Dr. Will Cole, leading functional-medicine expert, consults people around the world via webcam and locally in Pittsburgh. He specializes in clinically investigating underlying factors of chronic disease and customizing health programs for thyroid issues, autoimmune conditions, hormonal dysfunctions, digestive disorders, and brain problems. Time stamps:  0:11:35 - Podcast begins 0:12:30 - What is "intuitive eating?" 0:16:05 - Fasting is a byproduct of metabolic flexibility 0:17:55 - Fasting is built into who we are genetically 0:20:35 - The Hadza had long periods during the day without food 0:22:15 - Islamic fasting leads to an increased abundance of Akkermansi muciniphila and bacteroides fragilis group: a preliminary study on intermittent fasting 0:24:20 - Most people think they need to put more into their gut in order to heal 0:28:05 - The world is begging for a "pause" 0:29:45 - The effects of daily fasting hours on shaping gut microbiota in mice 0:30:00 - Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice 0:31:15 - Features of a successful therapeutic fast of 382 days' duration 0:32:00 - Betahydroxybutarate is a signaling molucule that helps lower inflammation 0:34:40 - There should be a balance when we fast, because and we can go too far with anything 0:39:30 - What serves you now might not serve you in the future 0:40:45 - What is "clean carb cycling" and how we can implement it 0:41:50 - What are the best carbs to incorprate in our diets? 0:44:20 - What are your thoughts on fructose? 0:46:15 - All sugar is not created equal 0:47:34 - Effects of Intermittent Fasting on Health, Aging, and Disease 0:50:35 - DNA repair with intermittent fasting 0:52:05 - Macro and eating-window variability is a great idea for humans 0:55:00 - Is there evidence that fasting helps with visceral fat reduction? 0:55:50 - Probability of an Obese Person Attaining Normal Body Weigh: Cohor Study Using Electronic Health Records 0:59:35 - Our body is more of a chemistry lab, rather than a calculator 1:04:10 - What are some things we should look out for when we begin our intermittent fasting journey? Sponsors: Heart & Soil: www.heartandsoil.co White Oak Pastures: Whiteoakpastures.com, use CarnivoreMD for 10% off your first order Belcampo: Belcampo.com, use CarnivoreMD for 10% of your first order Helix Mattress: www.Helix Sleep.com/carnivore md for $200 off Joovv: www.joovv.com/paul

Do you drink San Pellegrino? Gerolsteiner? Tap water? Do you know what’s in your water?  You need to listen to this podcast!  This was a fun rabbit hole to go down after one of my clients brought the possibility of Uranium in mineral waters to my attention.  Guess what?  San P, and Gerolsteiner have a significant amount of this element= no bueno. But the story gets even more complex when we try to find water that doesn’t have a ton of toxins, yet retains the beneficial components of mineral water (minerals like silica, which may actually be at the root of longevity benefits observed in the Blue Zones by preventing aluminum toxicity)... Check out this video to get my take on how to find the best water source possible and get one step closer to #RadicalHealth.  Welcome to #theremembering. 

Joel Fuhrman, M.D. is a board-certified family physician, seven-time New York Times best-selling author and internationally recognized expert on nutrition and natural healing. He specializes in preventing and reversing disease through nutritional methods. Dr. Fuhrman is the President of the Nutritional Research Foundation and on the faculty of Northern Arizona University, Health Sciences division.  Time stamps:  0:10:39 Podcast begins 0:11:54 Dr. Joel Fuhrman's story 0:17:39 Question for Dr. Joel Fuhrman: what do you believe causes chronic disease in humans? 0:24:19 Why I have a problem with epidemiological studies 0:28:59 Question for Dr. Joel Fuhrman: can you present an interventional study that shows an increased consumption of meat in the human diet resulted in negative outcomes? 0:31:29 Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans 0:33:39 Dr. Joel Fuhrman's stance on epidemiological studies 0:39:54 Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies 0:40:39 Possible protective effect of milk, meat, and fish for cerebrovascular disease mortality in Japan 0:41:29 Beef tallow increases apoptosis and decreases aberrant crypt foci formation relative to soybean oil in rat colon 0:42:59 Effects of plant and animal high protein diets on immune-inflammatory biomarkers: a 6-week intervention trial 0:44:34 Isocaloric diets high in animal or plant protein reduce liver fat and inflammation in individuals with type 2 diabetes 0:46:09 Dr. Joel Fuhrman's response: The effect of high salt consumption in Asian populations and how this affects the results in Asian studies 0:54:19 Dr. Joel Fuhrman: Keto diets are okay short term, but dangerous long term 0:55:44 Dr. Joel Fuhrman: "A 15-year study shows those who eat more meat have increased risk of cancer and death" source of this study was not presented 0:57:44 My response: there are no interventional studies that show meat in replace of plant proteins show a decrease in health outcomes in humans 1:00:29 Health promoting phytonutrients are higher in grass-fed meat and milk 1:04:39 Comparative fracture risk in vegetarians and nonvegetarians in EPIC-Oxford study 1:05:04 Partial replacement of animal proteins with plant proteins for 12 weeks accelerates bone turnover amount in healthy adults

Acne, eczema, psoriasis, vitiligo, all have their roots in inflammation and inappropriate immune system activation, but they are rarely discussed in the context of food… And yet the foods you eat are very likely to be triggering your skin issues!  In this Controversial Thoughts video, I begin to look at just a bit of the research regarding this and discuss a few very interesting studies in dogs looking at standard diet (much the like the standard American diet) vs a species-appropriate diet… Guess what? When dogs are fed a diet that’s what they are actually supposed to be eating, their skin conditions, inflammation markers, and genetic markers get much better! Imagine that…🤯 You mean feeding animals (or humans) garbage food could cause chronic illness, and returning them to a truly appropriate diet could correct this? 😜 Yup! I believe strongly that the same is true for humans, and have seen this countless times in patients, and from those in the #AnimalBased community.  What if you don’t need those super expensive rinses and skincare products… What if you just need to return to eating a “species-appropriate diet”, aka an #Animalbased diet and your skin issues will improve?  I’m betting they will!  #Radicalhealth is your birthright! This is what #TheRemembering is all about.

20 years ago, Dr. Gundry decided to prevent health issues. He retired as a cardiologist to teach patients how to eat, guiding them on how to get ahead of the problem, not fixing it after the fact. He shifted towards a more proactive approach to health through food and diet changes. Dr. Gundry has successfully treated tens of thousands of patients suffering from autoimmune disorders, diabetes, leaky gut syndrome, heart disease, and neurodegenerative diseases with a protocol that detoxes the cells, repairs the gut, and nourishes the body. He is also host of The Dr. Gundry Podcast.    Time Stamps: 0:10:19 - Podcast Begins 0:11:26 - Plants don't want to be eaten 0:16:59 - How does Dr. Steven Gundry's research on the Hadza compare to my experience? 0:21:39 - Do the Hadza eat 150+ grams of fiber per day? 0:25:04 - The Hadza consume a significant amount of calories from fructose 0:27:49 - Was meat consumption the reason humans grew such big brains? 0:33:24 - The different ways we generate excess hydrogen sulfide https://cpncampus.com/biblioteca/files/original/68df10b582353aff269c5c5ad221f8d8.pdf 0:37:15 - Effect of feeding a high fat diet on hydrogen sulfide metabolism in the mouse https://www.sciencedirect.com/science/article/abs/pii/S1089860314000226?via%3Dihub 0:39:19 - Different ways humans can generate butyric acid 0:40:49 - Not eating fiber is an option for those who can't tolerate it 0:45:26 - Will you become constipated on a keto or carnivore diet? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435786/ 0:49:59 - What happens in our bodies when we eat fructose? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533803/ 0:55:09 - Is fructose a scare for metabolicly healthy individuals? https://www.researchgate.net/publication/318344371_Efficacy_of_nutritional_interventions_to_lower_circulating_ceramides_in_young_adults_FRUVEDomic_pilot_study 1:01:44 - How do we really become insulin resistant? https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(17)30130-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1043276017301303%3Fshowall%3Dtrue 1:04:04 - Closing thoughts with Dr. Steven Gundry 1:06:14 - Pistachios have melatonin.. but they also have lectins https://www.academia.edu/20821261/Proteomic_and_immunological_characterization_of_a_new_food_allergen_from_hazelnut_Corylus_avellana_ 1:07:39 - Interesting article on Ramadan fasting https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924600/ 1:08:19 - Intermittent fasting is probably beneficial for humans https://www.nature.com/articles/s41467-020-14676-4 1:09:19 - Article: The Role of Ceramides in Insulin Resistance https://www.frontiersin.org/articles/10.3389/fendo.2019.00577/full 1:10:19 - Closing thoughts on today's podcast Sponsors: Heart & Soil: www.heartandsoil.co Cinder: cindergrill.com/pages/carnivoremd for $50 off your order Let’s Get Checked: trylgc.com/paul for 20% off your order Thanks to Let's Get Checked for sponsoring this episode.  White Oak Pastures: Whiteoakpastures.com, use CarnivoreMD for 10% off your first order Belcampo: Belcampo.com, use CarnivoreMD for 10% of your first order

I said COVID twice in the title, and vaccine once. I’m pretty sure this video will get censored!    Vaccine thoughts: Apparent benefits but many have side effects with the second dose.    I hope it’s safe for the sake of my parents...   I won’t get it because I’ve already had COVID, it was mild, and I am metabolically healthy…   Here’s hoping there’s not a vaccine mandate. I think that’s a bad idea…   Long COVID: Looks like dysautonomia, could there be an underlying immune component? I think so…    Autoimmune illnesses often respond to dietary changes like removing the most triggering foods… #theremembering

You live in a zoo… Don’t believe me? Look around you… Synthetic food, separation from nature-> chronic disease rates skyrocketing, rates of obesity, depression and general unhappiness rising rapidly… The same things happen to wild animals when they are placed into zoos!  In this week’s podcast (Fundamental Health, available on Apple Podcasts, YouTube) @dranthonygustin and I dive back into our Africa adventures with some of the last hunter-gatherers left on the planet, the Hadza. This is part 2 of this series, check out part 1 from two weeks ago… In this episode we also answer your questions about the Hadza and fill in all the gaps from our first episode about our adventures with them. #theremembering Time stamps: 0:10:49 Podcast Begins 0:12:39 Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes https://www.nature.com/articles/s41590-021-00867-8#:~:text=In%20a%20cohort%20of%20323,metabolites%20accounting%20for%20these%20differences. 0:13:56 Misinformation in modern papers on the Hadza | Cancel culture in the scientific community 0:26:49 Eat what is easily edible in nature 0:29:46 And now a word from Big Honey 0:31:07 Natural Honey Lowers Plasma Glucose, C-Reactive Protein, Homocysteine, and Blood Lipids in Healthy, Diabetic, and Hyperlipidemic Subjects: Comparison with Dextrose and Sucrose https://www.liebertpub.com/doi/abs/10.1089/109662004322984789 0:40:25 To be wild is to be healthy | How to rewild 0:47:32 What do the Hadza do to be happy? 0:49:43 Happiness is humanity's default 0:53:53 How did the Hadza sleep? 0:58:03 Surfing in Costa Rica 1:01:24 The remarkable patience of the Hadza 1:00:53 Do the Hadza operate in hierarchy? 1:13:13 An interesting theory on eating local, seasonal food 1:18:05 Prey Size Decline as a Unifying Ecological Selecting Agent in Pleistocene Human Evolution https://www.mdpi.com/2571-550X/4/1/7/htm 1:19:19 The evolution of the human trophic level during the Pleistocene https://onlinelibrary.wiley.com/doi/10.1002/ajpa.24247 1:19:44 Too smart for our own good | Refining away our last source of real food 1:23:54 The hygiene of the Hadza 1:26:35 How to find your true love 1:30:47 Marriage and sexuality 1:37:49 Gender roles of the Hadza 1:39:47 Some thoughts on human customs

Oooo guys! This is a good one, and it’s going to ruffle some keto-feathers…   There is a tendency within nutritional circles to fall prey to reductionist thinking…   We know sugar is bad, right? Therefore any foods (not matter how evolutionarily consistent) that contain sucrose, or the evil-fructose are bad for you, too, right?   Not so fast seabass!    These apparent evolutionary inconsistencies have always puzzled me and caused me to wonder about how foods like honey or fruit might be different than pure sucrose, or if your body’s response to fructose might be dependent on the food it’s in…   Imagine that! Food might actually be more complex than just calories, and macronutrients…   It might actually have different effects on your body when it’s a “whole” food like honey, or even sea salt vs refined sodium chloride…   Check out this week’s edition of Controversial Thoughts to journey with me down all of these rabbit holes…   I bet you will be surprised at what we find! Welcome to #theremembering 

This is the third AMA podcast I’ve done and it was a fun one!  Time stamps with questions I answer in this one are below. If you have questions for future AMAs send them to radicalhealth@heartandsoil.co!    Time Stamps:  0:11:08 Ask Me Anything! 0:13:21 What are the best labs to get done? 0:21:49 How do we most effectively share the animal-based lifestyle with friends and family? 0:24:34 Is a plant-based diet more financially sustainable than an animal-based diet? 0:27:03 Zach Bush, Tetrahydrate, and eating dirt 0:32:49 The Scoop on Candida 0:39:15 Natural Honey Lowers Plasma Glucose, C-Reactive Protein, Homocysteine, and Blood Lipids in Healthy, Diabetic, and Hyperlipidemic Subjects: Comparison with Dextrose and Sucrose https://www.liebertpub.com/doi/10.1089/109662004322984789?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed& 0:39:15 Why honey is different than other carbs 0:42:35 Paleoanthropology and the origins of modern disease Https://www.youtube.com/watch?v=3fewDdSUSwg 0:42:35 Why were the ancient Egyptians so unhealthy? 0:46:30 Nutrition and health in agriculturalists and hunter-gatherers https://www.proteinpower.com/nutrition-and-health-in-agriculturalists-and-hunter-gatherers/ 0:48:55 Earliest evidence for caries and exploitation of starchy plant foods in Pleistocene hunter-gatherers from Morocco https://www.pnas.org/content/111/3/954 0:58:53 Are peptide supplements legit? 1:03:23 Diet of ancient Egyptians inferred from stable isotope systematics https://www.sciencedirect.com/science/article/abs/pii/S0305440314000843 1:03:42 Reconstructing Ancient Egyptian Diet through Bone Elemental Analysis Using LIBS (Qubbet el Hawa Cemetery) https://www.hindawi.com/journals/bmri/2015/281056/ 1:04:38 Evidence for dietary change but not landscape use in South African early hominins https://pubmed.ncbi.nlm.nih.gov/22878716/ 1:05:10 Stable isotopes reveal patterns of diet and mobility in the last Neandertals and first modern humans in Europe https://www.nature.com/articles/s41598-019-41033-3 1:05:50 The lowdown on sulforaphane 1:07:20 Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism https://pubmed.ncbi.nlm.nih.gov/26946249/ 1:08:22 Sulforaphane Induces Oxidative Stress and Death by p53-Independent Mechanism: Implication of Impaired Glutathione Recycling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965485/ 1:14:10 Antioxidants in food: mere myth or magic medicine?

Short answer: yes!   Just because your blood calcium levels are within normal doesn’t mean you don’t need calcium in your diet.   How can you get this? If you tolerate dairy that’s a good option, but for most, I believe calcium from bones as MCHA (microcrystalline hydroxyapatite) is the best option.    That’s why we made our Bone Matrix supplement at Heart & Soil.     In this video, I discuss evidence for benefits of MCHA, if you should worry about calcium and heart attacks, and a bunch more.    Do you have a calcium source in your diet? If not, you need to check out this video and get your learn on!   For those wondering, the Hadza do eat the ends of bones from birds and small animals like Galagos, as well as breaking bones open to suck out the marrow.  #theremembering   -- Heart & Soil: http://heartandsoil.co