Comedian/actors Asif Ali (@alicomedy) and Holly Burn (@hollyburncomedy) join Matt and Andy to talk about having a name that's offensive to fire victims, the new sketch special Goatface, the perils of shooting Wrecked in Fiji, the most populous cities, a lucky Mars landing spot, ants who collect the heads of their enemies, the reason behind spider silk strength, going without cell phones and why screen time disrupts sleep. This week's episode is brought to you by the new educational comedy podcast Creature Feature.

Writer/comedian Steve Brett Young (@stevebrettyoung) joins Andy and Matt to talk about his friend the Studio City Life Coach, Mary Mary quite contrary, unicorns, El Niño, salmon-tossing for plants, Robert De Niro surprises and birth canals around the world. This week's episode is brought to you by the new educational comedy podcast Creature Feature.

Writer Delaney Yeager (@delaney_yeager) joins Matt and Andy to discuss Mac and Me, Bill Gates pranks, Mars landers and Mars bars, The Seinfeld Podcast, ion drive planes, why wombats poop cubes and CRISPR-edited Chinese babies. This week's episode is brought to you by the new educational comedy podcast Creature Feature.

Comedian Myq Kaplan (@myqkaplan) returns to the show to talk about Ramin Nazer, non-flushable wipes, breathing Hitler, downwind ninjas, medical mushrooms, paradoxical drug reactions and paradoxical UK legal drug responses, big holes under Greenland, regrowing frog legs and Probably Science appearing live at SF Sketchfest.

Comedian Phil Nichol (@philnichol) joins Matt and Andy to talk about how to stand, the safety of dropping pennies, sniffer bees, devout parents, Matthew Herbert's One Pig, Podtune whale music, the first domestic dogs, the new kilogram, the new Probably Science Patreon, 3D-printed sound, Teslas vs. smoke, tuskless elephants, 99 Ice Cream, scientists on money, Phil's show Your Wrong and Everybody's Talking About Jamie.

Comedian Sarah Bennetto (@sarahbennetto) and Earwolf producer Josh Richmond (@radiotfb) join Matt and Andy to discuss 3D-printed audio jewelry that Andy definitely didn't invent, AI scares and deepfakes, Lyrebird software, Aussie synchrotrons, wine bottle particle accelerators, more Yahoo Serious talk, newly elected STEM politicians, scientists in Washington, whether Oumuamua is or isn't an alien spacecraft, whether the human life span is genetic, whether Parkinson's comes from the appendix and whether Alzheimer's comes from herpes.

Globetrotting comedian Marcus Ryan (@itsmarcusryan) joins Matt and Andy to discuss losing money internationally, optimistic condoms, Nobel Prize winners and Nobel limitations, exoplanets and moon moons, Superman films and piss-crazed goats.

Dunking vegan bassist (and Son of Schmilsson) Kiefo Nilsson (@kiefonilsson) joins Andy and Matt to discuss his upcoming live performance of Harry Nilsson's album/animated special The Point (Sunday, November 4th at Dynasty Typewriter), his collaboration on a Tim Heidecker song to raise money for HIAS, the science of microphone patterns, Kiefo's citizen science wildlife tracking (and others doing similar work), the Fermi Paradox, the Parker Solar Probe's recent milestones and the demise of the Kepler space telescope.

Comedians and co-hosts of the Jammerz podcast Wendi Starling (@wendistarling) and Megan Rice (@_meganrice_) join Matt and Andy to discuss robot microwaves, cat penises, the GATE program, Japanese asteroid rovers, mosquitos, BEES, deadliest animals, panda dating, weed making people shower and puke, sandalwood-induced hair growth and ironic purchases.

Fresh on the heels of the release of his two new Netflix specials, comedian Daniel Sloss (@Daniel_Sloss) returns to the show, joined by ProbSci regular and Twinsies co-host TJ Chambers (@tjchambersLA), to talk with Matt and Andy about Menudo, daddy taxonomy, druggy octopodes, fake early memories, Spicey and The Juice, overrated probiotics, alien conspiracy theories, and a tire reef that's poisoning the sea.