Gladden Longevity Podcast -- formerly Living Beyond 120

Is it possible to achieve unlimited lifespan in the human body? What is the importance of changing your mindset about aging and dying? Join Dr. Jeffrey Gladden, Steve Reiter and Jim Strole in this episode of the Gladden Longevity Podcast. James Strole is the Executive Director of the Coalition for Radical Life Extension, which is the producer of RAADfest, the largest global event of its kind. James is also the Co-Founder and Co-Director of People Unlimited, an organization that supports people interested in unlimited lifespans. Co-author of the book Just Getting Started: Fifty Years of Living Forever, James is a visionary anti-death activist and community builder who has spoken and written on radical life extension and physical immortality for over four decades. He has dedicated his life to challenging death-oriented beliefs and practices and has coached thousands of people in living an ageless lifestyle to achieve healthier, fuller, more vibrant lives. He has appeared on numerous TV shows both domestically and abroad and has spoken to audiences on four continents. This episode discussed the potential for immortality, innate potential, immortal lineage, and upcoming super longevity protocols. Do you know how to get involved, and connect with people that are living and promoting a super longevity lifestyle?    Listen to this episode to learn about making 100 the new 30, and living young for a lifetime!  -- DISCOUNT:  Use code “gladden” for a RAADfest 10% discount on admission at checkout in raadfest.com  And/Or send that same code to People Unlimited at welcome@peopleunlimitedinc.com for a 30-day complimentary membership to attend events, online or in-person (Scottsdale, AZ)   -- Dr. Gladden talks about the show, and what it’s about and introduces Jim Strole. (1:33)  Jim and his partner have been studying immortality since 1972. They discuss the early lack of scientific knowledge on the topic but mention hearing a geneticist in 1975 who confirmed the possibility of immortality. They formed an international organization called People Forever to speak about immortality and super longevity worldwide. (02:18)  Dr. Gladden and Jim say that the fear of death motivates our extreme fear of living, but there is scientific evidence that suggests a longer and healthier lifespan is possible through various innovations. (03:48)  Immortality may not be achieved through one magic bullet but through a series of steps. (5:14)  Jim shares that we don’t only have the ability to live an unlimited lifespan but also to be maximally creative. (07:40)  Jim notes that living without fully embracing goals and being limited by time prevents human development and self-discovery. (10:42)  Jim explains that because of the old death pattern we live in, we are repeating the same old patterns. (12:45)  An international organization called People Unlimited promotes unlimited lifespans and immortality. They formed a coalition for radical life extension and organized a Woodstock-like event that drew over a thousand people, including scientists. The event has grown and will have more presenters this year. (15:05)  They discuss cross-pollination of ideas among brilliant and ambitious individuals in the field, fostering innovation and creating an environment for scientists to collaborate. They also mention a project focused on decoding aging and manipulating genetic expression for youthfulness. (19:29)  Jim talks about RAADfest, where it’s going to be, the location, and how to learn more. (21:35)  Jim considers the belief in an innate energy in our bodies that can potentially lead to unlimited lifespans but emphasizes the need for effort and change to access it. (24:02)  By freeing biology from limiting thoughts, embracing a new life force, and shifting mindset, one can profoundly impact health and productivity, leading to a longer and more fulfilling life. (27:27)  The spirit of immortality is in our bodies. (29:00)  For a RAADfest discount code and more information, visit raadfest.com. For podcast info, go to gladdenlongevitypodcast.com and find them on social media. (29:22)                 Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                             Follow us on social media!                                       Instagram: @gladdenlongevity                                       Twitter: @gladdenlongevit                                       Facebook: @GladdenLongevity                                LinkedIn: @GladdenLongevity       For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com  Call us: 972-310-8916  Or email us: info@gladdenlongevity.com      To learn more about Jim, People Unlimited and/or RAADfest, check out the following:   Coalition/RAADfest office: 480.345.6554  |  People Unlimited Inc: 480.656.6068  Email: info@rlecoalition.com  |  welcome@peopleunlimitedinc.com  Website: www.rlecoalition.com and www.raadfest.com  |  www.peopleunlimitedinc.com  Social Media: @rlecoalition (Instagram, Twitter) www.instagram.com/rlecoalition   |  www.instagram.com/peopleunlimitedinc  Coalition for Radical Life Extension (Facebook, LinkedIn):   https://www.facebook.com/rlecoalition   https://www.linkedin.com/company/coalition-for-radical-life-extension/ 

How do you get started on a brain health program? Join Dr. Jeffrey Gladden and Guy Odishaw in this episode of the Gladden Longevity Podcast. Guy Odishaw is a CTO, NFP, healthcare entrepreneur, bioelectric medicine practitioner, and founder of Bhakti Wellness Center, one of the country's largest, most diverse, integrative student health clinics at the University of Neuromodulation. Cofounder of Minnesota Bredesen Clinic - Dementia Prevention & Treatment Co-founder of CerebralFit Brain Training, a Nutraceutical, Electroceutical company. Guy’s 30 years of clinical experience specializing in treatment-resistant chronic pain, traumatic brain injury and psycho-emotional trauma informs his approach to brain health. Additionally, his 20+ years as a meditation instructor and facilitator of courses on personal growth help him understand how to support clients through the potent changes arising from Neurotherapy. Brain training not only alleviates unwanted symptoms; but also, positively changes one’s whole sense of self and relationship to the world around them. This episode discussed solutions for addressing cognitive decline and neurodegenerative conditions, bioelectric medicine for improving health and vitality, infrared light’s effect on the brain and body, and the power of entrainment to restore brain function.   Listen to this episode to learn about making100 the new 30 and living young for a lifetime! -- REFERRAL: 
 
Get your CerebralFit here: http://www.awin1.com/cread.php?awinmid=47857&awinaffid=1319375  -- Dr. Gladden talks about the show and what it’s about. (00:53)  Trained acupuncturist turns to Bioelectric Medicine. (03:49)  Guy shares how a practitioner invited him to watch her work. (5:02)  Electrical signals in the body; unexplored, limited potential. (08:54)  Physical and energetic processes, chemical and electrical levels. (11:21)  Dr. Gladden notes that Guy may be talking about intelligence at the cellular level. (13:50)  Guy speaks about gap junctions at the cellular level. (15:26)  The mouse model shows regrowth, memory not in the brain, consciousness in conversation. (18:37)  Guy details his progress over time. (21:45)  Dr. Gladden says to understand what was going on, he discovered they needed both the anatomy and physiology. (23:50)  QEG provides a detailed analysis of brain communication. (26:56)  Guy explains entrainment and what he thinks about it. (29:04)  Approach: Multisystem restoration and disease combat. (32:13) Guy mentions the use of audio-visual entrainment devices as part of their plan. (32:36)  Guy describes the glymphatic system as the detox for the brain. (34:55)  Doctors' knowledge is outdated, and the medical system is flawed. Electrical stimulation and audiovisual entrainment are explained. (38:20)  You are best n0t to use your doctor as a measure of progressive medicine. (40:08)  The mitochondria do a lot of cell signaling. (42:25)  The device is similar to a brain tap and has some important features. (45:08)  Neurostimulation can help improve brain function in dementia. (49:28)  Guy goes into detail about an MIT study. (50:25)  The autism spectrum is diverse; treatment varies. (53:05)  Dr. Gladden describes the headband that has been shown and lists what it does. (55:39)  Guy voices that wearables are great for people who are healthy. (58:13)  Dr. Gladden remarks about how fascinating the conversation has been. (1:00:37)  Dr. Gladden thanks Guy Odishaw. (1:03:37)               Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                            Follow us on social media!                                      Instagram: @gladdenlongevity                                      Twitter: @gladdenlongevit                                      Facebook: @GladdenLongevity                               LinkedIn: @GladdenLongevity     For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com  Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Guy, check out the following:   www.cerebralfit.com  IG: @cerebralfit

What are the questions your listeners should ask themselves and their doctors right now that could save their lives? Dr. Jeffrey Gladden and Joe Bhakdi discuss that in this episode of the Gladden Longevity Podcast. Jo Bhakdi is the Founder and CEO of Quantgene with the mission to extend the healthy human life span by a decade within a decade. Together with Quantgene’s team of scientists and engineers, he is dedicated to introducing cloud, AI, and precision diagnostics into the standard of care to enhance the quality and accessibility of care for everyone and protect human life. Born to scientist parents, Jo grew up with a backdrop of medical research before earning a Master’s in Economics from Tubingen University, one of Germany’s leading academic institutions. Prior to Quantgene, Jo held executive positions at BDDO and Omnicom with a focus on business model innovation and technology, then founded i2X. This investment platform provides quantitative analytics for biotechnology and technology portfolios. This episode discussed early detection – how it can save lives and how being vigilant can protect you for years to come. They also delve into how there is a care gap in American health care and what can be done to mend it. Should health care be a priority for everyone for a longer life?  Listen to this episode to learn about making 100 the new 30, and living young for a lifetime!  -- DISCOUNT:   Podcast10 (10% off your purchase at the Gladden Longevity Supplement shop (https://gladdenlongevityshop.com/)  --   Dr. Gladden talks about today’s podcast interview with Jo Bhakti on the preemptive diagnosis. (00:31)  Dr. Gladden speaks about what he has learned about heart attacks. (4:25)  Human money comes with strings attached, and caution is needed. (06:36)  Dr. Gladden says cheating is a function of stakeholders' investment and interest in the outcome. (8:40)  Interest in medicine led to studying economics, strategy, innovation, and venture capital. (11:09)  Jo gives details about his journey and starting a new company. (13:43)  Jo gives insight that risk is not a bad thing but it means volatility. (14:53)  Jo takes us through what Quantgene does. (17:10)  DNA sequencing: How it works and challenges. (20:13)  Dr. Gladden notes to find something preemptively is hard work. (23:26)  "Complex liquid biopsies combine high-tech modalities." (24:06)  "Multiple biological ages critical for longevity". (28:39)  Dr. Gladden notes that there are some hallmarks of aging. (30:48)  Jo believes that cancer mutations happen before the cancer is treated. (34:30)  Serenity offers an affordable early detection package. (37:16)  Dr. Gladden explains that most people are afraid of being diagnosed. (40:14)  Time, identity, and health. (44:12)  Many people feel like a lot of diagnosis are untreatable. (46:55)  Future systems watch over and optimize health efficiently. (48:43)  Jo emphasizes that you need to develop systems for your health.  (51:15)           Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                           Follow us on social media!                                     Instagram: @gladdenlongevity                                     Twitter: @gladdenlongevit                                     Facebook: @GladdenLongevity                              LinkedIn: @GladdenLongevity    For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com  Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Jo Bhakdi, Quantgene and Serenity, check out the following:   Website: http://www.20questions.live/   Website #2: https://www.chooseserenity.com/   Instagram: https://www.instagram.com/choose_serenity/   Personal Website: https://www.jobhakdi.com/

In this episode of the Gladden Longevity Podcast, hosts Dr. Jeffrey Gladden, Steve Reiter, and guest Chris Rhodes delve into the multi-faceted benefits of fasting, beyond metabolic factors, for overall health and longevity. Chris Rhodes is a biochemistry graduate from Loyola Marymount University and Nutritional Biochemistry PhD from UC Davis. He completed an Immunology fellowship at Stanford, where he developed a passion for longevity and anti-aging research. Initially, it seemed to be a myth, but Chris soon realized that it's a legitimate area of research with an enormous impact on disease prevention. Chris is dedicated to exploring the science behind longevity to find solutions that can solve the progression of all diseases, which is why he is Co-Founder and CEO at Mimio Health. Mimio is a nutraceutical company pioneering the world's first fasting mimetic supplement designed from clinical research to replicate the cellular health benefits of fasting without the need to fast. In this conversation, they explore fasting's profound impact on key factors such as cholesterol eFlux, inflammation, and oxidative stress while cautioning against hasty and excessive fasting practices. Rhodes provides valuable insights from his research on metabolites and their role in lifespan extension. The three also examine the positive effects of 36-hour fasting and discuss a promising CBD alternative, Pea, as a potential lifespan extender. The episode underlines the importance of consistent longevity practices and provides a comprehensive understanding of fasting as a tool for enhanced health and anti-aging.  Listen to this episode to learn about making 100 the new 30, and living young for a lifetime!   -- DISCOUNT:  Use promo code "gladden10” to get 10% off your first order of Mimio at http://mimiohealth.com/ !  -- Dr. Gladden welcomes everyone to the show. (2:27)  Exciting updates on research initiatives for the audience. (02:44)  Steve shares that he is so excited about the future of Gladden Longevity. (3:56)  Dr. Gladden speaks about how impressed he is with Chris’s thoughts and approach. (5:12)  Chris goes over his background and motivations. (6:02)  Study shows eating three meals beats fasting. (9:30)  Dr. Gladden says fasting is incredibly helpful. (11:26)  Chris points out that periods of fasting time greater than 24 hours produce better results. (13:00)  Fasting triggers cell survival and rejuvenation. (14:27)  AMPK activation triggers restorative functions, impacting longevity. (16:29)  Dr. Gladden notes that in the longevity space, what you are doing and what you are actually doing may be two completely different things. (18:46)  Chris questions the effect of some popular practices and if they are actually beneficial in the long term. (19:41)  Chris highlights the benefits of fasting. (22:24)  Chris talks about what happens in the body during different nutritional states. (25:37)  Cholesterol eFlux: a better indicator than levels. (26:02)  Dr. Gladden reminds us that PCSK9 is inherited. (29:25)  Fasting benefits: cholesterol, immunity, aging, inflammation. (32:03)  AI programs replaced graduate student labor used. (35:23)  Chris goes over the list of ingredients they identified, including spermidine. (38:05)  PEA molecule enhances mood, eases pain, and improves sports performance. (40:07)  Dr. Gladden refers to different types of PEA -the micronized PEA and the ultra-micronized PEA. (43:50)  There are different gradations of Pea in the way that it's processed, which is the normal Pea micronized Pea, and then the final form, which is ultra-micronized Pea. (45:04)  Mimio helps suppress appetite during weight loss. (47:13)  Oxytocin compliments Mimio for weight loss. (50:22)  In the healthy aging space, you have things going typically the opposite. (55:03)  Starting with fasting to enhance longevity benefits. (58:49)  Mimio helps you optimize your fasting. (1:00:35)  Dr. Gladden gives a combination that helps you stay way ahead. (1:03:40)  Mimio cycling is good for the body's homeostasis. (01:05:43)  You don’t want to be doing the same thing every day. (1:08:04)  Mimio helps mitigate stress from one meal. (01:11:37)  Use the code Gladden10 to get 10% off your first order. (1:15:27)  Dr. Gladden thanks Chris for the chat and promises to have more discussions as new things come to light. (1:16:05)           Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                          Follow us on social media!                                    Instagram: @gladdenlongevity                                    Twitter: @gladdenlongevit                                    Facebook: @GladdenLongevity                             LinkedIn: @GladdenLongevity     For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com  Call us: 972-310-8916  Or email us: info@gladdenlongevity.com   To learn more about Chris Rhodes and/or Mimio, check out the following:   Website: http://mimiohealth.com/  Instagram: @mimiohealth  Twitter: @mimiohealth  LinkedIn: @mimiohealth  Read the paper in the American Journal of Clinical Nutrition (https://www.sciencedirect.com/science/article/pii/S0002916522105265?via%3Dihub)

What must you look at to optimize your health and live younger for longer? Join Dr. Jeffrey Gladden, Steve Reiter, and Joe Cohen in this episode of the Gladden Longevity Podcast. Cohen experienced various health issues, such as inflammation, brain fog, fatigue, and digestive problems, which were poorly understood in traditional healthcare. Determined to find better solutions, he delved into learning about his DNA and tracking biomarkers to improve his health. This personalized approach enabled him to optimize his well-being to a level he never imagined. Inspired by his own success, Joe founded SelfDecode, the first direct-to-consumer DNA analyzer and precision health tool. SelfDecode offers accurate insights and health recommendations by utilizing AI-driven polygenic risk scoring. With over 100,000 people benefiting from SelfDecode, Joe aims to empower individuals to embrace precision health and unlock insights from their DNA and biomarkers for optimal well-being. This episode discussed health optimization, genetics, and data's role in well-being. He covered biological age, reversing it with genes and lab data. Joe also emphasized data's importance over traditional beliefs and genetics' role in understanding the body, longevity, atherosclerosis, and polygenic risk scoring, and he shared experiences with testosterone, lab tests, health optimization framework, and addressing food sensitivities. Is there a one size fits all health solution?  Listen to this episode to learn about making 100 the new 30, and living young for a lifetime!  -- DISCOUNT:  Use GLADDEN for 10% off any plan on your genetic testing at www.selfdecode.com  --   Dr. Gladden welcomes everyone to the podcast. (2:10)  Learning to surf on a paddle board with Dr. Gladden. (02:31)  Dr. Gladden says Joe is an accomplished individual. (3:10)  Joe highlights the importance of good mood, energy, immunity, body, sleep, and social interactions. (06:09)  Dr. Gladden asks Joe what instigated him to do genetic testing. (8:02)  Dr. Gladden wants to know when Joe started doing DNA testing. (10:20)  Joe shares that the critical missing piece of biochemistry is genetics. (13:18)  Genetic testing refines patient care options. (14:30)  Genetic testing needs high-quality sampling.  (16:32)  How do I improve my health? What should I do? (18:08)  Genetics affects how our body responds. (20:55)  The functional medicine movement is moving towards looking at individual variants and prescribing based on individual variants. (22:09)  Joe says other companies are looking at a few generic variants. (24:46)  The algorithm tested on public data predicts diagnoses. (26:04)  Joe highlights what they do differently by sharing about imputation. (28:55)  There is no 80/20 rule in science. (31:17)  Genome sequencing found carrier traits; low impact. (33:00)  Dr. Gladden commends Joe’s company for reporting details in a way that is actually usable. (35:59)  Joe explains how risk scores and recommendations work. (37:30)  Joe touches on how genetics are really good as foundational data. (39:53)  Genetics aren't destiny, and they adapt to the environment. (41:31)  Dr. Gladden says knowing your blueprint is one thing and how it has been expressed is another one. (43:19)  Joe notes that cardiovascular disease is a big killer. (45:25)  Tests superseded by reverse cholesterol transport method. (46:20)  Cardiovascular report: top recommendations, genetic variants. (49:37)  You can do a test for any marker that is of interest to you. (52:44)  TMAO is made by bacteria in the gut, and your diet determines the level. (54:00)  Get summary reports for personalized health journeys. (56:04)  Biology has to be balanced, and it’s about getting the dose and frequency right. (59:20)  Lack of security and privacy in companies. (01:02:50)  Joe reveals that they have someone that focuses on data compliance. (1:04:26)  DNA testing varies in accuracy and algorithm.  (01:07:31)  Joe emphasizes how their algorithm is better. (1:09:05)  Dr. Gladden talks about where his parents came from. (1:11:39)           Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                         Follow us on social media!                                   Instagram: @gladdenlongevity                                   Twitter: @gladdenlongevit                                   Facebook: @GladdenLongevity                            LinkedIn: @GladdenLongevity       For more information on our practice or how to become a client, visit:  www.gladdenlongevity.com    Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Joe Cohen, check out the following:  Website: https://selfdecode.com/  https://thejoecohenshow.com/  https://selfhacked.com/  Instagram: https://www.instagram.com/mrbiohacker/ (@mrbiohacker)  https://www.instagram.com/selfdecode/?hl=en (@selfdecode)  Facebook: https://www.facebook.com/selfdecode/ (@SelfDecode)  Twitter: https://twitter.com/thejoecohenshow (@thejoecohenshow)  LinkedIn: https://www.linkedin.com/company/selfdecode/ (@SelfDecode)  YouTube: https://www.youtube.com/@thejoecohenshow/about  TikTok: https://www.tiktok.com/@thejoecohenshow (@thejoecohenshow)

What roles does sleep play in the effectiveness of nutrition? Join Dr. Jeffrey Gladden, Steve Reiter and Dr. Mike Sinel in this episode of the Gladden Longevity Podcast. Dr. Mike Sinel completed his residency at Cornell University Medical Center & Memorial Sloan Kettering in New York. Dr. Sinel served as Director of Outpatient Physical Medicine at Cedars Sinai Medical Center—an Asst. Clinical Professor at the UCLA School of Medicine, he was also privileged to work closely with chiropractors and owned several medical/chiropractic integrative clinics. In addition, Dr. Sinel lectured on alternative approaches to pain and the mind-body connection at well-known institutions, including UCLA and the Esalen Institute. As a nationally recognized expert in spinal disorders and pain management, Dr. Sinel also authored several scientific articles and two well-known books on back pain, including Back Pain Remedies for Dummies. He is the owner of Physician Therapeutics. He is passionate about reducing the side effects of pharmaceuticals by bringing safe, scientifically proven, encapsulated medical foods as natural alternatives for pain, sleep, obesity, neuropathy, fatigue & cognitive decline. In this episode, they discuss the role of skin care for chronic diseases. As the podcast progresses, they talk about how food can affect chronic inflammation/issues, the mistakes people make when first addressing their need for different nutrition, and the use of medical foods to introduce and maintain optimal nutrition in people living with chronic conditions. How do we use food as medicine or wield amino acids for better health?  Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!  -- DISCOUNT:  Use code 20%off to get that same percent off your purchase at https://targetedpain.com/?sca_ref=3721228.DaACOQPa7I   --   Dr. Gladden introduces Dr. Mike Sinel, an integrative medicine doctor. (02:19)  Dr. Gladden tells Dr. Mike how he feels about doing things differently. (03:53)  Back pain mystery; need for holistic treatment. (06:02)   Dr. Mike shares how he became a yoga practitioner twenty-five years ago. (07:55)  Spirituality and wellness intersect in healing. (09:27)  Dr. Mike believes that, to some level, we are all energy. (10:23)  Dr. Mike says getting into deep yoga practice was his first thirst for spirituality. (12:03)  Holistic medicine references, integrating community resources. (14:24)   Encapsulated medical foods balance cellular nutrient demands. (16:40)  Dr. Mike thinks amino acids are the precursors to neurotransmitters. (18:56)  Safe, effective medical foods with no side effects. (21:04)  Dr. Mike says there is a risk-benefit analysis to it. (24:24)  Effective therapy for pain at a discounted price. (25:13)  The medical officer prescribes Centre AM for fatigue. (27:33)  Dr. Gladden explains that you don’t want to confuse amino acids with dietary proteins. (28:39)  Dr. Mike shares that many people don’t have the ingredient they put on their labels or products. (31:48)  Regenerative medicine, important basics, biohacking. (32:51)  Rapamycin and a-carbo improve longevity. (33:54)  Dr. Gladden explains how to deal with sugar. (34:54)  Dr. Gladden thanks Mike for being on. (37:15)  Mike thanks Steve and Dr. Gladden. (37:55)           Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                        Follow us on social media!                                  Instagram: @gladdenlongevity                                  Twitter: @gladdenlongevit                                  Facebook: @GladdenLongevity                           LinkedIn: @GladdenLongevity     For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com  Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Dr. Mike Sinel, check out the following:  Website: https://www.medicalfoods.com/  Instagram: http://www.instagram.com/drmichaelsinel_md (@drmichaelsinel_md)  Twitter: https://twitter.com/dr_sinel (@dr_sinel)  Facebook: https://www.facebook.com/profile.php?id=100083172978485 (@Michael Sinel MD)  LinkedIn: https://www.linkedin.com/in/dr-michael-sinel/ (@Dr. Michael Sinel) 

Do you know how to take care of your skin? Or the current mistake you are making? Join Dr. Jeffrey Gladden and Amitay Eshel in this episode of the Gladden Longevity Podcast. Amitay Eshel is an entrepreneur in the biohacking and beauty fields. He has held executive roles in the health, wellness, and beauty industry for over a decade and has been a business development consultant in that space. As Co-founder and CEO of Young Goose, the biohacking skincare company, and host of the Young Goose’s Biohacking Beauty podcast, Amitay has been making waves in his industry through education and innovation. Young Goose embodies his two passions, performance optimization and skin health, with products that boost the functions of natural rejuvenation processes in the skin. In this episode, they discuss skincare, longevity, and best practices for the best skin. As the podcast progresses, they talk about advances in skincare, the difference in approach with Young Goose, and how skincare plays into longevity. Next, Amitay Eshel delves into the science of senescent cells and their implications on aging. Eshel examines how these cells become a big driver of aging as we grow older and infect healthy cells, leading to an accumulation of senescent burden on our skin that drives whole-body aging. He discusses the importance of eliminating these cells from areas exposed to environmental toxins and even reveals that a serum aimed at removing these cells exists. So, what can you do immediately for your best skin?  Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!  -- DISCOUNT:  Get 10% OFF your skin performance products at https://www.younggoose.com/AGEHACKERS using the code: AGEHACKERS10  -- Steve gives an overview of the discussion with Amitay Eshel. (00:38)  Dr. Gladden introduces Amitay Eshel and shares his focus. (3:30)  Amitay shares how he started off his career. (6:00)  Amitay says that most people like to give labels to things. (7:37)  There is a physical toll of special forces training. (8:00)  Amitay speaks about navigation training as one of the more difficult trainings. (10:05)  Building resilience is the key to success. (11:31)  Amitay notes that you are not aging linearly. (13:44)  Amitay explains that the question they get the most is – ‘How fast do I see a difference?’ (15:47)  Stress ages people quickly, so best to think of resilience first. (17:04)  Dr. Gladden reveals that the antidote to aging is being youthful. (18:48)  Red light therapy is an amazing technology. (21:03)  Amitay states that one of his favorite topics is senescent cells. (23:47)  Amitay gives examples about not being able to mimic the facial expression of others because of the heavy use of Botox. (25:04)  Science has shown that people can look at you and infer your biological age. (27:43)  The way you treat yourself from the inside will affect the way your skin is. (29:30)  Dr. Gladden asks Amitay to talk about how senescence is measured. (31:12)  Amitay discloses that one can also have leaky skin. (32:56)  Steve asks how you know if your skin isn’t detoxifying well, and Amitay shares expert tips for detoxifying for clearer skin (34:37)  Amitay clarifies the use of coconut husk. (38:36)  Dr. Gladden mentions GHKCU use. (41:28)  Amitay says what we call epigenetic expression is true. (45:05)  Peptides and marine compounds are the ultimate collagen boost. (47:25)  Amitay has a system that he has developed to upregulate certain genetic expressions. (49:18)  Amitay emphasizes that the skin cannot break down resveratrol. (51:38)  Eliminating senescent cells is a key to slowing aging. (54:30)  Amitay lists areas in our body where we can find most senescent cells. (56:12)  Amitay explains that the young goose does not grow older after a certain age. (1:00:34)  Dr. Gladden thanks Amitay for being on the show. (1:03:25)             Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                       Follow us on social media!                                 Instagram: @gladdenlongevity                                 Twitter: @gladdenlongevit                                 Facebook: @GladdenLongevity                          LinkedIn: @GladdenLongevity     For more information on our practice or how to become a client, visit:  www.gladdenlongevity.com  Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Amitay Eshel and Young Goose Skincare, check out the following:  Website: https://www.younggoose.com/  Facebook: @YoungGooseSkincare https://www.facebook.com/younggooseskincare  Instagram: @young_goose_skincare https://www.instagram.com/young_goose_skYincare/  YouTube: https://www.youtube.com/@younggoose4113  LinkedIn: @AmitayEshel https://www.linkedin.com/in/amitay-eshel/

Do you know that supplementing NAD or glutathione with frequent IVs might be hurting your cell’s ability to adapt? Join Dr. Jeffrey Gladden, Steve Reiter and Dr. Seeds in this episode of the Gladden Longevity Podcast. Dr. Seeds is a board-certified orthopedic surgeon practicing medicine for over 27 years and the Founder and Medical Director of the Seeds Scientific Research & Performance Mastermind. He has been honored at the NFL Hall of Fame for his medical expertise and in treating professional athletes. He serves as Professional Medical Consultant for the NHL, MLB, NBA, and NBC’s Dancing with The Stars. Dr. Seeds is also a medical researcher and continues to write and publish in the NIH and other medical journals. He is also the author of Peptide Protocols Vol.1, the world’s first handbook about peptides written for practitioners. Today at the Seeds Scientific Research and Performance Institute, he is dedicated to bringing Cellular Medicine and the study of Epigenome to the forefront of the medical community through research, training, and improved patient outcomes. His practice is at the Olympic training facility: Spire Institute Geneva, OH, and at the Redox Medical Group, Beverly Hills, CA. This episode discusses how cellular redox is quickly going to become the health goal and how this is where disease, aging, and cancer starts, and that it is also where we can find solutions. As the podcast progresses, they talk about our cell’s main job, the balance and the imbalance of oxidation and reduction, and the benefits of achieving cellular redox. They explore various peptides and their ability to maintain homeostasis of redox, improve gut health, decrease anxiety, and aid in recovery after injury or training. Moreover, they touch on the importance of addressing gut health to tackle immune issues and offer dosage recommendations for peptides.   Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!    Dr. Gladden mentions that Seeds was the one that certified him in peptides. (1:15)  Dr. Gladden explains that we make peptides in our bodies. (2:24)  Dr. Gladden welcomes Dr. Seeds. (4:10)  Dr. Gladden explains cellular redox. (6:14)  Dr. Seeds shares that his mission was to introduce people to cellular medicines. (8:09)  Dr. Seeds speaks about making microfilaments in a cell to keep the structure of the cell symmetrical. (10:35)  Dr. Seeds shares that if you're regulating the infrastructure of a cell to keep it at its optimal, and you're keeping the signaling at its optimal, then you're reducing cellular redox issues, and you're reducing problems that create, like fibrosis. (12:40)  Dr. Gladden asks Dr. Seed about the interplay between GHKCU and BPC 157. (15:40)  Dr. Gladden discloses his observations that injuries seem to heal faster with the use of peptides. (18:03)  Dr. Gladden shares that he wakes up feeling 27 every day. (19:50)  Dr. Gladden goes over what being nominated means. (21:25)  Dr. Gladden emphasizes that people could make a case for using BPC on a daily basis. (24:13)  Dr. Seeds says T-regs cells are masters of immune tolerance. (28:00)  Dr. Seeds reveals the discovery of zonulin, which is a toxin from the cellular connection in the bowel. (32:25)  Dr. Seeds advises that people need to focus on the gut with lots of immune issues. (35:15)  Dr. Seeds discloses a peptide that helps with leaky gut. (37:36)  Dr. Seeds speaks about one of the best peptides available that can be used intranasal or subcutaneously. (41:28)  Dr. Seeds reveals that BDNF is a big player in anxiety and depression. (44:10)  Dr. Seeds advises that you must be careful with CMAX because it’s more of an activator. (47:40)  Dr. Seeds refers to how working with younger kids is a game changer. (50:25)  Dr. Seeds says there are good and bad aspects of nicotinamide. (54:25)  Dr. Seeds spells out one of the best peptides we have if you know how to use it. (57:00)  Dr. Seeds refers to an incredible peptide that only needs to be used for short periods. (59:00)  Steve announces that Dr. Seeds has a book on peptides and thanks everyone for listening. (1:00:07)           Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                      Follow us on social media!                                Instagram: @gladdenlongevity                                Twitter: @gladdenlongevit                                Facebook: @GladdenLongevity                         LinkedIn: @GladdenLongevity    For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com  Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Dr. Seeds and his work, check out the following:    https://seeds.md/  For health practitioners: ssrpinstitute.org  For health enthusiasts: redoxmedicalgroup.com  IG: @williamaseedsmd @ssrpinstitute @redoxmedicalgroup    DISCOUNT:   Podcast10 (10% off your purchase at the Gladden Longevity Supplement shop (https://gladdenlongevityshop.com/) 

Do you know the #1 killer of people in the US that kills more people than all cancers combined? Join Dr. Jeffrey Gladden, Steve Reiter, and Rhonda Rhyne in this episode of the Gladden Longevity Podcast. Rhonda Rhyne is a highly accomplished healthcare executive with a Bachelor of Pharmacy and an MBA. Most of her career has been spent in cardiovascular medicine and industry, primarily in medical devices. With experience in General Electric Medical Systems and Cardiodynamics, she became fascinated by the biomarker world, particularly non-invasive cardiac output and single biomarkers such as BNP. Rhonda then became the CEO of Prevencio, leading the company towards developing multi-analyte or multi-protein tests after seeing the potential of these combinations. In this episode, they discuss current diagnostic testing modalities, including exercise/echo/nuclear stress tests, coronary artery calcium scores, cholesterol, single protein blood tests, and genetic scores that have lower accuracy as compared to AI-driven multiprotein blood tests. As the podcast progresses, they look at how Prevencio’s HART blood tests were developed through the use of AI to select and combine multiple proteins and optionally clinical parameters in an algorithm and scoring system that has almost 90% accuracy for detecting whether you have heart disease and are at imminent risk of heart attack (HART CADhs), or one year risk of heart attack, stroke or cardiac death (HART CVE). They discuss the negative effects of alcohol on sleep and exercise routines, as well as how the enzyme alcohol dehydrogenase can contribute to aging. Rhonda shares their experience conducting cardiopulmonary exercise tests and strategies for protecting kidneys during contrast dye exposure. We dive into the importance of identifying insulin resistance and understanding genetic expression in predisposition to cardiovascular disease. Finally, we look at a new algorithm combining six parameters for a more accurate diagnosis of coronary artery disease. Do you know you can use the HART tests as a baseline to track and trend your hopeful improvement or deterioration of your heart?   Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!      Dr. Gladden welcomes everyone to the show and shares how he met Rhonda (2:15)  Rhonda shares how she got into what she presently does and her background. (3:15)  Through proteins, we see how a genetic expression is. (5:33)  Dr. Gladden highlights that high-sensitivity troponins and other proteins are being identified as potential markers for heart disease. (7:03)  Dr. Gladden observes troponin levels rise in people who exercise but not exercising may show normal ranges. (9:55)  Dr. Gladden shares how adiponectin protects arteries from oxidative stress. (12:22)  Rhonda reveals that they fed machine learning all the proteins they could get. (14:30)  Heart health comes down to a lot of things, not just one. (16:25)  Rhonda says they are in the process of collecting data and doing case studies. (18:52)  Gene expression can be modulated to achieve balance in the body's complex ecosystem using custom peptides. (21:42)  Dr. Gladden says, in his practice, one of the issues he faced was taking care of people's kidneys. (23:28)  Rhonda gives information about a test that is not commercialized yet but is just in the process. (26:56)  Steve asks about the long-term effects of what Dr. Gladden mentioned. (27:40)  Rhonda says the PAD will soon be available. (29:40)  Rhonda discloses that, in August, she will have been with the company for ten years. (31:11)  Dr. Gladden insinuates that there is a lot more to insulin levels than people realize. (33:23)  There are no side effects in getting a simple blood test. (35:26)  Rhonda talks about the accuracy of their tests compared to traditional ones. (38:02)  Rhonda thanks Steve and Dr. Gladden for the podcast. (38:50)        Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                     Follow us on social media!                               Instagram: @gladdenlongevity                               Twitter: @gladdenlongevit                               Facebook: @GladdenLongevity                        LinkedIn: @GladdenLongevity     For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com   Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Rhonda Rhyne and/or Prevencio, check out the following:  Website: https://prevenciomed.com/   Phone Number: (425) 576-1200  Linked: https://www.linkedin.com/company/prevencio-inc./ (@PrevencioInc)  Facebook:   https://www.facebook.com/Prevencioinc/ (@PrevencioInc)  Youtube:   https://www.youtube.com/channel/UCurfuy5rBjtc-ShYs_Aetpg  Twitter: https://twitter.com/RhondaRhyne    DISCOUNT:   Podcast10 (10% off your purchase at the Gladden Longevity Supplement shop (https://gladdenlongevityshop.com/)    Get the supplements mentioned in this episode!  CoQ10: https://gladdenlongevityshop.com/products/super-ubiquinol-coq10-100mg-60-softgels?_pos=1&_psq=coq&_ss=e&_v=1.0    Berberine: https://gladdenlongevityshop.com/products/berberine-60-count?_pos=1&_psq=berberine&_ss=e&_v=1.0    Bergamot: https://gladdenlongevityshop.com/products/bergamot-bpf-60ct?_pos=1&_psq=berga&_ss=e&_v=1.0    

Join Dr. Jeffrey Gladden, Steve Reiter and Joe Baffone in this episode of the Gladden Longevity Podcast. Joe is Co-Founder and CEO of Annexus Health, the leading healthcare technology company that is revolutionizing the patient access journey by delivering innovative solutions that reduce financial and administrative burdens to improve access, speed, and adherence to critical care. In his role as CEO, Joe takes a servant-leader approach and is as passionate about empowering others as he is about breaking down barriers to patient care. His work overseeing business development, strategy, and culture at Annexus Health is informed by over two decades of experience working in life sciences. Most recently, prior to co-founding Annexus Health, Joe spent seven years as a principal at onPoint Oncology, where he concepted, built, implemented, and monetized cancer access solutions. A devout Christian, Joe relies on his faith, which is central to his personal and professional decision-making. He and his wife, Jeanie, have three children, one of whom Joe has the privilege of working with at Annexus Health. This episode discusses improving the management of the patient care journey in complex disease states and the impact on longevity. As the podcast progresses, they talk about the administrative and financial challenges of the patient care journey in complex disease states as having an outsized impact on longevity. In addition, they consider the meaningful impact in complex disease states that requires provider centricity to be patient-focused and outcome-driven and that disruptive ecosystem-conscious technology approaches can be the most meaningful innovation in our healthcare system.  Listen to this episode to learn about making a 100 the new 30 and living young for a lifetime!    Dr. Gladden welcomes everyone to the podcast. (1:55)  Dr. Gladden welcomes Joe to the show. (2:37)  Dr. Gladden clarifies if Joe was the primary caregiver for his mom. (4:02)  Joe mentions how his grandfather passed away from colorectal cancer. (6:18)  Joe details some of the cool things that have happened in his career. (8:51)  Dr. Gladden points out how doctors are caught in the middle between pharmaceutical companies' high cancer drug costs and consumers who cannot pay for them. (10:48)  Joe explains repurposing data from other sources. (12:58)  Dr. Gladden talks about drugs in the pancreatic space that are so expensive but only help patients live two months longer. (15:18)  Joe shares that they have fourteen disease states but that they started with cancer. (17:01)  Dr. Gladden discusses giving away care for free and keeping a business afloat. (19:58)  Joe says that patient outreach is a critical path they are developing. (21:19)  Joe reiterates that outreach is critically important, but they still believe it funnels through the provider. (23:38)  Joe speaks about how the nonprofit world is challenging to work through to get to the decision-makers. (25:34)  Dr. Gladden asks Joe about his plan for the fourteen disease states going forward. (28:14)  Joe presents his vision of creating a technology network using its administrative enterprise platform to communicate well with other systems. (30:48)  Dr. Gladden wants to know if there is a focus on mental health to get people mental health services. (32:30)  Joe highlights one thing patients should do, and it involves owning their healthcare and understanding there are options to help them with challenges. (34:51)  Dr. Gladden gives examples of commercial insurance. (36:00)  Dr. Gladden notes that many patients are willing to control their healthcare, but what they don’t own is the backend of it. (38:19)  Dr. Gladden thanks Joe for bringing this information forward. (44:16)  Joe thanks everyone. (44:53)          Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you’d like us to talk about on the podcast too!                    Follow us on social media!                              Instagram: @gladdenlongevity                              Twitter: @gladdenlongevit                              Facebook: @GladdenLongevity                       LinkedIn: @GladdenLongevity    For more information on our practice or how to become a client, visit:   www.gladdenlongevity.com   Call us: 972-310-8916    Or email us: info@gladdenlongevity.com    To learn more about Joe Baffone’s work and/or Annexus Health, check out the following:   Facebook: @Annexus Health  Instagram: @annexushealth  Twitter: @annexushealth  LinkedIn: @JoeBaffone  Website: AnnexusHealth.com    DISCOUNT:   Podcast10 (10% off your purchase at the Gladden Longevity Supplement shop https://gladdenlongevityshop.com/)