On this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande talk to guests Peyton Greenside and Mark DePristo of BigHat Biosciences. The conversation covers the growing role of artificial intelligence and machine learning in drug development and specifically in biologics and protein therapeutics.

Topics covered this week include:How to tell if a startup has entered  "purgatory", where they're getting by each year but no longer has a chance to be a multi-billion dollar companyCommon mistakes founders make when pitching VCsWhen do the biggest disagreements happen over possible investmentsWhat happens when an idea is great, but one of the founders is toxicIs there anyone now like Silicon  Valley coaching legend, Coach Bill Campbell?What kinds of large companies are easiest to compete with?R&D and basic research, now and thenInvesting in people, pre-ideaIf you started today with zero connections and $50k in the bank, what would you do?

On this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Julie Yoo, Vineeta Agarwala, Jorge Conde, and Vijay Pande, along with market development partner Venkat Mocherla, talk to guest Dr. Stephen Klasko, the president of Thomas Jefferson University and CEO of Jefferson Health about transforming the US healthcare system.

What are the different types of failure? Which can (and can’t) we come back from? And what does it take to turn failure into a comeback story?The second episode of “4B with Margit” explores failure and comebacks with Suneel Gupta, once a poster child for failure, featured in the New York Times and on the keynote stage of FailCon, whose new book Backable is a study in turning failure into success. Also joining the conversation is Eugene Soltes, Harvard Business School professor and author of Why They Do It: Inside the Mind of the White-Collar Criminal; Ash Spiegelberg, a partner at the Brunswick Group specializing corporate reputation and crisis management; and Carlye Adler, the Silicon Valley ghostwriter who helped Suneel with Backable.“4B with Margit” is a Clubhouse show for raw and unfiltered advice from comms and marketing experts who have seen it all, as well as insider stories from the builders and pioneers who were in the trenches. Think “Scandal” meets “Halt and Catch Fire.” Catch it live Wednesdays 4-5 PST.  

For some cloud software companies, they don't just build on AWS, Azure, or Google Cloud, they compete with them. So, how do you stay ahead when competing in the cloud?  a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, cover that, as well as getting product-market fit on your second product, why it's difficult to do both on-prem and cloud software, the importance of making the right unpopular decision, and how to know if a potential exec hire is a cultural fit on this episode of Boss Talk – the Clubhouse show where a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, discuss CEO stuff, leadership stuff, management stuff... boss stuff.  

On this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande, along with a16z cofounder Marc Andreessen, talk to guest Dr. George Church of Harvard University about past, future, and power of genome engineering.

On this episode of the new a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Jeff Jordan, and Vijay Pande, talk to guest Dr. Casey Means, co-founder of Levels Health, about metabolism and metabolic health.

Aarthi Ramamurthy and Sriram Krishnan welcome Marc Andreessen, Chris Dixon, and other experts and early adopters to discuss all things NFT (non-fungible tokens) on the Good Time Show. Guests include Mike Winkelmann (aka Beeple), the digital artist whose work is currently being auctioned at Christie's, and founders of some of the leading digital creative marketplaces including Roham Gharegozlou of Dapper Labs and Kayvon Tehranian of Foundation.

Marc Andreessen joins a16z's Head of Marketing Margit Wennmachers for the first episode of "4B with Margit" — a Clubhouse show  for raw and unfiltered advice from comms and marketing experts who have seen it all, as well as insider stories from the builders and pioneers who were in the trenches. Think “Scandal” meets “Halt and Catch Fire.” Catch it live Wednesdays 4-5 PST.  In this episode: What is a 4B? What is the playbook for dealing with a crisis? And has it changed with the rise of social media and other direct channels?How does a company or startup build its media machine? And how should they think about different channels, especially new channels like Clubhouse?When do you add internal comms? And how do you (or even should you) set a policy for individual employees on social media?  

How do you keep internal politics in check? How do you know when an employee is not working? And how do you maintain culture as you grow?  Those questions and more on the fourth episode of Boss Talk, the Clubhouse show where Ben Horowitz and Ali Ghodsi discuss CEO stuff, leadership stuff, management stuff... boss stuff.