Pioneering immunologist, Carl June, discusses his work on CAR T cell therapy, including its origins in HIV treatment, effectiveness in treating B cell malignancies, challenges with cytokine storms, and future prospects for cancer treatment advancements.

Tom Hale, CEO of ŌURA, discusses the potential of wearables to change behavior and improve health. They explore how AI can maximize wearable usefulness, impact of wearables on sleep quality, consumerization of healthcare through wearables, health monitoring studies, personal sleep tips, and the correlation between sleep and NBA player performance.

Philip Tagari, Chief Scientific Officer of insitro, and Vijay Pande discuss the transformative power of drug discovery, evolution of the process with AI, and the future of the industry. Topics include AI-enabled drug engineering, personalized healthcare, and blending tech and life sciences for optimal results.

Two healthcare innovators, Ed and Todd Park, discuss the urgent need for AI in healthcare and their journey of building Devoted Health from scratch. They emphasize aligning payment with quality care, integrating technology, and the transformative power of AI in improving patient outcomes by 2030.

Vijay Pande and Julie Yoo from a16z Bio + Health discuss grand challenges in healthcare AI, including AI integration in healthcare workflows, value-based care, and innovation in clinical trials. They also share their thoughts on the AI startups they hope to see in the industry.

Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb, discusses AI's impact on drug discovery with a16z Bio + Health partner Jorge Conde. They explore AI integration strategies, emerging modalities, and tips for startups partnering with biopharma firms.

Guests Julie Yoo and Jay Rughani from a16z Bio + Health discuss AI adoption in healthcare with executives, covering topics like improving efficiency, patient messaging, measuring tech ROI, navigating adoption challenges, and building strategic partnerships.

Exploring the biotech revolution with Vijay Pande, discussing AI impact on drug development, challenges in biotech startups, healthcare transformation through software engineering, navigating regulatory landscapes, and the evolution of healthcare towards value-based care.

Discover the hidden secrets of LINE-1 in our genome, once dismissed as junk DNA but now linked to autoimmunity, cancer, neurodegeneration, and aging. Rome Therapeutics is paving the way to target LINE-1 and other 'dark genome' factors for disease treatment, showcasing promising advancements in drug development.

Vijay Pande and Steph Smith discuss using DNA as data storage, comparing it to Moore's Law. They explore DNA's capacity, longevity, and potential for the future of biotech. The podcast covers advancements in DNA storage, challenges in DNA synthesis, and the efficiency of using DNA for data storage.