock help or hurt? How does the mortality in this study compare with others? Would this have been as positive of a study in 2024? What do the guidelines recommend now? Is dopamine dead? Will anyone take norepinephrine’s throne? Jessica and I review trial fun facts, stand-out supplementary materials, and much, much more.  Reference list: https://pharmacytodose.files.wordpress.com/2024/04/soap-ii-trial-of-the-week-references.pdf PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Salia Farrokh, a clinical pharmacist specialist, discusses landmark studies on nimodipine for aneurysmal subarachnoid hemorrhage in the 1980s. Topics include study methodology evolution, dosing regimens, missed doses, and the relevance of old evidence in current practices.

Norepinephrine Position Paper and Sepsis Research PrioritiesSpecial Guests: Brittany Bissell Turpin, PharmD, PhD, FCCM, BCCCP @BissellBrittanyPatrick Wieruszewski, PharmD, BCCCP @pwieruszSeth Bauer, PharmD, FCCM, FCCP, BCCCP @SethRBauer 07:30 – Norepinephrine position paper introduction11:35 – When did we realize this and what are the implications?36:00 – Key task force take-aways51:00 – SSC Research Committee history56:00 – Submitting and ranking research questions27:00 – Top 5 clinical sepsis research priorities62:00 – Basic science priorities Reference List: https://pharmacytodose.files.wordpress.com/2024/04/norepi-position-paper-and-sepsis-research-references.pdf PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Final Four Preview and More: 2024 Critical Care Trials March Madness Bracket Sepsis/Fluids Bracketologist: Clay Small, PharmD, BCCCPCV/Pulm Bracketologist: Jolie Gallagher, PharmD, BCCCPBleeding/BG Bracketologist: Jason Hecht, PharmD, BCPS, BCCCP, FCCMNeuro/PADIS Bracketologist: Karen Berger, PharmD, FASHP, FCCM, BCPS, BCCCP 06:10 – Region recaps 32:10 – Final Four preview and predictions45:30 – Revisiting pre-tournament predictions PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf  Listener Bracket: https://pharmacytodose.com/2024/04/01/final-four-2024-critical-care-trials-march-madness-bracket-preview-and-recap/  2024 Critical Care Trials March Madness blank bracket: https://pharmacytodose.com/2024/03/17/2024-critical-care-trials-march-madness-bracket/ PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Literature Review SeriesOctober 2023Special Guests: Hailey Burns, PharmD @Hailey_rx36Caitlyn Simonson, PharmD 03:45 – Featured Articles38:15 – Neuro50:10 – EM/Tox/Trauma61:50 – Renal/Endocrine66:38 – PharmD70:10 – Sweet Emotion Reference List: https://pharmacytodose.files.wordpress.com/2024/03/october-lrs-2023-references.pdf PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Sweet 16 Preview and Recap: 2024 Critical Care Trials March Madness Bracket Preview 04:06 – First round recap13:25 – Second round recap19:05 – Sweet 16 preview PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf  2024 March Madness Bracket: https://pharmacytodose.com/2024/03/17/2024-critical-care-trials-march-madness-bracket/  PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Pharmacotherapy in the Critically Ill Pregnant Patient: Part IISpecial Guests: Allison Lankford, MDMelissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin 04:50 – Obstetric hemorrhage18:20 – Ectopic pregnancy22:30 – Hypertensive emergency28:45 – Pre-eclampsia/eclampsia35:00 – Lactation considerations39:35 – Take-home points Pharmacotherapy “Caring for two in the ICU” articles:Part I: https://pubmed.ncbi.nlm.nih.gov/36938691/Part II: https://pubmed.ncbi.nlm.nih.gov/37323102/ PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

2024 Critical Care Trials March Madness Bracket Preview: Part IICardiac/Pulmonary and Sepsis/Fluids Regions CV/Pulm Bracketologist: Jolie Gallagher, PharmD, BCCCPSepsis/Fluids Bracketologist: Clay Small, PharmD, BCCCP PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf  2024 March Madness Bracket: https://pharmacytodose.com/2024/03/17/2024-critical-care-trials-march-madness-bracket/ PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

2024 Critical Care Trials March Madness Bracket Preview: Part IBleeding/Blood Glucose and Neuro/PADIS Regions Bleeding/BG Bracketologist: Jason Hecht, PharmD, BCPS, BCCCP, FCCMNeuro/PADIS Bracketologist: Karen Berger, PharmD, FASHP, FCCM, BCPS, BCCCP @karenccrx  PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf  2024 March Madness Bracket: https://pharmacytodose.com/2024/03/17/2024-critical-care-trials-march-madness-bracket/  PharmacyToDose.Com@PharmacyToDosePharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices