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Paul Saladino MD podcast

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Aug 28, 2020 • 20min

67. Linoleic Acid Makes You Fat and Dead Faster! Bonus mini-podcast!

Dive into the controversial dangers of linoleic acid and its association with chronic diseases. Discover groundbreaking studies that challenge common beliefs about polyunsaturated fats and weight gain. The discussion reveals how dietary choices might impact health and longevity. Listeners are encouraged to engage with the evidence and share their thoughts. Plus, learn about a new venture dedicated to holistic health through nose-to-tail nutrition.
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Aug 24, 2020 • 1h 36min

66. Do you need plant fiber for a healthy gut? With Lucy Mailing, PhD

Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!    Lucy’s Bio: Lucy Mailing, PhD received her Bachelor’s in Biology from Kalamazoo College and her PhD in Nutritional Sciences from the University of Illinois, where her dissertation research focused on the effects of diet and exercise on the gut microbiome in states of health and disease. Lucy has authored several peer-reviewed journal articles related to the microbiome and health and was named an Emerging Leader in Nutritional Sciences by the American Society for Nutrition in 2017. Lucy has also served as staff research associate for the Kresser Institute for Functional and Evolutionary Medicine since 2015. Lucy is the founder and sole author of NextGen Medicine, a site dedicated to evidence-based articles about the microbiome, gut and skin health, and nutrition. She is regularly invited to speak on gut health around the country and has been recognized as one of the most trusted experts in the integrative health space. Lucy plans to continue her academic training and begin a postdoc in 2020 after a gap year dedicated to NextGen Medicine.   Time Stamps:   0:12:07  Podcast starts   0:12:41  Lucy Mailing's story   0:14:13  How exercise affects the microbiome   0:15:34  Lucy breaks down the microbiome   0:25:15  Mapping your biodiversity   0:28:56  Alpha diversity vs Beta diversity   0:31:08  Medication's effect on biodiversity   0:32:38  Seasonal diets improve biodiversity   0:37:21. Fiber! Do we need it?   0:43:53  Diet rapidly and reproducibly alters the human gut microbiome   0:46:02  How Lucy healed her eczema   0:50:01  Selecting the least toxic plant foods   0:52:19
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Aug 18, 2020 • 1h 25min

65. How to heal your broken gut. Part 2 with Dr. Michael Ruscio

Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!    Time Stamps:   0:12:03 Michael Ruscio's Background 0:14:38 Divergence from dogmatism 0:19:55 Start with the gut 0:24:28 Food reactivity latency 0:26:28 Healing the gut: the algorithmic approach 0:30:11 Stopping or reducing dietary fiber intake reduces constipation and its associated symptoms https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435786/ 0:30:14 Elimination protocols 0:33:31 The healing power of fiber-free diets 0:44:05 How to feed your microbiota 0:46:59 Diet rapidly and reproducibly alters the human gut microbiome https://www.nature.com/articles/nature12820 0:47:41 Non-fiber solutions for the microbiome 0:52:35 Targeting long-term gut health through a 360 approach 0:56:22 Is the Carnivore diet sustainable for long-term adherence? 0:58:33 The spectrum of plant food toxicity 1:02:19 Leveraging the power of probiotics 1:19:12 Michael Ruscio's radical body sliding Heart & Soil: www.heartandsoilsupplements.com  @heartandsoilsupplements on Instagram   Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak
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Aug 14, 2020 • 28min

64. What really causes metabolic dysfunction? Carbs, PUFA, or aliens?

Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!  Heart & Soil: www.heartandsoilsupplements.com
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Aug 10, 2020 • 1h 34min

63. What does a carnivore diet do to the gut microbiome? Part 1 with Vincent Pedre, MD

Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!  Dr. Vincent M. Pedre, Medical Director of Pedre Integrative Health and President of Dr. Pedre Wellness, is a Board-Certified Internist in private practice in New York City since 2004. His philosophy and practices are a blend of both Western and Eastern medical traditions. He is a Clinical Instructor in Medicine at the Mount Sinai School of Medicine, as well as certified in yoga and Medical Acupuncture. Time Stamps:   0:10:46 Dr. Vincent Pedre’s background  0:13:17 The vastness of our microbiomes  0:18:31The effect of GMOs on the microbiome of the soil 0:23:15 Reversing climate change through healing the soil 0:28:41 Healing the microbiome through reconnecting with nature.  0:33:41 Saving the planet through creating ecosystems  0:34:32 Observations of the gut microbiome of the Hadza 0:39:24 Fiber does not increase microbiome diversity  0:40:44 Diet rapidly and reproducibly alters the human gut microbiome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957428/ 0:43:35 Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets https://academic.oup.com/ajcn/article/71/3/682/4729121 0:45:23 The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy https://www.nature.com/articles/s41522-018-0073-2?fbclid=IwAR1q7BKu4IN1-9g1E7PGBpwfvzVPu7Xe2g4omFEMR7B8HfBMKrd2kIHMCVw 0:45:50 Reduced
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Aug 3, 2020 • 2h 17min

62. The Carnivore Code AMA (Ask Me Anything) from Ben Greenfield Episode!

The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!    Heart & Soil is also now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com  In this AMA episode I answer questions from Ben Greenfield about my book, The Carnivore Code. It’s a deep dive into much of the science of an animal-based way eating. Prepare to learn a ton! Time Stamps:   8:03 Carnivore diet background, framework   18:25 Is there a magic ratio of fat to protein we should aim for? What is rabbit starvation?   25:53 A Review of Issues of Dietary Protein Intake in Humans https://pdfs.semanticscholar.org/4f00/4c6ff9159de2753b060df2ea1aab936db9ec.pdf   33:01. Is the decline in height and health fully attributable to plant agriculture or could it be due to industrialization?   38:43 Why do present day hunter-gatherers have no access to wild game?   42:54 How do we know that our high stomach acidity was driven by the consumption of animals?    45:09 The Evolution of Stomach Acidity and Its Relevance to the Human Microbiome https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134116   50:51 How do herbivores detoxify plant toxins?   56:34 Coevolution of poisonous plants and large herbivores on rangelands  https://journals.uair.arizona.edu/index.php/jrm/article/view/6858/6468   1:02:09 What are the studies of isothiocyanates in humans?   1:04:39  Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892312/   1:07:03  Why molecular hormesis is bad news
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Jul 30, 2020 • 1h 16min

61. Bonus episode: How to live like your ancestors in 2020, with Dr. Anthony Gustin.

Heart & Soil is now LIVE! I couldn't be more excited to share the message of nose to tail nutrition and help more people include organs in their diet. Check us out at www.heartandsoilsupplements.com!    The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Founder and CEO of Perfect Keto & Equip Foods, host of The Natural State Podcast, author of the best-selling Keto Answers. Former sports rehab clinician turned entrepreneur, trained in functional medicine and ordered labs and set treatment plans for hundreds of patients.   Time Stamps:   3:52  Being in touch with your environment bolsters human health 9:29 Why regenerative agriculture is the only way forward 16:00 On a mission to get people eating real food 17:00 Using business to force [positive] change upon the system 18:50 The importance of respecting complex systems 20:35 Chronic disease is a genetic and environmental mismatch  21:23 Returning animals to their natural environment 23:34 Lab-grown meat, and other carbon giants 28:00 Nature’s carbon cycle unnatural carbon introduction 31:31 Seasonality and diversity diminishes toxic load 40:00 Genetic adaptation takes thousands of generations 48:10 The value of learning the survivalist lifestyle 55:13 The best use of social media 1:00:20 How Anthony Gustin stays centered 1:04:30 Where to find Anthony Gustin   Heart & Soil: www.heartandsoilsupplements.com    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!
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Jul 27, 2020 • 2h 40min

60. Part 2: How not to die of chronic disease or COVID (aka how to avoid insulin resistance), with Tommy Wood, MD/PhD

The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Tommy Wood MD, PhD is an elite-level professional nerd who has coached world class athletes in a dozen sports.  He has an undergraduate degree in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in physiology and neuroscience from the University of Oslo. Tommy is a Research Assistant Professor at the University of Washington, a Research Scientist at the Institute for Human and Machine cognition, and is on the scientific advisory board of Hintsa Performance. He is also CSO (Chief Snake Officer) at the Costa Rican Center for Bro Research. Tommy lives in Seattle with his wife Elizabeth and their two goofy boxers. In his spare time he can usually be found cooking, reading, or lifting something heavy.   Time Stamps:   10:15 Tommy on Coronavirus. 13:00 Why it's okay to be wrong as a scientist. 15:00 Where are we now with Coronavirus? (12:24) (14:20-14:59)   22:17 Boris Johnson Moves To Ban Junk Food Discount Deals To Fight Obesity https://www.independent.co.uk/news/uk/politics/boris-johnson-junk-food-ban-buy-one-get-one-free-obesity-coronavirus-a9611766.html   24:45. Tommy’s article on metabolic health and pandemics.Metabolic health and lifestyle medicine should be a cornerstone of future pandemic preparedness Metabolic health and lifestyle medicine should be a cornerstone of future pandemic preparedness https://onlinelibrary.wiley.com/doi/full/10.1002/lim2.2   27:45  COVID-19 severity is predicted by earlier evidence of accelerated aging https://www.medrxiv.org/content/10.1101/2020.07.10.20147777v1   37:10 Is there an ideologically ‘’perfect’’ diet.   40:25 How does metabolic health affect our immune system? (38:44)   FIGURE 41:47  An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-019-2994-z   42:55 The NLRP3 inflamm
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Jul 20, 2020 • 1h 26min

59. How Not to Die of Chronic Disease (aka how to avoid insulin resistance), Part 1 of 2 with Tommy Wood, MD/PhD

The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Tommy Wood MD, PhD is an elite-level professional nerd who has coached world class athletes in a dozen sports.  He has an undergraduate degree in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in physiology and neuroscience from the University of Oslo. Tommy is a Research Assistant Professor at the University of Washington, a Research Scientist at the Institute for Human and Machine cognition, and is on the scientific advisory board of Hintsa Performance. He is also CSO (Chief Snake Officer) at the Costa Rican Center for Bro Research. Tommy lives in Seattle with his wife Elizabeth and their two goofy boxers. In his spare time he can usually be found cooking, reading, or lifting something heavy.   Time Stamps: 8:07 Start of Podcast 8:52 The mechanism of caffeine/other compounds found in coffee/tea/chocolate in the human body. 11:27 Paul’s thoughts on coffee.  15:42 Tommy’s thoughts on coffee. 21:37 Human detoxification of plant toxins.  24:22 Regional differences in genetics. 26:00 Benefits of  Elimination diet. 27:37 Tommy’s issues with low carb diets. 29:52 Is insulin anabolic?  36:07 Protein requirements  37:17 Physiologic insulin resistance.  51:47 What Causes insulin resistance?  58:12 Digestion of processed fat and carbohydrate  59:47 What is the fastest way to fix insulin resistance? 1:01:47 How the processing of food changes your physiology.  1:04:22 Insulin resistance in asian populations. 1:06:32 The bagel study. 1:08:37 Low-carb-high fat vs. low fat-high carb.  1:12:07 Electrolyte balance on low carb diet.  1:17:47 Where to find Tommy online? 1:19:57 The most radical thing Tommy has done recently. References: 
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Jul 14, 2020 • 2h 18min

58. Is a carnivore diet the real paleo diet? With Loren Cordain, PhD

The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Dr. Cordain is a Professor in the Department of Health and Exercise Science at Colorado State University in Fort Collins, Colorado. His research emphasis over the past 15 years has focused upon the evolutionary and anthropological basis for diet, health and well being in modern humans.Currently, Dr. Cordain's research team is exploring the connection between dietary elements that increase intestinal permeability (primarily saponins and lectins) and autoimmune disease, particularly multiple sclerosis. He has lectured extensively on the "Paleolithic Nutrition" concept world wide, and has written three popular books (The Paleo Diet, John Wiley & Sons; The Paleo Diet for Athletes, Rodale Press; The Dietary Cure for Acne) summarizing his research findings. Time Stamps:    10:16 Start of the podcast. 18:46 Paul’s nutrition journey  19:26 Do plant foods trigger inflammation? 24:16 Plants don't want to be eaten. 29:51 WGA  32:07 Lectins. 35:56 Lectins and autoimmunity  37:26 Genetic susceptibility to plant toxins.  43:01 Nuts and Seeds. 46:06 Diet of hunter gatherers.  1:00:16 Did our Paleolithic ancestors  live short lives? 1:02:22 Fructose consumption.  1:13:06 Thoughts on a carnivore diet. 1:23:16 Is there risk of nutrient deficiencies on a Carnivore Diet?  1:29:46 Sodium to Potassium ratio. 1:40:16 Do animals seek out salt? 1:51:06 Trevor’s fasting insulin levels.  1:56:16 Are there carnivore diet studies in the medical literature? 1:58:26 Are there nutrient deficiencies on a carnivore diet? (continued)  2:01:06 Other plant toxins.  2:03:30 Optimizing a carnivore diet. 2:11:16 Where to find Dr.Cordain, Mark, and \trevor’s work online. 2:12:06 The most radical thing they have done recently. References: https://onlinelibrary.wiley.com/doi/abs/10.1002/evan.20266 https://pubmed.ncbi.nlm.nih.gov/23493539/#:~:text=Indeed%2C%20the%20only%20distinction%20is,%22alcohol%20without%20the%20buzz.%22 http

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