Gladden Longevity Podcast -- formerly Living Beyond 120

Dr. Jeffrey Gladden sits down with Autumn Calabrese, BeachBody Super Trainer. She shares her journey in the fitness world and her difficulties with weight loss while having a healthy way of life. She also shares her struggles with anxiety and depression, talks about gut health, and the importance of knowing thyroid genetics to understand our body. Dr. Jeffrey Gladden introduces Autumn Calabrese, BeachBody Super Trainer (2:42); Autumn shares her journey into fitness and health since her younger years through her family and her passion, dancing (3:43); Changes in Autumn's life through puberty, struggling with weight and unpleasant with her body (5:06); Autumn explains how she became a fitness competitor and the change that this had in her relationship with her body (7:09); How Autumn developed her Portion Fix nutrition program (8:27); Dr. Gladden speaks about the importance of exercise, knowing your limits, and injuries of the body (10:45); Autumn shares more about her competitions and how she trained for all: periods, nutrition (11:48); Dr. Gladden speaks about healthy living and performance, and Autumn's sense of confidence about healthy life goals (13:11); Autumn shares how her body changed in her 30s, and the rise of her anxiety and depression (14:18); Depression and anxiety are related to genetic predisposition and past experiences. Autumn shares one critical moment in her life (17:25 ); Food sensitivity and the myth of healthy foods (21:48); How Autumn got away from the food that hurts her while Dr. Gladden explains depression and gut inflammation (25: 57); Autumn talks about her experience with Dr. Gladden and how she has grown to understand her body and genetic predisposition (29:04); Optimizing body composition (36:04); The things Autumn teaches: self-care, sleep, and stress management (36:33); A new program for gut health to improve nutrition (38:28); And more! To learn more about Autumn, visit https://www.autumncalabrese.com/home To begin her new program, The 4 Week Gut Protocol, visit https://www.teambeachbody.com/shop/us/b/nutrition-programs/4weekgutprotocol Follow Autumn on Instagram: @autumncalabrese Visit our website, www.gladdenlongevitypodcast.com for more information on this episode and other episodes as well. Follow us on social media! Instagram: @gladdenlongevitypodcast Twitter: @GLPodcast_ Facebook: @GladdenLongevityPodcast To learn more about Gladden Longevity and how you can become a client, visit www.gladdenlongevity.com today!

In today's episode, Dr. Gladden will be joined by the world's leading nutritional biochemist, expert on health optimization, and ingredientologist, Shawn Wells, MPH, LDN, RD, CISSN, FISSN. The two discuss energy and fatigue related to mitochondrial dysfunction, resilience, depression, and protein BDMF. We also talk about metabolic flexibility and the Ketogenic Diet. We end with Shawn's three secrets for longevity. Dr. Gladden presents today´s guest Shawn Wells, a nutritional biochemistry expert in health optimization and discusses the health issues he has been fighting and his book "The Energy Formula" (1:16); Dr. Gladden starts the conversation by introducing energy and the aging process as a topic (3:35); Shawn Wells speaks about ICES and mitochondrial dysfunction (metabolic disfunction) (4:40); The reason for fatigue: metabolic predisposition (no back to normal function) and chronic infection that damage the mitochondria from the outside (6:37); Dr. Gladden introduces metabolic flexibility to connect the ideas about Keto Diet (11:33); Dr. Gladden discusses a study about metformin and its potential impact on longevity, and mentions how metformin activates AMPK and lowers insulin resistance by increasing insulin receptors (13:27); Shawn Wells talks about the differences and benefits from metformin (14:14); Dr. Gladden continues discussing metformin with Shawn Wells, who mentions B-12 depletion with metformin (16:35); Dr. Gladden reintroduces fatigue into the discussion (16:54); Shawn Wells expands information about alpha-keto and calcium and EKG (18:12); Dr. Gladden talk about PQQ and the coenzyme COQ-10 (19:36); Shawn Wells talks about berberine and metformin and the possibility to cause mitochondrial stress, and how mitochondrial biogenesis is related (20:22); Shawn Wells explains ergothioneine, the longevity vitamin (22:05); Dr. Gladden and Shawn Wells discuss mitochondrial oxidative stress, hydrogen, and balance (24:37); Dr. Gladden talks about the concept of resilience and aging as an exponential process (25:55); Shawn Wells talks about the importance of resilience and speaks about two types of intelligence as we get older: crystallized and fluent intelligence (26:44); Shawn Wells speaks about mental resilience, the protein BDMF, and depression (30:13); Dr. Gladden and the concept of "taking action" (33:39); Shawn Wells shares his thoughts about a healthy brain, body, and energy, as well as his experience with depression, body dysmorphia, eating disorder, Epstein-Barr Virus, Chronic Fatigue Syndrome, Fibromyalgia (35:20); Dr. Gladden extends the comment of Shawn Wells on reframing (37:22); Shawn Wells gratitude mindset is a natural reframe and mentality shift (41:38); Shawn Wells mentions one compound for intense exercising (44:57); Dr. Gladden explains BCAA amino acid (46:19); Shawn Wells talks about other compounds (47:20); Dr. Gladden and Shawn Wells discuss fasting (49:22); Dr. Gladden asks Shawn Wells for final thoughts and what he thinks about optimizing NAD (50:29); Shawn Wells shares some compounds to optimize NAD and the Vitamina B3 Niacin (50:51); Shawn Wells shares his top three tips for longevity (55:04); To learn more about Shawn and his book, "The Energy Formula", visit https://shawnwells.com/ Follow Shawn on: Facebook: @Ingredientologist Instagram: @shawnwells Twitter: @Ingredientology TikTok: @Ingredientologist LinkedIn: https://www.linkedin.com/in/ingredientologist/ Visit our website, www.gladdenlongevitypodcast.com for more information on this episode and other episodes as well. Follow us on social media! Instagram: @gladdenlongevitypodcast Twitter: @GLPodcast_ Facebook: @GladdenLongevityPodcast To learn more about Gladden Longevity and how you can become a client, visit www.gladdenlongevity.com today!

In today´s episode, Dr. Jeffrey Gladden sits down with Dr. Jennifer McCauley from Inspire Physical Therapy and Wellness in Southlake, TX. The focus of this episode is to hit on the topics of the pelvic floor, pelvic floor pain and dysfunction, and Dr. McCauley's unique and holistic approach to physical therapy. We discuss: Dr. McCauley's approach to physical therapy (4:36); The idea that movement is medicine (5:51); The relation of the time of the injury and the importance of training the brain on how to perceive pain (5:24); How the body compensates in response to pain and the anticipatory pain function in the brain (6:51); Dr. McCauley's approach to reprogramming the brain's response, including mindfulness and Dynamic Neuromuscular Stabilization (DNS) (8:50); The power of mindfulness in healing the body and dealing with pain (10:09); Pelvic pain and the various conditions associated with it for men and women (14:07); Oxidative stress and damage and strategies used to control inflammation (15:47); The relationship between the core and its relationship to the pelvic floor (17:52); Dr. McCauley's integrated approach to physical therapy (21:21); Neurokinetic therapy, how it works, and Dr. McCauley's approach with it (23:17); The various methods Dr. McCauley uses for her patients to work on stabilization at home (24:07); The pelvic floor and its relationship to pain and sexual dysfunction (28:54); The typical rehabilitation time frame for Dr. McCauley's patients (32:10); Dry needling and how it is different from acupuncture (39:47); Pilates-based therapy and how Dr. McCauley integrates that into her practice (47:00); And more! To learn more about Dr. Jennifer McCauley's practice, visit: https://www.inspireptandwellness.com/ Inspire Physical Therapy is offering a 10% discount on a 5-pack pelvic floor package! Call 817-912-1420 to schedule your appointment and mention this podcast! Visit our website, www.gladdenlongevitypodcast.com for more information on this episode and other episodes as well. Follow us on social media! Instagram: @gladdenlongevitypodcast Twitter: @GLPodcast_ Facebook: @GladdenLongevityPodcast To learn more about Gladden Longevity and how you can become a client, visit www.gladdenlongevity.com today!

Dr. Gladden is joined by Dr. Chen Chen, Co-Founder & Chief Scientific Officer of Calroy Health Sciences, and Ed Hoyt, President & CEO of Calroy Health Sciences. The trio discuss: The topic of our episode as well as a recently published article on longevity, people's genetics, and their ability to repair their arteries (1:09); Dr. Chen and Ed Hoyt, their company, Calroy Health Sciences, the glycocalyx, and their product, Arterosil (3:46); The science behind the endothelial glycocalyx and the impact it has on health and longevity (7:18); What makes up the glycocalyx and the physiology behind it (11:37); The possibilities for what could go wrong with a blood vessel (14:39); The role of the glycocalyx in mitigating oxidative stress on the heart (15:57); How the glycocalyx acts as a transducer for nitric oxide release from the artery, the things that stimulate nitric oxide release, and the benefits of nitric oxide (18:51); What causes damage to the glycocalyx (20:32); Using Arterosil and other supplements and foods to regrow the glycocalyx (26:52); How a healthy glycocalyx helps with plaque prevention (36:10); COVID-19, its effects on the vascular system and the endothelial glycocalyx, and how rhaman sulfate has a benefit in decreasing the vascular complications (39:22); Whether or not there are people who should avoid rhaman sulfate (45:45); Instances in which people should increase the dosage of Arterosil (48:26); And more! Special offer from Calory Health Sciences: Get 30% off a 3 pack (3 months supply) of Arterosil with a free gift! Visit www.arterosil.com/longevity To learn more about Arterosil and Calroy Health Sciences, visit www.arterosil.com You can also contact Calroy Health Sciences for more information. Email: support@calroy.com Phone: 1-800-609-6409 Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well! Follow us on social media! Instagram: @gladdenlongevitypodcast Twitter: @GLPodcast_ Facebook: @GladdenLongevityPodcast To learn more about Gladden Longevity and how you can become a client, visit www.gladdenlongevity.com today!

On our newest episode, Dr. Gladden is joined by Dr. Ernie Navarro and Nurse Practitioner Melissa Markel from Gladden Longevity. The trio will be discussing the "Keys to Success" on how to maneuver and succeed in the space of health, wellness, and longevity! We discuss: A new study about the correlation between the risk of heart disease and drinking coffee and tea (1:39); Our topic for this episode– what it takes to succeed and the issues that people face in optimizing their longevity (3:15); How the strategies and paths you take to optimizing your longevity looks different depending on what decade of life you are in (5:39); How supplements aren't the full answer and that biological balance is essential to moving forward (6:40); How this process and lifestyle is going to potentially have you acting differently from your peers and family members (8:56); "The Symphony of Longevity" (11:40); The importance of maintaining a regular routine, and having a plan A, B, and C (13:14); The importance of sleep and some practical steps and hacks on creating a great sleep routine (15:47); Exercise plans and how it is important to find something you enjoy and get out of your comfort zone (19:17); The mindset shift of seeing exercise as an opportunity for joy (22:50); Some practical things you can do to succeed in implementing a new diet and lifestyle (25:02); Intermittent fasting, and making sure you are not causing your insulin levels to remain high by eating constantly (26:52); Why you should not eat right before bed (29:18); Supplements and ways to incorporate them into a daily routine (31:04); Powders versus capsules (35:11); The effects of stress on aging and the importance of work-life balance (39:27); And more! Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well! Follow us on social media! Instagram: @gladdenlongevitypodcast Twitter: @GLPodcast_ Facebook: @GladdenLongevityPodcast To learn more about Gladden Longevity and how you can become a client, visit www.gladdenlongevity.com today!

On this week's podcast Dr, Jeffrey Gladden is joined by Dr. Ernie Navarro from Gladden Longevity. Dr. Gladden and Dr. Navarro sit down to talk through the topics of rejuvenation and regeneration, the various technologies and strategies being used at Gladden Longevity, and the results thus far! We discuss: Peptides as a primary tool of regeneration and rejuvenation (2:15); Technologies that can accelerate the healing process and how they are examples of regeneration (2:48); Dr. Gladden's personal experience with regeneration following a mountain bike crash and the results of using peptides and BPC-157 (3:51); Other therapies used to recover from injuries including pulse shock wave therapy, called TRT, ozone injections, and activated PRP (5:16); Dr. Navarro's take on the synergistic nature of these treatments as well as the effect ozone has with these treatments (6:31); The Fast Mimicking Diet, and how it helps prep for these procedures, as well as other ways to prepare well (9:52); The role NAD plays in the healing process (13:00); The studies done to see how stem cells respond to toxic environments filled with cytokines (13:39); Regenerative technologies and their uses in several treatments, including symptoms following COVID (18:18); The importance of being proactive in the healing process (23:00); NeuX, its relation to rejuvenation and regeneration, and how it works to diagnose injuries and give direction on bringing the body back into optimal functioning (24:45); And more! Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well! Follow us on social media! Instagram: @gladdenlongevitypodcast Twitter: @GLPodcast_ Facebook: @GladdenLongevityPodcast To learn more about Gladden Longevity and how you can become a client, visit www.gladdenlongevity.com today!

Dr. Nichola Conlon is the Founder and CEO of Nuchido, where she, along with other scientists, works to discover interventions that increase healthspan and vitality. Dr. Conlon joins Dr. Gladden this week to take an in-depth look at NAD, its role in longevity and aging, and the most advanced way to boost your NAD+. We discuss: Dr. Nichola Conlon and her work in the sphere of aging and longevity (1:31); What led to Dr. Conlon being passionate about molecular biology and aging (3:41); Dr. Conlon's experience in drug development and network pharmacology (7:04); What NAD is and why it is fundamental in the human body (10:50); What boosting your NAD levels can do for epigenetic age (13:19); NAD and its role in DNA repair (14:23); The two different states of NAD, and the importance of the ratio between NAD+ and NADH (16:21); Why NAD declines with aging (18:53); What optimizing your NAD levels at a younger age can do for mitigating cellular senescence (25:09); Ways to increase your NAD at various ages (26:57); How Dr. Conlon has designed Nuchido to raise NAD levels and her research process (29:29); The benefits of taking Nuchido's TIME+ products compared to other precursors (44:23); Why getting a NAD infusion without a properly functioning salvage pathway does not produce the desired results and is not a long-term solution (47:53); Why Dr. Conlon chose to use nicotinamide as a precursor (50:14); Dr. Conlon's current ongoing study (51:55); What is Glycanage (54:54); Dr. Conlon's main takeaway (56:58); And more! To learn more about Nuchido and purchase Nuchido TIME+, visit https://nuchido.com/. To get 10% off your purchase with Nuchido use the code "GL10" at checkout! Use code "GL20" at checkout, this will apply a 20% discount to first order at Nuchido.com (new customers only) To get in contact with the team at Nuchido, email them at care@nuchido.com.

This week, Dr. Jeffrey Gladden is joined by Dr. Ernie Navarro from Gladden Longevity to have a conversation on the latest research and various preventative actions we can take in light of the Omicron variant! We discuss: Today's topic on the Omicron variant and introducing Dr. Ernie Navarro (1:09); A short recap on COVID-19, how Omicron is different, and the potential for the devolution of COVID-19 (2:02); Dr. Navarro's take on what is going on with Omicron (4:43); The potential for reinfection with Omicron as well as the potential effectiveness of the vaccine(7:56); Some tips from Dr. Navarro on how to approach personal health and prevention in light of Omicron (10:28); Different immune-boosting supplementation and what they do for the body (13:26); The importance of starting a treatment regimen as soon as possible, as well as the importance of practicing prevention rather than waiting for symptoms to start (24:52); The long-term effects and symptoms that follow COVID-19 (27:23); And more! Reach out to Gladden Longevity with any questions or to order any of the supplements we discussed! Phone: 972-310-8916 Email: info@gladdenlongevity.com List of Immune Boosting Supplements: Vitamin D, C, Zinc, Avmacol Extra (Sulforaphane), Quercetin, Arterosil, Iodine, Selenium, Melatonin, NAC, Curcumin, Garlic, Thyme, Oregano, SPMs, Sambucus, Andrographis, Echinacea, Astragalus, Viracid, and Humavir.

On this episode, Dr. Gladden is joined by the brilliant Dr. Sandra Kaufmann, founder and CEO of The Kaufmann Anti-Aging Institute, author of "The Kaufmann Protocol: Why We Age and How to Stop It", and the Chief of Pediatric Anesthesia Memorial Health Care System. We discuss: Dr. Kaufmasn's accolades and experience (1:07); Dr. Kaufmann's background in the antiaging space (4:07); What steps Dr. Kaufmann began to take to explore performance and longevity (6:35); What the seven categories of cellular aging are (7:43); Of the seven, which pathways that Dr. Kaufmann has gone after the most (9:52); Spermidine and how it protects our DNA (10:21); How the different aspects of aging all interrelate and work together (10:56); Senescent cells and Dr. Kaufmann's approach to them (11:43); Different experiences Dr. Kaufmann has personally had with various treatments and regimens for combatting senescent cells (15:45); Gladden Longevity's ability to measure various aspects of aging (17:17); Dr. Kaufmann's self-testing experience and her strategy for combatting aging that she has created thus far (18:02); What glycation is and how it works in the body (20:51); Different amino acids Dr. Kaufmann has been using to combat glycation (22:14); Dr. Kaufmann's DNA repair strategy (26:38); Dr. Kaufmann shares about waste management (29:05); Dr. Kaufmann's approach on lengthening her telomeres (35:30); What is behind telomere shortening and lengthening (36:06); What the mitochondrial transition pore is and how it plays a role in aging (40:14); Inflammation, how it plays into aging and affects longevity, and Dr. Kaufmann's strategy to combatting it (43:52); Where Dr. Kaufmann is functionally in rock climbing (48:57); Dr. Kaufmann's outlook on longevity strategies (52:22); Three things Dr. Kaufmann recommends to the audience to improve their longevity and performance (53:39); And more! Dr. Sandra Kaufmann, founder and CEO of The Kaufmann Anti-Aging Institute, author of "The Kaufmann Protocol: Why we Age and How to Stop it", and the Chief of Pediatric Anesthesia Memorial Health Care System. To learn more about The Kaufmann Protocol, visit https://kaufmannprotocol.com/ You can also follow her on Instagram: @kaufmannantiaging To get in contact with Dr. Kaufmann, you can email her at KaufmannAAI@gmail.com

For the inaugural episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden is joined by Graham Tuttle, Certified Strength and Conditioning Specialist (CSCS), to talk about the Knees Over Toes Program and how proper exercise can play into your longevity! We discuss: What the Gladden Longevity Podcast is all about (1:06); Graham Tuttle and his experience (2:41); What the Knees Over Toes Program is, and how it is actually beneficial for our bodies (3:59); The concept of the body being "anti-fragile" and what that means (7:07); How strain actually strengthens us, while luxury and ease may weaken us in the long run (8:22); Some of Ben and Graham's accomplishments in this field, including longevity and restoring capacity (11:12); Practical ways listeners could get started in restoring capacity in their movements and exercises (14:36); Graham's personal experience with knee issues and his rehab story (18:15); Bodybuilding, and some of its shortcomings (19:08); How the program has benefited Graham and the results of it (21:59); Some things Graham has the ability to do now that he could not do before starting the program (24:15); Different forms of therapy and approaches that they may incorporate with exercise and the program (26:54); Graham's personal experience with physical therapy as part of his rehabilitation and overall blending into his exercise regimen (35:03); Dr. Gladden's personal experience with ankle sprains and steps he took to rebuild and strengthen his ligaments (38:06); The role dexterity and grip strength play in longevity (40:07); The difference between loading your muscles versus loading your joints and bones, and how doing one tends to lead to injury (42:03); How you can be better at any age, not just in your 20's (46:26); And more!