

The Dr. Lee Warren Podcast
Dr. Lee Warren
Neurosurgeon and award-winning author Dr. W. Lee Warren, MD delivers weekly prescriptions from neuroscience, faith, and common sense on how to lead a healthier, better, happier life. You can’t change your life until you change your mind, and Dr. Warren will teach you the art of self-brain surgery™ to get it done. His latest book, Hope Is the First Dose, is available everywhere books are sold.
Episodes
Mentioned books

Jun 27, 2025 • 50min
Fix Your Brain, with Olympic Champion Steve Mesler (S12E55)
In this episode, I reunite with Steve Mesler, the 2010 U.S. Olympic gold medalist in bobsled, as he shares his journey through unexpected mental health challenges post-Olympics.
We discuss the impact of professional stagnation and health issues on his mental state, including the sobering realization of suicidal thoughts.Steve emphasizes the importance of vulnerability in dismantling the stigma around mental health and highlights the medical and therapeutic support that aided his recovery. He also shares proactive measures for maintaining mental fitness, illustrating that with the right tools and support, it's possible to thrive after adversity.
My favorite line was Steve's epiphany that led to him to seek help for his depression: "I realized that I can't fix my brain with my brain."
Click here for the transcript
Other Helpful Links:
Learn more about Steve Mesler and Classroom Champions here
Follow Steve on Instagram and Twitter for daily inspiration!
Be sure to check out my latest book, Hope Is the First Dose!
Sign up for my weekly Self-Brain Surgery Newsletter here!
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Jun 23, 2025 • 47min
Switching Things Up (S12E54)
Explore the intriguing concept of metacognition and how simply thinking about thinking can rewire your brain. Discover the 'patchbay' idea that guides your thoughts towards positive change. Delve into the mechanics of neuroplasticity and how microtubules respond to our intentions. Learn practical strategies for personal growth through 'self-brain surgery,' and uncover the ten commandments that facilitate mental transformation. This journey encourages you to take control of your mindset, promoting resilience and creativity.

Jun 20, 2025 • 36min
Moving the Target (S12E53)
Explore the art of setting the right life goals and how pursuing the wrong targets can lead to dissatisfaction. Discover the significance of aligning your aspirations with internal joy and spiritual growth. Dive into the psychology behind fulfillment, particularly for those who achieve significant milestones. Uncover how transforming your mindset can enhance your well-being and highlight the intriguing relationship between science and faith in joy. Join a journey towards self-reliance and a more meaningful approach to happiness.

Jun 16, 2025 • 37min
The Thought Biopsy (S12E52)
What if not every thought you have is true?
In this powerful episode, Dr. Lee Warren takes you into the mental operating room to practice the Thought Biopsy, a self-brain surgery procedure that helps you examine automatic thoughts before you let them dictate your emotions, choices, and behaviors.
With neuroscience, scripture, and a surgeon’s clarity, Dr. Warren guides you through a practical, life-saving mindset shift: you are not your brain, and you don’t have to believe everything you think.
Learn how to take your thoughts captive (2 Corinthians 10:5), use metacognition to stop self-malpractice, and begin rewiring your brain—on purpose—for resilience, peace, and hope.
Highlights from this episode:
The startling number of automatic thoughts you have each day—and why most of them are negative and untrue
Why trusting every thought is like a surgeon operating without a biopsy
The gift of metacognition and the “subject-object shift”
The neuroscience of automatic thoughts, hippocampal growth, and parasympathetic regulation through prayer and meditation
PLUS- A three-question litmus test for your thoughts
Scriptures Mentioned in This Episode
2 Corinthians 10:5 – Take every thought captive
Romans 12:2 – Be transformed by the renewing of your mind
Philippians 4 – Think on what is true, noble, and excellent
Acts 17:26-27 – You are here for a reason, appointed by God
📄 Free Thought Biopsy Worksheet → Subscribe at drleewarren.substack.com and we’ll send it to you
💌 Already subscribed but didn’t get it? Email us at contact@drleewarren.com🎧
Upcoming episode coming this Friday: “Shooting at the Right Target” — learn to shift your locus of control and aim your life in the right direction
If you're ready to stop letting your thoughts control your life, start with the Thought Biopsy. It’s simple, practical, and powerful. Share this episode with someone who needs to know:
🧠 You don’t have to believe everything you think.
And remember…
You can’t change your life until you change your mind. The good news is—you can start today.
More Resources and Links:
🔔 Subscribe to the Self-Brain Surgery Podcast wherever you listen
🧠 Weekly insights: drleewarren.substack.com
📱 Instagram: @drleewarren
📖 Resources, courses, and more: wleewarrenmd.com
#SelfBrainSurgery #ThoughtBiopsy #Neuroscience #MentalHealth #FaithAndScience #MindOverBrain #DrLeeWarren
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6 snips
Jun 13, 2025 • 47min
Heart Aches and Bone Breaks (S12E51)
Delve into the fascinating connection between emotional and physical pain, as both are processed similarly in the brain. Uncover the concept of 'scrubbing in' for better self-reflection and healing. Explore the neuroscience behind grief and loneliness, highlighting how valid emotional wounds can manifest as physical suffering. Discover practical strategies like journaling and community support to cope with trauma, while fostering resilience and personal growth. Embrace the journey of transforming heartaches into meaningful legacies.

Jun 8, 2025 • 1h 7min
The Origin of Life, with Dr. James Tour (S12E50)
In this episode of the Self-Brain Surgery Podcast, Dr. Lee Warren hosts Dr. James Tour, a world-renowned synthetic chemist and Christian evangelist, to discuss the intersection of faith and science.
Dr. Tour, named one of the top 50 most influential scientists globally, shares insights from his extensive research in chemistry, including advancements in brain and spinal cord injury repair, cancer treatments, and AI technology.
Beyond his scientific achievements, Dr. Tour speaks passionately about his journey from secular Judaism to Christianity, his commitment to evangelism, and the importance of not conflating scientific hypotheses with facts.
The conversation delves into the complexities of life’s origins, challenging the widely taught primordial soup model, and emphasizing that good science often harmonizes with faith. Dr. Tour also extends an open invitation to non-believers for one-on-one discussions to explore the compatibility of science and the Christian faith.
Click here for the transcript
Chapters
00:00 Introduction to Dr. James Tour
00:12 Dr. James Tour's Scientific Achievements
01:08 Dr. Tour's Journey to Christianity
01:32 The Intersection of Science and Faith
03:47 Upcoming Guests and Topics
04:18 Dr. Tour's Perspective on Origin of Life Research
08:06 Dr. Tour's Personal Testimony
13:03 Challenges and Persecutions
14:55 Dr. Tour's Scientific Contributions and Innovations
21:11 Complexities of Chemical Reactions and Life Formation
28:49 The Complexity of Assembling Life
30:44 The Miller-Urey Experiment Revisited
32:09 Challenges in Origin of Life Theories
36:54 The RNA World Hypothesis
40:12 Faith and Science: A Harmonious Relationship
50:40 The Passion for Evangelism
56:54 Final Thoughts and Invitation
Resources and Links
Dr. Tour's YouTube Channel
Dr. Tour will meet with you to discuss Jesus if you're not a believer
Dr. Tour's website (links to all his social media)
Dr. Tour on Instagram
My book, 2021 ECPA Memoir/Biography of the Year, I've Seen the End of You
Be sure to check out my latest book, Hope Is the First Dose!
Sign up for my weekly Self-Brain Surgery Newsletter here! (Get my free Thought Biopsy Worksheet when you subscribe!) Learn more about your ad choices. Visit megaphone.fm/adchoices

Jun 6, 2025 • 28min
The Devil is a Cognitive Neuroscientist (S12E49)
The host dives into the powerful interplay between neuroscience and faith, revealing how 'resistance' can block personal growth. With personal stories of hardship and recovery, listeners learn to reshape their minds to overcome life's challenges. The discussion also highlights the transformative power of thought and the harmony between scientific inquiry and spiritual understanding. Practical strategies for mental resilience are shared, inviting listeners to embrace self-brain surgery to change their lives.

Jun 2, 2025 • 60min
The Immortal Mind, with Dr. Michael Egnor (S12E48)
In this episode of the Self Brain Surgery Podcast, Dr. Lee Warren welcomes neurosurgeon Dr. Michael Egnor (written with Denyse O'Leary), who discusses his new book, The Immortal Mind: A Neurosurgeon's Case for The Existence of the Soul.
Dr. Egnor shares his journey from atheism to faith, emphasizing the distinction between the mind and the brain. They delve into scientific evidence, including functional MRI studies and split-brain research, that suggests a non-material aspect of the mind. Additionally, Dr. Egnor shares personal anecdotes and philosophical insights that support the concept of an immortal soul. The episode underscores the significance of understanding the mind-brain relationship for finding hope and purpose in life.
Click here for the transcript
Chapters
00:00 Introduction and Guest Introduction
00:16 Exploring the Mind-Brain Relationship
00:31 The Immortal Mind: Book Overview
00:42 Hope and Meaning Beyond Life's Challenges
00:59 Deep Dive into Neuroscience and the Soul
01:08 Book Giveaway Announcement
01:43 Interview Begins: Welcoming Dr. Michael Egnor
02:52 Dr. Egnor's Journey from Atheism to Faith
06:27 Challenging Materialism and Atheism
15:59 The Concept of Free Will
18:18 Defining the Soul and Its Significance
21:53 Mind, Brain, and Soul: Neurosurgical Insights
27:00 The Brain's Mysteries: Neuroscience Insights
27:31 Split Brain Surgery: Unveiling the Mind's Secrets
30:28 Twins Joined at the Brain: A Unique Connection
32:26 Persistent Vegetative State: New Discoveries
36:58 The Immortal Soul: Science and Faith
43:37 The Mind-Brain Connection: Quantum Mechanics and Philosophy
47:49 Conclusion: Changing Your Mind, Changing Your Life
Resources and Links:
Dr. Egnor's book
Dr. Egnor's writing with the Discovery Institute
Great interview between Dr. Egnor and Robery Marks
🎙️ Subscribe to The Self-Brain Surgery with Dr. Lee Warren Podcast for weekly strategies to change your brain and life.
📖 Grab my book Hope Is the First Dose. Learn more about your ad choices. Visit megaphone.fm/adchoices

May 30, 2025 • 53min
A Conversation with Rick Burgess (S12E47)
In this episode, Dr. Lee Warren welcomes Rick Burgess, New York Times bestselling author and celebrated radio host (Rick and Bubba, The Rick Burgess Show), who shares invaluable life lessons and stories from his new book, Men Don't Run in the Rain.
Rick talks about his father's enduring influence as a legendary Alabama football coach, his own journey through personal and professional highs and lows, and how faith and resilience shape his life's mission.
Click here for the transcript
Chapters
00:00 Introduction and Episode Overview
00:24 Meet Rick Burgess: A Life in Radio and Ministry
01:08 Rick's New Book: Men Don't Run In the Rain
07:26 Rick's Father's Legacy
11:18 Lessons from Rick's Father
14:45 Honoring Your Parents: A Biblical Perspective
18:56 Stories and Lessons from Rick's Life
24:55 A Father's Legacy: Fired and Honored
27:15 Battling Alzheimer's: A Coach's Resilience
30:12 The Impact of a Coach: Stories of Influence
34:25 A Son's Grief: Losing a Child
35:52 Faith and Strength: Speaking at a Funeral
40:13 Continuing the Legacy: Writing and Teaching
43:54 Final Thoughts and Resources
Resources and Links
Rick's new book, Men Don't Run in the Rain
Rick's website for The Rick Burgess Show
The Man Church Conference
Sherri Burgess' beautiful book about losing their son Bronner
My book, 2021 ECPA Memoir/Biography of the Year, I've Seen the End of You
Be sure to check out my latest book, Hope Is the First Dose!
Sign up for my weekly Self-Brain Surgery Newsletter here! (Get my free Thought Biopsy Worksheet when you subscribe!) Learn more about your ad choices. Visit megaphone.fm/adchoices

May 26, 2025 • 53min
Overcoming Sex Addiction & Rebuilding Trust: Matthew & Joanna Raabsmith (S12E46)
Overcoming Sexual Addiction & Rebuilding Trust: A Journey with Matthew & Joanna Raabsmith
In this episode of the Self-Brain Surgery podcast, Dr. Lee Warren delves into a sensitive yet critical topic—sexual addiction, infidelity, and pornography.
Featuring Matthew and Joanna Raabsmith, professional therapists specializing in sexual addiction and betrayal trauma from Memphis, TN, the conversation explores their personal story of brokenness and redemption.
The Raabsmiths share insights into how neuroplasticity and God's grace helped them rebuild their marriage and family, offering hope and actionable advice for listeners dealing with similar issues.
The episode includes a discussion on the neuroscience of addiction, the impact on relationships, and pastoral encouragement for those seeking recovery. The Raabsmiths also provide resources and practical steps for couples to reignite trust and intimacy.
Click here for the transcript!
Chapters
00:00 Introduction and Content Warning
00:39 Meet the Guests: Matthew and Joanna Raabsmith
02:17 The Raabsmiths' Journey: From Brokenness to Healing
06:16 Understanding Sexual Addiction and Betrayal Trauma
13:19 The Role of Faith in Recovery
16:46 Challenges of Pornography Addiction
21:40 Advice for Parents: Preventing and Addressing Addiction
24:25 Creating a Safe Space for Kids
25:27 Navigating Relationship Challenges
26:31 The Journey of Healing and Honesty
29:40 Building Trust and Vulnerability
31:11 Finding Purpose in Recovery
35:05 Helping Others Through Your Story
41:35 Encouragement for Those Struggling
45:39 Resources and Final Thoughts
Resources and Links:
The Raabsmith's Website
Free HONEST check in guide/challenge: raabsmithteam.com/free
The Raabsmith's book, Building True Intimacy: Creating a Connection That Stands the Test of Time
Subscribe to Self-Brain Surgery, my free weekly prescription for human flourishing, in the top 35 science publications on Substack!
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