
Masters of Scale
On Masters of Scale, iconic business leaders share lessons and strategies that have helped them grow the world's most fascinating companies. Founders, CEOs, and dynamic innovators join candid conversations about their triumphs and challenges with a set of luminary hosts, including founding host Reid Hoffman (LinkedIn co-founder and Greylock partner). From navigating early prototypes to expanding brands globally, Masters of Scale provides priceless insights to help anyone grow their dream enterprise.
Latest episodes

42 snips
May 22, 2025 • 34min
Esther Perel: Build better relationships at work
Therapist Esther Perel, renowned for her insights on relationships, discusses building stronger workplace connections. She emphasizes the importance of relational intelligence and offers tools like her new conversational card game for colleagues. Perel dives into how AI is changing our interactions, the role of emojis in communication, and the significance of emotional dynamics in professional settings. The conversation sheds light on fostering trust, managing generational gaps, and enhancing workplace culture through effective interpersonal skills.

221 snips
May 20, 2025 • 34min
The enterprise AI revolution is underway, with Box’s Aaron Levie
Aaron Levie, Co-founder and CEO of Box, shares insights on the AI revolution reshaping enterprise dynamics. He distinguishes between the real advancements in AI and the surrounding hype. Levie discusses how AI agents enhance productivity by utilizing unstructured data, emphasizing their role in fostering growth rather than replacing jobs. He also addresses the challenges businesses face in adopting AI and the importance of adaptability. The conversation highlights the need for leaders to embrace rapid technological change and encourages a mindset resilient to disruption.

May 15, 2025 • 30min
Why we keep failing to eradicate this disease, with YouTuber John Green
John Green, a celebrated author and content creator known for works like The Fault in Our Stars, discusses his mission to eradicate tuberculosis, a disease that still claims over a million lives annually. He highlights the systemic health inequities that perpetuate TB's spread, stressing the need for innovative solutions and equitable resource distribution. Green emphasizes the power of community and creativity in tackling monumental health challenges and shares compelling personal stories from those affected, showcasing the urgent need for action.

91 snips
May 13, 2025 • 29min
The one trait every leader needs today, with General Stanley McChrystal
Retired U.S. General Stanley McChrystal, a leadership expert and author, discusses the pivotal role of character in today’s leadership landscape. He advocates for integrity amidst challenges like AI ethics and societal polarization. McChrystal emphasizes the need for courageous leadership and inclusivity, especially concerning military service. He warns against the dangers of politicizing military leadership and highlights the responsibility leaders have in leveraging AI ethically. Ultimately, he inspires leaders to uphold their values and prioritize ethical decision-making in turbulent times.

33 snips
May 10, 2025 • 37min
Replay: Banishing burnout, with Arianna Huffington
Arianna Huffington, founder of Thrive Global and co-founder of The Huffington Post, shares her transformative journey after experiencing burnout. She discusses the crucial importance of mental health for entrepreneurs and the wake-up call that led to her wellness-focused venture. Topics include innovative employee benefits like the 'Lobatical,' the powerful role of naps in boosting productivity, and strategies for maintaining work-life balance in a tech-driven world. Huffington emphasizes cultivating a culture of well-being as key to sustainable success.

40 snips
May 8, 2025 • 30min
How this first-time founder landed a $630 million exit
Ju Rhyu, co-founder of Hero Cosmetics, shares her journey from a corporate job in South Korea to launching her skincare line known for its popular acne patches. She discusses the moment she recognized a gap in the U.S. market for hydrocolloid pimple patches and how her immigrant background and father's entrepreneurial spirit influenced her. Rhyu also reflects on overcoming self-doubt, the significance of collaboration, and the emotional challenges of achieving a $630 million exit, emphasizing innovation and timing in her success.

13 snips
May 8, 2025 • 42min
Replay: Bill Gates is ending his foundation — here’s how it began
Bill Gates, co-founder of Microsoft and philanthropist, shares insights on transforming global health through the Bill & Melinda Gates Foundation. He discusses innovative solutions for public sanitation, revealing the evolution of the toilet and the pressing global sanitation crisis. Gates emphasizes the foundation's impressive impact on reducing childhood mortality and revolutionary data initiatives like minimally invasive autopsies. The conversation highlights the crucial role of partnerships and adaptive strategies in creating sustainable health outcomes worldwide.

43 snips
May 6, 2025 • 37min
Musk and DOGE: Inside 100 days of chaos, with WIRED’s Global Editorial Director Katie Drummond
Katie Drummond, Global Editorial Director of WIRED and co-host of Uncanny Valley, dives into the whirlwind of Elon Musk's influence during his time intertwined with politics. She discusses the intersection of government inefficiencies and the rise of Dogecoin, alongside the ethical dilemmas emerging from this relationship. Drummond uncovers the backlash faced by public figures linked to cryptocurrency and examines how business leaders navigate chaos and innovate in a landscape shaped by political dynamics.

18 snips
May 1, 2025 • 32min
Disrupting healthcare job hunting, with Incredible Health’s Dr. Iman Abuzeid
Dr. Iman Abuzeid, Co-founder and CEO of Incredible Health, is transforming healthcare hiring with a marketplace that addresses the industry's friction and burnout. She shares insights on the importance of understanding user needs and forming strategic partnerships. Dr. Abuzeid highlights her unique approach to scaling the business, ensuring a customer-centric culture, and the innovative 'Lobatical' program for employee appreciation. She discusses navigating competition in the job market and the challenges of expanding beyond California, all while emphasizing mentorship and emotional support for leaders.

58 snips
Apr 29, 2025 • 26min
Marc Lore wants an AI superapp to plan all your meals
Marc Lore, a billionaire entrepreneur and founder of Wonder, shares his ambitious vision for a superapp that uses AI to revolutionize meal planning. He discusses how his startup is reshaping the food industry through acquisitions like Blue Apron and Grubhub. Lore highlights the innovative integration of AI in personal nutrition, making healthy eating more accessible. He also reveals his bold move to lower prices, challenging the market norms, and emphasizes the importance of setting public goals for business success.