Comedian and host of the Here We Are science podcast Shane Mauss (@shanecomedy) returns to Probably Science to talk with Andy and Matt about psychedelics, his upcoming Stand-Up Science tour and being institutionalized when he nearly lost his mind. If you or a loved one are in distress, the National Suicide Prevention Lifeline's number is 1-800-273-8255.

Comedians Whitney Chitwood (@WhitneyChitwood) and Carly Ballerini (@ballca) join Matt and Andy to talk about Nazi boots, the ghost of Cole Porter, Carly’s very interesting transplant, goats and happy people, this year's Ig Nobel Prize winners, billionaires in space, a Soyuz hole, lucid dreams through meds (and the old-fashioned way), have you ever had a dream like this?, man’s egg mishap and Whitney and Carly's tour.

In addition to being a programmer and computational linguist, Ryan North (@ryanqnorth) is the writer behind Dinosaur Comics, Unbeatable Squirrel Girl, the Adventure Time comic book series, and Romeo and/or Juliet, and he joins Andy and Matt to discuss his new book How To Invent Everything, a survival guide for stranded time travelers who need to figure out where they've landed in time, and how to get civilization back to the present by inventing everything from writing and farming to buttons and birth control.

Dipak Srinivasan of the Johns Hopkins Applied Physics Laboratory makes his third Probably Science appearance to give the inside scoop on a number of current and upcoming projects and missions including, but not limited to, the Parker Solar Probe, New Horizons checking out Ultima Thule, the Space Launch System, NASA's STEREO and the Dragonfly Titan rotorcraft lander.

Creator of the hit podcast Bubble Jordan Morris (@Jordan_Morris) returns to the show to talk with Andy and Matt about bad accents, why the earliest galaxies are local, Andy's tail, the big toe evolving last, The Lottery, the recipe for mummies revealed, The Core, dolphin hybrids, Patton Oswalt and David Byrne on the Wholphin DVD and the Bermuda Triangle mystery possibly being solved.

Comedian and co-host of the Lady to Lady podcast Brandie Posey (@Brandazzle) joins Andy and Matt to talk about her aphantasia, science museums, ska daddies, lazy homo erectus, phone-induced blindness, cheating bots, There's Waldo, the Arabian sand boa, yeast radiation alarms, an aphantasia support group on Facebook, a software engineer's aphantasia experience, and Brandie's album, podcast and tour.

Thomas Patterson (@thomasdynamic), music supervisor for the new AMC series Lodge 49 (@Lodge49), joins Andy and Matt to discuss the heat, will.i.am's Future, Lodge 49 and its soundtrack, Andy's initiation into the Fraternal Order of Eagles, why baby talk is good, plastic causing a greenhouse nightmare, how sleep clears the brain of toxins, a supercomputer modeling one second of brain function, how we forgot how to swim, The Dollop episode on swimming pools, modified mosquitoes and why Earth is definitely fucked.

Comedians Sarah Albritton (@SarahAlbritton) and Josh Cheney (@joshcheeeneee) join Matt and Andy to discuss Sleeping With Sarah, narcolepsy, narcoleptic dogs, Chicago's Museum of Science and Industry, the 100 prisoners problem, massive sloth tunnels, weight on various planets, drinking Mars and trippy cicadas.

Comedian Lisa Curry (@lisa_curry) joins Matt and Andy to discuss Olympiads, the other Lisa Curry, reservoir shade balls, Bruce Lee as Kato, secret snakes, skiffs, car vibrations, prison experiment problems and old bread.

Comedian, TV host and author of the upcoming memoir My Life as a Goddess Guy Branum (@guybranum) returns to the podcast to talk with Andy and Matt about shipping stories, his knowledge of international law, legal murders in Yellowstone, how dingos changed shrubs, shark pathogens, Nanaimo bars, dogs in fMRIs, Matt in an fMRI, 19th Century female mathematicians, senior wranglers and British TV shows you should be watching on YouTube.